Clinical trials: Bupivacaine
Cataract
Effect of Warm Bupivacaine on Subtenon Block.
Sub-Tenon's anesthesia is now widely regarded as a preferred local anesthetic method for cataract surgery. Various techniques have been explored to prolong the duration, shorten onset time and improve the efficacy of local…
- Trial name
- NCT07085481
- Testing
- room temperature Bupivacaine, warm Bupivacaine
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Mansoura University
Cesarean Section Wound
Bilevel Erector Spinae Plane Block Versus Transversus Abdominis Plane Block for Analgesia After Cesarean Delivery.
Optimizing analgesia after cesarian delivery is an essential element of enhancing maternal recovery.A multimodal analgesic approach incorporating truncal blocks can provide effective pain relief with minimal side effects for both…
- Trial name
- NCT07137208
- Testing
- ESP block, TAP Block, Bupivacaine injection
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Mansoura University
ACL, Anterior Cruciate Ligament Injuries
Genicular Nerve Blocks for Anterior Cruciate Ligament Knee Surgery
The purpose of this randomized controlled trial is to assess a new analgesia regimen that includes the addition of genicular never blocks to our current standard regimen of peripheral nerve blocks, which includes an adductor…
- Trial name
- NCT05720949
- Testing
- Genicular Nerve Block with bupivacaine and preservative free dexamethasone
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- Hospital for Special Surgery, New York
Anesthesia, Spinal, Hip Fractures
Haemodynamic Effects and Complications of Continuous Versus Single-shot Spinal Anaesthesia for HIP Fracture Surgery
This research project aims to identify a safer method of spinal anaesthesia for elderly patients undergoing surgical stabilisation of proximal femoral fractures.
- Trial name
- CHIPS (NCT07358299)
- Testing
- Bupivacaine Spinal 0,5% Heavy - bolus, Bupivacaine Spinal 0,5% Heavy - titration
- Where
- 2 sites in Poland
- Volunteers
- 216 people
- Sponsor
- Centre of Postgraduate Medical Education
Total Knee Arthroplasty, Regional Anesthesia
Effects of 10 Versus 20 mL Local Anesthetic for Popliteal Plexus Block on Opioid Consumption, Pain, and Patient-Reported Outcomes After Total Knee Arthroplasty
This trial aims to assess the analgesic effect of Popliteal Plexus Block (PPB) with 10 mL versus 20 mL of Bupivacain 5 mg/mL, when applied as an adjunct treatment to a multimodal analgesic regimen following primary total knee…
- Conditions
- Total Knee Arthroplasty, Regional Anesthesia, Multimodal Analgesic Approach, Postoperative Opioid-related Complications
- Trial name
- NCT06908837
- Testing
- Bupivacaine
- Where
- Denmark
- Volunteers
- 120 people
- Sponsor
- Regionshospitalet Silkeborg
Post Operative Pain Control
Efficacy of Ultrasound Guided Erector Spinae Plane Block Versus Ultrasound Guided Serratus Anterior Plane Block for Postoperative Pain Control Following Video-assisted Thoracoscopic Surgeries (VATS): Randomized Control Trial
The aim of the study is to compare the analgesic efficacy of Erector spinae plane block versus Serratus anterior plane block in patients undergoing video-assisted thoracoscopic surgeries.
- Trial name
- NCT07360028
- Testing
- Erector Spinae (ESP) Block with Bupivacaine (Marcaine®), Serratus anterior plane block (SAP)
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Osteoarthritis, Knee
Effect of Reparel Knee Sleeve With Knee Injection
The goals of treating knee osteoarthritis (OA) is to improve or maintain quality of life, mobility and function, pain relief, and improve inflammation.
- Trial name
- NCT04859764
- Testing
- Reparel knee sleeve, Corticosteroid injection
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Alabama at Birmingham
Thoracic Surgery, Video-Assisted
Erector Spinae Plane (ESP) Block vs Intravenous Lignocaine Infusion in (VATS)
The goal of this clinical trial is to compare analgesic efficacy of erector spinae plane (ESP) block vs intravenous lignocaine infusion in video- assisted thoracoscopy (VATS.
- Trial name
- NCT06289790
- Testing
- Erector Spinae Plane (ESP) block, Lignocaine, Bupivacaine
- Where
- Poland
- Volunteers
- 61 people
- Sponsor
- Central Clinical Hospital of the Ministry of Internal Affairs and Administration, Warsaw, Poland
Postoperative Pain Relief
Dexmedetomidine vs Ketamine as Adjuvants to Bupivacaine in Transversus Abdominus Plane Block in Inguinal Hernioplasty
This clinical trial aims to compare the effect of adding dexmedetomidine versus ketamine to bupivacaine in transversus abdominis plane block in patients undergoing unilateral inguinal hernioplasty.
- Trial name
- DEX\KET in TAP (NCT07194694)
- Testing
- Dexmedetomidine & Bupivacaine., ketamine and bupivacaine injection, Bupivacaine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Post Operative Pain
Post Operative Infusion Pump Pain Study
This study will be a pragmatic, prospective cluster randomized trial, where clusters will formed based on sequential 2 week time increments across the study recruitment period..
- Trial name
- NCT07349810
- Testing
- Bupivacaine 0.5% Injectable Solution, Ropivacaine 0.2% Injectable Solution, 1.3% liposomal bupivacaine (Exparel)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Rutgers, The State University of New Jersey
Postherpetic Neuralgia
Ultrasound-Guided Thoracic Paravertebral Block With Steroid and Local Anesthetic for Acute Herpes Zoster: Effects on Pain Control and Prevention of Postherpetic Neuralgia
Background: Acute herpes zoster causes severe neuropathic pain and may progress to postherpetic neuralgia (PHN). This study aims to evaluate ultrasound-guided thoracic paravertebral block with local anesthetic and steroid in…
- Trial name
- NCT07349680
- Testing
- Valacyclovir + Paracetamol (Acetaminophen) + Gabapentin (standard medical therapy), Ultrasound-guided thoracic paravertebral block (TPVB) with bupivacaine 0.25% + methylprednisolone 40 mg
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Analgesia
Comparing the Efficacy of Ultrasound Guided Erector Spinae Plane Block, Ultrasound Guided Caudal Block, and Local Infiltration for Postoperative Pain Control in Pediatric Patients Undergoing Unilateral Inguinal Hernia Repair as a Day-Case Surgeries: A Randomized Controlled Trial
The aim of this study is to evaluate the efficacy of ultrasound guided Erector block versus caudal block versus local wound infiltration perioperatively according to: Primary outcome: to assess and compare the postoperative…
- Trial name
- ECLU (NCT06849804)
- Testing
- Erector Spinae (ESP) Block with Bupivacaine (Marcaine®), Caudal Block Anesthesia, Local infiltration in the wound
- Where
- Egypt
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Tanta University
Kidney Transplant
Erector Spınae Plane Block and Transmuscular Quadratus Lumborum Block In Kıdney Transplantatıon
Perioperative anesthesia and pain management are among the difficult situations for anesthesiologists to manage in kidney transplant patients.
- Trial name
- NCT07059455
- Testing
- Erector Spinae (ESP) Block with Bupivacaine (Marcaine®), Quadratus Lumborum (QL) Block
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kocaeli Derince Education and Research Hospital
Rotator Cuff Injuries, Adhesions
Safety and Efficacy of Platelet-Rich Plasma Combined With Compound Betamethasone in Arthroscopic Surgery for Rotator Cuff Injury With Shoulder Adhesion: A Prospective, Multicenter, Randomized Controlled Trial
Background: Patients undergoing arthroscopic surgery for rotator cuff tears with shoulder adhesion often experience significant postoperative pain and stiffness.
- Trial name
- PRP+CB for RC (NCT07348016)
- Testing
- Liposomal Bupivacaine + Compound Betamethasone Injection, Compound Betamethasone Injection
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Second Affiliated Hospital of Nanchang University
Vocal Cord Disease, Vocal Cord Polyp
Effect of Superior Laryngeal Nerve Blocks on Patient Outcomes in Laryngeal Surgery
Patients undergoing surgery on their vocal cord will either receive a numbing injection to their throat or a saline injection during surgery.
- Conditions
- Vocal Cord Disease, Vocal Cord Polyp, Vocal Cord Cyst
- Trial name
- NCT06734975
- Testing
- Superior laryngeal nerve block - Intervention (Bupivacaine and triamcinolone acetonide suspension)
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Rutgers, The State University of New Jersey
Cesarean Delivery, Spinal Anesthesia for Cesarean Section
Hemodynamics During Cesarean Delivery Under Spinal Anesthesia With Norepinephrine Versus Ephedrine
Echocardiography will be used to measure cardiac output and calculate other important hemodynamic variables in healthy patients with full-term singleton pregnancy during cesarean delivery under conventional spinal anesthesia…
- Trial name
- NCT07322419
- Testing
- Spinal Anesthesia with Bupivacaine and Fentanyl, Crystalloid Coload 1000 mL, Cesarean Delivery
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Mansoura University
Sacral Erector Block Versus Pericapsular Block Versus Lumber Plexus Block
The Analgesic Effect of Ultrasound-guided Sacral Erector Spinae, Pericapsular Nerve Block and Lumber Plexus Block for Pain Relief for Hip Surgery: Randomized Controlled Study
The aim of this study to evaluate the effect of The analgesic effect of Ultrasound-guided Sacral erector spinae, Pericapsular nerve block and Lumber Plexus block for pain relief after hip surgery.
- Trial name
- NCT06842342
- Testing
- Lumber plexus block, Erector Spinae (ESP) Block with Bupivacaine (Marcaine®), PENG Block
- Where
- Egypt
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Tanta University
Pain, Postoperative
Exparel Injection for Postoperative Orbital Pain
After surgery to remove the eye, either by enucleation or evisceration, patients have variable levels of pain for several postoperative days.
- Trial name
- NCT02381353
- Testing
- Bupivacaine
- Where
- 2 sites in United States
- Volunteers
- 88 people
- Sponsor
- Mayo Clinic
Analgesia
Compared With Different Method for Postcesarean Section Analgesia
The aim of this study is compare the efficacy of local anesthetic infiltration into all layers of the anterior abdominal wall and peritoneal instillation and intrathecal injection of morphine with local anesthesic to reduce pain…
- Trial name
- NCT05405049
- Testing
- Morphine hydrochloride, Bupivacain
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Ataturk University
Labour Analgesia
Spinal Analgesia in Labour Pain
To evaluate the efficacy and safety of dexmedetomidine as an adjuvant to bupivacain and fentanyl in spinal Analgesia to decreases pain during normal labour
- Trial name
- NCT07332130
- Testing
- injecting dexmedetomidine, injecting mixture of bupivacaine fentanyl
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Minia University Hospital