Clinical trials: Transcranial Direct Current Stimulation
Primary Progressive Aphasia
Speech-Language Treatment With Remotely Supervised Transcranial Direct Current Stimulation in Primary Progressive Aphasia
Primary progressive aphasia (PPA) is a disorder characterized by gradual decline in speech-language ability caused by underlying neurodegenerative disease.
- Trial name
- NCT05901233
- Testing
- Remotely supervised Transcranial Direct Current Stimulation (RS-tDCS), Lexical Retrieval Training (LRT), Video Implemented Script Training in Aphasia (VISTA)
- Where
- 2 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Aging
Brain Stimulation and Cognitive Training in Healthy Older Adults
The aim of this study is to investigate whether a tDCS-accompanied intensive cognitive training of working memory leads to performance improvement in healthy older individuals.
- Trial name
- TrainStim (NCT03838211)
- Testing
- Anodal tDCS, Intensive cognitive training
- Where
- Germany
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald
Cognitive Change
Cerebral Excitability and Cognitive Performance
This study investigates the perceptual and cognitive influences of low-intensity electrical brain stimulation (transcranial direct current stimulation; tDCS), versus control (sham) conditions.
- Trial name
- NCT03807934
- Testing
- Stimulation via Soterix Medical or Neuroelectrics noninvasive brain stimulation systems
- Where
- United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Tufts University
Schizophrenia, Depression
Neuromodulation in Depressed and Schizophrenic Patients - Changing MEP (Muscle Evoked Potentials) by tDCS (Transcranial Direct Current Stimulation)
Muscle evoked potentials (MEP) are supposed to different in schizophrenic and depressed patients, compared to a sample of healthy volunteers.
- Trial name
- NCT01150734
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ludwig-Maximilians - University of Munich
Healthy Adults
Investigating the Neural Correlates in Memory Retrieval After HD-tDCS
The overall objective of this study is to investigate the neural correlate in retrieval memory task. The aim of the study is to understand the undergoing changes in late positive ERP component during retrieval memory task when…
- Trial name
- NCT03319134
- Testing
- active anodal HD-tDCS, active cathodal HD-tDCS
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Dallas
Healthy Participant Study
MRI-tDCS Criticism Study
This experimental study investigated how MRI-compatible transcranial direct current stimulation (tDCS) over the left dorsolateral prefrontal cortex (DLPFC) modulates neural and cognitive responses to social criticism in healthy…
- Trial name
- NCT07406464
- Testing
- tDCS
- Where
- Belgium
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Healthy Volunteers
Effect of High-Definition Transcranial Direct Current Stimulation (HD-tDCS) on Attentional Control: an fMRI Study on Healthy Participants
In a randomized, triple-blind, sham-controlled clinical trial, we will assess the effect of a single session frontal cortex High-Definition transcranial Direct Current Stimulation (HD-tDCS) on brain activity and functional…
- Trial name
- NCT05613790
- Testing
- Active High-Definition Transcranial Direct Current Stimulation (HD-tDCS)
- Where
- Iran
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Tehran
Hemorrhagic Stroke, Hemiparesis
Dual Transcranial Direct Current Stimulation (dTDCS)-Enhanced Therapy After Hemorrhagic Strokes and VEGF
This study will evaluate the feasibility of dual tDCS to improve arm motor function in chronic stroke patients. In addition it will collect pilot data on the blood biomarkers associated with treatment effect.
- Trial name
- NCT03857243
- Testing
- dual transcranial direct current stimulation
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Genetic Predisposition
Simultaneous tDCS and Computerised Gamified Short-term Memory Task Feasibility
The goal of this observational study is to gain insight into the effects of transcranial direct current stimulation (tDCS) on short-term memory task performance and the feasibility of tDCS in overtly healthy carriers of the…
- Trial name
- ACTTDCS-FG (NCT06402266)
- Testing
- tDCS
- Where
- Denmark
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Fall, Gait, Unsteady
Non-invasive Brain Stimulation to Improve Unsteady Gait in Older Adults (StimGait)
Walking is a complex and continuous task that entails repetitive motions of the body. Relatively high gait variability sensitively predicts falls and cognitive decline in older adults.
- Conditions
- Fall, Gait, Unsteady, Mobility Limitation
- Trial name
- NCT06008431
- Testing
- Transcranial direct current stimulation (tDCS) (active)
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Hebrew SeniorLife
Mild Cognitive Impairment
Transcranial Direct Current Stimulation to Enhance Cognition in Mild Cognitive Impairment
The study will examine whether the effects of computerized brain training are enhanced when training is combined with mild brain stimulation in patients with mild cognitive impairment.
- Trial name
- NCT01653431
- Testing
- Transcranial direct current stimulation
- Where
- Australia
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- The University of New South Wales
Mild Cognitive Impairment
Improvement of Memory in Mild Cognitive Impairment
The Clinical Trial will systematically examine the feasibility of remote, caregiver-led tACS for older adults with memory deficits and evaluate whether repeated tACS leads to sustained improvement of neuronal activity and memory…
- Trial name
- NCT05708001
- Testing
- transcranial alternating current stimulation (tACS), high-density electroencephalography (hdEEG), Montreal Cognitive Assessment (MoCA)
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Lucie Bréchet
Healthy
Multifocal HD-tDCS and Motor Function
The purpose of this study is to understand how the brain controls movement and how Non-invasive Brain Stimulation (NIBS) with a technique called High-density transcranial direct current stimulation (HD-tDCS) can alter brain…
- Trial name
- NCT06561165
- Testing
- Standard HD-tDCS intervention, Multifocal network targeted HD-tDCS intervention, Functional Magnetic Resonance Imaging (fMRI)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Stroke
Augmentation of Locomotor Adaptation Post-Stroke
This project will evaluate two different methods of normalizing the center of mass acceleration (COMa) in individuals post-stroke, specifically focusing on rates and pattern of recovery to analyze walking-specific adaptations as…
- Trial name
- NCT02892084
- Testing
- tDCS
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Cerebral Vascular Accident
Brain Stimulation Enhance Post-stroke Walking Survivors and Healthy Adults
Recent studies showed that a non-invasive, low-intensity brain stimulation called transcranial direct current stimulation (tDCS) can effectively increase motor neuron excitability in the brain and therefore promotes functional…
- Trial name
- NCT06191549
- Testing
- anodal transcranial direct current stimulation (a-tDCS)
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Smoking Cessation
Reducing Tobacco Smoking: a Transcranial Direct Current Stimulation (TDCS) Telehealth Study
The study aims to evaluate the feasibility of using Dorsolateral Prefrontal Cortex (DLPFC) Transcranial Direct Current Stimulation (tDCS) as a tool to decreasing distress and cigarette smoking.
- Trial name
- NCT05460676
- Testing
- Transcranial Direct Current Stimulation (tDCS), Mindfulness
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Healthy
The Effect of Transcranial Direct Current Stimulation of the Primary Motor and Somatosensory Cortex on Pain Thresholds.
The purpose of this study is to investigate the modulatory effect of a novel tDCS configuration on the pain sensitivity in healthy subjects.
- Trial name
- NCT04658485
- Testing
- Active tDCS
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Hyperphagia, Prader-Willi Syndrome
Pilot Study of Startle-response Test to Assess Transcranial Direct Current Stimulation-induced Modulation of Hyperphagia in Prader-Willi Syndrome
The purpose of this study is to determine the effects of transcranial direct current stimulation (tDCS) as it modifies hyperphagia in obese subjects, non-obese subjects, and subjects with Prader-Willi syndrome (PWS).
- Trial name
- NCT01863017
- Testing
- tDCS
- Where
- 3 sites in United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Postural Balance
Effects of Transcranial Direct Current Stimulation on Balance of Children With Balance Deficit
Neural control of posture depends on interaction of sensory and motor information from multiple structures, including the primary motor cortex (M1).
- Trial name
- NCT04341220
- Testing
- Transcranial direct current stimulation (tDCS), Balance exercises
- Where
- Brazil
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Healthy
Efficacy of Transcranial Electrical Stimulation (tES) on Emotion Processing
The aim of this study is to assess the efficacy of transcranial Electrical Stimulation (tES) on emotion processing of healthy participants.
- Trial name
- NCT04551118
- Testing
- Transcranial alternating current stimulation (tACS) -active, Transcranial direct current stimulation (tDCS)-active
- Where
- China
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Tianjin Anding Hospital