Clinical trials: sponsored by Fujian Medical University
Breast Cancer
Internal Mammary Lymph Nodes Irradiation in High-risk Breast Cancer After Neoadjuvant Chemotherapy
The aim of this study is to explore the impact of internal mammary nodal irradiation on disease-free survival in high-risk breast cancer patients (ypN+or supra/subclavicular lymph node positive) after neoadjuvant chemotherapy.
- Trial name
- NCT06559696
- Testing
- internal mammary nodal irradiation, No internal mammary node irradiation
- Where
- China
- Volunteers
- 722 people, healthy volunteers welcome
- Sponsor
- Fujian Medical University Union Hospital
Dementia, Alzheimer Dementia (AD)
Fuzhou Aging Brain Health Initiative
The goal of this observational study is to learn about the pathophysiological characterization and evolutionary patterns of Alzheimer's disease (AD) in older adults in Fujian Province, China.
- Conditions
- Dementia, Alzheimer Dementia (AD), Mild Cognitive Impairment (MCI), Subjective Cognitive Decline (SCD)
- Trial name
- FAITH (NCT07891429)
- Testing
- Fluids biomarker and neuroimaging of AD diagnosis
- Where
- 4 sites in China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Fujian Medical University Union Hospital
Malignant Tumour
Dosimetry and Preliminary Clinical Application Study of a Novel Probe Targeting CD73
As a new CD73-targeted PET radiotracer, 68Ga-dPNE, is promising as an excellent imaging agent applicable to various cancers. In this study, we observed the safety, biodistribution and radiation dosimetry of 68Ga-dPNE in human…
- Trial name
- NCT06995976
- Testing
- 68Ga-dPNE, 18F-FDG
- Where
- China
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Prehypertension
Behaviour Change Wheel Intervention to Promote Healthy Behaviors in Adults With Prehypertension
Prehypertension is an important risk factor for developing hypertension and cardiovascular disease. Promoting healthy lifestyle behaviors among young and middle-aged adults with prehypertension may help reduce the risk of…
- Trial name
- NCT07880990
- Testing
- Behaviour Change Wheel-Based Health-Promoting Behavior Intervention, Routine Health Education
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Fujian Medical University Union Hospital
Chronic Disease, Chronic Disease Management
Taining Golden Lake Comprehensive Chronic Disease Management Initiative
This study aims to establish the first county-level, population-based prospective cohort in Taining County, Fujian Province, China. The cohort will include at least 20,000 residents aged 18 years or older.
- Conditions
- Chronic Disease, Chronic Disease Management, Hypertension, Diabetes Mellitus
- Trial name
- TAIGOLD-CDM (NCT07308314)
- Where
- China
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Cracked Tooth Syndrome
Exploration of Diagnosis, Etiology, and Prognosis Prediction of Cracked Teeth in Young Adults
Cracked teeth are a common dental problem where tiny cracks form in the teeth. These cracks can be hard to find early, and if not treated, they may cause the tooth to break.
- Trial name
- CDCP (NCT07837960)
- Testing
- Observational Assessment Only
- Where
- China
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Fujian Medical University
Risk of Dementia, Dementia
Development and Empirical Evaluation of a Brief Lifestyle Intervention for Older Adults at Risk of Dementia Within an Integrated Medical-Preventive Grid-Based Service Model
Lifestyle factors are among the most important modifiable risk factors for dementia, and primary prevention through lifestyle interventions is considered the most cost-effective approach to reducing the incidence of dementia.
- Trial name
- NCT07831616
- Testing
- Brief lifestyle intervention
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Fujian Medical University
Melasma
Stem Cell Derived Exosomes in the Treatment of Melasma and Its Percutaneous Penetration
Melasma is a refractory skin disease due to its complex pathogenesis and difficult treatment. Studies have found that human umbilical cord mesenchymal stem cell-derived exosomes (hUCMSC-Exos) could serve as a novel cell-free…
- Trial name
- NCT06221787
- Testing
- 1565 nm non-ablative fractional laser combined with normal saline, microneedles combined with hUCMSC-Exos, 1565 nm non-ablative fractional laser combined with hUCMSC-Exos
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Fujian Medical University Union Hospital
Skin Wound, Scar, Hypertrophic
Umbilical Cord Stem Cells for Skin Grafts in Donor Site Wounds
The goal of this clinical trial is to evaluate the safety and effectiveness of human umbilical cord mesenchymal stem cell (hUCMSC) therapy in patients undergoing medium-thickness skin grafts for donor site wounds.
- Trial name
- NCT05984628
- Testing
- human umbilical cord mesenchymal stem cells, blank solvent
- Where
- China
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Fujian Medical University Union Hospital
Subthreshold Depression
Effects of Virtual Reality-Based Horticultural Intervention for Older Adults With Subthreshold Depression in Nursing Homes
Subthreshold depression represents a state of psychological sub-health between normal individuals and clinical depression. It constitutes a high-risk stage for developing clinical depression and a critical phase for alleviating…
- Trial name
- NCT07275034
- Testing
- Virtual Reality-Based Horticultural Intervention System, routine health management
- Where
- China
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Fujian Medical University
PARKINSON DISEASE (Disorder)
Integrated Digital and Neurogenic Exosome Biomarkers for Early Diagnosis of Parkinson's Disease: Development and Application
Based on the high-quality Parkinson's disease cohort population and biological sample database in the early stage of the team, multi-dimensional intelligent wearable device technology and machine learning were used to screen and…
- Trial name
- NCT07679256
- Where
- China
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Fujian Medical University Union Hospital
Dementia, Primary Health Care Providers
Dementia Management Training Programme for Primary Health Care Providers
This study aims to evaluate the effectiveness and implementation outcomes of a dementia management competency training program for primary healthcare workers.
- Trial name
- NCT07617883
- Testing
- Structured Dementia Management Competency Training Program, Self-directed Dementia Learning
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Fujian Medical University
AML, Adult
Biomarkers in Bone Marrow Supernatant for Predicting AML Chemosensitivity
Chemoresistance in acute myeloid leukemia (AML) is closely associated with the bone marrow microenvironment. Elevated levels of IL-6, leptin, fumarate, and other factors within the bone marrow microenvironment have been shown to…
- Trial name
- NCT07587944
- Where
- China
- Volunteers
- 405 people, healthy volunteers welcome
- Sponsor
- Fujian Medical University Union Hospital
Melasma
Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes in the Treatment of Melasma
Melasma is a refractory skin disease with a complex pathogenesis and difficult treatment. Research has found that mesenchymal stem cell-derived exosomes have effects such as anti-wrinkle formation, anti-inflammation, antioxidant…
- Trial name
- NCT06677931
- Testing
- 1565 non-ablative fractional laser combined with umbilical cord mesenchymal stem cell-derived exosomes.
- Where
- 2 sites in China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Fujian Medical University Union Hospital
Temporomandibular Joint Disorders
Application of the Visualization of Treatment Objective (VTO) Analyses in Fabricating Anterior Repositioning Splints
This study conducted a randomized controlled clinical trial to evaluate the effect of the the therapeutic position of the anterior repositioning splint determined by VTO analyse compared with traditional method for the treatment…
- Trial name
- NCT05362201
- Testing
- therapeutic position of the anterior repositioning splints
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Fujian Medical University
Peri-implant Soft Tissue Healing
Spatiotemporal Single-cell Atlas of Peri-implant Soft Tissue Healing
This study aims to explore the dynamic changes in different cell types and their molecular regulatory mechanisms during the healing process of peri-implant soft tissues, using single-cell RNA sequencing (scRNA-seq) and spatial…
- Trial name
- NCT07279090
- Testing
- Healing Abutment Gingival Healing Post-Implantation
- Where
- China
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Stomatological Hospital Affiliated with Fujian Medical University
Education
Effect of Preoperative Individualized Education on Anxiety and Recovery.
Researchers aim to investigate whether individualized preoperative education for patients is beneficial in reducing perioperative anxiety, promoting postoperative recovery, and enhancing postoperative quality of life.
- Trial name
- NCT06419088
- Testing
- Preoperative individualized education
- Where
- China
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Fujian Medical University Union Hospital
Chronic Cough, Video-assisted Thoracoscopic Surgery (VATS)
A Prospective, Randomized, Double-blind Study on the Effects of Different Anesthesia Strategies on Postoperative Cough in Patients Undergoing Video-assisted Thoracoscopic Surgery.
This study aims to systematically evaluate the effects of different anesthesia methods on postoperative chronic cough in lung cancer patients undergoing video-assisted thoracoscopic lung resection (VATS), and to clarify the…
- Trial name
- Chronic cough (NCT07190664)
- Testing
- Patients were randomly grouped
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Fujian Medical University Union Hospital
Renal Carcinoma, Serology
Serological Autoantibodies in Early Kidney Cancer Diagnosis and Prognosis: A Multicenter Study
This project aims to construct a multicenter retrospective study by retrospectively collecting clinical, serological, and pathological data from patients.
- Conditions
- Renal Carcinoma, Serology, Autoantibody
- Trial name
- NCT06917560
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Stroke, Microbial Disease
Estimate the Relationship Between Oral Microbiota and Stroke
Oral bacteria constitute the second largest population of the human microbiome. Recent studies have identified their role in the development of systemic diseases, such as cardiovascular and cerebrovascular diseases.
- Trial name
- NCT06479915
- Where
- 2 sites in China
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Fujian Medical University