Clinical trials: sponsored by GE Healthcare
Healthy Volunteers
A Phase 1, Dose-Escalation, Positron Emission Tomography Study to Assess the Safety, Pharmacokinetics, Dosimetry and Biodistribution of GEH200521 (18F) Injection Co-Administered With GEH200520 Injection in Healthy Volunteers
This is a Phase 1, single-center, open-label, single-arm, dose-escalation positron emission tomography study to assess the safety and tolerability, immunogenicity, Pharmacokinetics, dosimetry, and biodistribution after GEH200521…
- Trial name
- NCT06398730
- Testing
- GEH200520 Injection and GEH200521 (18F) Injection, Static - PET/CT scan
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- GE Healthcare
PET/CT
Positron Emission Tomography/Computed Tomography (PECT/CT) Double-Scanning Study
This study aims to collect clinical image data using the Omni 128 cm PET/CT system and compare image quality and performance with clinically indicated PET/CT examinations.
- Trial name
- NCT07857161
- Testing
- Omni 128cm PET/CT
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- GE Healthcare
Hemostasis, Blood Biomarkers
Ultrasound of the Spleen Utilizing Low-energy (Diagnostic Level) Insonification.
This is a three-cohort, randomized, double-blinded , sham-controlled, single-center, early feasibility research trial to determine whether organ-specific biologic effects on platelet activity and coagulation are achievable…
- Conditions
- Hemostasis, Blood Biomarkers, Ultrasound
- Trial name
- NCT06934096
- Testing
- Ultrasound Pulsed Doppler Imaging System
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Computed Tomography
Data Collection of New Spectral CT Imaging Method
The purpose of the study is to collect data to evaluate utility of a next generation spectral CT system in a clinical setting.
- Trial name
- NCT07661706
- Testing
- Research CT
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- GE Healthcare
SPECT-CT
Single Photon Emission Computed Tomography/Computed Tomography (SPECT/CT) Prospective Double-Scanning Study
The goal of this study is to collect image data for the StarGuide GX Single Photon Emission Computed Tomography/Computed Tomography (SPECT/CT) System in a clinical setting.
- Trial name
- NCT07725237
- Testing
- StarGuide GX SPECT/CT Scan
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- GE Healthcare
Breast Cancer
Comparison of Breast Cancer Screening With CESM to DBT in Women With Dense Breasts
The over-arching goal of the Contrast-Enhanced Spectral Mammography Imaging Screening Trial (CMIST) is to determine if dual-energy contrast-enhanced spectral mammography (CESM) can detect more cancers with fewer false positives…
- Trial name
- CMIST (NCT05625659)
- Testing
- Dual-Energy Contrast-Enhanced Spectral Mammography (CESM)
- Where
- 13 sites in United States, Canada
- Volunteers
- 2,032 people, healthy volunteers welcome
- Sponsor
- American College of Radiology
CT Photon-Counting
Clinical Feasibility and Evaluation of Silicon Photon Counting CT
The purpose of the study is to collect data to evaluate utility of the using photon-counting CT in a clinical setting.
- Trial name
- NCT05838482
- Testing
- CT Photon-Counting
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- GE Healthcare
Fetal Monitoring
Evaluation of the Goldcrest Patch Performance
The Novii Patch is an accessory to the Novii+ Pod that connects directly to the Novii+ Pod and contains the surface electrodes that attach to the abdomen.
- Trial name
- NCT06355453
- Testing
- Goldcrest Patch and Three Patch Coupons, Goldcrest Patch and Novii Patch
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- GE Healthcare
Blood Pressure, Blood Pressure Measurement
NIBP Cuff Comparison Study
The purpose of the study is to compare NIBP cuff materials and their effect on the measurement results.
- Trial name
- NCT07024472
- Where
- 2 sites in Finland
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- GE Healthcare
Nonalcoholic Fatty Liver, Nonalcoholic Steatohepatitis
Conditionally Increased Output (CIO) Enhanced Ultrasound System
This study aims to assess possible bioeffects that may be caused by the use of shear wave elastography (SWE) with conditionally increased acoustic output pressure (CIO).
- Conditions
- Nonalcoholic Fatty Liver, Nonalcoholic Steatohepatitis, Fatty Liver
- Trial name
- NCT05792423
- Testing
- GE ultrasound system with increased acoustic output settings
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
SpO2, Peripheral Oxygen Saturation Measurement
Wireless Disposable SpO2 Sensor Hypoxia Testing
The purpose of the study is to collect SpO2 data with simultaneous transfer standard SpO2 measurements data on human participants.
- Trial name
- SpO2 Dispo (NCT06211530)
- Testing
- SpO2 Sensor Testing
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- GE Healthcare
Coronary Heart Disease
Cadmium-zinc-telluride (CZT) Imaging of Myocardial Blood Flow (MBF) (SPECT MBF)
This study is being done to compare the blood flow measurements obtained with the SPECT and PET imaging scans. Measurements such as myocardial blood flow (MBF) and myocardial flow reserve (MFR) are analyzed on PET scans.
- Trial name
- SPECTMBF (NCT02280941)
- Testing
- single photon emission computed tomography
- Where
- Canada
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Ottawa Heart Institute Research Corporation
Colorectal Cancer
Virtual Colonoscopy Using Omnipaque as a Contrast Agent
CT colonography (CTC) is a validated screening exam for colorectal cancer. The diagnostic accuracy of CTC depends on the quality of the bowel cleansing and contrast tagging of residual stool and fluid.
- Trial name
- NCT04582500
- Testing
- Iohexol
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Pregnancy, High Risk, Telemonitoring
Remote Telemedicine Fetal Monitoring Feasibility Study
During pregnancy, certain conditions may arise that mean regular monitoring of both mother and baby are needed to ensure timely interventions and avoid the need for further treatments.
- Conditions
- Pregnancy, High Risk, Telemonitoring, Telemedicine, Ultrasound
- Trial name
- NCT06366711
- Testing
- Pregnabit Pro device and PregnaOne platform, Pulsenmore device
- Where
- United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Birmingham Women's NHS Foundation Trust
Alzheimer Disease, Mild Cognitive Impairment
BioFINDER-Brown: Examination of Alzheimer's Disease Biomarkers
This research study aims to examine biomarkers of Alzheimer's disease as early as possible which could potentially be a screening tool for the general population.
- Conditions
- Alzheimer Disease, Mild Cognitive Impairment, Dementia
- Trial name
- NCT05457998
- Testing
- Flutemetamol F18 Injection, [18F]-RO6958948 Injection, [18F]-MK-6240 Injection
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Butler Hospital
Healthy, Insulin Resistance
Effects of Hepatic Ultrasound on Metabolic Homeostasis
The purpose of this study is to define the effect of ultrasound exposure of the liver in the region of the porta hepatis on glucose homeostasis and insulin resistance in healthy subjects.
- Trial name
- NCT04622683
- Testing
- Ultrasound
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Yale University
Non-Alcoholic Fatty Liver Disease, Non-alcoholic Steatohepatitis
Technical Validation of MR Biomarkers of Obesity-Associated NAFLD
The overall goal of this collaborative research program is to develop, validate and translate advanced quantitative magnetic resonance (MR) biomarkers of obesity-associated non-alcoholic fatty liver disease (NAFLD).
- Trial name
- NAFLD (NCT03674528)
- Testing
- Magnetic Resonance Elastography (MRE), Liver biopsy
- Where
- 2 sites in United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Alzheimer's Disease, Mild Cognitive Impairment
BEAM: Brain-Eye Amyloid Memory Study
The main objectives for this study are: 1. To investigate novel, non-invasive ocular measurements including optical coherence tomography and eye tracking in a cross-sectional study of participants with various neurodegenerative…
- Conditions
- Alzheimer's Disease, Mild Cognitive Impairment, Vascular Cognitive Impairment, Parkinson's Disease
- Trial name
- BEAM (NCT02524405)
- Testing
- Pittsburgh Compound B [11C]-PIB
- Where
- 5 sites in Canada
- Volunteers
- 345 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Parkinsonian Syndrome, Parkinson Disease(PD)
A Study to Evaluate the Diagnostic Efficacy of DaTSCAN™ Ioflupane (123I) Injection in Single Photon Emission Computed Tomography (SPECT) for the Diagnosis of Parkinsonian Syndrome (PS) in Chinese Patients
This is a multicenter, open-label, non-controlled, non-randomized, phase 3 clinical study to compare the SPECT findings after a single IV administration of DaTSCAN™ ioflupane (123I) injection for patients with a clinical…
- Conditions
- Parkinsonian Syndrome, Parkinson Disease(PD), Multiple System Atrophy (MSA), Progressive Supranuclear Palsy (PSP)
- Trial name
- NCT04193527
- Testing
- DaTSCAN™ Ioflupane (123I) Injection
- Where
- 10 sites in China
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- GE Healthcare
Healthy Subjects (HS)
A Study to Evaluate the Safety, Biodistribution, Internal Radiation Dosimetry, and Effective Dose of DaTSCAN™ Ioflupane (123I) Injection in Chinese Healthy Volunteers.
This is a phase 1, single-centre, single-group, nonrandomized, noncomparative, open-label, single-dose study to evaluate the safety, biodistribution, internal radiation dosimetry, and effective dose of DaTSCAN™ ioflupane (123I)…
- Trial name
- NCT04564092
- Testing
- DaTSCAN™ Ioflupane (123I) Injection
- Where
- China
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- GE Healthcare