Clinical trials: Propranolol, completed
Brain Injuries, Craniocerebral Trauma
DASH After TBI Study: Decreasing Adrenergic or Sympathetic Hyperactivity After Traumatic Brain Injury
The investigators intend to determine the effect of adrenergic blockade on 1) short-term physiology, behavior, and cognition and 2) long-term neuropsychological outcomes after severe Traumatic Brain Injury (TBI).
- Conditions
- Brain Injuries, Craniocerebral Trauma, Trauma, Nervous System, Traumatic Brain Injury
- Trial name
- NCT01322048
- Testing
- IV Propranolol and Per Tube Clonidine
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Vanderbilt University
Healthy
Food Study of Propranolol Hydrochloride Extended-Release Capsules 160 mg and Inderal® LA Capsules 160 mg
The objective of this study was to investigate the bioequivalence of Mylan's propranolol hydrochloride extended-release 160 mg capsules to Wyeth's Inderal® LA 160 mg capsules following a single, oral 160 mg (1 x 160 mg) dose…
- Trial name
- NCT00647608
- Testing
- Propranolol Hydrochloride Extended-Release Capsules 160 mg, Inderal® LA Capsules 160 mg
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Mylan Pharmaceuticals Inc
Infantile Hemangioma
Nadolol for Proliferating Infantile Hemangiomas
The purpose of this study is to explore the efficacy and safety of Nadolol in hemangiomas of infancy. The secondary objective is to assess the feasibility of conducting a randomized controlled trial comparing nadolol with…
- Trial name
- NCT01010308
- Testing
- Nadolol
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- The Hospital for Sick Children
Neurocardiogenic Syncope
Propranolol to Treat Fainting Due to Sympathoadrenal Imbalance
This study will examine the effectiveness of the drug propranolol in preventing fainting in patients with sympathoadrenal imbalance (SAI).
- Trial name
- NCT00060866
- Testing
- Propranolol
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Liver Cirrhosis, Portal Hypertension
HVPG for Rebleeding Risk Stratification
Background: In patients with cirrhosis on secondary prevention of variceal rebleeding with non-selective beta-blockers (NSBBs), the risk of rebleeding and death is markedly higher in those failing to achieve a good hemodynamic…
- Trial name
- NCT01751191
- Where
- 2 sites in Spain
- Volunteers
- 338 people
- Sponsor
- Hospital Clinic of Barcelona
Proliferative Diabetic Retinopathy
Propranolol for Diabetic Retinopathy
This study is investigating if the oral beta antagonist propranolol can induce regression of retinal neovascularization associated with proliferative diabetic retinopathy.
- Trial name
- NCT01535495
- Testing
- Propranolol
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Wisconsin, Madison
Hemangioma
Efficacy and Safety of Propranolol Versus Atenolol on the Proliferative Phase of Infantile Hemangioma
The purpose of this study is to compare the efficacy of orally administered propranolol versus atenolol in the treatment of potentially disfiguring or functionally threatening IHs.
- Trial name
- NCT02342275
- Testing
- Propranolol, Atenolol
- Where
- China
- Volunteers
- 377 people, healthy volunteers welcome
- Sponsor
- West China Hospital
Hemangioma
The Safety and Efficiency of Propranolol as an Initial Treatment for Pediatric Hemangioma
The purpose of this study is to determine the safety and efficiency of Propranolol as an initial treatment for pediatric hemangioma.
- Trial name
- NCT01908972
- Testing
- Prednisolone, Propranolol
- Where
- South Korea
- Volunteers
- 34 people
- Sponsor
- Seoul National University Hospital
Cardiovascular Diseases, Coronary Disease
Multicenter Investigation of Limitation of Infarct Size (MILIS)
To assess the ability of two separate therapeutic interventions, propranolol and hyaluronidase, to limit the ultimate size of an acute myocardial infarction.
- Conditions
- Cardiovascular Diseases, Coronary Disease, Heart Diseases, Myocardial Infarction
- Trial name
- NCT00000493
- Testing
- propranolol, hyaluronidase
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Asthma
Beta Blockers for the Treatment of Asthma
Current asthma medicines include inhalers. A common inhaler used in asthma is called a beta-agonist (for example salbutamol). They improve asthma symptoms by stimulating areas in the human airway resulting in widening of the…
- Trial name
- NCT01074853
- Testing
- propranolol
- Where
- United Kingdom
- Volunteers
- 18 people
- Sponsor
- University of Dundee
Kidney Disease
Pharmacokinetic Study in Patients With Chronic Kidney Disease and Healthy Volunteers
The purpose of this study is to find out how chemicals in the blood of patients with chronic kidney disease affect how medications are removed from the body.
- Trial name
- CKD (NCT01087749)
- Testing
- Propranolol, Losartan, Eprosartan
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Atrial Fibrillation
Effect of Prophylaxy of Amiodarone and Propranolol and Amiodarone With Propranolol in Prevention of Atrial Fibrillation Post Coronary Artery Bypass Graft
Atrial fibrillation is the most common arrhythmia post coronary bypass surgery, currently B-blockers are the class I indication to prevent AF post CABG.
- Trial name
- NCT00654290
- Testing
- Amiodarone + Propranolol, Amiodarone, Propranolol
- Where
- Iran
- Volunteers
- 240 people
- Sponsor
- Shiraz University of Medical Sciences
Skin Diseases, Surgical Site Infection
Surgical Hand Antisepsis With Propan-ol-1 60% Per Rubbing and Scrubbing
The present study evaluates the effects of to compare bactericidal efficacy using the reference antiseptic product propan-ol-1 60% using the hand rub method versus hand scrub method in order to test if pass the standard european…
- Trial name
- NCT04446923
- Testing
- Hand antisepsis by scrub
- Where
- Spain
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Ascites
To Study the Effect of Nonselective Beta Blockers in Advanced Stage Liver Disease With Ascites
Cirrhosis is the leading cause of death in India and worldwide and leading causes in developed world include alcoholic liver disease, hepatitis C, and more recently, non-alcoholic fatty liver disease (NAFLD), non-alcoholic…
- Trial name
- NSBB (NCT02649335)
- Testing
- Propranolol, Endoscopic variceal ligation (EVL)
- Where
- India
- Volunteers
- 190 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Chronic Obstructive Pulmonary Disease
Beta-Blocker in Chronic Obstructive Pulmonary Disease (COPD) Study
Smoking causes both smoking related lung disease (COPD) and ischaemic heart disease. These are very common conditions and many patients have both diseases.
- Trial name
- BOLD (NCT00745043)
- Testing
- bronchodilator response
- Where
- New Zealand
- Volunteers
- 11 people
- Sponsor
- Waikato Hospital
Postural Orthostatic Tachycardia Syndrome
Effect of Medical Treatment and Prognosis of Postural Orthostatic Tachycardia Syndrome (POTS)
The purpose of the study is to investigate effect of medical treatment and prognosis of Postural Orthostatic Tachycardia Syndrome (POTS)
- Trial name
- POTS (NCT02171988)
- Testing
- Propranolol, Bisoprolol, Propranolol+pyridostigmine
- Where
- South Korea
- Volunteers
- 150 people
- Sponsor
- Seoul National University Hospital
Sickle Cell Disease
Study of Propranolol as Anti-Adhesive Therapy in Sickle Cell Disease (SCD)
An open label, prospective, randomized cross-over phase II study in up to 60 sickle cell patients who are either homozygous for Hb S or have HbSB0 thalassemia.
- Trial name
- NCT01077921
- Testing
- Propranolol
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Laura M. De Castro, MD
Obstructive Sleep Apnea
Propranolol for Sleep Apnea Therapy
The primary objective of this study is to test whether a beta blocker, propranolol, lowers the overnight heart rate sleep in obstructive sleep apnea (OSA) during CPAP withdrawal.
- Trial name
- ProSAT (NCT03049306)
- Testing
- Propranolol Oral Tablet
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Johns Hopkins University
Hypertension Secondary to Kidney Transplant
Reduction of Night-time Blood Pressure in Pediatric Renal Transplant Recipients
The proposed study investigated the effect of chronotherapeutic alteration of anti-hypertensive medication on nocturnal hypertension and end-organ injury in pediatric renal transplant recipients who are non-dippers.
- Trial name
- NCT01007994
- Testing
- New Medication: Enalapril, Isradipine, Propranolol
- Where
- 2 sites in United States
- Volunteers
- 33 people
- Sponsor
- Northwell Health
Duration of Labor
Does Oral Propranolol Accelerate Labor Induction/Augmentation With Oxytocin in Nulliparous Women in Abakaliki?
Labour is usually physiologic, spontaneous and progressive, but occasionally, there may be the need for induction or augmentation of labour especially in nulliparous women, who are at increased risk of dysfunctional labour.
- Trial name
- NCT05251610
- Testing
- 20mg oral propranolol and oxytocin, Oxytocin only
- Where
- Nigeria
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Darlington-Peter Chibuzor Ugoji