Clinical trials: conventional surgery, completed
Osteoarthritis, Knee, Joint Disease
Matched Pair Study - Kinematic Vs Mechanical Alignment
The aim of this study is to evaluate postoperative knee function after total knee arthroplasty performed according to the anatomical alignment and compare these results to those of a matched historical cohort of patients operated…
- Trial name
- NCT03446391
- Testing
- Kinematic alignment, Mechanical alignment, GMK Sphere®
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Medacta International SA
Cholelithiasis
Comparison of "Pick'n Roll" Single-incision Laparoscopic Cholecystectomy Technique, and Laparoscopic Cholecystectomy
Cholecystectomy is one of the most common operation performed by general surgeons. Since, first video-laparoscopic cholecystectomy in 1987, laparoscopic cholecystectomy (LC) has become the gold standard treatment for benign…
- Trial name
- NCT02149797
- Testing
- Four port laparoscopic cholecystectomy, SILC-Pick'n roll-Beginning (group I), SILC-Pick'n roll-Experienced (group II)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Samsun Education and Research Hospital
Erector Spinae Plane Block
Effectiveness of Bilateral Ultrasound-Guided Erector Spinae Plane Block
The proposed mechanism of action of the ESPB is via blockade of the dorsal and ventral rami of the spinal nerves and sympathetic nerve fibers.
- Trial name
- NCT04110210
- Testing
- Bilateral Ultrasound-Guided Erector Spinae Plane Block, Morphine Consumption
- Where
- Egypt
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Cairo University
Global Warming Effect of Nitrous Oxide
Global Warming Impact of Nitrous Oxide
Environmental hazards of human activity are a topic of present day world, global warming being one of the leading concerns. Gases that contribute to this are greenhouse gases.
- Trial name
- NCT05430750
- Testing
- Nitrous oxide, Sevoflurane
- Where
- India
- Volunteers
- 102 people
- Sponsor
- Sir Ganga Ram Hospital
Type 1 Diabetes
Closed-loop Control of Glucose Levels After Meal Intake in Adults With Type 1 Diabetes
Closed-loop strategy is composed of three components: glucose sensor to read glucose levels, insulin pump to infuse insulin and a dosing mathematical algorithm to decide on the required insulin dosage based on the sensor's…
- Trial name
- NCT01930097
- Testing
- 14 hours intervention
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- Institut de Recherches Cliniques de Montreal
Hemorrhage
Effectiveness of BioFoam® Surgical Matrix to Improve Hemostasis During Liver Resection
The present randomized controlled trial evaluates the efficacy and safety of BioFoam® Surgical Matrix in patients undergoing elective liver resection.
- Trial name
- BioFoam (NCT02612220)
- Testing
- BioFoam® Surgical Matrix, Conservative hemostasis
- Where
- Germany
- Volunteers
- 101 people
- Sponsor
- Technische Universität Dresden
Hemorrhoidal Disease
Upper Rectal Artery Embolization in the Treatment of Hemorrhoidal Disease
Hemorrhoidal disease diagnosis is based on medical history combined with physical exam and complementary exam. Physical exam should include inspection at exertion, digital rectal exam ,and anoscopy.
- Trial name
- NCT03402282
- Testing
- embolization, surgical repair
- Where
- Brazil
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Hospital Israelita Albert Einstein
Opioid Use, Pain, Postoperative
Erector Spinae Plane Block Versus Conventional Analgesia in Complex Spine Surgery
Enhanced recovery pathways (ERPs) emphasize evidence-based, multimodal anesthetic and analgesic choices to minimize opioid consumption while providing adequate pain control after surgery.
- Trial name
- ESPB-Spine (NCT04156581)
- Testing
- Bupivacaine, Dexamethasone, Saline
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Hospital for Special Surgery, New York
Postoperative Sore Throat, Endotracheal Intubation
Scheduled Endotracheal Tube Cuff Pressure Management and Postoperative Sore Throat
This randomized controlled trial evaluated whether scheduled measurement and adjustment of endotracheal tube cuff pressure using a handheld manometer could reduce postoperative sore throat in adults undergoing elective surgery…
- Trial name
- NCT07842081
- Testing
- Handheld Endotracheal Tube Cuff Manometer, Pilot-Balloon Palpation
- Where
- Turkey (Türkiye)
- Volunteers
- 126 people
- Sponsor
- Hitit University
Gastric Cancer, Complement Component Deficiency
The Predictive Value of Complement C3 in Patients With Advanced Gastric Cancer
This study is designed to investigate whether complement C3 depletion is associated with poor short-term outcomes in postoperative patients with gastric cancer.
- Conditions
- Gastric Cancer, Complement Component Deficiency, Surgery
- Trial name
- NCT02425930
- Testing
- gastrectomy plus D2 lymphadenectomy, S-1+Oxaliplatin
- Where
- China
- Volunteers
- 85 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Hand Injuries, Tendon Injuries
Randomized Trial of Active vs Passive Splinting for Extensor Tendon Injuries in Zones IV to VI
This study compares two methods of post-operative immobilization after surgical repair (tenorrhaphy) of extensor tendons in the fingers.
- Trial name
- NCT06950268
- Testing
- ICAMS Splinting Protocol, Classic Plaster Immobilization
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Fundacin Biomedica Galicia Sur
Single Tooth Lost, Partially Edentulous Maxilla
Accuracy of Trephination-based Versus Drilling-based Guided Dental Implant Placement
This study will be initiated to compare the accuracy of implant placement using the guided trephination drilling protocol and the guided conventional drilling protocol.
- Trial name
- NCT05295082
- Testing
- guided trephination-based drilling protocol, guided Conventional drilling-based protocol
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Mohammed Ramadan
Gastrointestinal Stromal Tumor, Metastatic Cancer
Surgery in Treating Patients With Liver Metastasis From a Gastrointestinal Stromal Tumor
RATIONALE: Surgery may be an effective treatment for liver metastasis from a gastrointestinal stromal tumor. PURPOSE: This phase II trial is studying how well surgery works in treating patients with liver metastasis from a…
- Trial name
- GISTs (NCT00769782)
- Testing
- therapeutic conventional surgery
- Where
- 37 sites in Japan
- Volunteers
- 6 people
- Sponsor
- Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan
Inflammatory Breast Cancer, Stage II Breast Cancer
Tipifarnib, Doxorubicin, and Cyclophosphamide in Treating Women With Locally Advanced Breast Cancer
Drugs used in chemotherapy, such as doxorubicin and cyclophosphamide, work in different ways to stop tumor cells from dividing so they stop growing or die.
- Conditions
- Inflammatory Breast Cancer, Stage II Breast Cancer, Stage IIIA Breast Cancer, Stage IIIB Breast Cancer
- Trial name
- NCT00049114
- Testing
- doxorubicin hydrochloride, cyclophosphamide, tipifarnib
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- National Cancer Institute (NCI)
Knee Replacement, Total Knee Arthroplasty
Trial of Liposomal Bupivacaine for TKA
Total knee arthroplasty (TKA), also known as a knee replacement, is a procedure performed to reduce severe pain and improve function of the joint.
- Conditions
- Knee Replacement, Total Knee Arthroplasty, Post-Operative Pain
- Trial name
- NCT05635916
- Testing
- Liposomal bupivacaine, Bupivacaine
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Northern Light Mercy Hospital
Leukemia
Stem Cell Transplantation Compared With Standard Chemotherapy in Treating Patients With Acute Lymphoblastic Leukemia in First Remission
RATIONALE: Drugs used in chemotherapy work in different ways to stop cancer cells from dividing so they stop growing or die. Combining chemotherapy with allogeneic or autologous stem cell transplantation may allow the doctor to…
- Trial name
- NCT00002514
- Testing
- sargramostim, asparaginase, cyclophosphamide
- Where
- 94 sites in United States
- Volunteers
- 1,929 people
- Sponsor
- Eastern Cooperative Oncology Group
Impacted Mandibular Third Molar, Pain
Ultrasonic vs Rotary Instruments in Impacted Mandibular Third Molar Surgery: Clinical and Salivary CRP Outcomes
In the surgical removal of impacted mandibular third molars, ultrasonic surgical devices (piezosurgery) have been introduced with the expectation of reducing postoperative complications such as swelling, pain, and trismus…
- Conditions
- Impacted Mandibular Third Molar, Pain, Swelling, Trismus
- Trial name
- PiezoCRP (NCT07196904)
- Testing
- Ultrasonic Device (Piezosurgery), Conventional rotary instruments
- Where
- Vietnam
- Volunteers
- 22 people
- Sponsor
- Le Huynh Thien An
Pain, Postoperative
Ultrasound-guided Dual TAP Block: Magnetic Resonance (MR) Evaluation of the Distribution of Local Anesthetic
Using Magnetic resonance (MR) scanning and ultrasonography the investigators wish to investigate, in what way a known volume of local anesthetic injectate will be distributed in the transverse abdominis plane (TAP) in young…
- Trial name
- NCT01305603
- Testing
- Bupivacaine, Injection
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Cataract, Nursing Caries
Effects of Music and Stress Ball Application on Patients During Cataract Surgery
Cataract is one of the leading causes of preventable blindness in the world and in Türkiye. Cataract surgery is one of the most frequently performed and most reliable surgeries for eye diseases.
- Trial name
- NCT06555770
- Testing
- Music intervention, Stress ball
- Where
- Turkey (Türkiye)
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Partially Edentulous Maxilla, Mandible
Accuracy of Scannable Healing Abutments for Implant Impressions
This prospective controlled clinical trial evaluates the three-dimensional positional accuracy of implant-level impressions obtained using scannable healing abutments compared with conventional open-tray and closed-tray…
- Trial name
- NCT07393269
- Testing
- Digital implant impression using scannable healing abutments, Open-tray implant impression, Closed-tray implant impression
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Sherif Aly Sadek
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