Clinical trials: sponsored by Henry Ford Health System
Tricuspid Regurgitation
Heterotopic Implantation Of the Edwards-Sapien Transcatheter Aortic Valve in the Inferior VEna Cava for the Treatment of Severe Tricuspid Regurgitation (HOVER)
The goal of this study is to determine the short term safety (<30 days) and efficacy (6 months) of the heterotopic implantation of the Edwards-Sapien XT valve in the inferior vena cava for the treatment of severe tricuspid…
- Trial name
- HOVER (NCT02339974)
- Testing
- Heterotopic Implantation Of the Edwards-Sapien XT Transcatheter Valve in the Inferior VEna Cava
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Henry Ford Health System
Carcinoma, Basal Cell
Laser Treatment of Basal Cell Carcinoma Under Imaging Guidance
This pilot study will examine the treatment of basal cell carcinoma (BCC) with laser technology under the guidance of imaging modalities to assist with surgical excision, including optical coherence tomography imaging (OCT) and…
- Trial name
- NCT05138328
- Testing
- Treatment of basal cell carcinoma with Nd:YAG laser under imaging guidance of optical coherence tomography (OCT)
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Henry Ford Health System
Scar, Hypertrophic Scar
The Efficacy and Molecular Mechanism of Botulinum Toxin in the Reduction of Breast Reduction Mammoplasty Scar Formation
1. Test the ability of botulinum toxin type A, when injected into the surgical incision at the time of surgery, to decrease postoperative scar scores compared to control (normal saline) in a double-blinded randomized control…
- Conditions
- Scar, Hypertrophic Scar, Mammary Disorder
- Trial name
- NCT03887377
- Testing
- Botulinum Toxins, Normal saline
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Carcinoma, Non-Small-Cell Lung
Toward High Fidelity Adaptive Radiotherapy in the Thorax
Daily adaptive radiotherapy with individualized planning margins for thoracic and pelvic cancer patients will increase the potential of reducing dose to OARs, thereby reducing treatment-related toxicities and ultimately providing…
- Trial name
- NCT04731571
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Henry Ford Health System
Anterior Cruciate Ligament Tear
Anterior Cruciate Ligament Reconstruction Hybrid Remnant Repair
Patients between 14-60 years of age who will undergo an anterior cruciate ligament (ACL) reconstruction between Nov 1, 2021- Dec 31, 2023, will have their charts reviewed be approached in clinic when the surgery is scheduled…
- Trial name
- NCT05494073
- Testing
- ACL Reconstruction with Hybrid Remnant Repair, ACL Reconstruction without Hybrid Remnant Repair
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Henry Ford Health System
Shift-work Disorder
Use of Consumer Sleep Technology to Treat Shift Work Disorder
The purpose of this study is to examine the effectiveness of a personalized light exposure schedule for Shift Work Disorder (SWD) in night shift workers compared to a non-personalized light exposure schedule.
- Trial name
- SHIFT (NCT05186233)
- Testing
- Phototherapy
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Henry Ford Health System
Blood Flow Restriction
BFR Therapy in Patients With Rotator Cuff Tears
The purpose of this study is to examine the effect of utilizing blood flow restriction (BFR) therapy in patients treated both non operatively and operatively for rotator cuff tears (RCT).
- Trial name
- NCT04384120
- Testing
- Blood Flow Restriction Therapy, Traditional Therapy
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Bariatric Surgery Candidate, Alcohol Drinking
Reducing Alcohol Use Post-Bariatric Surgery
Despite bariatric surgery being the most effective weight loss intervention for patients who are severely obese, as many as 1 in 5 patients will develop an alcohol use disorder after their surgery.
- Trial name
- NCT04788316
- Testing
- CBI and Text messaging
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Henry Ford Health System
Behavior, Health
Parent-Child Memory Study: Improving Future Thinking Among Mothers
Parents of children from impoverished communities are disproportionately more likely to engage in harsh physical discipline, which can lead to serious clinical outcomes, including suicidal ideation and attempts.
- Trial name
- NCT06145919
- Testing
- Episodic Future Thinking (EFT), Episodic Recent Thinking (ERT)
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Breast Cancer Female
Assessment of Breast Cancer Patients Satisfaction and Health Related Quality of Life Outcomes
The purpose of the study is to learn more about the quality of life and satisfaction with breast cancer surgical treatment and education from patient reported outcome data.
- Trial name
- NCT03333122
- Where
- United States
- Volunteers
- 575 people
- Sponsor
- Henry Ford Health System
Behavior, Health
Train Your Brain: A Pilot Project to Improve Memory and Decision Making
The goal of this clinical trial is to pilot a computer-based working memory training program to improve delay discounting (DD) and prevent substance use among at-risk adolescents in a traditionally underserved area.
- Trial name
- NCT05879198
- Testing
- Computer-based Intervention
- Where
- 2 sites in United States
- Volunteers
- 23 people
- Sponsor
- Henry Ford Health System
Head and Neck Cancer, Carcinoma, Squamous Cell
Erlotinib (Tarceva) During First Line Standard Platinum Containing Chemo for Advanced Squamous Cell Head and Neck Cancer
The purpose of this study is to determine if combination Erlotinib, Cisplatin/Carboplatin, and Paclitaxel are effective first line treatment for metastatic, recurrent and persistent squamous cell carcinoma of the head and neck.
- Trial name
- NCT00448240
- Testing
- Erlotinib
- Volunteers
- 6 people
- Sponsor
- Henry Ford Health System
Opioid Use
FOREward Together: Training Peer Recovery Coaches to Promote Retention and Adherence to MOUD
This project aims to implement a peer-led intervention to support retention and adherence to medications for opioid use disorder among low-income adults in Detroit, as well as a training manual for peer recovery coaches serving…
- Trial name
- NCT05098795
- Testing
- Behavioral Activation (BA)
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Henry Ford Health System
Behavioral Health
Improving Future Thinking Among Mothers to Reduce Harsh Parenting and Improve Child Outcomes
Parents of children from impoverished communities are disproportionately more likely to engage in harsh physical discipline, which can lead to serious clinical outcomes, including suicidal ideation and attempts.
- Trial name
- NCT05229146
- Testing
- Episodic Future Thinking
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Behavioral Health
Improving Delay Discounting to Decrease Harsh Parenting Among Parents Receiving Substance Use Treatment
Parents with substance use disorders are disproportionately more likely to engage in harsh physical discipline, which can lead to serious clinical outcomes, including child maltreatment and the intergenerational transmission of…
- Trial name
- NCT05229120
- Testing
- Episodic Future Thinking
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Tennis Elbow, Lateral Epicondylitis
Efficacy Bioinductive Implant for Tennis Elbow (Lateral Epicondylitis)
The investigators are testing the efficacy of a new, FDA-approved bioinductive patch in lateral epicondylitis (tennis elbow) patients.
- Trial name
- NCT03718637
- Testing
- Smith & Nephew Bioinductive Implant, Lateral Epicondylectomy, Ultrasound Imaging
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Henry Ford Health System
Behavior, Health
Peer-Delivered Episodic Future Thinking for Returning Citizens
The goal of this study is to examine the effectiveness of a brief, episodic future thinking (EFT) intervention in a substance use treatment setting serving returning citizens with substance use disorders (SUD).
- Trial name
- NCT06119503
- Testing
- Elongating Time HOrizons for Reentry (ETHoR), Standardized Episodic Thinking (SET)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Post Inflammatory Hyperpigmentation
The Efficacy of Bakuchiol in Treating PIH
Post-inflammatory hyperpigmentation (PIH) is an acquired hyper melanosis that occurs after cutaneous inflammation or injury frequently affecting darker skinned individuals.
- Trial name
- NCT06833996
- Testing
- Bakuchiol, Vehicle
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Obstructive Sleep Apnea of Adult, Pregnancy Related
Mandibular Advancement Device (MAD) in Pregnant Women With Obstructive Sleep Apnea (OSA)
We propose a single-arm trial to test the patient uptake and preliminary efficacy of MAD in a sample of 10 pregnant women with mild-to-moderate OSA.
- Trial name
- OBMAD (NCT06256640)
- Testing
- Mandibular advancement Device
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Head and Neck Neoplasms
HFHS-1801-A Pilot Study of Immunotherapy As Consolidation Therapy for Patients with Recurrent Head and Neck Cancer
The study is a pilot study to explore the feasibility and efficacy of immunotherapy following salvage surgery for recurrent head and neck cancer.
- Trial name
- NCT04188951
- Testing
- Pembrolizumab 25 MG/1 ML Intravenous Solution [KEYTRUDA]
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Henry Ford Health System