Clinical trials: sponsored by Samsung Medical Center
Gastric Cancer, Colorectal Cancer
Development and Utilization of an Integrated Clinical Genomic Database
This observational study aims to develop an integrated genomic and clinical database to support the discovery and validation of biomarkers for cancer diagnosis, treatment selection, and prediction of treatment response.
- Conditions
- Gastric Cancer, Colorectal Cancer, Lung Cancer (NSCLC), Liver Cancer
- Trial name
- SMC-4S (NCT07911267)
- Where
- South Korea
- Volunteers
- 118,750 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Communication
Effect of an AI Agent on Caregiver Communication Experience in the Pediatric Emergency Department
This single-center, single-blind, randomized controlled trial evaluates whether the use of a conversational large language model (LLM)-based AI agent, used by caregivers during the waiting period before physician consultation in…
- Trial name
- PED-AI (NCT07867782)
- Testing
- AI Agent (conversational LLM pre-consultation history-taking tool)
- Where
- South Korea
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Pediatric Advanced Life Support (PALS)
Comparing the Effectiveness of Large Language Model-Based and Video-Based Refresher Education on Knowledge Retention After Simulation-Based Pediatric Cardiopulmonary Resuscitation Training: A Six-Month Follow-Up Study
This study aims to compare the effectiveness of large language model (LLM)-based refresher education and video-based refresher education for maintaining knowledge and performance after simulation-based Pediatric Advanced Life…
- Trial name
- NCT07783932
- Testing
- LLM-Based Refresher Education, Video-Based Refresher Education
- Where
- South Korea
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Ambient AI System, Emergency Department
Evaluation of a Generative AI-Based Voice Documentation System for Patient-Clinician Communication in the Emergency Department and Its Impact on Clinical Workflow Efficiency and Usability
This research study at Samsung Medical Center evaluates the impact of Ambient AI system, a Generative AI-based communication and documentation system developed by NAVER, on the efficiency and quality of medical record-keeping…
- Conditions
- Ambient AI System, Emergency Department, Generative ai
- Trial name
- CLOVA Charty (NCT07637591)
- Testing
- VoiceEMR
- Where
- South Korea
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Lung Adenocarcinoma
Osimertinib to Suppress the Progression of Remaining GGN for EGFR Mutation-positive Stage IB-IIIA Lung Adenocarcinoma
This is an open label, phase II study to assess the efficacy of osimertinib (80 mg, orally, once daily) to suppress the progression of remaining GGN(s) in other lobes following surgical resection for actionable EGFR…
- Trial name
- NCT05528458
- Testing
- Osimertinib 80Mg Tab
- Where
- South Korea
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Breast Neoplasms, Breast Cancer
Comparison of Ultrasound and Breast MRI for Breast Cancer Detection
The goal of this randomized clinical trial is to compare diagnostic results of secondary breast cancer surveillance using breast ultrasound abbreviated MRI and full protocol MRI.
- Trial name
- NCT05797545
- Testing
- Breast MRI for Breast Cancer Detection
- Where
- 3 sites in South Korea
- Volunteers
- 1,756 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Pediatric Patients, Pediatric Patients in Hospital Settings
Impact of Conversational Approaches in Pediatric Social Robot-Mediated Interventions
This study examines how different robot dialogue systems (rule-based vs. large language model-based) and content types (emotional support vs.
- Conditions
- Pediatric Patients, Pediatric Patients in Hospital Settings, Hospitalized Children
- Trial name
- PRIA (NCT07389902)
- Testing
- Robot-Mediated Emotional Support Activity, Robot-Mediated Safety Education Activity
- Where
- South Korea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Back Pain, Exoskeleton Device
Effects of Wearable Passive Back Support Suit on Back Pain in Caregivers
The physical demands of patient transport, including lifting and transferring patients, are significant contributors to the high risk of musculoskeletal disorders.
- Trial name
- back pain (NCT07333157)
- Testing
- wearable passive back support suit, traditional lumbosacral orthosis
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Healthy
Remimazolam Versus Midaszolam for Sedation in Diagnostic Upper Gastrointestinal Endoscopy
The goal of this clinical trial is to compare the efficacy of remimazolam with midazolam in patients undergoing gastrointestinal endoscopy.
- Trial name
- NCT05836545
- Testing
- Remimazolam, Midazolam
- Where
- South Korea
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Telemedicine, Ultrasonography
Tele-education in Ultrasound Training
The study aims to assess the impact of remote guidance in ultrasound training for medical professionals new to abdominal ultrasound.
- Conditions
- Telemedicine, Ultrasonography, Education, Medical, Continuing
- Trial name
- NCT06171828
- Testing
- Head-Mounted Display (HMD) to communicate with a supervisor remotely
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Cervix Cancer, Radiotherapy, Adjuvant
Postoperative Hypofractionated Intensity-modulated Radiation Therapy with Concurrent Chemotherapy in Cervical Cancer
To investigate the acute toxicities, late toxicities, and treatment results when the early cervical cancer patients are treated by concurrent chemotherapy with hypofractionated intensity-modulated radiotherapy (2.5 Gy X 16…
- Conditions
- Cervix Cancer, Radiotherapy, Adjuvant, Radiotherapy, Intensity-Modulated, Hypofractionated Dose
- Trial name
- NCT03239613
- Testing
- POHIM-CCRT
- Where
- South Korea
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Cervix Cancer, Radiotherapy, Adjuvant
Postoperative Hypofractionated Intensity-modulated Radiation Therapy in Cervical Cancer
To investigate the acute toxicities, late toxicities, and treatment results when the early cervical cancer patients are treated by hypofractionated intensity-modulated radiotherapy (2.5 Gy X 16 fractions, once a day) after…
- Conditions
- Cervix Cancer, Radiotherapy, Adjuvant, Radiotherapy, Intensity-Modulated, Hypofractionated Dose
- Trial name
- NCT03239626
- Testing
- POHIM-RT
- Where
- South Korea
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Nursing, Education
Utilizing of Augmented Reality Technology Education Program for Nurse
It is important to provide practice-oriented education for nurses in a safe environment. As it became difficult to maintain face-to-face education and practice environment due to COVID-19, a new paradigm for nurse education was…
- Trial name
- NCT05629663
- Testing
- AR guidance with Hololens 2
- Where
- South Korea
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Epilepsy
A Study on Telemedicine Applied to Actual Outpatient Clinic for Epilepsy
This is an observational study to confirm the non-inferior effectiveness on health outcomes of tele-counseling or tele-prescription, which was the first outpatient system applied to the actual medical sites in Korea during the…
- Trial name
- NCT05418257
- Testing
- (exposure) telemedicine
- Where
- South Korea
- Volunteers
- 307 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
HER2-positive Breast Cancer
The Resistance Mechanism of Trastuzumab Deruxtexan in HER2 Positive Breast Cancer Patients.
This study is the spatial transcriptomic approach for revealing the resistance mechanism of trastuzumab deruxtexan in HER2 positive breast cancer patients.
- Trial name
- NCT06330012
- Testing
- GeoMx data analysis with clinical outcome
- Where
- South Korea
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Aging
Long-term Exercise Effect of EX1 Exercise Program
The purpose of this study was to investigate the effect of a long-term exercise program using a wearable exoskeleton robot (EX1) on muscular strength in healthy adults aged 19 to under 65 years, compared to an exercise program…
- Trial name
- NCT05862077
- Testing
- Wearable Hip Assist Robot(EX1), Exercise Program 1, Exercise Program 2
- Where
- South Korea
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Triple Negative Breast Cancer, Immune Checkpoint Inhibitor
LAG3 Expression in Triple Negative Breast Cancer
This study is the experimental study for relationship between LAG-3 expression / immue checkpoint protein expression and neoadjuvant chemotherapy plus immune checkpoint inhibitor in triple negative breast cancer.
- Trial name
- NCT06259162
- Testing
- LAG-3 expression / immune checkpoint protein expression
- Where
- South Korea
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Prostate Neoplasm
COHORT Trial in Clinical Pelivc Lymph Node Metastatic Prostate Cancer
In local advanced prostate cancer patients with clinically positive metastatic regional lymph node, the optimal treatment is still unanswered.
- Trial name
- NCT03241537
- Testing
- Intensity modulated radiotherapy
- Where
- South Korea
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Medical Informatics, Pediatric Emergency Medicine
Mobile Chat Service for Parents of Children in Pediatric Emergency Room
The goal of this clinical trial is to test giving all medical/non-medical information in the pediatric emergency room(ER). Main questions it aims to answer are: Does providing medical/non-medical information to parents of…
- Conditions
- Medical Informatics, Pediatric Emergency Medicine, Emergency Medicine
- Trial name
- NCT06002542
- Testing
- Information provided, Control
- Where
- South Korea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Triple Negative Breast Cancer, HER2-positive Breast Cancer
Exosome as the Prognostic and Predictive Biomarker in EBC Patients
This study is the experimental study for serial ctDNA and exosome evaluation in EBC patients
- Trial name
- NCT05955521
- Testing
- exosome and ctDNA evaluation
- Where
- South Korea
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center