Clinical trials: CPAP, completed
Sleep Apnea, Obstructive
Effectiveness of Auto-adjusted Continuous Positive Airway Pressure for Long-term Treatment of Sleep Apnea
Hypothesis: Computer controlled continuous positive airway pressure (autoCPAP) is equally effective in improving obstructive sleep apnea syndrome symptoms, breathing disturbances, objective vigilance, and it is cost-effective…
- Trial name
- NCT00280800
- Testing
- constant CPAP devices, automatic CPAP devices
- Where
- Switzerland
- Volunteers
- 208 people
- Sponsor
- Konrad E. Bloch
Respiratory Distress Syndrome
Comparative Effectiveness Study of Bubble CPAP Devices in the NICU
Multiple different devices are available to provide Bubble CPAP to preterm and newborn infants. The most significant difference between these devices is the size of the bubble produced by the exhalation limb.
- Trial name
- NCT02392806
- Testing
- Bubble CPAP- BabiPlus, Respiralogics, Bubble CPAP- B&B Bubbler, B&B Medical devices
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Marya Strand, MD
OSA
Continuous Positive Airway Pressure Use in Asthma With Moderate to Severe Obstructive Sleep Apnea Patients
Obstructive sleep apnea syndrome (OSAS) and asthma are both common disorders in Hong Kong, with prevalence of at least 4% among the middle-aged male Hong Kong (HK) Chinese populations and 7.2% in young adults respectively.
- Trial name
- OSA (NCT01383564)
- Testing
- CPAP group, non CPAP group
- Where
- China
- Volunteers
- 101 people
- Sponsor
- Chinese University of Hong Kong
Respiratory Distress Syndrome, Hyaline Membrane Disease
Efficacy of a New Technique -"IN-REC-SUR-E"- in Preterm Neonates With RDS
The primary hypothesis of this study is reduction in need of mechanical ventilation in the first 72 hours of life (excluding the transient tracheal intubation performed for surfactant administration and the mechanical ventilation…
- Trial name
- NCT02482766
- Testing
- Poractant alfa, 200 mg/kg, Ventilator for High-frequency Oscillatory Ventilation (HFOV), Nasal Continuous Positive Airway Pressure (nCPAP)
- Where
- 33 sites in Italy
- Volunteers
- 206 people
- Sponsor
- Catholic University of the Sacred Heart
COPD, COPD Exacerbation
The Effect of Stress Ball on COPD Patients Receiving Noninvasive Mechanical Ventilation Support
The aim of this randomised controlled trial was to investigate the effect of a stress ball on pain, anxiety and physiological parameters in Chronic Obstructive Pulmonary Disease (COPD) patients on non-invasive mechanical…
- Trial name
- NCT06461169
- Testing
- stress ball
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Kafkas University
Extreme Prematurity, Respiratory Distress Syndrome
LISA in the Delivery Room for Extremely Preterm Infants
The purpose of this study is to evaluate the effect of LISA used in the delivery room (DR) in decreasing the intubation rates in preterm infants at 22-25 weeks gestational age (GA), during first 72 hours compared to the standard…
- Trial name
- DRLISA (NCT04715373)
- Testing
- LISA
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Texas Southwestern Medical Center
Obstructive Sleep Apnea
Upper Airway Stimulation Versus Continuous Positive Airway Pressure
Standard therapy in patients with obstructive sleep apnea (OSA) is continuous positive airway pressure (CPAP). 30% to 50% are not adherent to this therapy and need an alternative treatment.
- Trial name
- NCT03756805
- Testing
- upper airway stimulation, continuous positive airway pressure
- Where
- Germany
- Volunteers
- 227 people
- Sponsor
- Technical University of Munich
COVID-19 Pneumonia
High Velocity Nasal Insufflation Versus Continuous Positive Airway Pressure in COVID 19 Pneumonic Patients
compare the efficacy of High-Velocity Nasal Insufflation (HVNI) versus Continuous Positive Airway Pressure (CPAP) in managing COVID 19 pneumonic patients with acute type 1 respiratory failure
- Trial name
- NCT07213518
- Testing
- High Velocity Nasal Insufflation, Continuous Positive Airway Pressure
- Where
- Egypt
- Volunteers
- 108 people
- Sponsor
- Mansoura University
Preterm Birth
Delivery Room Practice Change Following the Initiation of the NICHD SUPPORT Trial
This study was designed to analyze whether initiation of the NICHD Neonatal Research Network SUPPORT trial was followed by a change in frequency of endotracheal intubation the delivery room in non-participants and whether these…
- Trial name
- NCT01601886
- Where
- United States
- Volunteers
- 3,843 people
- Sponsor
- Luc Brion
Neonatal Respiratory Distress Syndrome
Heated, Humidified High-flow Nasal (HHHFN) Cannula vs Nasal Continuous Positive Airway Pressure in Respiratory Distress in Premature Neonates
Newborn babies who have difficulty breathing may need breathing support to help them receive enough oxygen. Two commonly used methods are heated, humidified high-flow nasal cannula (HHFNC), which delivers warmed, moist air and…
- Trial name
- NCT07891494
- Testing
- Heated Humidified High-Flow Nasal Cannula therapy, nCPAP
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Pakistan Air Force (PAF) Hospital Islamabad
Chest Trauma
High Flow Nasal Oxygenation Versus Non-invasive Ventilation for Patients With Blunt Chest Trauma
Chest trauma remains an issue for health services for both severe and apparently mild trauma management. Severe chest trauma is associated with high mortality and is liable for 25% of mortality in multiple traumas.
- Trial name
- NCT05342103
- Testing
- high flow oxygenation
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Huda Fahmy Mahmoud, PhD
Obstructive Sleep Apnea
Association Between Treatment Adherence and Treatment Adherence in Sleep Apnea (SEMSAS)
The objective of the study is to define an optimal threshold of the SEMSA-15 scale for obstructive sleep apnea (OSA) perception in patients with OSA to predict 3-month and 1-year continuous positive airway pressure adherence.
- Trial name
- SEMSAS (NCT04894175)
- Where
- France
- Volunteers
- 302 people
- Sponsor
- Thibaut Gentina
Transient Tachypnea
Prophylactic Continuous Positive Airway Pressure (CPAP) in Delivery Room, in the Prevention of Transient Tachypnea of Newborn (TTN): A Randomized Controlled Trial
Transient Tachypnea of the Newborn (TTN) is a disorder of delayed clearance of lung liquid and a common cause of admission of full term infants and late pre term infants (34 to 36 weeks) to Neonatal Intensive Care Units (NICU).
- Trial name
- NCT01082900
- Testing
- Prophylactic CPAP Administration
- Where
- United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- New York Hospital Queens
OSA
Fractional Exhaled Nitric Oxide and CRP Levels in Egyptian Patients With Obstructive Sleep Apnea Syndrome
Obstructive sleep apnea syndrome (OSAS) was associated with upper and lower respiratory tract inflammation, Fractional exhaled nitric oxide (FeNO) proposed as a marker of airway inflammation, few studies were done on the impact…
- Trial name
- NCT04179942
- Testing
- Fractional exhaled nitric oxide and CRP levels
- Where
- Egypt
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Non-Alcoholic Fatty Liver Disease, Obstructive Sleep Apnea
Fatty Liver and Obstructive Sleep Apnea
Non-alcoholic fatty liver disease is associated with obstructive sleep apnea. Abnormalities in liver enzymes can improve following continuous positive airway pressure in patients with obstructive sleep apnea.
- Trial name
- NCT00730873
- Testing
- Continuous positive airway pressure
- Where
- Israel
- Sponsor
- Assaf-Harofeh Medical Center
Type 1 Diabetes, Sleep Apnea Syndrome
Effect of Sleep Apnea Treatment on Type 1 Diabetes
Hypothesis: To address the role of continuous positive airway pressure (CPAP)on nocturnal glycemia in patients having type 1 diabetes and sleep apnea syndrome.
- Trial name
- DIADEME (NCT02316665)
- Testing
- continuous positive airway pressure
- Where
- France
- Volunteers
- 81 people
- Sponsor
- University Hospital, Grenoble
Obstructive Sleep Apnea
TPAP for Comfort in OSA
TheraPAP is a prototype device (with full documented electrical and isolation safety) being developed by SleepRes for the treatment of obstructive sleep apnea (OSA) that can deliver either standard CPAP at a set pressure or what…
- Trial name
- NCT06264128
- Testing
- TPAP, CPAP
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- SleepRes Inc.
Obstructive Sleep Apnea of Adult
Investigation of Predictive Indices to Objectively Guide Choice of CPAP Interface
Obstructive sleep apnea (OSA) is a prevalent disease, and one that is associated with significant negative impact on long-term survival.
- Trial name
- NCT03063567
- Testing
- CPAP interfaces
- Volunteers
- 100 people
- Sponsor
- Singapore General Hospital
Obstructive Sleep Apnea
Impact of Telemonitoring to Improve Adherence in Continuous Positive Airway Pressure (CPAP)-Treated Patients
Improvement in CPAP adherence can be obtained by usingTelemonitoring. T4P® is a telemonitoring unit added on CPAP device allowing to obtain a daily report of usage duration, mask leaks, pressure and apnea-hypopnea index.
- Trial name
- NCT02773953
- Testing
- T4PTelemonitoring, CPAP
- Where
- Belgium
- Volunteers
- 46 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Obstructive Sleep Apnea, Nasal Congestion
Effect of Heated Humidity With Thermosmart™ Compared to an Intranasal Steroid in Improving Compliance and Nasal Symptoms in Patients Using Continuous Positive Airway Pressure
1. CPAP compliance will be significantly higher in both the heated humidity with Thermosmart™ and the nasal steroid phases compared to the double placebo phase. 2.
- Conditions
- Obstructive Sleep Apnea, Nasal Congestion, Sinus Congestion
- Trial name
- Thermosmart (NCT00665977)
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Clayton Sleep Insititute