Clinical trials: Experimental Group
Spinal Cord Injury, Psychosocial Problem
Effects of a Coping-oriented Supportive Programme (COSP) for People With Spinal Cord Injury During Inpatient Rehabilitation
The aim of this proposed PhD study is to test the effectiveness of a newly developed coping-oriented supportive programme (COSP) for Chinese people with SCI during their early period of inpatient rehabilitation in Xi'an, China.
- Trial name
- NCT02672670
- Testing
- Experimental: Intervention group---coping-oriented supportive programme, Active Comparator: Comparison group---a didactic talk (usual care)
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Bupivacaine, Ultrasound-Guided
Bupivacaine Liposomes or Bupivacaine for CMB on Postoperative Analgesia in Laparoscopic Hepatobiliary Pancreatic Surgery
Numerous studies have confirmed that regional analgesia using peripheral nerve block has great potential for perioperative analgesia in abdominal surgery.
- Conditions
- Bupivacaine, Ultrasound-Guided, Analgesia, Postoperative, Opioids
- Trial name
- NCT06737341
- Testing
- Bupivacaine Liposomes(BL), Bupivacaine(B)
- Where
- 2 sites in China
- Volunteers
- 60 people
- Sponsor
- Huazhong University of Science and Technology
Patient Relations, Nurse, Patient Satisfaction
Aromatherapy Methods in Reducing Anxiety Before Breast Biopsy
A breast biopsy is a cause for anxiety for most women when faced with a diagnosis of breast cancer. Physiological and psychological effects of breast biopsy may continue in the pre-biopsy and post-biopsy period.
- Conditions
- Patient Relations, Nurse, Patient Satisfaction, Anxiety State, Breast Cancer
- Trial name
- NCT05276505
- Testing
- Lavender Aromatherapy Tablet
- Where
- Turkey (Türkiye)
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Osteo Arthritis Knee, Knee Osteoarthritis
Knee Arthritis Treatment With Autologous Fragmented Adipose Tissue and PRP - Comparison of Two Treatment Methods
This is a prospective, randomized, controlled study. The purpose of this study is to assess functional and clinical changes among patients with symptomatic knee OA treated with intra-articular injections of autologous adipose…
- Conditions
- Osteo Arthritis Knee, Knee Osteoarthritis, Knee Pain Chronic, Knee Arthritis
- Trial name
- NCT04321629
- Testing
- autologous adipose tissue transfer, PRP injections
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Rehasport Clinic
Psychological Stress, Mental Fatigue
A Multi-Dimensional Comparative Study of Exercise Psychological Experience Under AI Fitness Companion and Human Coach Paradigms
This study conducted a comparative analysis of subjective exercise experiences between an AI-based fitness companion and traditional human coaching among 98 university students participating in a standardized 20-minute functional…
- Conditions
- Psychological Stress, Mental Fatigue, Cognitive Dysfunction, Emotional Well-being
- Trial name
- NCT07690553
- Testing
- AI-Based Companion, Human-Coached
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Lincoln University College
Scoliosis Idiopathic
Effect of Scoliosis-Specific Exercise on Lower Limb Biomechanics
PURPOSE: To examine the effect of Physiotherapeutic Scoliosis-Specific Exercise on limb biomechanical parameters in adolescents with idiopathic scoliosis.
- Trial name
- NCT06266637
- Testing
- Conventional Physical Therapy Program, Physiotherapeutic Scoliosis-Specific Exercise (Schroth)
- Where
- Egypt
- Volunteers
- 56 people
- Sponsor
- Delta University for Science and Technology
Influenza, Influenza Vaccine
Clinical Trial of Quadrivalent Subunit Influenza Vaccine (Adjuvant) in Chinese Population Aged 65 Years and Older
The objective of this study was to evaluate the safety of quadrivalent subunit influenza vaccine (adjuvant) in people aged 65 years and older.
- Trial name
- NCT07421037
- Testing
- Quadrivalent Subunit Influenza Vaccine (Adjuvant), MF59, 0.9% sodium chloride injection (normal saline)
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ab&B Bio-tech Co., Ltd.JS
HIV-1-infection
Modelling the Interaction Between Rationally-designed Synthetic Model Viral Protein Immunogens
The objective of this experimental medicine study is to determine the extent to which different prime-boost combinations influence serum neutralising antibody breadth and associated B and T cells responses.
- Trial name
- EAVI2020_01 (NCT03816137)
- Testing
- ConM SOSIP, EDC ConM SOSIP, ConS UFO
- Where
- United Kingdom
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Signs and Symptoms
Impact of a Probiotic-based Formula on Digestive Symptoms and Mood in Ultra Marathon Runners
Randomized, prospective, double-blind, placebo-controlled study in ultramarathon runners to evaluate the effects of suplementation with i3.1 probiotic formulation on the relief of common digestive symptoms associated to intense…
- Trial name
- AB-ULTRA (NCT06193096)
- Testing
- Experimental product, Control product
- Where
- Spain
- Volunteers
- 277 people, healthy volunteers welcome
- Sponsor
- AB Biotics, SA
Malignant Tumor of Liver, Randomized Controlled Trial
Application of ICG@HSA Complexes in Fluorescence Image-Guided Laparoscopic Anatomical Liver Resection
This study is a single-center, prospective, randomized controlled trial that aims to compare the efficacy and safety of a new indocyanine green (ICG) administration protocol with the current guideline-recommended protocol for…
- Trial name
- NCT06219096
- Testing
- NIF image-guided laparoscopic anatomical liver resection with the novel ICG@HSA administration, NIF image-guided laparoscopic anatomical liver resection with the guideline-recommended ICG administration
- Where
- China
- Volunteers
- 100 people
- Sponsor
- West China Hospital
Primary Cervical Dystonia
Segmental Muscle Vibration on Pain in Patients With Primary Cervical Dystonia
This pilot study aims to evaluate the effectiveness of Vibration Muscle Stimulation (VMS) in reducing pain and improving quality of life in patients with primary cervical dystonia (CD), a focal dystonia characterized by…
- Trial name
- VIBRA-DYSTONIA (NCT06748846)
- Testing
- Physiotherapy + Occupational therapy + Focal Muscle Vibration
- Where
- Italy
- Volunteers
- 28 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
HR-positive Breast Cancer
Vitamin B12 for Aromatase Inhibitors Associated Musculoskeletal Symptoms in Breast Cancer
Treatment of hormone receptor (HR)-positive breast cancer with Aromatase Inhibitors (AIs) can lead to associated musculoskeletal pain and may cause patients to discontinue important treatment.
- Trial name
- NCT04205786
- Testing
- Vitamin B12, Blood collection, Brief Pain Inventory - Short Form survey
- Where
- United States
- Sponsor
- Case Comprehensive Cancer Center
Stage IV Periodontitis, Orthodontic Tooth Movement
Effect of MOPs During Orthodontic Movement in Periodontitis Patients
Micro-osteoperforations (MOPs) cause cortical bone injuries and consequently increase the expression of inflammatory mediators, allowing for increased bone and periodontal ligament remodeling associated with orthodontic movement.
- Trial name
- MOPorthoperi (NCT06068270)
- Testing
- Micro-ostoperforations (MOPs)
- Where
- Spain
- Volunteers
- 28 people
- Sponsor
- Universidad Complutense de Madrid
Mechanical Neck Pain
Deep Cervical Flexor and Sensorimotor Training for Chronic Neck Pain
This randomized controlled trial aims to investigate the effectiveness of deep cervical flexor muscle training combined with sensorimotor (proprioception) training in patients with chronic mechanical neck pain.
- Trial name
- NCT07040605
- Testing
- Deep cervical flexors muscle training and sensorimotor training, conventional physical therapy exercise
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Al-Neelain University
Student Nursing, Medical-surgical Nursing
The Effect of Video-based Training on the Knowledge Levels of Nursing Students
Although face-to-face education is widely used as a traditional method, emerging computer technology has allowed new training approaches such as video-based training (VBT) platforms to flourish, especially in the last four…
- Conditions
- Student Nursing, Medical-surgical Nursing, Nursing Care, Education
- Trial name
- NCT06371066
- Testing
- experimental group, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 97 people
- Sponsor
- Kırıkkale University
Dry Eye, Dry Eye, Evaporative
Evaluation of Miebo (Perfluorohexyloctane) Eyedrops in Habitual Contact Lens Wearers
Miebo (Perfluorohexyloctane) is a novel, non-aqueous, single entity, preservative free, ophthalmic drop. This drop was recently approved by the Food and Drug Administration (FDA) for the treatment of Meibomian Gland Disease…
- Conditions
- Dry Eye, Dry Eye, Evaporative, Dry Eye Disease, Evaporative Dry Eye
- Trial name
- NCT06176651
- Testing
- Miebo
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Gordon Schanzlin New Vision
Psychotic Disorders, Schizophrenia Spectrum Disorders
Feasibility, Acceptability, and Preliminary Efficacy of Yoga-based Group Intervention for Outpatients With Schizophrenia Spectrum Disorders
A three-arm pilot rater-blinded randomized controlled trial is conducted, comprising Yoga-based Group Intervention (YoGI + TAU) as the experimental condition, a strength and flexibility training (SFT + TAU) group, and treatment…
- Trial name
- YOGIA (NCT07455929)
- Testing
- Yoga-based Group Intervention (YoGI) and treatment as usual (TAU), Strength and Flexibility Training (SFT) and TAU
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Charite University, Berlin, Germany
Schizophrenia, Schizoaffective Disorder
Video as a Tool to Improve Insight in Schizophrenia
The deficit of awareness of pathology (or insight) is a common symptom in patients with schizophrenia and has a negative impact on the prognosis of the disease.
- Trial name
- VideoInsight (NCT02664129)
- Testing
- Video self-observation, Non Self video observation
- Where
- 2 sites in France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Montpellier
Peripheral Arterial Disease, Chronic Limb Ischemia
Improving Radiological Outcomes in Arterial Disease - A Pilot Evaluation of the Pedra Tissue Perfusion Monitoring System
The Pedra Technologies' PedraTM device is a non-invasive, diagnostic device intended to measure foot perfusion by assessing blood flow.
- Trial name
- IROAD (NCT03294902)
- Testing
- Pedra Tissue Perfusion Monitor
- Where
- United Kingdom
- Volunteers
- 68 people
- Sponsor
- Pedra Technology, PTE LTD
Spondylolysis
Effects of Low-intensity Pulsed Ultrasound on Pain and Functional Disability in Patients With Lumbar Spondylolysis
Low-intensity pulsed ultrasound (LIPUS) is effective in accelerating the healing of fractures, reduction in costs to the state, reduction in the numbers of those patients who progress from out-patient care to long term care who…
- Trial name
- NCT04814979
- Testing
- Low-intensity pulsed ultrasound (LIPUS), Routine physical therapy
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- University of Lahore
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