Clinical trials: Conventional therapy
Sepsis, Tuberculosis
STeroids and Enhanced Spectrum Antibiotics for the Treatment of Patients in Africa With Refractory Sepsis
Sepsis, a life-threatening condition due to a dysregulated response to infection, is the leading cause of global mortality and is frequently driven by tuberculosis (TB) and drug-resistant bacteria in sub-Saharan Africa…
- Trial name
- STARS (NCT07332325)
- Testing
- Hydrocortisone administration, Expanded antimicrobial therapy
- Where
- 4 sites in Tanzania, Uganda
- Volunteers
- 344 people
- Sponsor
- University of Virginia
Cannabis Use Disorder
Comparing the Spanish Version of CANreduce With or Without Psychological Support and Treatment as Usual, Reducing Cannabis Use.
Cannabis is the most widely used psychoactive substance around the world after alcohol and tobacco. Although approximately one in ten users develop serious problems of dependency, only a small number attend outpatient addiction…
- Trial name
- CANREDUCE (NCT04517474)
- Testing
- CANreduce, psychological support
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- Parc de Salut Mar
Knee Osteoarthristis
Evaluating the Impact of a Meta Quest 3 Gamified VR Rehabilitation Program in Knee Osteoarthritis
The goal of this clinical trial is to learn if a gamified virtual reality (VR) rehabilitation program can effectively reduce pain, improve functionality, and enhance balance in adults aged 40-64 years diagnosed with knee…
- Trial name
- NCT06735963
- Testing
- Meta Quest 3 Virtual Reality, Exercise, Electrotherapy
- Where
- Saudi Arabia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Umm Al-Qura University
Sleep Apnea, Obstructive
Comparison Study of the ICON™ Auto Series With and Without SensAwake™ and ThermoSmart™ and Conventional Continuous Positive Airway Pressure in Obstructive Sleep Apnea Patients
A total of 216 patients will be randomized into a partially single blind, randomized, parallel-arm trial to determine whether the ICON™ AT with SensAwake™ and ThermoSmart™ can improve therapy adherence when compared to standard…
- Trial name
- NCT01517763
- Testing
- Conventional CPAP Therapy, Fixed pressure ICON™ without ThermoSmart™, Auto ICON™ with SensAwake™ and ThermoSmart™
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Fisher and Paykel Healthcare
Patellofemoral Pain Syndrome
Effects of Kinesiotaping and Mulligan Tapping on PFPS
The aim of this research is to compare the effects of kinesiotaping and mulligan taping on pain, hamstring flexibility, cadence and physical performance of lower limb in patients suffering from patellofemoral pain syndrome…
- Trial name
- NCT05125263
- Testing
- kinesiotaping group, mulligan taping group
- Where
- Pakistan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Colorectal Cancer, Gastrointestinal Complications
J-Pouch Colorectal Anastomosis or Straight Colorectal Anastomosis in Treating Patients With Rectal Cancer Who Have Undergone Surgery to Remove the Tumor
RATIONALE: It is not yet known whether a J-pouch colorectal anastomosis is more effective than a straight colorectal anastomosis in treating patients with rectal cancer who have undergone surgery to remove the tumor.
- Conditions
- Colorectal Cancer, Gastrointestinal Complications, Perioperative/Postoperative Complications
- Trial name
- NCT01110798
- Testing
- intraoperative complication management/prevention, assessment of therapy complications, gastrointestinal complications management/prevention
- Where
- 4 sites in Italy
- Volunteers
- 600 people
- Sponsor
- Azienda Ospedaliera di Padova
Neuroblastoma, Neuroblastoma Recurrent
Anti-GD2 CAR T Cells in Pediatric Patients Affected by High Risk and/or Relapsed/Refractory Neuroblastoma or Other GD2-positive Solid Tumors
The purpose of this study is to test the safety and efficacy of GD2-CART01, a CAR T cell treatment targeting GD2 in paediatric or young adult patients with High Risk and/or relapsed/refractory Neuroblastoma.
- Conditions
- Neuroblastoma, Neuroblastoma Recurrent, GD2-positive Solid Tumors, Osteosarcoma
- Trial name
- NCT03373097
- Testing
- GD2-CART01
- Where
- Italy
- Volunteers
- 42 people
- Sponsor
- Bambino Gesù Hospital and Research Institute
Afebrile Seizure (Finding)
Toxicological Screening by GC-MS Among Children Admitted for a First Afebrile Seizure
Before the age of 14 years, 1% of the paediatric population will develop a seizure. The only systematically required complementary examination is an electroencephalogram (EEG).
- Trial name
- CASTox (NCT03310697)
- Testing
- Collection of blood and urine samples, Clinical examination
- Where
- France
- Volunteers
- 48 people
- Sponsor
- University Hospital, Toulouse
Stroke, Chronic Stroke
Effects of Different Doses of Virtual Reality Therapy in Chronic Stroke Patients
This study aimed to compare the effects of different doses of Wii Fit-based virtual reality (VR) therapy added to conventional rehabilitation in patients with chronic stroke.
- Trial name
- NCT07656987
- Testing
- Wii Fit-Based Virtual Reality Balance Training, Conventional Physiotherapy and Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Rheumatoid Arthritis, Atherosclerosis
Effect of Sarilumab on Atherosclerotic Disease Assessed by PET/CET in Patients With RA (SARIPET)
Rheumatoid arthritis (RA) is a condition associated with a high incidence of cardiovascular disease (CV), primarily as a result of accelerated atherosclerosis .
- Trial name
- SARIPET (NCT04350216)
- Testing
- Sarilumab 200 MG/1.14 ML Subcutaneous Solution [KEVZARA]
- Volunteers
- 20 people
- Sponsor
- Instituto de Investigación Marqués de Valdecilla
Sarcoma
Trastuzumab in Treating Patients With Recurrent Osteosarcoma
RATIONALE: Monoclonal antibodies, such as trastuzumab, can locate tumor cells and either kill them or deliver tumor-killing substances to them without harming normal cells.
- Trial name
- NCT00005033
- Testing
- trastuzumab, conventional surgery
- Where
- 4 sites in United States
- Sponsor
- Memorial Sloan Kettering Cancer Center
Spinal Cord Injuries
Benefits of Applying Neuroprosthesis to Improve Grasping and Reaching in Spinal Cord Injury Patients
Functional electrical stimulation is a process that uses low intensity electrical pulses generated by an electric stimulator to create muscle contractions.
- Trial name
- NCT00221117
- Testing
- Neuroprosthesis-FES Therapy, Conventional Ocupational Therapy (COT)
- Volunteers
- 22 people
- Sponsor
- Toronto Rehabilitation Institute
Cervical Cancer
Chemotherapy Followed By Surgery Vs Radiotherapy Plus Chemotherapy in Patients With Stage IB or II Cervical Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Giving chemotherapy drugs before surgery may shrink the tumor so that it can be removed during surgery.
- Trial name
- NCT00039338
- Testing
- conventional surgery, neoadjuvant chemotherapy, brachytherapy
- Where
- 24 sites in Austria, Belgium and 6 more
- Volunteers
- 686 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Frailty Syndrome, Prefrail Elderly
Comparıson of the Effıcacy of Conventıonal Exercıse and Pılates ın Pre-fraıl and Fraıl Older Adults
Brief Summary This clinical study aims to compare the effects of a conventional exercise program and a Pilates exercise program in prefrail and frail older adults.
- Conditions
- Frailty Syndrome, Prefrail Elderly, Frail Elderly, Geriatric
- Trial name
- NCT07458048
- Testing
- PILATES EXERCISES GROUP, CONVENTIONAL EXERCISES GROUP
- Volunteers
- 40 people
- Sponsor
- Istanbul University - Cerrahpasa
Chronic Neck Pain
Comparative Effectiveness and Cost-effectiveness of Chuna Manual Therapy for Chronic Neck Pain
A multi-center randomized controlled trial assessing the comparative effectiveness and cost-effectiveness of Chuna manual therapy for chronic neck pain
- Trial name
- NCT03294785
- Testing
- Chuna manual therapy, Conventional medication, Physical therapy
- Where
- 5 sites in South Korea
- Volunteers
- 108 people
- Sponsor
- Jaseng Medical Foundation
End-Stage Kidney Disease (ESKD), Chronic Kidney Disease (CKD)
Comparing Hemodiafiltration to Conventional Hemodialysis: Effects on Clinical and Biochemical Parameters
Chronic kidney disease may progress to end-stage renal disease, a stage in which the kidneys will no longer be able to adequately remove extra fluid and waste products from the body.
- Trial name
- NCT07662889
- Testing
- Conventional Hemodialysis, Hemodiafiltration
- Where
- Pakistan
- Volunteers
- 64 people
- Sponsor
- Services Institute of Medical Sciences, Pakistan
Stroke
"Evaluation Of ALBA® Device for Upper Extremity Motor Function In Adults With Subacute And Chronic Acquired Brain Injury"
As part of the rehabilitation techniques, robotic equipment has been introduced for the rehabilitation of the upper extremity with promising results.
- Trial name
- NCT05824416
- Testing
- Experimental: ALBA, Conventional Therapy
- Where
- Chile
- Volunteers
- 32 people
- Sponsor
- uMov
Low Back Pain, Low Back Dysfunction
EFFICACY OF ARTIFICIAL INTELLIGENCE DRIVEN PROGRAM VERSUS TRADITIONAL PHYSICAL THERAPY PROGRAM IN PATIENTS WITH LOW BACK DYSFUNCTION
Low back dysfunction is one of the most common musculoskeletal disorders and is associated with pain, disability, and reduced quality of life.
- Trial name
- AI-LBD (NCT07749833)
- Testing
- AI-Driven Rehabilitation Program, Traditional Physical Therapy Program
- Where
- Egypt
- Volunteers
- 68 people
- Sponsor
- Cairo University
Cerebral Palsy
Constraint-induced Movement Therapy and Self-regulation for Children With Cerebral Palsy
This study examines the effect of combining modified constraint-induced movement therapy (mCIMT) and self-regulation (SR) in promoting upper limb function of children with hemiplegic cerebral palsy (CP) studying in a school-based…
- Trial name
- NCT02957708
- Testing
- mCIMT + SR, Control
- Where
- Hong Kong
- Volunteers
- 10 people
- Sponsor
- University of Western Sydney
Lateral Epicondylitis
Physiotherapy Applications in Lateral Epicondylitis
This study aims to compare the effectiveness of extracorporeal shock wave therapy (ESWT) and high-intensity laser therapy (HILT) in improving pain, grip strength, and function in patients with lateral epicondylitis.
- Trial name
- NCT07028840
- Testing
- Physiotherapy, Extracorporeal Shock Wave Therapy (ESWT), High-Intensity Laser Therapy (HILT)
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Pamukkale University
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