Clinical trials: Vitamin C
Cardio-pulmonary Bypass, Cardiovascular Diseases
Dietary Supplements in Patients With Coronary Artery Bypass Grafting for Improving the Quality of Healthcare Delivery.
Cardiovascular disease (CVD) remains the leading cause of death worldwide. Prevention of CAD by targeting modifiable factors remains a key public health priority. L-Ascorbic Acid (Vitamin C - Vit.
- Conditions
- Cardio-pulmonary Bypass, Cardiovascular Diseases, Omega-3 Polyunsaturated Fatty Acids, Omega-3 Supplementation
- Trial name
- NCT06995586
- Testing
- Vitamin C, Omega 3 PUFA (EPO/DHA), Lignin, Lactulose
- Where
- Cyprus
- Volunteers
- 108 people
- Sponsor
- Nicosia General Hospital
ARDS
Vitamin C Versus Nitric Oxide in Prolonged Ventilation
This a prospective double-blind study done in King Abdul-Aziz specialist hospital between January 2019 and April 2020 in the intensive care unit on 60 patients with difficult weaning and ventilated for 10 days.
- Trial name
- NCT04411160
- Testing
- Vitamin C, Nitric Oxide, ventilators
- Where
- Saudi Arabia
- Volunteers
- 60 people
- Sponsor
- King Abdul Aziz Specialist Hospital
Nonmelanoma Skin Cancer, Basal Cell Carcinoma
Vitamin D Effects on Immune Microenvironment of Nonmelanoma Skin Cancer After Photodynamic Therapy (PDT)
This research study is for people who have been diagnosed with a nonmelanoma skin cancer (either basal cell carcinoma or squamous cell carcinoma) and are planning to receive either Mohs surgery or ED\&C (electrodessication \&…
- Conditions
- Nonmelanoma Skin Cancer, Basal Cell Carcinoma, Squamous Cell Carcinoma
- Trial name
- NCT07241585
- Testing
- Vitamin D (VitD), Photodynamic therapy (PDT), Mohs surgery or electrodessication & curettage (ED&C) (standard of care)
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Case Comprehensive Cancer Center
Consumer Behavior, Consumer Preference
Front-of-package Marketing on Fruit Drinks: Online RCT
This study will test the independent and combined effects of front-of-package claims, imagery, nutrition disclosures, and added sugar warning labels on parents' purchases and perceptions of beverages for their children.
- Trial name
- NCT04811690
- Testing
- front-of-package modification
- Where
- United States
- Volunteers
- 5,028 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Vascular Stiffness, Inflammation
Anthocyanin-rich Blackcurrant and Vascular Function
Regular consumption of fruits and vegetables may improve human health and reduce the risk of chronic diseases, such as heart disease, certain cancers and type 2 diabetes, but the active components and the underlying mechanisms…
- Trial name
- NCT02459756
- Testing
- Beverage: Spray dried blackcurrant powder dissolved in water
- Where
- United Kingdom
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Reading
Asthma
Orthomolecular Therapy and Asthma in Children
The purpose of this study is 1. To pilot the research methodology for a randomized trial on an orthomolecular treatment regime versus placebo as add-on therapy for children with asthma; 2.
- Trial name
- NCT00672529
- Where
- Canada
- Volunteers
- 90 people
- Sponsor
- Canadian Institute of Natural and Integrative Medicine
Lateral Epicondylitis, Tennis Elbow
Efficacy of Vitamin C Supplement vs Spinal Manipulation to Treatment in Lateral Epicondylitis
A randomized clinical trial will be conducted. 130 subjects diagnosed with lateral epicondylitis will be studied. 3 intervention groups will be formed.
- Trial name
- NCT04445727
- Testing
- Vitamin C, spinal manipulation, Transcutaneous electrical nerve stimulation (TENS)
- Where
- Spain
- Volunteers
- 130 people
- Sponsor
- Universidad Rey Juan Carlos
Necrotic Primary Teeth
Evaluation of Antimicrobial Potency of Garlic Lemon Extract Irrigant Versus Physiological Saline Irrigant
To evaluate the antimicrobial potency of Garlic Lemon extract irrigant versus physiological saline irrigant following partial pulpectomy in primary molars.
- Trial name
- NCT06759766
- Testing
- Garlic-Lemon Extract irrigant, physiological saline
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Cairo University
Bowel Preparation Quality
The Impact of Additional Oral Preparation on the Quality of Bowel Preparation for Colonoscopy
Although adequate bowel preparation is essential for successful colonoscopy, the 23% of patients had shown inadequate bowel preparation.
- Trial name
- NCT02540031
- Testing
- Additional oral preparation (3L of PEG+Asc, "Coolprep®"), Standard oral preparation (2L of PEG+Asc, "Coolprep®")
- Where
- South Korea
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Kyungpook National University Hospital
Urinary Tract Infections, Recurrent
Effect of Hyaluronic Acid Oral Supplementation on Sexual and Urinary Symptoms of Women With Recurrent Urinary Tract Infections
Uncomplicated urinary tract infections (UTI) are one of the most common bacterial infections globally, causing a significant proportion of medical consultations in primary and outpatient settings.
- Trial name
- JalUrol (NCT06268483)
- Testing
- HA 100 mg, CS 400 mg, N-Acetylglucosamine 200 mg and vitamin C 80 mg + cranberry, D-mannose, propolis extract, tumeric and Boswellia, cranberry, D-mannose, propolis extract, tumeric and Boswellia
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Iron-deficiency
Measuring Dietary Iron Absorption From Edible Insects and Assessing the Effect of Chitin Content on Iron Bioavailability (Study 2)
Due to the growing world population, there is a need to develop viable ecological and nutritional alternatives to animal food products.
- Trial name
- Sustironable2 (NCT05328141)
- Testing
- Bread and butter, X.gideon, X.gideon with ascorbic acid
- Where
- Switzerland
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Adherence, Medication
Intervention for Multivitamin Adherence on Bariatric Patients
This project has a parallel randomized controlled experimental design since within the methodology there will be a control of the conditions under study, that is, the selection of subjects, the way the treatment will be…
- Trial name
- CDIPMABP (NCT04612088)
- Testing
- Cognitive Dissonance
- Where
- Mexico
- Volunteers
- 34 people
- Sponsor
- Universidad Autonoma de Baja California
Catheter-Associated Urinary Tract Infection, Ascorbic Acid
Vitamin C for the Prevention of UTI in Women Who Undergo Elective GYN Surgeries
This open-label randomized trial aims at assessing the role of Vitamin C pills in the prevention of catheter-associated urinary tract infections in women undergoing elective gynecological surgeries.
- Trial name
- NCT03800667
- Testing
- Ascorbic Acid 1000 MG
- Where
- Lebanon
- Sponsor
- American University of Beirut Medical Center
COVID-19 Pneumonia
Efficacy and Safety of Oral Immunotherapy With GcMAF in Hospitalized Patients With COVID-19 Pneumonia
As of August 16, 2020, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been responsible for more than 21 294 000 infections and about 760 000 deaths worldwide.
- Trial name
- COral-MAF1 (NCT04845971)
- Testing
- Saisei Maf capsules
- Where
- Italy
- Volunteers
- 97 people
- Sponsor
- Dr. Spadera Lucrezia
COVID-19, SARS-CoV-2
Treatment for COVID-19 in High-Risk Adult Outpatients
This is a randomized trial for the treatment of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in high-risk adults not requiring hospital admission.The overarching goal of this study is to assess the…
- Trial name
- NCT04354428
- Testing
- Ascorbic Acid, Hydroxychloroquine Sulfate, Azithromycin
- Where
- 6 sites in United States
- Volunteers
- 289 people, healthy volunteers welcome
- Sponsor
- University of Washington
Prehypertension, Hypertension
Nebivolol and Endothelial Regulation of Fibrinolysis (NERF)
The investigators hypothesize that nebivolol will improve endothelial t-PA release in adult humans with elevated blood pressure to a greater extent than either metoprolol or placebo.
- Trial name
- NCT01595516
- Testing
- Nebivolol, Metoprolol, Bradykinin
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Boulder
Colonoscopy
A Phase III Trial to Assess the Efficacy, Acceptability and Safety of Moviprep® Versus a 4L PEG+E Standard Solution
The study was carried out as a randomised, single-blind, active-controlled, multi-centric, phase III study with two parallel treatment groups.
- Trial name
- NCT00389233
- Testing
- Macrogol3350 NA sulphate NACl KCl ascorbic acid NA ascorbate, Macrogol3350 Na sulphate Na bicarbonate NaCl KCl
- Where
- 12 sites in Germany
- Volunteers
- 360 people
- Sponsor
- Norgine
Hepatocellular Carcinoma
A Phase II/III Clinical Study on Inhibitory Effects of E0167 on Recurrence of Hepatocellular Carcinoma
The purpose of this study is to determine the superiority of inhibitory effects and safety of Menatetrenone (E0167) on recurrence in patients with hepatocellular carcinoma.
- Trial name
- NCT00165633
- Testing
- Menatetrenone
- Where
- 30 sites in Japan
- Volunteers
- 540 people
- Sponsor
- Eisai Limited
Formula Milk, Breast Milk Collection
Metabolomic Profile in Breastfed Late Preterm Infants
Exclusive breast milk is recommended from birth to 6 months of life to promote the development of a balanced intestinal microbiota.
- Conditions
- Formula Milk, Breast Milk Collection, Postbiotic Supplemented Formula Milk
- Trial name
- NCT06052592
- Testing
- Milk
- Where
- 2 sites in Italy
- Volunteers
- 54 people
- Sponsor
- Ospedale Buon Consiglio Fatebenefratelli
Osteoporosis
Growth Hormone Therapy and Bone Quality in Pediatric Osteoporosis
The primary objective of this study is to test the hypothesis that growth hormone, administered daily by subcutaneous injection for 2 years will result in a significantly greater BMD Z-score over optimal standard therapy.
- Trial name
- NCT00757393
- Testing
- Vitamin D + Calcium + Exercise program, Vitamin D + Calcium + Exercise program + Humatrope
- Where
- Canada
- Volunteers
- 21 people
- Sponsor
- The Hospital for Sick Children
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