Clinical trials: Misoprostol
Blood Loss, Surgical, Second Trimester Abortion
MisOpRostol Effect on Second Trimester Abortion Blood Loss
Although serious complications from second trimester abortion are rare hemorrhage is the most common cause of procedural abortion related morbidity and mortality.
- Trial name
- MORESTABL (NCT06078501)
- Testing
- Misoprostol 400mcg buccal
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Stanford University
Cervical Ripening
Cervical Ripening With Misoprostol vs Isosorbide Mononitrate ; A Parallel -Arm Randomized Controlled Trial
This randomized controlled trial compared misoprostol and isosorbide mononitrate (IMN) for cervical ripening in prolonged pregnancies.
- Trial name
- NCT07121634
- Testing
- Misoprostol 25 µg Vaginal, Isosorbide Mononitrate
- Where
- Iraq
- Volunteers
- 80 people
- Sponsor
- Raid M. Al-Ani
Labor Induction
Effect of Dexamethasone on Labour Induction in Term Pregnancies
The aim of the study is to assess the effect of dexamethasone on labour induction in term pregnancies. Primary outcome: The interval between initiation of induction and beginning of the active phase of labour.
- Trial name
- NCT07109258
- Testing
- Dexamethasone (Decadron) 8mg IM injection, Misoprostol 25 mcg, Both Misoprostol 25 mcg & Dexamethasone 8mg IM injection
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Cairo University
Myomectomy; Surgical Blood Loss
Rectal Misoprostol as a Hemostatic Agent During Abdominal Myomectomy
Purpose is to identify if misoprostol in addition to local vasopressin decreases blood loss when compared to vasopressin alone, which is our current practice at this time.
- Trial name
- NCT03064568
- Testing
- Misoprostol 200Mcg Tab
- Where
- 3 sites in United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Post Partum Hemorrhage
Tranexamic Acid Versus Sublingual Misoprostol in Reducing Blood Loss During Elective CS in High Risk Cases
The Efficacy and safety of Preoperative Intravenous Tranexamic acid versus Sublingual misoprostol in reducing blood loss during and after Elective Cesarean section among high risk pregnant cases.
- Trial name
- NCT04117243
- Testing
- Misoprostol, Tranexamic acid, Oxytocin
- Where
- Egypt
- Volunteers
- 345 people
- Sponsor
- Cairo University
Misoprostol, Respiratory Distress Syndrome (RDS) of Neonate
Misoprostol Before Caesarean Section
The aim of our study is to evaluate the efficacy of Misoprostol before elective cesarean section in pregnant women with gestational age less than 38 weeks for preventing the occurrence of neonatal respiratory morbidity.
- Conditions
- Misoprostol, Respiratory Distress Syndrome (RDS) of Neonate, Caesarean Section
- Trial name
- Miso/CS (NCT06946914)
- Testing
- Misoprostol
- Where
- Egypt
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Postpartum Hemorrhage
Double Simultaneous Uterotonic Agents Versus Single Agent Regimen to Prevent Early Postpartum Hemorrhage
To determine the effectiveness of using two medications simultaneously versus one medication, as is standard of care, in preventing early postpartum hemorrhage.
- Trial name
- NCT05245227
- Testing
- Sublingual Misoprostol, IV Oxytocin
- Where
- United States
- Volunteers
- 1,358 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
Induction of Labor
Misoprostol Versus Dinoprostone in Induction of Labor
Endogenous prostaglandins, derived from the uterus, cervix, placenta, and membranes of fetus, are essential for cervical ripening ,the investigators aimed to compare Misoprostol and Dinoprostone as regarding to cost-effectiveness…
- Trial name
- NCT06909721
- Testing
- Misoprostol
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Al-Azhar University
Fetal Growth Restriction
Prostaglandins Versus Trans-cervical Balloon for Induction of Labor in Fetal Growth Restriction (PROBIN)
The goal of this randomized trial is to compare two methods of induction in a fetal growth restriction population. The main question it aims to answer is: Is trans-cervical balloon superior to prostaglandins in reducing the…
- Trial name
- PROBIN (NCT05674487)
- Testing
- Trans-cervical balloon, Misoprostol
- Where
- France
- Volunteers
- 774 people
- Sponsor
- University Hospital, Bordeaux
Cervical Ripening and Induction of Labor
Comparison Between Vaginal Misoprostol Gel and Oral Misoprostol Solution in Induction of Labor
The goal of this clinical trial is to study the efficacy of vaginal versus oral misoprostol solution in cervical ripening for induction of labor.
- Trial name
- NCT06874049
- Testing
- Vaginal misoprostol, Oral misoprostol solution (OMS)
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hagar Muhammad Abdulfattah Muhammad
Induction of Labor
Induction of Labour at Term With Low Dose Oral Misoprostol Versus a Foley Catheter
Comparison of efficacy and safety of low-dose oral Misoprostol versus folley catheter for preinduction in women with an immature cervix at term.
- Trial name
- NCT06056141
- Testing
- Misoprostol 200mcg Tab, Foley Catheter
- Where
- 2 sites in Kazakhstan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Kazakhstan's Medical University "KSPH"
Induction of Labor
Sequential Use of Foley's Catheter and Misoprostol Versus Misoprostol Alone for Induction of Labour: a Multicentre Randomised Controlled Trial
Evaluation of efficacy of inducing labour using a Foley's catheter and low dose oral misoprostol sequentially, in comparison with low dose oral misoprostol alone.
- Trial name
- NCT06249815
- Testing
- Misoprostol 200mcg Tab
- Where
- 2 sites in Kazakhstan
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Kazakhstan's Medical University "KSPH"
Pregnancy
Elective Induction of Nulliparous Labor
Primary outcome: to evaluate the effect of elective induction of labor (IOL), at 39 weeks gestation, on cesarean delivery rates in nulliparous women compared to expectant management (EM).
- Trial name
- NCT01076062
- Testing
- Induction of Labor
- Where
- United States
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Madigan Army Medical Center
Medical Abortion
Effectiveness and Safety of Combination Mifepristone/Misoprostol for Medical Abortion
National multi-center non interventional study aiming at investigating the effectiveness and safety of the combination mifepristone-misoprostol prescribed in Canada to women for medical termination of pregnancy at or before 63…
- Trial name
- MiMAC (NCT04905251)
- Testing
- Mifepristone-Misoprostol
- Where
- 6 sites in Canada
- Volunteers
- 129 people
- Sponsor
- Linepharma International LTD
Induction of Labour
Comparison of the Effectiveness, Safety, and Satisfaction of Different Methods for Labor Induction
The objective of this interventional study is to compare the effectiveness, safety, and patient satisfaction associated with two commonly used methods of labor induction: low-dose oral misoprostol and the vaginal delivery system…
- Trial name
- NCT06794385
- Testing
- dinoprostone vaginal delivery system, low dose peroral misoprostol
- Where
- Slovenia
- Volunteers
- 200 people
- Sponsor
- University Medical Centre Ljubljana
Postpartum Hemorrhage
Comparison Between Preoperative Vaginal and Postoperative Sublingual Misoprostol for Prevention of Postpartum Hemorrhage During Cesarean Section
Cesarean section (CS) is one of the most frequently performed operative interventions worldwide [1]. Cesarean section rates increase each year throughout the world.
- Trial name
- NCT06765473
- Testing
- Misoprostol
- Volunteers
- 400 people
- Sponsor
- Assiut University
Induction of Labor
A Randomized Trial of Oral Misoprostol Alone Versus Oral Misoprostol Followed by Oxytocin for Labour Induction
The primary objective of the trial is to assess the following: In women who have undergone cervical preparation with oral misoprostol as part of labour induction for hypertensive disease in India, is augmentation using oral…
- Trial name
- MOLI (NCT03749902)
- Testing
- Oral misoprostol, Oxytocin
- Where
- 3 sites in India
- Volunteers
- 520 people
- Sponsor
- University of Liverpool
Hysteroscopy, Cervical Ripening
Significance of Misoprostol-induced Cervical Ripening Prior to Hysteroscopy
The goal of this prospective study is to evaluate the efficacy and safety of misoprostol for cervical ripening prior to hysteroscopy
- Trial name
- NCT06726278
- Testing
- Misoprostol 400mcg Tab
- Where
- Pakistan
- Volunteers
- 539 people
- Sponsor
- Hayat Abad Medical Complex, Peshawar
Pregnancy
Evaluation of Telemedicine Medical Abortion Service in Ecuador
This research seeks to demonstrate that a telemedicine model for the provision of legal abortion services in Ecuador is safe, feasible and acceptable to users requesting a medication abortion and who are less than 12 weeks…
- Trial name
- NCT06270056
- Testing
- Misoprostol
- Where
- 3 sites in Ecuador
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Blood Loss, Surgical, Blood Loss, Postoperative
Comparative Study Between Preoperative and Postoperative Rectal Misoprostol
Cesarean delivery (CD) is the most common major surgical procedure undergone by women around the world. Over the past two decades, there has been a witnessed increase in rates of caesarean deliveries, which continues to rise…
- Trial name
- NCT06049160
- Testing
- Misoprostol
- Where
- Egypt
- Volunteers
- 128 people
- Sponsor
- Egymedicalpedia