Clinical trials: Experimental Group
HIV, Mental Health
Reducing Stigma and Building Employability Skills for Young People With HIV in Zambia
The goal of this clinical trial is to learn if a program called Kupambana can improve mental health and HIV care outcomes in young people with HIV in Zambia by combining stigma-reduction support with financial and job-skills…
- Conditions
- HIV, Mental Health, Treatment Adherence
- Trial name
- NCT07732660
- Testing
- Stigma Reduction Support Group (SRSG), Financial Literacy, Technical and Vocational Education and Training (TVET)
- Where
- Zambia
- Volunteers
- 100 people
- Sponsor
- University of North Carolina, Chapel Hill
Diabetes Mellitus, Type 2
The Effects of Self-management Education Based on Theory of Planned Behavior on Patients With Type 2 Diabetes
The aims of the study are as follows: To improve self-management intention and behavior of patients with type 2 diabetes (T2 DM).
- Trial name
- NCT02594748
- Testing
- Self-management education, Routine care
- Where
- China
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- University of Turku
Healthy
Cognitive Effects of Life Kinetik-Adapted Physical Activity Cards
The purpose of this study is to investigate the effects of physical activity cards integrated with Life Kinetik exercises on attention, short-term memory, cognitive flexibility, and problem-solving skills in middle school…
- Trial name
- NCT07335848
- Testing
- Life Kinetik Adapted Physical Activity Cards Training, Physical activity cards training
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Enes Sucular
Behavioral Problems, Academic Problems
Effectiveness of School-Based Solution Focused Brief Therapy for Academic and Behavioral Problems in Adolescents
This randomized wait-list controlled trial aims to evaluate the effectiveness of School-Based Solution-Focused Brief Therapy (SFBT) for adolescents experiencing academic and behavioral problems.
- Trial name
- NCT07811648
- Testing
- Solution-Focused Brief Therapy (SFBT)
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- National University of Modern Languages
Pulmonary Disease, Chronic Obstructive
Prevalence of Chronic Airway Obstruction in Subjects With a History of Cigarette Smoking in a Primary Care Setting
This is a cross-sectional study to determine the prevalence of symptomatic airway obstruction using the LFQ as a screening tool in primary care patients with a history of cigarette smoking and to provide descriptive data of this…
- Trial name
- NCT01013948
- Testing
- Non-Interventional
- Where
- 40 sites in United States
- Volunteers
- 1,574 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Takayasu's Arteritis
Clinical Study of Anti-tumor Necrosis Factor Therapy in Patients With Takayasu Arteritis
Clinical study of anti-tumor necrosis factor therapy in patients with Takayasu arteritis. This study is single arm (anti Tumor necrosis factor therapy only) clinical trial. Enrolled patients will be 11
- Trial name
- NCT02457585
- Testing
- remicade (anti tumor necrosis factor inhibitor)
- Where
- South Korea
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Guilt, Depressive Symptoms
Guilt Focused Psychological Intervention
Participants in the intervention study will be 120 caregivers with guilt feelings linked with care and high levels of emotional distress (anxiety and/or depression), randomly allocated to the intervention conditions: intervention…
- Conditions
- Guilt, Depressive Symptoms, Anxious Symptoms, Stress, Physiological
- Trial name
- LONG-CARE (NCT04656808)
- Testing
- Guilt Focused Intervention, Cognitive behavioral therapy
- Where
- Spain
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Universidad Rey Juan Carlos
Body Weight Changes
Pre Competition Weight Loss of Athletes
The objective of this observational study is to assess the long-term impact of a combined slow and rapid weight reduction strategy on the physiological performance, mental state, and sleep quality of male freestyle wrestlers.
- Trial name
- NCT06543017
- Testing
- Experimental group
- Where
- China
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Chengdu Sport University
Cholecystitis
Prophylactic TAP Block in Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy is the gold standard for cholelithiasis, yet postoperative pain remains a clinical challenge. Ultrasound-guided transversus abdominis plane (TAP) block has been proposed as an effective analgesic…
- Trial name
- NCT07871617
- Testing
- Analgesic, Analgesic transversus abdominal plane blockade (Bupivacaine)
- Where
- Mexico
- Volunteers
- 60 people
- Sponsor
- Hospital General de Chihuahua - Dr. Salvador Zubirán Anchondo
Pancreatic Adenocarcinoma Resectable
Adjuvant Pancreatic Therapy Guided by MRD
Pancreatic adenocarcinoma (PAAD) is a leading cause of cancer-related deaths worldwide. Although surgical resection can be curative, the 5-year overall survival (OS) rate after resection alone is approximately 20%.
- Trial name
- ADAPT-MRD (NCT06966440)
- Testing
- circulating tumor DNA (ctDNA)-based MRD, adjuvant chemotherapy regimens
- Where
- China
- Volunteers
- 856 people
- Sponsor
- Ruijin Hospital
Nasopharyngeal Carcinoma, Nutritional Support
Effect of Oral Nutritional Supplements on Body Weight Loss of Patients With Nasopharyngeal Carcinoma
Concurrent chemoradiotherapy(CCRT) is the principal treatment for nasopharyngeal carcinoma(NPC). Studies have shown that malnutrition is very common in patients with NPC after chemoradiotherapy.
- Trial name
- NCT04823468
- Testing
- Abbott®Ensure, Intensity Modulated Radiation Therapy, cisplatin
- Where
- 13 sites in China
- Volunteers
- 236 people
- Sponsor
- Jinsheng Hong
Type 2 Diabetes
Clinical Trial to Assess the Efficacy and Safety of YYC405 in Type 2 Diabetes Patients
Phase 3 study to assess the Efficacy and Safety of YYC405 in Type 2 Diabetes Patients
- Trial name
- NCT05226897
- Testing
- YYC405-T, Metformin≥1000mg, Dapagliflozin 10mg
- Where
- South Korea
- Volunteers
- 256 people
- Sponsor
- Yooyoung Pharmaceutical Co., Ltd.
Postoperative Nausea and Vomiting, Breast Cancer Female
Ramosetron on Late PONV (Postoperative Nausea and Vomiting)
The purpose of this study was to evaluate the effectiveness of additional ramosetron injection for controlling late postoperative nausea and vomiting (PONV) after breast surgery in high risk PONV patients.
- Trial name
- NCT05326360
- Testing
- Ramosetron Hydrochloride
- Where
- South Korea
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Pusan National University Hospital
Polycythemia Vera, Essential Thrombocythemia
AVAJAK: Apixaban/Rivaroxaban Versus Aspirin for Primary Prevention of Thrombo-embolic Complications in JAK2V617F-positive Myeloproliferative Neoplasms
Philadelphia-negative myeloproliferative neoplasms (MPN) are frequent and chronic myeloid malignancies including Polycythemia Vera (PV), essential thrombocythemia (ET), Primary Myelofibrosis (PMF) and Prefibrotic myelofibrosis…
- Conditions
- Polycythemia Vera, Essential Thrombocythemia, Prefibrotic/Early Primary Myelofibrosis, JAK2 V617F
- Trial name
- AVAJAK (NCT05198960)
- Testing
- Direct Oral Anticoagulants, Low-dose aspirin
- Where
- 42 sites in France
- Volunteers
- 1,308 people
- Sponsor
- University Hospital, Brest
Breast Cancer
Evaluating the Impact of Evidence-based Information About Mammography on Breast Cancer Screening Decisions
Patient decision aids are tools that help guide individuals through a healthcare-related decision making process. They help users combine evidence-based information and recommendations by a health care provider with their…
- Trial name
- NCT03631758
- Testing
- Evidence-based information, Patient Decision Aid
- Where
- Canada
- Volunteers
- 209 people, healthy volunteers welcome
- Sponsor
- McMaster University
Varicella
Protective Effect, Safety and Immunogenicity of Live Attenuated Varicella Vaccine in Anhui Province
This is Phase 4 clinical trial of live attenuated varicella vaccines manufactured by Sinovac (Dalian) Vaccine Technology Co., Ltd .The purpose of this study is to evaluate the protective effect of varicella vaccine in children…
- Trial name
- NCT05470855
- Testing
- Live attenuated varicella vaccine
- Where
- 5 sites in China
- Volunteers
- 45,400 people
- Sponsor
- Sinovac (Dalian) Vaccine Technology Co., Ltd.
Influenza
Lingdancao Granules in the Treatment of Seasonal Influenza
Name of study: Randomized, Double-Blinded, Oseltamivir-and-Placebo-Controlled Clinical Study about Lingdancao Granules in the Treatment of Seasonal Influenza Objective: Preliminary evaluation on the efficacy and safety of…
- Trial name
- NCT02662426
- Testing
- Lingdancao granules, analogous oseltamivir phosphate capsule, Oseltamivir phosphate capsule
- Volunteers
- 318 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
End Stage Kidney Disease (ESRD)
Effect of the Amplifi™ Vein Dilation System on Outflow Vein Dilation and AV Fistula Maturation (AMPLIFI-1)
The AMPLIFI-1 Study is a prospective, multicenter pivotal clinical trial designed to evaluate the safety and effectiveness of the Amplifi™ Vein Dilation System in patients requiring distal arteriovenous fistula (AVF) creation for…
- Trial name
- AMPLIFI-1 (NCT07211035)
- Testing
- The Amplifi System is a temporary extracorporeal blood pump designed to deliver controlled flow through a peripheral vein for 24-72 hours prior to AVF creation., Standard of Care (AVF creation)
- Where
- 2 sites in United States
- Volunteers
- 160 people
- Sponsor
- Amplifi Vascular, Inc.
Severe Mental Illness
The Effects of Oxytocin Administration to Patients and Therapists on Physiological Synchronization
Introduction: Oxytocin (OT) is a nine-amino acid neuropeptide, known to have a fundamental role in social communication. In a recent randomized, double-blind, placebo-controlled study carried out in Shalvata Mental Health Center…
- Trial name
- NCT05432089
- Testing
- Intranasal Oxytocin
- Where
- Israel
- Volunteers
- 120 people
- Sponsor
- Shalvata Mental Health Center
Fatigue, Sleep Disturbance
Comparing Effect of Intradialytic Aerobic Exercise Versus Incentive Spirometer on Fatigue and Sleep Quality Among Hemodialysis Patients.
In order to accomplish the objectives of this investigation, a single-blind experimental comparative design was implemented to evaluate the impact of intradialytic aerobic exercise and Incentive Spirometer on sleep quality and…
- Conditions
- Fatigue, Sleep Disturbance, Hemodialysis Complication
- Trial name
- NCT07386691
- Testing
- intradialytic aerobic exercise versus incentive spirometer
- Where
- Iraq
- Volunteers
- 169 people
- Sponsor
- University of Baghdad
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