Clinical trials: sponsored by Fox Chase Cancer Center
Cancer
eHealth Delivery Alternative for Cancer Genetic Testing for Hereditary Cancer
This randomized non-inferiority study will use a 2x2 design where traditional standard-of-care pre-test (visit 1) and post-test (visit 2: disclosure) counseling delivered by a genetic counselor are replaced with a self-directed…
- Trial name
- eReach2 (NCT05427240)
- Testing
- Pre-Test Intervention, Standard of Care, Post-Test Intervention
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Abramson Cancer Center at Penn Medicine
Non Small Cell Lung Cancer
Blood Testing to Detect Cancer Recurrence in Patients With Early-Stage Non-Small Cell Lung Cancer
This observational study will evaluate whether a blood test can detect the return of non-small cell lung cancer at least three months before it is identified on routine imaging.
- Trial name
- NCT07854769
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Fox Chase Cancer Center
Uterine Cervical Neoplasm
HPV Self-sampling for Underscreened Latinas
The goal of this study is to learn if women of Hispanic/Latina ethnicity are willing to self-collect a cervico-vaginal sample for HPV testing.
- Trial name
- NCT06439706
- Testing
- HPV Self-Sampling, Group Education
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Fox Chase Cancer Center
Urothelial Cancer, Renal Pelvis Cancer
A Genotype-Phenotype Urothelial Cancer Registry
This study is being done to create a registry to help us learn more about urinary and other cancers. This will let us look at large groups of people who do and do not have this kind of cancer.
- Conditions
- Urothelial Cancer, Renal Pelvis Cancer, Ureter Cancer, Bladder Cancer
- Trial name
- NCT00902590
- Testing
- saliva sample and questionaire, saliva sample, questionaire
- Where
- 4 sites in United States
- Volunteers
- 3,519 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Lung Cancer
Pilot Study of Biopsy Scanner for Evaluation of Bronchoscopic Small Biopsy Specimens to Determine Adequacy
The aim of the study is to assess the performance of Aquyre Biopsy Scanner technology (the FDA class I medical device) at determining if tissue from the lymph nodes and lung nodules, taken during a bronchoscopy procedure, is…
- Trial name
- NCT05393154
- Testing
- Biopsy Adequacy Evaluation by Aquyre Biopsy Scanner
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Aquyre Bioscience, Inc
Cancer
Engaging and Activating Cancer Survivors in Genetic Services Study
To address the gap in access to genetic services, this study will evaluate the effectiveness of an adapted model of remote delivery of genetic services to increase the uptake of recommended genetic assessment and testing in…
- Trial name
- ENGAGE (NCT04455698)
- Testing
- Remote Telegenetic Counseling by Phone, Remote Telegenetic Counseling by Videoconferencing, Usual Care Arm
- Where
- 3 sites in United States
- Volunteers
- 511 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Cancer
Genetic Information for Families After Tumor Testing Study
The purpose of this study is to develop and implement a methodology of digital tools paired with telemedicine to improve cascade testing for clinically significant germline mutations among family members of children with cancer…
- Trial name
- GIFTT (NCT07517666)
- Testing
- Interactive Chatbot
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Abramson Cancer Center at Penn Medicine
Uterine Cervical Neoplasms
Evidence-Based Approach to Empower Asian American Women in Cervical Cancer Screening
This is a randomized trial to evaluate the effects of a community-based intervention on increasing cervical cancer screening rates in underserved Asian American (Korean, Vietnamese, and Chinese) women.
- Trial name
- NCT04557423
- Testing
- Community-Based Education, Navigation to Screening, HPV Self-Sampling
- Where
- United States
- Volunteers
- 797 people, healthy volunteers welcome
- Sponsor
- Fox Chase Cancer Center
Cancer
Implementation of eHealth Delivery Alternatives for Cancer Genetic Testing for Hereditary Cancer (eREACH3)
The purpose of the study is to understand patient interest in telehealth and digital tools for pre-test genetic education and/or disclosure of genetic test results.
- Trial name
- eREACH3 (NCT07471958)
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Abramson Cancer Center at Penn Medicine
Neoplasm
CARE Study: Cancer, Asian Americans, and Relationship Enrichment
The overarching goal of the current study is to reduce the burden Asian American patients may feel are on their caregivers by designing and testing the feasibility and efficacy of a positive activity intervention designed to…
- Trial name
- CARE (NCT06782581)
- Testing
- Contribution to Caregivers Well-Being, Control
- Where
- United States
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- Fox Chase Cancer Center
Lynch Syndrome
Atorvastatin ± Aspirin in Lynch Syndrome Syndrome
The goal of this study is to investigate that a common cholesterol lowering agent (atorvastatin) alone or combining with a nonsteroidal anti-inflammatory drug (aspirin) would reduce the risk of colorectal cancer (CRC) in…
- Trial name
- NCT04379999
- Testing
- Atorvastatin 20mg, Atorvastatin 20mg AND Aspirin 325 mg
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Fox Chase Cancer Center
Cancer
Study of an eHealth Delivery Alternative for Cancer Genetic Testing for Hereditary Predisposition in Metastatic Cancer Patients
This study aims to determine if web-based eHealth delivery of pre-test and/or post-test counseling in cancer patients and/or those at risk for cancer can provide equal or improved cognitive and affective outcomes when compared to…
- Trial name
- eReach (NCT04353973)
- Testing
- Pre-Test Intervention, Standard of Care, Post-Test Intervention
- Where
- United States
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- Abramson Cancer Center at Penn Medicine
Colorectal Cancer
Increasing Colorectal Cancer (CRC) Screening Among Hispanic Primary Care Patients
This study is designed to test a standard mailed intervention (SI) versus a novel decision support and navigation intervention (DSNI).
- Trial name
- NCT02272244
- Testing
- Decision Support & Navigation, Standard
- Where
- 3 sites in United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Liver Cancer
Liver Cancer Community Education
This study proposes to bridge the gap between evidence and action and combat rising liver cancer rates attributed to Hepatitis B and C infection in Philadelphia by identifying neighborhoods with higher than expected rates of…
- Trial name
- NCT04272619
- Testing
- LIVE-R Life Education
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Fox Chase Cancer Center
Cervical Cancer, Papilloma Viral Infection
Reducing Urban Cervical Cancer Disparities
This study uses a hybrid Type 1 effectiveness-implementation trial to operationalize and assess the efficacy of the Health Enhancement Resource System (HERS) intervention.
- Trial name
- NCT06416150
- Testing
- Stage 1 SOC, Stage 1 HERS, Stage 2 HERS
- Where
- 3 sites in United States
- Volunteers
- 546 people, healthy volunteers welcome
- Sponsor
- Fox Chase Cancer Center
Retroperitoneal Liposarcoma, Soft Tissue Sarcoma
Genomic Risk in Retroperitoneal Sarcoma
The protocol intends to explore the biology which may underlie recurrences of retroperitoneal liposarcoma. Surgery remains the only curative intent intervention for this disease.
- Trial name
- NCT06436846
- Testing
- Biospecimen sample collection during standard-of-care surgery
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Fox Chase Cancer Center
Prostate Cancer
Reducing the Effects of Active Surveillance Stress, Uncertainty and Rumination Thru Engagement in Mindfulness Education
We propose to examine the efficacy of couples-based mindfulness-based stress reduction (MBSR) on positive and negative psychological responses to active surveillance (AS) and AS adherence, with a sample of men on AS and their…
- Trial name
- REASSUREME (NCT02871752)
- Testing
- Health promotion
- Where
- 4 sites in United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Breast Cancer
Clinician Communication About Sexual Health
The objective of this study is to adapt a previously tested brief intervention aimed at enhancing clinicians communication about sexual health (iSHARE) to a mobile web-based platform showcasing a two-part podcast and to assess…
- Trial name
- NCT04262219
- Testing
- iShare
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Fox Chase Cancer Center
Prostate Cancer, Sexual Dysfunction and Infertility
Intimacy-Enhancing Couples' Intervention for Localized Prostate Cancer
RATIONALE: Participating in a therapy program may enhance communication and intimacy between men with prostate cancer and their partners.
- Conditions
- Prostate Cancer, Sexual Dysfunction and Infertility, Sexuality
- Trial name
- NCT01982058
- Testing
- communication intervention, counseling intervention, nutrition intervention
- Where
- 6 sites in United States
- Volunteers
- 483 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Diabetes Mellitus, Type 2
A Biobehavioral Model of Diabetes Risk in Chinese Immigrants
This prospective, longitudinal study of Chinese American immigrants will examine whether psychosocial factors (e.g., acculturative stress, social isolation, discrimination) are associated with markers of type 2 diabetes risk over…
- Trial name
- NCT02449213
- Where
- United States
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- Fox Chase Cancer Center