Clinical trials: sponsored by Mahidol University
Sleep, Slow-wave Sleep, Sleep Enhancement, Sleep Optimization, Sleep Inertia
Association Between Slow Wave Activity and Sleep Inertia
Observational study: The goal of this observational study is to learn about the association between slow wave activity before awakening and post-awakening psychomotor vigilance task in time-fixed, 2-hour, simulated night naps in…
- Conditions
- Sleep, Slow-wave Sleep, Sleep Enhancement, Sleep Optimization, Sleep Inertia, Night Shift Work
- Trial name
- NCT07409883
- Testing
- Nap intervention
- Where
- Thailand
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Mahidol University
HIV
HIV Self-testing With Online Supervision for Vietnamese MSM
Although global rates of HIV infection have decreased overall, rates among men who have sex with men (MSM) in Southeast Asia are increasing.
- Trial name
- NCT05797961
- Testing
- HIV self-testing with online supervision, Control
- Where
- Vietnam
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Tooth Injuries, Dental Restoration, Permanent
Colour Match, Stability, and Patient's Satisfaction of Single-Shade Composites in Anterior Teeth
The goal of this observational study is to evaluate the clinical performance of a single-shade composite resin, used with an injection moulding technique, in restoring maxillary incisors affected by traumatic dental injury in…
- Trial name
- NCT07309653
- Where
- Thailand
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Mahidol University
HIV/AIDS, STD
Addressing the Continuum of Care Among High-risk Thai Men
Young Thai men who have sex with men (YMSM) are at high risk for HIV. However, the Thailand National HIV Strategy does not adequately cover HIV prevention for YMSM using specific methods relevant to them, and instead uses a…
- Trial name
- NCT05161689
- Testing
- HUG-M+
- Where
- 2 sites in Thailand
- Volunteers
- 636 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Rehabilitation, Physical Therapy
The Combined FIFA 11+ and Change of Direction Training
The study has investigated the effects of adding change of direction (COD) training to the FIFA 11+ on lower extremity performance in soccer players.
- Trial name
- NCT06262087
- Testing
- Change of direction training, FIFA 11+ program
- Where
- Cambodia
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Perennial Allergic Rhinitis, Child, Only
As Needed Versus Regular Intranasal Corticosteroid in Children With Perennial Allergic Rhinitis
Allergic rhinitis in children is common. According to the international study of asthma and allergies in childhood (ISAAC) phase III, the global prevalence of allergic rhinitis among children is increasing to 40.1% and the…
- Trial name
- NCT05299086
- Where
- Thailand
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Slow Transit Constipation, Colonic Transit
Validation of New Type Radiopaque Marker in The Evaluation of Colonic Transit Time
The goal of this clinical trial is to learn if the local made colonic transit capsule can be use to diagnose slow transit constipation.
- Conditions
- Slow Transit Constipation, Colonic Transit, Chronic Constipation, Colonic Transit Capsule
- Trial name
- NCT06850415
- Testing
- Siriraj gastrointestinal transit capsule, Sitz-Markers
- Where
- Thailand
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Old Age, Hip Fractures
Validity and Reliability of the Modified Delirium Diagnostic Tool - Provisional (DDT-Pro) (Thai Version) in Peri-operative Fragility Hip Fracture Patient
Nowadays, the number of hip fracture patients is increasing. As Thailand enters into an aging society, hip fractures are becoming more common. They are typically treated with surgery.
- Conditions
- Old Age, Hip Fractures, Delirium
- Trial name
- NCT06504251
- Testing
- Delirium Diagnostic Tool-Provisional ( DDT-Pro )
- Where
- Thailand
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Presbyphagia, Abnormal Tongue Pressure
Effect of Biofeedback Tongue Strengthening Program on Tongue Pressure and Swallowing Performance
Aging is often accompanied by a decline in bodily functions, including the swallowing process. Tongue-strengthening exercises have been shown to improve tongue strength and thickness in healthy adults and the elderly, thereby…
- Trial name
- NCT07080996
- Testing
- Strengthening training with biofeedback, Endurance training with biofeedback
- Where
- Thailand
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Plantar Fasciitis
Plantar Heel Pain: Multisegment Foot Motion and Muscle Function, FFI Translation, and Evaluation of Treatments
Plantar fasciitis (PF) is a prevalent musculoskeletal condition of plantar heel pain (PHP) that leads to pain, functional limitations, and reduced quality of life, especially among active adults aged 25 to 65.
- Trial name
- NCT03161314
- Testing
- Strengthening exercises, Stretching exercises
- Where
- 2 sites in Thailand
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Hypercholesterolemia
How Cricket Powder Affects Gut Microbiome and Cholesterol Metabolism
Cardiovascular disease (CVD) is the leading cause of death worldwide, including in Thailand. One of the major risk factors for CVD is dyslipidemia, or abnormal levels of cholesterol and other fats in the blood.
- Trial name
- CricketOnME (NCT07009756)
- Testing
- Cricket Powder
- Where
- Thailand
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Low Back Pain
Corticospinal and Motor Behavior Responses After Physical Therapy Intervention in Patients With Chronic Low Back Pain.
This study aims to 1) determine the immediate effects of transcranial direct current stimulation (tDCS) on corticospinal excitability, lumbar multifidus muscle (LM) activation, as well as lumbar stability in patients with chronic…
- Trial name
- NCT05156242
- Testing
- Active-tDCS priming MCE, NMES priming MCE, Conventional physical therapy
- Where
- Thailand
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Community-acquired Pneumonia
Effectiveness of the PCV13 in Older Thai Adults
This is the matched 1:2 case-control study, prospectively collect case and control who are diagnosed with pneumococcal or non-pneumococcal community acquired pneumonia (CAP), accordingly from November 2023 through October 2024.
- Trial name
- NCT06279624
- Where
- Thailand
- Volunteers
- 825 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Transthyretin Amyloid Cardiomyopathy (ATTR-CM)
Thailand ATTR-CM Registry
The investigators of this registry aim to study the natural history, clinical presentation, characteristics, and imaging findings of patients diagnosed with ATTR amyloidosis in Thailand longitudinally.
- Trial name
- NCT06338696
- Testing
- No intervention
- Where
- 8 sites in Thailand
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Safety Issues, Dengue
Safety, Virological and Immunological Assessment of the Controlled Dengue Human Infection Model in Dengue-Immune Participants in Thailand (DHIT-Immune)
rDEN2Δ30-7169 is a dengue challenge strain that previously reports its viremia induction effect in participants with minimal symptoms in US flavivirus naïve participants.
- Conditions
- Safety Issues, Dengue, Viremia, Immune-related Adverse Event
- Trial name
- DHIT-Immune (NCT06908018)
- Testing
- rDEN2Δ30-7169
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Non-carious Cervical Lesion
Clinical Evaluation of Composite Restorations Using Two-steps Universal Adhesive in Non-carious Cervical Lesion (NCCL)
The goal of this clinical study is to compare the clinical performance of a new 2-steps universal adhesive in patients with non-carious cervical lesions.
- Trial name
- NCCL (NCT05573243)
- Testing
- bonding strategies
- Where
- Thailand
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Pain, Postoperative
Nefopam for Post Video-Assisted Thoracoscopic Lobectomy
Video-assisted thoracoscopic (VATs) lobectomy is mild to moderately pain procedure. For conventional thoracotomy, there are many invasive pain control such as epidural analgesia, paravertebral block.
- Trial name
- NCT04241640
- Testing
- Nefopam 20 MG/ML
- Where
- Thailand
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Fasting Before Operation
Preoperative Clear Liquid Diet Fasting; Survey Among Medical School Physician
To determine knowledge and practice about liquid diet fasting among physicians in a Quaternary-care academic center study decide: questionnaire based study to ask concerning and knowledge and practice about liquid diet fasting…
- Trial name
- NCT05877248
- Where
- 2 sites in Thailand
- Volunteers
- 273 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Health-Related Behavior
Alteration of Sweet Taste Perception After Reduction of Sweet Food and Beverage Consumption.
The goal of this clinical trial is to determine whether reducing sugar intake by 50% for 12 weeks can change sweet taste perception in healthy adults and its consequences.
- Trial name
- NCT06678386
- Testing
- 50% sugar reduction
- Where
- Thailand
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Parathyroid Hormone, Tenofovir Disoproxil Fumarate
The Effects of Vitamin D and Calcium Supplementation to Parathyroid Hormone in CHB Patients Treated With TDF
Nucleot(s)ide is an antiviral drug that can reduce the number of viruses, reduce the risk of HCC, regress hepatic fibrosis and reduce death from Hepatitis B viral infection.
- Conditions
- Parathyroid Hormone, Tenofovir Disoproxil Fumarate, Chronic Hepatitis B Virus, Vitamin D
- Trial name
- TDF (NCT05313477)
- Testing
- Ergocalciferol Capsules, Calcium carbonate
- Where
- Thailand
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Mahidol University