Clinical trials: sponsored by Göteborg University
Ventilator-Induced Lung Injury, Ventilatory Failure
"Lung Barometric Measurements in Normal And in Respiratory Distressed Lungs"
Little is known about how lung mechanics are affected during the very early phase after starting mechanical ventilation. Since the conventional method of measuring esophageal pressure is complicated, hard to interpret and…
- Conditions
- Ventilator-Induced Lung Injury, Ventilatory Failure, Ventilator Lung, Ventilation Therapy; Complications
- Trial name
- LUNAR (NCT04484727)
- Testing
- PEEP-step method
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Göteborg University
Colon Cancer
Specific Training After Stoma Surgery
In Sweden, approximately 43,000 people have undergone surgery with ileo-, colo- or urostomy. The most common type of stomy is a sigmoidostomy.
- Trial name
- STASS (NCT04701853)
- Testing
- Specific abdominal muscle training, Usual care
- Where
- 4 sites in Sweden
- Volunteers
- 240 people
- Sponsor
- Göteborg University
Noise Exposure, Sleep Disturbance
Effects of Railway Vibration on Sleep and Disease
This study will investigate the biological mechanisms linking sleep disruption by vibration and noise, and the development of cardiometabolic disease.
- Conditions
- Noise Exposure, Sleep Disturbance, Sleep Hygiene, Metabolic Disturbance
- Trial name
- BioVib (NCT06260254)
- Testing
- Railway noise, Low level railway vibration, Intermediate level railway vibration
- Where
- Sweden
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Gingival Recession, Localized
Effectiveness of Micro Connective Tissue Graft for Treatment of Multiple Adjacent Gingival Recession Defects
The objective of this project is to evaluate 1-year outcomes of treatment of MAGRD using a modified coronally advanced tunnel technique (MCAT) with either conventional CTG (control group) or micro-CTG (test group).
- Trial name
- NCT06030947
- Testing
- Coronally Advanced Flap combined with a Connective Tissue Graft, Coronally Advanced Flap combined with micro Connective Tissue Graft, Division of the Connective Tissue Graft into multiple micro Connective Tissue Grafts
- Where
- United Arab Emirates
- Volunteers
- 30 people
- Sponsor
- Göteborg University
Abdominal Surgery
Mobilisation and Breathing Exercises After Abdominal Surgery at Sahlgrenska University Hospital
The aim of the study is to evaluate the effect of a new care strategy, including earlier and more intensive mobilization and individually adapted breathing exercises, regarding length of stay, recovery, complications and which…
- Trial name
- SUMO (NCT06809036)
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Göteborg University
Frailty, Old Age
Integrating Health Promotion With and for Older People - eHealth
The Integrating Health promotion with and for Older People eHealth (IHOPe) project is expected to contribute vital knowledge on how older peoples capabilities and societal resources can be used in a more efficient way to promote…
- Trial name
- IHOPe (NCT04416815)
- Testing
- Integrating Health promotion with and for Older People - eHealth
- Where
- Sweden
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Gingival Recession, Localized
Effectiveness of Tuberosity Micro Connective Tissue Graft for Treatment of Multiple Adjacent Gingival Recession Defects
The objective of this project is to compare post-operative pain associated with palatal and tuberosity donor sites for micro-CTG, and to evaluate the outcomes in both the donor and recipient sites.
- Trial name
- NCT06650072
- Testing
- modified coronally advanced tunnel technique combined with multiple palatal micro connective tissue grafts, modified coronally advanced tunnel technique combined with multiple tuberosity micro connective tissue grafts
- Volunteers
- 30 people
- Sponsor
- Göteborg University
Musculoskeletal Abnormalities, Hip Injuries
Evaluation of Non-Surgical and Arthroscopic Treatment for Hip Microinstability
Microinstability of the hip joint is an important cause of hip pain and reduced hip function in young and active individuals. Hip microinstability is due to extraphysiologic hip motion and could be secondary to acetabular…
- Trial name
- NCT04934462
- Testing
- physiotherapy, arthroscopy
- Where
- 3 sites in Sweden
- Volunteers
- 26 people
- Sponsor
- Göteborg University
Psychological Distress
Existential Group Treatment for Older Adults (75+) With Psychological Distress in Primary Care
Symptoms of depression and anxiety are common in older adults, and high suicide rates are observed in this age group in Sweden, as in many countries around the globe.
- Trial name
- NCT05503485
- Testing
- Existential group treatment, Supportive telephone calls
- Where
- 7 sites in Sweden
- Volunteers
- 140 people
- Sponsor
- Göteborg University
Traumatic Injuries, Traumatic Injury of Spine
Human Impact Exposure Onboard High-Speed Boats
Operating high-speed boats is dangerous. The purpose of this study is to establish what levels and what characteristics of impact exposure cause injuries.
- Conditions
- Traumatic Injuries, Traumatic Injury of Spine, Traumatic Head Injury
- Trial name
- MASHIEN (NCT05299736)
- Where
- Sweden
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Gestational Diabetes Mellitus
Randomized Controlled Trial Intervention With New Nordic DIet in Women With GestatiOnal Diabetes Mellitus: iNDIGO
The study evaluates whether the New Nordic Diet, compared to routine care, will improve glucose control, among women developing gestational diabetes mellitus during pregnancy.
- Trial name
- iNDIGO (NCT04169243)
- Testing
- New Nordic Diet, Control
- Where
- 3 sites in Sweden
- Volunteers
- 5 people
- Sponsor
- Göteborg University
Sterilization Tubal, Salpingectomy
SALpingectomy for STERilization (SALSTER)
The SALSTER study is a register-based randomized clinical trial (R-RCT) that examines if laparoscopic salpingectomy instead of tubal ligation, as a contraceptive method, has no increased risk for complications and has no negative…
- Conditions
- Sterilization Tubal, Salpingectomy, Laparoscopy, Ovarian Reserve
- Trial name
- SALSTER (NCT03860805)
- Testing
- Laparoscopic tubal ligation, Laparoscopic bilateral salpingectomy
- Where
- Sweden
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Rheumatoid Arthritis
Mussels, Inflammation and Rheumatoid Arthritis (MIRA)
Rheumatoid arthritis (RA) is a chronic disease that affects ~1% of the population. A large proportion of patients with established disease have persistent high disease activity in spite of existing effective pharmacological…
- Trial name
- MIRA (NCT02522052)
- Testing
- Blue mussel diet, Meat/Control diet
- Where
- Sweden
- Volunteers
- 23 people
- Sponsor
- Göteborg University
Dependency
Comprehensive Geriatric Assessment for Frail Older People
The study "Comprehensive Geriatric Assessment for frail older people in Swedish acute care settings - a randomized controlled study" comprised two study arms: one intervention and one control group.
- Trial name
- NCT02773914
- Testing
- Comprehensive Geriatric Assessment
- Where
- Sweden
- Volunteers
- 155 people
- Sponsor
- Göteborg University
Diabetes, Celiac Disease
Gfree - For Improved Blood Sugar and Reduced Inflammation.
The goal of this clinical trial is to reduce inflammation and improve glycemic control in healthy volunteers, parents, as well as children, adolescents and adults with or without diabetes.
- Conditions
- Diabetes, Celiac Disease, Autoimmunity, Metabolic Disease
- Trial name
- NCT05894746
- Testing
- gluten-free, probiotic, gluten
- Where
- 2 sites in Sweden
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Rheumatoid Arthritis
ADIRA (Anti-inflammatory Diet In Rheumatoid Arthritis)
Rheumatoid arthritis (RA) is a chronic inflammatory disease that affects 0.5-1% of the population, and where many patients in spite of modern pharmacological treatment fail to reach remission.
- Trial name
- ADIRA (NCT02941055)
- Testing
- Fiber diet, Protein diet
- Where
- Sweden
- Volunteers
- 56 people
- Sponsor
- Göteborg University
Spinal Cord Injury Cervical, Tendon Transfer
Combined Nerve and Tendon Transfer for the Restoration of Hand Function in Individuals With Tetraplegia
Tetraplegia after a cervical spinal cord injury (C-SCI) radically alters an individual's ability to perform normal activities of daily life due to paralysis in all extremities, resulting in lifelong dependence.[1] Traditional…
- Conditions
- Spinal Cord Injury Cervical, Tendon Transfer, Nerve Transfer, Rehabilitation
- Trial name
- [CNaTT] (NCT04276181)
- Where
- Sweden
- Volunteers
- 94 people
- Sponsor
- Göteborg University
Functional Abdominal Pain Syndrome
Digital Psychological Intervention for Pediatric Functional Abdominal Pain Disorders in Primary Care
The project involves researching two psychological treatments for functional abdominal pain in children. The treatments will be offered to children as an early intervention, at primary care level.
- Trial name
- FAPD (NCT06481072)
- Testing
- Digital patient education, Digital patient education and iCBT
- Where
- Sweden
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Anomia, Aphasia
Effects of Verb Network Strengthening Treatment (VNeST) on Word Finding in Aphasia
Although there is evidence that speech-language therapy may improve speech in language disorders following left hemisphere stroke there is still a lack of evidence for which types of therapy are effective.
- Conditions
- Anomia, Aphasia, Stroke
- Trial name
- NCT05152979
- Testing
- Verb Network Strengthening Treatment (VNeST)
- Where
- Sweden
- Volunteers
- 2 people
- Sponsor
- Göteborg University
Carbohydrate Metabolism, Lipid Metabolism
Nutrient Timing in Connection to Evening Exercise
Physical exercise (PE) significantly influences insulin sensitivity (IS), glucose control and overall metabolic health. While PE effectively enhances IS and glucose regulation, the timing of nutrient intake, before and after…
- Conditions
- Carbohydrate Metabolism, Lipid Metabolism, Blood Glucose, Oral Glucose Tolerance Test
- Trial name
- NCT06400836
- Testing
- Carbohydrate timing - carbohydrate intake before or after exercise
- Where
- Sweden
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Göteborg University