Clinical trials: Ketorolac
Sore Throat
S.L. Spray Solution® and Difflam® and Acular®Spray for the Prevention of Postoperative Sore Throat
The purpose of intubation for patients under general anesthesia is to maintain their respiratory function. However, this procedure does cause a postoperative sore throat.
- Trial name
- NCT02608788
- Testing
- S.L.®, Difflam Forte ®, Acular®
- Volunteers
- 380 people
- Sponsor
- Chang Gung Memorial Hospital
Bowel Obstruction
A Health Economic Trial in Adult Patients Undergoing Open Colectomy MA402S23B301
This study is designed to compare the standard of care against EXPAREL (bupivacaine liposome extended-release injectable suspension) to determine if total opioid consumption is reduced when using EXPAREL therefore possibly…
- Trial name
- IMPROVE-Open (NCT01507220)
- Testing
- morphine sulfate, bupivacaine liposome extended-release injectable suspension
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Pacira Pharmaceuticals, Inc
Pain, Postoperative, Osteoarthritis, Knee
Comparing Local Anesthetic Injections to Nerve Blocks for Pain Control After Total Knee Replacement
Why are we doing this study? People who have knee replacement surgery often feel pain afterward. Doctors use different methods to control this pain.
- Conditions
- Pain, Postoperative, Osteoarthritis, Knee, Arthroplasty, Replacement, Knee
- Trial name
- LIA-PNB-TKA (NCT07744503)
- Testing
- Continuous Femoral and Sciatic Nerve Block (Ropivacaine), Local Infiltration Analgesia (Ropivacaine, Ketorolac, Epinephrine)
- Where
- Austria
- Volunteers
- 78 people
- Sponsor
- Christopher Male
Laparoscopic Cholecystectomy
Quadratus Lumborum Block vs Transversus Abdominis Plane Block for Post-cholecystectomy Analgesia
In laparoscopic cholecystectomy, overall pain is a conglomerate of three different and clinically separate components: incisional pain (somatic pain) due to trocar insertion sites, visceral pain (deep intra abdominal pain), and…
- Trial name
- NCT03323684
- Testing
- Quadratus lumborum block Group (QL), Transversus abdominis plane Group (TAP), Control group (C)
- Where
- 2 sites in Egypt
- Volunteers
- 159 people
- Sponsor
- Mansoura University
Post-operative Pain, Post-partum Pain
Increased Ketorolac Administration After Cesarean Section and Its Effect on Opioid Use: a Randomized Control Trial
To evaluate the efficacy of increased ketorolac in reducing opioid use after cesarean section.
- Conditions
- Post-operative Pain, Post-partum Pain, Cesarean Section Complications
- Trial name
- NCT03678675
- Testing
- Ketorolac
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Tufts Medical Center
Pain, Postoperative, Pain
Use of Local Infiltration Analgesia Following Total Hip Arthroplasty
The primary aim of this study is to evaluate if multiple postoperative administrations with a solution of ropivacaine, ketorolac and epinephrine into the operating field through a catheter would affect morphine consumption.
- Trial name
- NCT01344395
- Testing
- ropivacaine and ketorolac, Ketorolac
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- University of Aarhus
Total Laparoscopic Hysterectomy, Patient-controlled Analgesia
Two-channel Intravenous Patient-controlled Analgesia (IV-PCA) After Total Laparoscopic Hysterectomy (TLH)
The purpose of this study is to compare the dual channel intravenous patient-controlled analgesia (IV-PCA) with single channel elastomeric pump (only one channel of dual channel pump is used for blinding and the other channel is…
- Trial name
- NCT04082039
- Testing
- convetional PCA method unsing only 1-channel, utilizing 2-channel
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Korea University Guro Hospital
Pain, Postoperative
Ketolorac Versus Saline at Laparoscopic Incision Sites
Pain control following surgery is a critical aspect of patient care. Pain at incision sites in laparoscopic surgery contributes to overall pain felt by a patient.
- Trial name
- NCT01374828
- Testing
- Ketolorac
- Where
- United States
- Sponsor
- The Cleveland Clinic
Arthritis Knee, Arthritis of Hip
Intraarticular Injections of the Hip and Knee With Triamcinolone Versus Ketorolac: A Randomized Controlled Trial
Clinicians commonly utilize intraarticular injections to treat symptomatic primary arthritis. Steroid injections are common yet have immune-modulating effects and can alter gene expression which may delay definitive arthroplasty…
- Trial name
- NCT04441112
- Testing
- Ketorolac Intraarticular Injection, Triamcinolone Intraarticular Injection
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Saint Alphonsus Regional Medical Center
Pain, Postoperative, Anesthesia Complication
Laparoscopic Cholecystectomy: General Anesthesia With Opioid Versus General Opioid Free Anesthesia
The use of opioid during surgery can cause side effects and may delay hospital discharge. Some studies have shown balanced sparing opioid anesthesia can optimize the side effects and and the time of discharge.
- Conditions
- Pain, Postoperative, Anesthesia Complication, Nausea, Vomiting
- Trial name
- GALOFF (NCT02953210)
- Testing
- dexter ketamine, Lidocaine Hydrochloride, Fentanyl Hydrochloride
- Where
- 2 sites in Brazil
- Volunteers
- 40 people
- Sponsor
- Federal University of São Paulo
End Stage Liver Disease, Lung Cancer
Antinociceptive Modalities on Ischemia Reperfusion Injury
Postoperative pain caused by surgery-associated tissue injury is a major concern for all the clinical practitioners. Because it affects multiple systems and induces physiological, immunological and psychological changes.
- Trial name
- NCT01932918
- Testing
- Patient controlled analgesia
- Where
- Taiwan
- Volunteers
- 142 people
- Sponsor
- National Taiwan University Hospital
Pelvic Organ Prolapse
Factors Affecting Perioperative Outcomes
The specific aim of this study is to determine if pre-existing depression and anxiety affect perioperative outcomes measures patients undergoing surgery for pelvic organ prolapse.
- Trial name
- NCT01530191
- Where
- United States
- Sponsor
- University of Oklahoma
Migraines
Comparison of Ketorolac Nasal Spray to Sumatriptan Nasal Spray and Placebo for Acute Treatment of Migraine
The investigators propose to test the efficacy of ketorolac nasal spray versus sumatriptan nasal spray versus placebo for acute abortive therapy of migraine head pain as well as for migraine associated symptoms including nausea…
- Trial name
- KSPN (NCT01807234)
- Testing
- Ketorolac, Sumatriptan
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Johns Hopkins University
Orthopaedic Fractures
Improving Pain Management and Long Term Outcomes Following High Energy Orthopedic Trauma (Pain Study)
The purpose of this study is to definitively resolve questions regarding the use of multimodal pharmacologic pain management for orthopedic trauma patients in the context of a multicenter, randomized clinical trial.
- Trial name
- PAIN (NCT01789216)
- Testing
- NSAID, Gabapentinoids
- Where
- 17 sites in United States
- Volunteers
- 450 people
- Sponsor
- Major Extremity Trauma Research Consortium
Nephrectomy, Laparoscopic Donor Nephrectomy
Intravenous Ketorolac for Postoperative Pain in Laparoscopic Donor Nephrectomy
The purpose of this study is to determine whether continuous intravenous ketorolac infusion reduces pain in patients who are having laparoscopic surgery to donate a kidney.
- Trial name
- NCT00765232
- Testing
- Ketorolac
- Where
- United States
- Volunteers
- 111 people
- Sponsor
- Mayo Clinic
Cesarean Section
Enhanced Recovery at Cesarean Birth to Improve Postoperative Outcomes and Reduce Postoperative Length of Stay
To determine whether women randomized to an enhanced recovery program will have improved postoperative outcomes including improved breastfeeding initiation and continuation, reduction in hospital length of stay without…
- Trial name
- ERAC (NCT02956616)
- Testing
- ketorolac, Chewing Gum, Enhanced Recovery Protocol
- Where
- United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Hysterectomy, Tubal Excision
Etoricoxib for Routine Post-operative Pain Prophylaxis in Laparoscopic Surgery
The aim of this trial is to compare if a single dose of oral etoricoxib 120 mg will have equal post-operative analgesic efficacy as an optimal regiment of intravenous ketorolac 30 mg + 30 mg during the first 18 hours (+/- 1 hour)…
- Conditions
- Hysterectomy, Tubal Excision, Ovariectomy, Postoperative Pain
- Trial name
- NCT00373464
- Testing
- etoricoxib
- Where
- Norway
- Volunteers
- 126 people
- Sponsor
- Ullevaal University Hospital
Wide Excision, Postoperative Pain
Local Anesthetic Infiltration for Pain Control After Orthopedic Wide Excision
This study evaluates whether injecting a local anesthetic mixture (ropivacaine, morphine, ketorolac, and epinephrine) under the skin at the incision site before wound closure reduces pain after orthopedic wide excision surgery…
- Trial name
- NCT07753629
- Testing
- Ropivacaine-Morphine-Ketorolac-Epinephrine-Cefuroxime Mixture, Cefuroxime-Saline Mixture
- Volunteers
- 58 people
- Sponsor
- Seoul National University Hospital
Breast Neoplasms
Perioperative Inflammation and Breast Cancer Outcome
It is increasingly recognized the NSAIDS (nonsteroidal antiinflammatory drug) might prevent the several cancers. In breast cancer, the role of NSAIDS (nonsteroidal antiinflammatory drug) has been suggested.However, there was no…
- Trial name
- NCT02141139
- Testing
- NSAIDS (ketorolac and ibuprofen)
- Where
- South Korea
- Volunteers
- 1,568 people
- Sponsor
- Samsung Medical Center
Back Pain, Chronic Pain
Haloperidol for Pain Control in Patients With Acute Musculoskeletal Back Pain in the Emergency Department
Single center, double-blind, randomized, controlled trial in patients who present to the emergency department (ED) with a chief complaint of back pain.
- Trial name
- NCT06395428
- Testing
- Haloperidol, Ketorolac Tromethamine
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Western Michigan University School of Medicine