Clinical trials: sponsored by University Hospital, Grenoble
Healthy Subjects (HS), Exercise
Methodological Study of Exercise and Hypoxic Conditions in Healthy Subjects
The aim of this protocol is to assess physiological responses during various physical exercise protocols (whole-body exercise such as cycling or treadmill running, or localised exercise such as knee extension) and during…
- Conditions
- Healthy Subjects (HS), Exercise, Hypoxia
- Trial name
- ExHyp (NCT07671638)
- Testing
- Exercise and hypoxia
- Where
- France
- Volunteers
- 305 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Arthrogryposis Multiplex Congenita (AMC)
Technical Feasibility Study of Ultrasound Muscle Imaging in Antenatal Ultrasound
The objective of the study is to evaluate the performance of muscle ultrasound sections on antenatal ultrasound between 21-24 amenorrhea weeks for the screening of muscle atrophy, in a sample of low-risk and high-risk pregnancies…
- Trial name
- FetUS (NCT06130592)
- Testing
- ultrasound muscle imaging technique
- Where
- 2 sites in France
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Corticospinal Excitability, Cortical Activation
LAnguage-Motor Imagery Circuits to Improve Motor Learning and Language Comprehension
Recent evidence suggests that cognitive systems do not operate in isolation but interact within broader networks, thus opening new avenues for fundamental and clinical research.
- Trial name
- LAMI (NCT06478303)
- Testing
- Motor imagery, Action reading, Motor localizer
- Where
- 2 sites in France
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Autism Spectrum Disorder
Flexibility and the Predictive Brain in Autistic Males and Females
The goal of this study is to compare the neural correlates of predictive brain mechanisms during high-level social and non-social flexibility tasks, between autistic and non-autistic males and females.
- Trial name
- FLEX-PREAU (NCT06391684)
- Testing
- Social/non social; predictable vs unpredictable
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Burnout, Caregiver
Evaluation of the CBSM Program Online and in Person to Reduce Caregiver Burnout
Professional burnout is a common syndrome among healthcare workers, impacting both their well-being and the quality of care provided .
- Trial name
- Caregiver-CBSM (NCT06626061)
- Testing
- Cognitive Behavioral Stress management in in person group Format, Cognitive Behavioral Stress management Hybrid Format
- Where
- 2 sites in France
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
MRI, Sequence Optimization
Development of MRI Protocols and Associated Neuro-physiological Explorations in Healthy and Pathological Subjects
IRMaGe is a Joint Service Unit (UMS) which provides users of brain exploration equipment (clinical MRI and preclinical, TMS, EEG, NIRS and metabolomics).
- Conditions
- MRI, Sequence Optimization, Physiological Measurement
- Trial name
- MAP-IRMaGE (NCT05036629)
- Testing
- MRI Protocol
- Where
- France
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
PARKINSON DISEASE (Disorder)
The Role of Priors in Hallucinatory Perception in Parkinson's Disease
The goal of this observational study is to better understand the mechanisms of hallucinations in patients with Parkinson's disease.
- Trial name
- LEAP-PARK (NCT07427498)
- Where
- 2 sites in France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Healhty
Validation of a New System for Measuring Ventilation and CO₂ Production
Gas exchange measurement systems are complex and require specialized facilities and expertise. As a result, access to these measurements remains limited, particularly in the field of sports performance.
- Trial name
- PAIRFS (NCT07677241)
- Testing
- ZoneX
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Aging, Visual Perception
RePer-AGE: Reorganization of Visuo-cognitive Functions Based on Peripheral Vision With Aging
The RePer-AGE study investigates how central and peripheral vision contribute to visual recognition and how these mechanisms change with normal aging.
- Conditions
- Aging, Visual Perception, Cognition
- Trial name
- RePer-AGE (NCT07727369)
- Testing
- Psychophysical visual recognition tasks, Ophthalmological assessment, Functional magnetic resonance imaging (fMRI)
- Where
- France
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Multitasking Behavior and Multitasking Ability, Clinical Performance
Clinical Performance and Multitasking in Anesthesia : a Simulation-based Study
Cognitive failure under multitasking conditions has been demonstrated in various settings, including healthcare. However, in anesthesiology, the impact of multitasking on clinical performance has not yet been fully characterized.
- Conditions
- Multitasking Behavior and Multitasking Ability, Clinical Performance, Simulation Training, Simulation Based Medical Education
- Trial name
- FOCUS (NCT07615582)
- Testing
- Multitasking
- Where
- France
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Alzheimer s Disease
The Monument Test : A New Tool for Assessing the Ability to Name and Identify Unique Entities. (TeDIMO)
The goal of this study is to show a significant difference in performance between 2 groups of participants (healthy elderly people vs. people with Alzheimer Disease) in an identification and naming task involving famous monuments.
- Trial name
- TeDIMO (NCT07367880)
- Testing
- Identification and naming task
- Where
- France
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Hypoxia, Cerebral Hypoxia
Effect of Hypoxic Conditioning on Cerebrovascular Health in the Elderly
In line with the ever-growing aging of Western populations, the development of preventive strategies to slow down the effects of aging on cardiovascular health represents a major challenge in order to preserve functional…
- Conditions
- Hypoxia, Cerebral Hypoxia, Brain Diseases, Exercise
- Trial name
- HYPOXAGE (NCT05048680)
- Testing
- Hypoxia and/or Exercise
- Where
- France
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Alzheimer Disease
Validation of an Alzheimer's Disease Marker by Fecal Assay of Amyloid Peptides and Tau Proteins
Alzheimer's disease (AD) is the leading cause of dementia in humans, currently affecting almost one million people in France. It results from an irreversible degeneration of neurons responsible for a progressive decline in the…
- Trial name
- FecAlz (NCT06481878)
- Testing
- faecal analysis
- Where
- France
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Calcifications, Vascular
Ultrasound Assessment of Arterial Medial Calcification in Endurance Athletes: A Prevalence Study
Medial arterial calcification (MAC) is an under-recognized vascular condition that remains poorly characterized from an epidemiological perspective.
- Trial name
- EMASE (NCT07419126)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Healthy Volunteers
High Dimensional Computing Gesture Recognition
The primary objective of this study is the Improvement of gesture recognition and classification accuracy through the use of the HDC algorithm compared to other classification methods (KNN, RF, SGD, NC).
- Trial name
- HDC-GCog (NCT07155460)
- Testing
- HDC-GCog
- Where
- France
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Physical Exertion
Internal Discourses and Perception of Trail-running Effort
Determination of the effect of an intervention to develop the use of internal discourses on the perception of exercise during a sub-maximum effort following a trail running
- Trial name
- UT4M2022 (NCT05389111)
- Testing
- Internal discourses, Non internal discourses
- Where
- France
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Muscle Fatigue
Physiological Constraints Associated With Trail Running
The practice of mountain running or "trail" is in full development in France and elsewhere in the world. This sporting practice associates specific physiological constraints related in particular to the duration of the efforts…
- Trial name
- UT4M2018 (NCT03712592)
- Testing
- Pre and post running evaluations
- Where
- France
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Physiology
Effect of NO Precursors on Physiological Responses to Exercise
NO is an ubiquitous molecule contributing to many physiological functions such as vasodilation, immune and oxidative stress responses.
- Trial name
- NO-SUP (NCT02850367)
- Testing
- Nitrate, Nitrate and L-Arginine, Nitrate and L-Citrulline
- Where
- France
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Subclinical Cardiovascular Impairments, Obstructive Sleep Apnea Syndrome
Cardiovascular Impairments and Obstructive Sleep Apnea Syndrome
Which are the anthropometric parameters and/or of severity of the syndrome of apnea of sleep (SAS) which make it possible to anticipate occurred of vascular anomalies, anatomical and/or functional precociously found among…
- Trial name
- INFRASAS (NCT01089257)
- Where
- 3 sites in France
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Blood Gas Monitoring, Transcutaneous
Optical Transcutaneous Sensors of Capnia and Oxygenation
This study aims at validating new optical transcutaneous sensors to evaluate tissue capnia (CO2 partial pressure) and oxygenation (blood oxygen saturation) by comparing them to standard laboratory measurements (end tidal CO2…
- Trial name
- CTCO (NCT03992651)
- Testing
- Measurements of capnia and tissue oxygenation by optical transcutaneous sensors
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble