Clinical trials: Etoposide, completed
Childhood Acute Basophilic Leukemia, Childhood Acute Eosinophilic Leukemia
Combination Chemotherapy in Treating Young Patients With Down Syndrome and Acute Myeloid Leukemia or Myelodysplastic Syndromes
This phase III trial is studying how well combination chemotherapy works in treating young patients with Down syndrome and acute myeloid leukemia or myelodysplastic syndromes.
- Conditions
- Childhood Acute Basophilic Leukemia, Childhood Acute Eosinophilic Leukemia, Childhood Acute Erythroleukemia (M6), Childhood Acute Megakaryocytic Leukemia (M7)
- Trial name
- NCT00369317
- Testing
- asparaginase, daunorubicin hydrochloride, cytarabine
- Where
- 97 sites in United States, Australia and 2 more
- Volunteers
- 205 people
- Sponsor
- Children's Oncology Group
Natural Killer/T-Cell Lymphoma, Nasal and Nasal-Type
Tislelizumab Combined Treatment in Refractory Extranodal NK/T-cell Lymphoma
Natural killer/T-cell lymphoma (NKTCL) patients with relapsed/refractory disease had very poor outcome. Anti-PD-1 antibody showed promising results in response, but but the complete remission rate of was low.
- Trial name
- NCT05058755
- Testing
- tislelizumab, azacytidine, lenalidomide, tislelizumab, etoposide, pegaspargase
- Where
- China
- Volunteers
- 62 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Lymphoma
Combination Chemotherapy Plus Peripheral Stem Cell Transplantation With or Without Rituximab in Treating Patients With Relapsed Non-Hodgkin's Lymphoma
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Peripheral stem cell transplantation may allow the doctor to give higher doses of chemotherapy drugs and…
- Trial name
- NCT00005589
- Testing
- filgrastim, rituximab, carmustine
- Where
- 131 sites in Australia, Austria and 15 more
- Volunteers
- 460 people
- Sponsor
- EBMT Solid Tumors Working Party
Lymphoma
Chemotherapy and Radiation Therapy Followed by Peripheral Stem Cell Transplantation in Treating Patients With Non-Hodgkin's Lymphoma
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage cancer cells.
- Trial name
- NCT00002510
- Testing
- filgrastim, cyclophosphamide, etoposide
- Where
- United States
- Sponsor
- Temple University
Localized High-risk Soft Tissue Sarcomas of the Extremities and Trunk Wall in Adults
Localized High-Risk Soft Tissue Sarcomas Of The Extremities And Trunk Wall In Adults: An Integrating Approach Comprising Standard Vs Histotype-Tailored Neoadjuvant Chemotherapy
This is a randomized Phase III clinical trial in the setting of localized high-risk soft tissue sarcomas (STS). This study will compare a standard neoadjuvant chemotherapy with epirubicin plus ifosfamide versus a histology-driven…
- Trial name
- NCT01710176
- Testing
- epirubicin 60 mg/m2/day (days 1, 2) and ifosfamide 3 g/m2/day (days 1, 2, 3), gemcitabine 900 mg/m2 (days 1 and 8) and docetaxel 75 mg/m2 (day 8), trabectedin 1.3 mg/m2
- Where
- 15 sites in Italy, Spain
- Volunteers
- 550 people
- Sponsor
- Italian Sarcoma Group
Large B-Cell Diffuse Lymphoma
Oral Azacitidine Plus Salvage Chemotherapy in Relapsed/Refractory Diffuse Large B Cell Lymphoma
The purpose of this study is to determine the safety and tolerability of adding oral azacitidine to the chemotherapy combination R-ICE. This study will also look at whether or not disease outcomes improve with the combination.
- Trial name
- NCT03450343
- Testing
- Oral azacitidine, R-ICE
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Medical University of South Carolina
Lymphoblastic Lymphoma
NHL16: Study For Newly Diagnosed Patients With Acute Lymphoblastic Lymphoma
This is a phase II clinical trial using risk-adapted therapy. The treatment is acute lymphoblastic leukemia (ALL)-based therapy, using multi-agent regimens comprising of induction, consolidation, and continuation (maintenance)…
- Trial name
- NCT01451515
- Testing
- Prednisone, Vincristine, Daunorubicin
- Where
- 2 sites in United States
- Volunteers
- 23 people
- Sponsor
- St. Jude Children's Research Hospital
Lung Cancer
S0124: Cisplatin Combined With Irinotecan or Etoposide For Extensive-Stage Small Cell Lung Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.
- Trial name
- NCT00045162
- Testing
- cisplatin, etoposide, irinotecan hydrochloride
- Where
- 408 sites in United States, Canada
- Volunteers
- 671 people
- Sponsor
- SWOG Cancer Research Network
Refractory Hematologic Cancer, Allogeneic Stem Cell Transplantation
CLAGE Sequential With Flu-Bu Conditioning for Refractory Acute Leukemia
For patients with refractory acute leukemia, allogeneic stem cell transplantation is the only curative therapy. Only 20% of patients may achieve long-term survival mostly due to relapse or nor-relapse mortality (NRM).
- Trial name
- NCT03882203
- Testing
- CLAGE-FluBu
- Where
- China
- Volunteers
- 18 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Diffuse Large B Cell Lymphoma
FDG-PET-Stratified R-DICEP and R-Beam/ASCT For Diffuse Large B-Cell Lymphoma
The purpose of this study is to evaluate: 1. whether an imaging test called a PET (Positron emission tomography) scan performed after two cycles of standard chemotherapy is able to identify patients who have a high cure rate…
- Trial name
- PET-Chop (NCT00530179)
- Testing
- Autologous Blood Stem Transplantation, R-CHOP
- Where
- 3 sites in Canada
- Volunteers
- 69 people
- Sponsor
- AHS Cancer Control Alberta
Lung Cancer
Combination Chemotherapy in Treating Patients With Small Cell Lung Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.
- Trial name
- NCT00004186
- Testing
- carboplatin, etoposide, ifosfamide
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- University of Alabama at Birmingham
Lung Cancer
Radiation Therapy Plus Chemotherapy in Treating Patients With Non-small Cell Lung Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug and combining chemotherapy with radiation therapy may kill more tumor cells.
- Trial name
- NCT01134861
- Testing
- cisplatin, Etoposide, Vinblastine
- Volunteers
- 610 people
- Sponsor
- Radiation Therapy Oncology Group
Solid Tumors, Relapsed/Refractory Sarcomas
Clinical Study of Vorinostat in Combination With Etoposide in Pediatric Patients < 21 Years at Diagnosis With Refractory Solid Tumors
The purpose of this study is to find out how safe and effective treatment with a new combination of drugs, vorinostat and etoposide, is in treating cancer.
- Trial name
- NCT01294670
- Testing
- Vorinostat and Etoposide
- Where
- 11 sites in United States, Canada
- Volunteers
- 27 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Recurrent Classic Hodgkin Lymphoma, Refractory Classic Hodgkin Lymphoma
Combination Chemotherapy With or Without Bortezomib in Treating Patients With Classical Hodgkin Lymphoma That Has Returned or Does Not Respond to Prior Treatment.
This phase II trial studies how well combination chemotherapy with or without bortezomib works in treating patients with classical Hodgkin lymphoma that has come back or does not respond to prior treatment.
- Trial name
- NCT00967369
- Testing
- Bortezomib, Carboplatin, Etoposide
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- M.D. Anderson Cancer Center
Lymphoma
Combination Chemotherapy in Treating Patients With AIDS-Related Lymphoma
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells.
- Trial name
- NCT00002524
- Testing
- Bleomycin Sulfate, Filgrastim, Cisplatin
- Where
- 2 sites in United States
- Volunteers
- 46 people
- Sponsor
- M.D. Anderson Cancer Center
Breast Cancer
Apatinib Combined With Oral Etoposide in Metastatic HER2 Negative Breast Cancer
The hypothesis of this study is to discover if the all-oral therapy with apatinib plus oral Etoposide can shrink or slow the growth of pretreated HER2 negative metastatic breast cancer.
- Trial name
- NCT03535961
- Testing
- apatinib+oral etoposide
- Where
- China
- Volunteers
- 32 people
- Sponsor
- Chinese Academy of Medical Sciences
Small Cell Lung Carcinoma, Extensive Disease
Randomized Study of Cisplatin-Etoposide Versus an Etoposide Regimen Without Cisplatin in Extensive Small-Cell Lung Cancer
The purpose of this study is to determine if a cisplatin-etoposide regimen improves survival in comparison to a regimen containing etoposide and without platinum derivative.
- Trial name
- NCT00658580
- Testing
- Cisplatin + etoposide, Epirubicin + ifosfamide + etoposide
- Where
- 4 sites in Belgium, France and 2 more
- Volunteers
- 361 people
- Sponsor
- European Lung Cancer Working Party
Neoplasms, Unknown Primary
Gemcitabine/Irinotecan/ZD1839 vs Paclitaxel/Carboplatin/Etoposide/ZD1839 in Carcinoma of Unknown Primary Site
In this randomized trial, we will investigate the activity and toxicity of two active regimens, gemcitabine/irinotecan and paclitaxel/carboplatin/Etoposide (both followed by ZD1839) in the first-line treatment of patients with…
- Trial name
- NCT00193596
- Testing
- Etoposide, Gemcitabine, Irinotecan
- Where
- 31 sites in United States
- Volunteers
- 198 people
- Sponsor
- SCRI Development Innovations, LLC
Leukemia, Myelodysplastic Syndromes
Intensive Compared With Nonintensive Chemotherapy in Treating Older Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. It is not yet known if stronger doses of chemotherapy given over a longer period of time are as well…
- Conditions
- Leukemia, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Neoplasms
- Trial name
- NCT00005823
- Testing
- cytarabine, daunorubicin hydrochloride, etoposide
- Where
- 3 sites in United Kingdom
- Volunteers
- 2,000 people
- Sponsor
- Leukemia Research Fund
Multiple Myeloma and Plasma Cell Neoplasm
Peripheral Stem Cell Transplantation Plus Combination Chemotherapy in Treating Patients With Multiple Myeloma
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell transplantation may allow the doctor to give higher doses of…
- Trial name
- NCT00003399
- Testing
- carmustine, cisplatin, cyclophosphamide
- Where
- United States
- Sponsor
- University of Maryland, Baltimore