Clinical trials: conventional surgery, completed
Anterior Cruciate Ligament Injury, Ligament Rupture
ACL Versus ALL + ACL Study
The aim of the study is to show a reduction of a re-rupture rate with an ACL (antero crusader ligament) + ALL (anterolateral ligament) combined technique compared to a classical Kenneth-Jones ACL (antero crusader ligament)…
- Trial name
- NCT03740022
- Testing
- ACL plasty, ACL + ALL plasty
- Where
- France
- Volunteers
- 592 people
- Sponsor
- Ascopharm Groupe Novasco
Mechanical Ventilation Complication, Thoracic Surgery
The Effect of Recruitment Maneuver With Protective Ventilation During Thoracic Surgery
The purpose of this study is to determine if a recruitment maneuver combined with protective ventilatory strategy could reduce the pulmonary and systemic inflammatory responses to one-lung ventilation during thoracic surgery.
- Conditions
- Mechanical Ventilation Complication, Thoracic Surgery, Inflammation
- Trial name
- NCT01630395
- Testing
- protective ventilation, Recruitment maneuver combined with protective ventilation
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Seoul National University Hospital
Anesthesia
The Effect of Combined Bilateral Infraorbital and Infratrochlear Nerve Block in Nasal Surgeries
The aim of the study is to assess the efficacy of adding a pre-emptive combined bilateral infraorbital and infratrochlear nerve blocks with bupivacaine 0.25% in decreasing intraoperative and postoperative analgesics consumption…
- Trial name
- NCT06174675
- Testing
- combined bilateral infraorbital and infratrochlear nerve blocks
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
Surgical Hemorrhage
A Phase III Study of Hemofence for Hemostasis in Patients With Uncontrolled Exudative Hemorrhage During Spinal Or Orthopedic Surgery
This Phase 3 study was conducted to evaluated the efficacy and safety of Hemofence compared with Floseal Hemostatic Matrix in patients undergoing spinal or orthopedic surgery who required hemostasis for exudative bleeding that…
- Trial name
- NCT07824024
- Testing
- Hemofence, Floseal hemostatic matrix
- Where
- 3 sites in South Korea
- Volunteers
- 172 people
- Sponsor
- BMI Korea
Fallopian Tube Cancer, Ovarian Cancer
Chemotherapy Plus Surgery in Treating Patients With Stage III or Stage IV Ovarian, Peritoneal, or Fallopian Tube Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining surgery with chemotherapy may kill more tumor cells.
- Conditions
- Fallopian Tube Cancer, Ovarian Cancer, Primary Peritoneal Cavity Cancer
- Trial name
- NCT00003636
- Testing
- carboplatin, cisplatin, conventional surgery
- Where
- 65 sites in Argentina, Austria and 13 more
- Volunteers
- 704 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Knee Arthritis
Knee Arthroplasty Performed With Conventional and Customized Instrumentation
The main purpose of this study is to determine whether the surgical time required for primary total knee arthroplasty is significantly less when performed with Customized Patient Instrumentation (CPI) than with conventional…
- Trial name
- CPI (NCT01124305)
- Testing
- Customized Patient Instrumentation, Traditional Instrumentation
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Anderson Orthopaedic Research Institute
Renal Cell Carcinoma, Circulating Tumor Cell
Circulating Tumor Cell Reducing No-touch Nephrectomy
This study will study circulating tumor cell (CTC) release during laparoscopic radical nephrectomy (LRN) for RCC. The main objective is to determine if CTC release can be reduced during RN by using a no-touch technique, with an…
- Trial name
- CITO-CERENE (NCT05070637)
- Testing
- No-touch laparoscopic radical nephrectomy, Conventional laparoscopic radical nephrectomy, Laparoscopic total nephrectomy control arm
- Where
- Portugal
- Volunteers
- 44 people
- Sponsor
- Hospital de Santa Maria, Portugal
Orthodontic Appliance Complication
Evaluation of Maxillary Buccal Miniscrew Insertion Using Digital Guides
This randomized split-mouth clinical trial aims to compare the accuracy and clinical outcomes of CAD/CAM 3D-printed surgical guides with the conventional free-hand technique for orthodontic miniscrew placement in the posterior…
- Trial name
- NCT07698730
- Testing
- CAD/CAM 3D-Printed Surgical Guide, Free-Hand Orthodontic Miniscrew Placement
- Where
- Vietnam
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Can Tho University of Medicine and Pharmacy
Pain, Postoperative, Post Operative Swelling
Effect Of Autologous Platelet Rich Fibrin On Post-Operative Complications And Healing Following The Extraction
As post-operative pain, infection inflammation and infections are the main complications after the surgical extraction of the lower third molar the aim of this study is to compare the healing effects of PRF administered…
- Conditions
- Pain, Postoperative, Post Operative Swelling, Trismus, Soft Tissue Healing
- Trial name
- PRF (NCT06609967)
- Testing
- application of PRF, application of conventional surgicel
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Osteoarthritis, Knee
Persona TKA With iASSIST Knee System and iASSIST Knee System
The purpose of this study is to compare the accuracy of knee component alignment between patients operated with iASSIST Knee (Investigational group) versus patients operated without iASSIST Knee (Control group) using the same…
- Trial name
- NCT03227692
- Testing
- Persona Knee System, Total Knee Arthroplasty, iAssist Knee
- Where
- 3 sites in Japan
- Volunteers
- 93 people
- Sponsor
- Zimmer Biomet
Frenulum; Hypertrophy, Lip
Comparison of Diode Laser and Scalpel Frenectomy With or Without Photobiomodulation
This randomized controlled clinical trial aimed to compare postoperative outcames of conventional scalpel frenectomy and diode laser frenectomy with or without adjunctive photobiomodulation therapy.
- Trial name
- NCT07465536
- Testing
- Scalpel Frenectomy, Diode Laser Frenectomy, Photobiomodulation Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people
- Sponsor
- Kocaeli University
Adenocarcinoma of the Gastroesophageal Junction, Esophageal Cancer
Panitumumab, Docetaxel, Cisplatin, Radiation Therapy, and Surgery in Treating Patients With Newly Diagnosed, Locally Advanced Esophageal Cancer or Cancer of the Gastroesophageal Junction
RATIONALE: Monoclonal antibodies, such as panitumumab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread.
- Trial name
- NCT00757172
- Testing
- panitumumab, cisplatin, docetaxel
- Where
- 21 sites in United States
- Volunteers
- 70 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Colorectal Cancer
Eniluracil and Surgery in Treating Patients With Primary or Metastatic Colorectal Cancer
RATIONALE: Eniluracil may increase the effectiveness of chemotherapy by blocking tumor enzymes that break down chemotherapy drugs.
- Trial name
- NCT00004195
- Testing
- eniluracil, conventional colon surgery
- Volunteers
- 28 people
- Sponsor
- University of Alabama at Birmingham
Intestinal Obstruction, Postoperative Complications
Impact of Interactive Video Health Intervention on Quality of Life After Bowel Obstruction Surgery
Objective: To investigate the multidimensional effects of an interactive video health intervention on the quality of life and clinical rehabilitation indicators of patients with early postoperative bowel obstruction.
- Trial name
- NCT07258017
- Testing
- Conventional care, Interactive Video Health Intervention
- Where
- China
- Volunteers
- 462 people
- Sponsor
- Changsha Fourth Hospital
Breast Cancer
AZD2171 and Combination Chemotherapy in Treating Women With Locally Advanced Breast Cancer
RATIONALE: AZD2171 may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor.
- Trial name
- NCT00310089
- Testing
- filgrastim, pegfilgrastim, cediranib maleate
- Where
- 2 sites in United States
- Volunteers
- 33 people
- Sponsor
- National Cancer Institute (NCI)
Crestal Bone Loss
Soft Tissue Esthetic With Autogenous Dentin Chips and Immediate Implantation Versus Conventional Immediate Implantation With Xenograft in Thin Buccal Bone
After tooth extraction, host bone resorption and atrophy of alveolar ridge may be observed. Bone resorption occurs specially in incisors and premolar area of jaw in region of thin buccal bone that may lead to change in contour.
- Trial name
- NCT03544580
- Testing
- immediate implant with dentine chips, conventional immediate implant
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Cairo University
Adenomyosis
GyneFix IUD Plus LNG-IUS for Adenomyosis
Adenomyosis is a common gynecological condition that can cause menstrual pain, heavy menstrual bleeding, anemia, and reduced quality of life.
- Trial name
- GYNEFIX-AM (NCT07680985)
- Testing
- Indomethacin-GyneFix IUD Plus LNG-IUS, Ring IUD Plus LNG-IUS, LNG-IUS Alone
- Where
- China
- Volunteers
- 270 people
- Sponsor
- Wenzhou People's Hospital
Aortic Valve Disease
Ross for Valve Replacement in AduLts Trial
This study evaluates two methods of aortic heart valve replacement in adults aged 18-60, the Ross procedure versus conventional aortic valve replacement using a biologic or mechanical heart valve.
- Trial name
- REVIVAL (NCT03798782)
- Testing
- Ross procedure, Conventional aortic valve replacement
- Where
- Canada
- Volunteers
- 43 people
- Sponsor
- Population Health Research Institute
Cystic Fibrosis Liver Disease, Portal Hypertension Due to Cystic Fibrosis (Disorder)
Pre-emptive Transjugular Intrahepatic Portosystemic Shunt (TIPS) in Cystic Fibrosis Related Liver Disease
Portal hypertension (PHT) and its sequelae are the most clinically important manifestation in cystic fibrosis related liver disease (CFLD), with end-stage liver failure as a late and rare manifestation.
- Conditions
- Cystic Fibrosis Liver Disease, Portal Hypertension Due to Cystic Fibrosis (Disorder), Portal Hypertension, Noncirrhotic
- Trial name
- NCT05037643
- Testing
- TIPS
- Volunteers
- 5 people
- Sponsor
- University Hospital, Ghent
Pediatric Disorder, Pneumothorax, Spontaneous
Single Site Thoracic Surgery for Pediatric Pneumothorax
Video-Assisted Thoracoscopic Surgery (VATS) has become a standard of care in adults, pediatric surgeons have been slower to undertake this approach. There are limitations for working in children.
- Conditions
- Pediatric Disorder, Pneumothorax, Spontaneous, Thoracic Diseases, Thoracic Surgery
- Trial name
- NCT05034640
- Testing
- Conventional multiport thoracoscopic surgery, Single port site thoracoscopic surgery
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Loma Linda University
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