Clinical trials: sponsored by Capital Medical University
Ischemic Stroke, Atrial Fibrillation
Timing of Anticoagulation After Emergency Endovascular Therapy for Acute Ischemic Stroke With Atrial Fibrillation 2
This study evaluates the safety and efficacy of early versus delayed initiation of direct oral anticoagulants (DOACs) in patients with acute ischemic stroke related to atrial fibrillation who develop hemorrhagic transformation…
- Trial name
- TIMERS-2 (NCT07139314)
- Testing
- Early anticoagulation, Delayed anticoagulation
- Where
- 37 sites in China
- Volunteers
- 240 people
- Sponsor
- Capital Medical University
Ischemic Stroke, Alzheimer Disease (AD)
Cerebrospinal Fluid Mitochondrial Biomarkers in Ischemic Stroke and Alzheimer Disease
This prospective observational study aims to investigate cerebrospinal fluid mitochondrial biomarkers in patients with ischemic stroke and Alzheimer disease controls who undergo diagnostic lumbar puncture for clinical indications…
- Trial name
- NCT07600996
- Testing
- Cerebrospinal Fluid Flow Cytometry
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Capital Medical University
Cerebral Venous Thrombosis
Anticoagulation Combined With Tocilizumab for Interleukin-6 Receptor Inhibition in Acute Cerebral Venous Thrombosis
This study aims to evaluate the efficacy and safety of tocilizumab, an interleukin-6 (IL-6) receptor antagonist, combined with standard anticoagulant therapy compared with standard anticoagulant therapy alone in patients with…
- Trial name
- NCT07801638
- Testing
- Tocilizumab, Standard Treatment
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Capital Medical University
Venous Access, Endovascular Procedures
Postprocedural Bed-Rest Strategies After Transfemoral Venous Interventions
The goal of this clinical trial is to determine whether shorter periods of immobilization and bed rest after femoral venous interventional procedures can be safely used in adult patients undergoing peripheral venous interventions…
- Conditions
- Venous Access, Endovascular Procedures, Early Ambulation, Femoral Vein
- Trial name
- TVI-COMFORT (NCT07807787)
- Testing
- 2-hour Immobilization and Bed Rest, 4-hour Immobilization and Bed Rest, 8-hour Immobilization and Bed Rest
- Volunteers
- 1,550 people
- Sponsor
- Capital Medical University
Relevant Conditions Identification
Improving the Reliability of LLMs as Medical Assistants for the General Public
This study will evaluate whether three-minute six-dimensions education(3M-6D education) can improve the reliability of large language models as medical assistants for the general public.
- Trial name
- LAMP-1 (NCT07651280)
- Testing
- three minutes six dimensions education, ChatGPT, Gemini
- Where
- China
- Volunteers
- 527 people, healthy volunteers welcome
- Sponsor
- Capital Medical University
Influenza Infection
Efficacy and Safety of Inhaled Peramivir Solution for the Treatment of Adults With Uncomplicated Influenza
This multicenter, randomized, double-blind, placebo-controlled, parallel-group Phase 3 study will evaluate the efficacy and safety of peramivir inhalation solution in adults with uncomplicated influenza.
- Trial name
- NCT07791251
- Testing
- Peramivir Inhalation Solution
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Capital Medical University
Ischemic Stroke, Acute
Artificial Intelligence Support for Stroke
This study investigates whether an AI-assisted decision support tool, compared with standard care, increases the proportion of acute ischemic stroke patients receiving intravenous thrombolysis within 24 hours of symptom onset at…
- Trial name
- NCT07785492
- Testing
- AI-assisted thrombolysis decision support
- Where
- China
- Volunteers
- 516 people
- Sponsor
- Capital Medical University
Acute Ischemic Stroke
Anisodine Hydrobromide for Patients With Acute Ischemic Stroke Undergoing Endovascular Therapy (HEAL)
This study is an investigator-initiated Phase 1b clinical trial employing an open-label, non-randomized, dose-escalation design.
- Trial name
- HEAL (NCT07513233)
- Testing
- Anisodine Hydrobromide
- Where
- 10 sites in China
- Volunteers
- 92 people
- Sponsor
- Capital Medical University
Allergic Rhinitis, Rhinitis, Allergic
AI-Guided Ultrasound Needling of Xinwu Point for Allergic Rhinitis
This study evaluated a new way to perform acupuncture at a deep point called the Xinwu point (sphenopalatine ganglion) for allergic rhinitis (hay fever-like nasal allergy).
- Trial name
- NCT07778537
- Testing
- AI-guided Xinwu-point acupuncture, Blind Xinwu-point acupuncture
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Daxing Teaching Hospital, Capital Medical University
Intracranial Arterial Stenosis
Intracranial Arterial Stenosis in Young Patients
The goal of this study is to evaluate the characteristic of intracranial arterial stenosis among young patients.
- Trial name
- ICAS-Young (NCT05844176)
- Testing
- Routine clinical treatment
- Where
- 4 sites in China
- Volunteers
- 500 people
- Sponsor
- Capital Medical University
Acute Ischemic Stroke
Intra-arterial Selective Hypothermic Magnesium Sulfate Infusion in Combination With Endovascular Thrombectomy in Acute Ischemic Stroke
The primary objective of this study is to estimate the safety and effectiveness of selective intra-arterial hypothermic magnesium sulfate infusion after endovascular thrombectomy in patients with acute ischemic stroke.
- Trial name
- ICE-MAG (NCT07163299)
- Testing
- Endovascular thrombectomy combination with selective intra-arterial hypothermic magnesium sulfate infusion (350 ml)., Endovascular thrombectomy combination with selective intra-arterial hypothermic magnesium sulfate infusion (500 ml)., Endovascular thrombectomy combination with selective intra-arterial hypothermic magnesium sulfate infusion (650 ml).
- Where
- China
- Volunteers
- 42 people
- Sponsor
- Capital Medical University
Mechanical Ventilation
Clinical Application of the Effect of Respiratory Muscles Electrical Stimulation on Weaning in Patients With Difficult Weaning of the Mechanical Ventilation
This trial evaluates whether transcutaneous diaphragmatic/phrenic nerve stimulation (TEDS), abdominal functional electrical stimulation (abFES), or their combination, accelerates and improves the quality of weaning from prolonged…
- Trial name
- NCT07199036
- Testing
- TEDS (Transcutaneous Diaphragmatic/Phrenic Nerve Stimulation), abFES (Functional Electrical Stimulation of Abdominal Muscles)
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Capital Medical University
Treatment-Resistant Depression, Depressive Disorder
Stereotactic Radiotherapy Treatment for Treatment-Resistant Depression
This study is an clinical trial aimed at evaluating the effectiveness and safety of stereotactic radiotherapy for treatment-resistant depression
- Trial name
- NCT07274917
- Testing
- ZAP-X
- Where
- China
- Volunteers
- 9 people
- Sponsor
- Capital Medical University
Nervous System Diseases
Domain-Specific Large Language Model Assistance for Emergency Neurological Diagnosis and Treatment（DEMAND）
This study will evaluate whether Xuanwu-NeuroAid 2.0, a large language model for emergency neurology, can improve 30-day diagnostic quality in adults with acute neurological symptoms.
- Trial name
- NCT07626229
- Testing
- Xuanwu-NeuroAid 2.0
- Where
- 3 sites in China
- Volunteers
- 1,381 people
- Sponsor
- Capital Medical University
Major Depressive Disorder (MDD)
Context-Guided Personalized iTBS for Depression
The goal of this randomized clinical trial is to learn whether context-guided personalized intermittent theta burst stimulation (iTBS) works better than standard iTBS for adults with major depressive disorder.
- Trial name
- NCT07743398
- Testing
- Context-Guided Personalized Intermittent Theta Burst Stimulation, Standard Left DLPFC Intermittent Theta Burst Stimulation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Capital Medical University
Delayed Tracheostoma Healing Following Decannulation in Long-term Tracheostomy Patients
Predictive Model for Stoma Healing After Tracheostomy Decannulation in Patients With Prolonged Tracheostomy
Prolonged tracheostomy is prone to induce chronic airway mucosal injury and tracheal cartilage degeneration, which not only elevates the risks of post-decannulation complications such as persistent fistula non-healing, airway…
- Trial name
- STOMA-PRED (NCT07747844)
- Testing
- No intervention
- Where
- China
- Volunteers
- 219 people
- Sponsor
- Capital Medical University
Ischemic Stroke, Atrial Fibrillation
Timing of Anticoagulation After Emergency Endovascular Therapy for Acute Ischemic Stroke With Atrial Fibrillation
This study evaluates the safety and efficacy of early versus delayed initiation of direct oral anticoagulants (DOACs) in patients with acute ischemic stroke related to atrial fibrillation after emergency endovascular therapy…
- Trial name
- TIMERS-1 (NCT07139301)
- Testing
- Early anticoagulation, Delayed anticoagulation
- Where
- 40 sites in China
- Volunteers
- 438 people
- Sponsor
- Capital Medical University
Acute Ischemic Stroke
Urokinase for Thrombolysis in Acute Ischemic Stroke
According to the Chinese Guidelines for the Diagnosis and Treatment of Ischemic Stroke, intravenous thrombolysis with urokinase, administered at doses of 1-1.5 million IU within 6 hours of symptom onset, has been shown to be both…
- Trial name
- NCT07047326
- Testing
- Urokinase thrombolysis
- Where
- 2 sites in China
- Volunteers
- 24 people
- Sponsor
- Capital Medical University
Obesity, Mild Cognitive Impairment
Effects of Functional Oils on Obesity With Mild Cognitive Impairment
The purpose of this study is to investigate the effects of diacylglycerol (DAG) oil on obesity accompanied by mild cognitive impairment (MCI).
- Trial name
- NCT07690384
- Testing
- Rapeseed Oil (RSO), Diacylglycerol Oil (DAG Oil)
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Capital Medical University
Acute Ischemic Stroke, Hypothermia
Safety and Efficacy of Selective Intra-Arterial Cooling Infusion Combined With EVT in Acute Ischemic Stroke
This is a multicenter, randomized, controlled, subject- and assessor-blinded clinical trial. The research objective is to evaluate the safety and efficacy of selective intra-arterial cooling infusion combined with endovascular…
- Trial name
- FOCUS (NCT06485427)
- Testing
- Selective Intra-arterial Cooling Infusion (IA-SCI)
- Where
- 12 sites in China
- Volunteers
- 258 people
- Sponsor
- Beijing Shijitan Hospital, Capital Medical University