Clinical trials: Echocardiography
Diastolic Dysfunction, Septic Shock
Reversibility of Diastolic Disfunction in Septic Shock
Objectives: To study the prognostic value of the evolution of diastolic function according to fluid balance in patients admitted to the ICU with a diagnosis of septic shock, in terms of mortality (ICU and hospital) and mortality…
- Trial name
- REPRISS (NCT03198611)
- Testing
- Echocardiography
- Where
- 5 sites in Spain
- Volunteers
- 350 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Aortic Valve Insufficiency, Aortic Stenosis
Three Dimensional Imaging and Wireless Technologies to Enhance Medical Care in Space
NASA has outlined the most urgent threats to life and health in manned spaceflight. One of the threats is the risk of trauma and acute medical problems.
- Trial name
- NCT00598767
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- The Cleveland Clinic
Lupus Nephritis, Diastolic Dysfunction
Diastolic Dysfunction and Inflammatory Biomarkers in Lupus Nephritis
This cross-sectional observational study aims to investigate the correlation between echocardiographic parameters of left ventricular diastolic dysfunction (E/A ratio, e', E/e' ratio, LAVI, and LVEF) and systemic inflammatory…
- Conditions
- Lupus Nephritis, Diastolic Dysfunction, Systemic Lupus Erythematosus, Heart Failure, Diastolic
- Trial name
- NCT07837544
- Volunteers
- 90 people
- Sponsor
- Assiut University
Congenital Heart Disease, Atherosclerosis
Cardiovascular Disease Screening
This study will evaluate volunteers 18 years of age and older to see if they qualify for one of NHLBI s research studies. Tests include the following: General medical evaluation, which may include blood tests, chest x-ray…
- Conditions
- Congenital Heart Disease, Atherosclerosis, Myocardial Ischemia, Myocardial Infarction
- Trial name
- NCT00483951
- Testing
- Toshiba Aquilion ONE CT, SWiemens MRI scanner
- Where
- 2 sites in United States
- Volunteers
- 1,325 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Syncope
Point-of-Care Ultrasound in the Emergency Department Evaluation of Syncope
The purpose of this study is to determine whether point-of-care (bedside) ultrasound assists physicians in the evaluation and management of patients with syncope.
- Trial name
- NCT01671371
- Testing
- Point-of-Care Ultrasound
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Yale University
Cardiac Allograft Vasculopathy
Microvascular Cardiac Allograft Vasculopathy Trial
The aim of the mCAV study is a comprehensive characterization of the genetic, morphological and functional phenotype of isolated microvascular graft vasculopathy (mCAV) after orthotopic heart transplantation (OHT).
- Trial name
- mCAV (NCT05826444)
- Testing
- Echocardiography, Magnetic resonance imaging, Magnetocardiography
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- German Heart Institute
Pulmonary Hypertension
Outpatient Vasodilator Assessment Using Iloprost in Pulmonary Hypertension
This study will compare the clinical efficacy of inhaled iloprost as an invasive, selective vasodilator in the cardiac catheterization laboratory in patients with pulmonary hypertension to the gold standard of inhaled nitric…
- Trial name
- OVATION (NCT03044314)
- Testing
- Iloprost and nitric oxide administration
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Duke University
Cardiac Output, Low
Real-time Continuous Cardiac Output Measurements
Study to assess the feasibility of real-time automatic cardiac output measurements using transthoracic echocardiography (TTE)
- Trial name
- NCT04774978
- Testing
- TTE
- Volunteers
- 20 people
- Sponsor
- Rijnstate Hospital
Locally Advanced Lung Non-Small Cell Carcinoma, Stage III Lung Cancer AJCC v8
Cardiovascular Injury and Cardiac Fitness in Locally Advanced Non-Small Cell Lung Cancer Patients Receiving Model Based Personalized Chemoradiation
This study assesses cardiovascular injury and cardiac fitness in patients with non-small cell lung cancer that has spread to nearby tissue or lymph nodes (locally advanced) receiving model based personalized chemoradiation.
- Conditions
- Locally Advanced Lung Non-Small Cell Carcinoma, Stage III Lung Cancer AJCC v8, Stage IIIA Lung Cancer AJCC v8, Stage IIIB Lung Cancer AJCC v8
- Trial name
- NCT05010109
- Testing
- 6 Minute Walk Functional Test, Biospecimen Collection, Computed Tomography
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- M.D. Anderson Cancer Center
Mitral Valve Insufficiency, Atrial Fibrillation
Left Atrial Distensibility to Predict Left Ventricular Filling Pressure and Prognosis in Patients With Severe Mitral Regurgitation
A large left atrial (LA) volume, which represents chronic diastolic dysfunction, is associated with a poor outcome, regardless of systolic function.
- Conditions
- Mitral Valve Insufficiency, Atrial Fibrillation, Heart Failure
- Trial name
- NCT01172184
- Testing
- Cardiac catheterization
- Where
- Taiwan
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Veterans General Hospital.
Diagnostic Imaging, Myocardial Ischemia
Sonazoid in Myocardial Perfusion Imaging
Currently, Sonazoid is mainly used for imaging liver lesions by assessing perfusion characteristics. However, the ultrasound technology is the same as for cardiac imaging and the stability of the microbubbles will potentially aid…
- Trial name
- (SIMPI) (NCT05637333)
- Testing
- Contrast Stress Echocardiography
- Where
- United Kingdom
- Sponsor
- London North West Healthcare NHS Trust
Heart Failure, Diastolic Dysfunction
Diastology-Guided Management of Decompensated Heart Failure
More than 30% of people hospitalized with decompensated heart failure return to the hospital within 90 days. Emerging evidence suggests that hemodynamic monitoring with guided management may enhance prognosis and management.
- Trial name
- DYNAMIC (NCT06131008)
- Testing
- Diastology, Diastology-Guided Diuresis, Usual Care
- Volunteers
- 30 people
- Sponsor
- McMaster University
Patent Ductus Arteriosus
Assessment of Therapeutic Effect of Rectal Vs. Intravenous Paracetamol in The Treatment of Patent Ductus Arteriosus (PDA) in Neonates
To compare the effectiveness of rectal vs. intravenous paracetamol in the medical treatment of significant PDA in neonates.
- Trial name
- NCT06256211
- Testing
- Paracetamol
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Soha mahmoud Hussien mahdy
Peritoneal Dialysis, Hypervolemia
Lung Ultrasound in PD Patients
Although many alternative methods are present, maintaining ideal volume status in peritoneal dialysis (PD) patients still rely on clinical evaluation due to lack of an evidence based method.
- Conditions
- Peritoneal Dialysis, Hypervolemia, VEGF Overexpression
- Trial name
- LUSiPD (NCT03801044)
- Testing
- NT-BNP, VEGF, Echocardiography, Chest Radiography
- Where
- Turkey (Türkiye)
- Volunteers
- 23 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Embolic Stroke of Undetermined Source
Embolic Stroke of Undetermined Source, Continuous Electrocardiography and Transthoracic ECHOcardiography in Hospitalized Patients With Ischemic Stroke
Transthoracic echocardiography (TTE) is recommended in patients with ischemic stroke when cardiac etiology is suspected to help plan secondary stroke management.
- Trial name
- ESECHO (NCT04808258)
- Testing
- C3+ Holter Monitor
- Where
- 2 sites in Denmark
- Volunteers
- 500 people
- Sponsor
- Herlev and Gentofte Hospital
Ventricular Tachycardia
Catheter Ablation Versus Radio-Ablation for Ventricular Tachycardia: a Randomized Controlled Trial
This study compares two arms - the current standard of care catheter ablation for Ventricular Tachycardia compared to stereotactic radiotherapy to non-invasively ablate ventricular tachycardia using a novel non-invasive ECG based…
- Trial name
- CARA-VT RCT (NCT05047198)
- Testing
- Control - Catheter Ablation for VT, Treatment - Non-Invasive Radio Ablation for VT
- Where
- Canada
- Volunteers
- 244 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Thoracic Tumor
Detection of (Sub)Clinical Toxicity in Irradiated vs. Non-irradiated Surgically Treated Esophageal Cancer Patients: a Pilot Study (CROSS SECT)
Rationale: Radiation-induced cardiac and pulmonary toxicity after treatment for intra-thoracic tumors is a clinically relevant problem, which may jeopardize the benefit of (neo-adjuvant) (chemo) radiotherapy.
- Trial name
- CROSS SECT (NCT03396614)
- Testing
- CTTC scan, cardiac MRI, ECG, 6 minute walking test, echocardiogram
- Where
- Netherlands
- Volunteers
- 40 people
- Sponsor
- University Medical Center Groningen
Left Ventricular Noncompaction, Isolated Noncompaction of the Ventricular Myocardium
Cardiac Computed Tomography: Characteristics of Isolated Left Ventricular Non-compaction
The diagnostic criteria for isolated left ventricular non-compaction cardiomyopathy (IVNC) have been well established for echocardiography and cardiac magnetic resonance, such validation is lacking for computed tomography (CT).
- Trial name
- NCT01470014
- Where
- Switzerland
- Volunteers
- 39 people
- Sponsor
- University of Zurich
Heart Failure, Diastolic
Multimodality Imaging in the Screening, Diagnosis and Risk StratifictiON of HFpEF
The incidence of Heart failure with preserved ejection fraction (HFpEF) in Heart failure patients increases rapidly. However, the current clinical awareness is insufficient, and the cardiac structural and functional injury are…
- Trial name
- NCT04603404
- Where
- China
- Volunteers
- 430 people, healthy volunteers welcome
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Acute Heart Failure
Consultation at 8 Days to Reduce Hospitalisations in Heart Failure Patient
Evaluate the benefit of systematic appointment with a cardiologist a week after hospitalisation for acute heart failure. Randomised, endpoint: number of day alive out of hospital during 6 months
- Trial name
- CHIC (NCT01834833)
- Testing
- Follow-up
- Where
- France
- Volunteers
- 326 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
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