Clinical trials: sponsored by Göteborg University
Neuropathic Pain
Spinal Cord Stimulation and Physiotherapy for Treatment of Neuropathic Pain
The study evaluates the combined effect of optimized pharmacological treatment, spinal cord stimulation and physiotherapy on pain relief, health-related quality of life and physical function in patients with neuropathic pain.
- Trial name
- SCS-PHYSIO (NCT03740763)
- Testing
- Spinal Cord Stimulation (SCS), Physiotherapy
- Where
- Sweden
- Volunteers
- 48 people
- Sponsor
- Göteborg University
Endometriosis-related Pain
Transcutaneous Electrical Nerve Stimulation for Endometriosis-related Chronic Pain
The study evaluates the effect of TENS (transcutaneous electrical nerve stimulation) as add-on treatment compared with conventional analgesic treatment in patients with endometriosis-related chronic pain.
- Trial name
- NCT05152264
- Testing
- Transcutaneous electrical nerve stimulation (TENS), Conventional analgesic treatment
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Göteborg University
Abdominal Aortic Aneurysms (AAA)
Effect of Nurse-led Education on Health, Quality of Life and Sexual Health
The main hypothesis is that a nurse-led education provided to patients who received endovascular treatment due to enlarged abdominal aorta would present a difference in perceived health, quality of life and sexual health.
- Trial name
- NCT06986252
- Testing
- Consultation
- Volunteers
- 51 people
- Sponsor
- Göteborg University
Pain, Postoperative
Effective Postoperative Pain Relief After Laparoscopic Cholecystectomy With TENS
The study evaluates the effect of TENS (transcutaneous electrical nerve stimulation) treatment for first line of treatment compared with conventional treatment with opioids on pain relief and time spent time in the…
- Trial name
- NCT04114149
- Testing
- TENS (transcutaneous electrical nerve stimulation), iv opioid
- Where
- Sweden
- Volunteers
- 166 people
- Sponsor
- Göteborg University
Volunteers
Cardiometabolic Health and Inflammatory Resolution
The aim of this study is to determine how inflammatory resolution impacts cardiometabolic health and disease in subjects that are either lean (18.5-24.9 kg/m2), overweight (25.0-29.9 kg/m2) or obese (>30.0 kg/m2).
- Trial name
- REX (NCT04256330)
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Göteborg University
Obese
Adipose Inflammation and Diabetes (FAB)
The study investigates whether the addition of resolution molecules can inhibit inflammation and insulin resistance in human tissue taken from obese individuals, and whether the results of these studies correlate with…
- Trial name
- FAB (NCT04255264)
- Where
- Sweden
- Volunteers
- 18 people
- Sponsor
- Göteborg University
Vascular Diseases, Atherosclerosis
Inflammation in Vascular Disease
Increasing evidence suggests that systemic low-grade inflammation may be a driving force of cardiometabolic complications, such as vascular dysfunction, atherosclerosis and ischemic heart disease.
- Trial name
- REBEL (NCT03732612)
- Where
- Sweden
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Obesity, Morbid, Diabetes Mellitus, Type 2
Jejunal Ketogenesis and Type 2 Diabetes
The goal of this cross-over study in obese subjects is to learn about the common co-morbidity type 2 diabetes and the local formation of ketone bodies.
- Conditions
- Obesity, Morbid, Diabetes Mellitus, Type 2, Intestines, Incretins
- Trial name
- But2 (NCT05767177)
- Testing
- Glucemia following Mixed Meal Test, Enteroscopy - mucosal ketogenic activity as well as glucose transport
- Where
- Sweden
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Arthroplasty, Replacement, Knee
Randomised Total Knee Arthroplasty With Attune S+ or NexGen CR
The primary purpose of this study is to evaluate the clinical performance of the Attune S+ knee primarily based on evaluation with use of Oxford Knee Score. The NexGen TKR will be used as reference standard.
- Trial name
- NexGe (NCT05464641)
- Testing
- Oxford knee score
- Where
- Sweden
- Volunteers
- 150 people
- Sponsor
- Göteborg University
Obesity, Type 2 Diabetes
Sleeve Gastrectomy and Roux-en-Y Gastric Bypass in the Treatment of Type 2 Diabetes Mellitus.
Obesity is a growing epidemic throughout the world and is followed by increasing incidence of type 2 diabetes that accounts for 90-95% of all cases of diabetes.
- Conditions
- Obesity, Type 2 Diabetes, Bariatric Surgery
- Trial name
- CONTROL (NCT01984762)
- Testing
- Roux-en-Y gastric bypass, sleeve gastrectomy
- Where
- Sweden
- Volunteers
- 134 people
- Sponsor
- Göteborg University
Wrist Fracture, Distal Radius Fracture
Use and Meaning of Wrist Orthosis After Distal Radius Fracture
The aim of this study is to investigate the use and meaning of wrist orthosis in everyday occupation after cast removal for adults with non-surgical treatment of distal radius fracture.
- Trial name
- NCT06942546
- Testing
- Wrist orthosis
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Göteborg University
Addison Disease
A Study of Markers of Glucocorticoid Effects in Patients With Addisons Disease (DOSCORT)
DOSCORT is a 2-dose, cross-over study primarily aiming to identify and validate novel biological markers (biomarkers) of glucocorticoid effect in the human body.
- Trial name
- NCT03210545
- Testing
- Betamethasone
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Göteborg University
Obesity, Morbid
BASUN - Risks for Malnutrition, Metabolic Bone Disease and Impaired Oral Health After Obesity Treatment
Weight-reducing obesity surgery (OS) generally gives good results but complications are common; e.g. impaired weight loss, weight regain, bowel pain, diarrhea, vitamin/mineral deficiency, osteoporosis and impaired dental health.
- Trial name
- BASUN (NCT03152617)
- Where
- Sweden
- Volunteers
- 1,400 people
- Sponsor
- Göteborg University
Head and Neck Cancer
Evaluation of an Oral Care Programme for Head and Neck Cancer Patients
This study will evaluate the effect of an intensified oral care programme on prevalence, severity and duration of mucositis in patients undergoing treatment for cancer in the head and neck region.
- Trial name
- NCT03481647
- Testing
- Oral care programme
- Where
- 2 sites in Sweden
- Volunteers
- 150 people
- Sponsor
- Göteborg University
Hepatitis B, Chronic
Discontinuation of Antiviral Therapy as a Strategy to Cure Hepatitis B
Cirrhosis or cancer of the liver caused by hepatitis B virus (HBV) are major global health problems. Chronic HBV infection has become more common in Sweden with immigration.
- Trial name
- STOP-B (NCT05328427)
- Testing
- Stopping
- Where
- Sweden
- Volunteers
- 33 people
- Sponsor
- Göteborg University
Gingival Recession, Localized
Effectiveness of Modified-free Gingival Graft for Treatment of Localized Gingival Recession Defects
The aim of the present study is to evaluate, whether use of the modified free gingival graft (mod-FGG) technique improves treatment outcomes after surgical root coverage at mandibular incisors with gingival recession defects.
- Trial name
- NCT04718545
- Testing
- Mucogingival surgery
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Göteborg University
Heart Failure With Reduced Ejection Fraction
Telemonitored Fast Track Medical Sequencing for Heart Failure With Reduced Ejection Fraction
Research hypothesis: Fast telemonitored medical sequencing in patients with heart failure with reduced ejection fraction (HFrEF) is safe and feasible.
- Trial name
- TELE-FASTER (NCT05637853)
- Testing
- GDMT
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Göteborg University
Frailty, Dependence
Bridging the Gap: Creating a Continuum of Care
Coordination and integration between care settings is essential for the quality of care of frail older patients. An active follow-up by a case manager (CM) after discharge form an acute geriatric hospital ward has the potential…
- Conditions
- Frailty, Dependence, Integrated Care
- Trial name
- NCT06368674
- Testing
- Intervention group Case Manager (CM), Control Group
- Where
- Sweden
- Volunteers
- 150 people
- Sponsor
- Göteborg University
Depressive Disorder, Anxiety Disorders
Cooperation for Primary Care Patients on Sick Leave for CMD: Care Manager and Workplace Intervention - CO-WORK-CARE
This study aims to evaluate whether a convergence dialogue during sick leave, between the employee and the employer, with the Primary Care Centre Rehab Coordinator as discussion leader, leads to reduced sick leave time compared…
- Trial name
- CO-WORK-CARE (NCT03250026)
- Testing
- Workplace convergence dialogue, Care Manager
- Where
- Sweden
- Volunteers
- 349 people
- Sponsor
- Göteborg University
Tick-Bite; Fever, Tick Fever
Fever After Tick Bite Study
The proposed study is a collaboration between Microbiology, SU/Sahlgrenska and the Infectious Diseases clinic at SU/Östra as well as several Infectious Diseases clinics throughout Sweden aiming at improving microbiological…
- Conditions
- Tick-Bite; Fever, Tick Fever, Tick-Borne Diseases, Encephalitis, Tick-Borne
- Trial name
- FATB (NCT03932448)
- Testing
- The proposed study is not interventional.
- Where
- Sweden
- Sponsor
- Göteborg University