Clinical trials: sponsored by Indiana University
Dysphagia, Esophageal
Esophageal Impedance and Manometry Measurements and Dysphagia Symptom Scoring
Comparison of manometry measurements and EndoFlip Balloon measurements in patients with dysphagia and a known esophageal diagnosis
- Trial name
- NCT04503785
- Testing
- Manometry
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Indiana University
Metastatic Cancer, Advanced Cancer
Evaluating Disparities in Precision Oncology
This is a non-randomized observational trial designed to collect detailed clinical, social determinant, and genomic data from patients enrolled in molecular oncology tumor boards across four comprehensive cancer centers.
- Trial name
- EDPO (NCT06081517)
- Testing
- Social Determinants of Health and toxicity questionnaires
- Where
- United States
- Volunteers
- 10,600 people
- Sponsor
- Indiana University
Eosinophilic Esophagitis, Gastroesophageal Reflux Disease (GERD)
Indiana University Gastrointestinal Motility Diagnosis Registry
Develop a registry (list of patients) with accurate clinical motility diagnosis. This registry will help the doctors to identify the patients with specific disease conditions.
- Conditions
- Eosinophilic Esophagitis, Gastroesophageal Reflux Disease (GERD), Gastroparesis, Functional Vomiting
- Trial name
- NCT04506593
- Testing
- no intervention
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Indiana University
Gastroparesis
Magnetic Resonance Imaging of the Brain and Stomach in Healthy Volunteers and Gastroparesis
The study is to lay the groundwork for non invasive imaging of the GI tract and the brain gut interaction
- Trial name
- NCT04282317
- Testing
- MRI scan
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Indiana University
Congestive Heart Failure, Congestive Heart Failure(CHF)
Palliative Care for People With HF
Imagine having heart failure, a condition where the heart struggles to pump blood, making daily life hard. People with heart failure often don't feel well and end up going to the hospital a lot.
- Conditions
- Congestive Heart Failure, Congestive Heart Failure(CHF), Congestive Heart Failure (CHF), Congestive Heart Failure Chronic
- Trial name
- NCT07356843
- Testing
- ADAPT
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Indiana University
Gastroparesis
Indiana University Gastric Electrical Stimulation Registry
The purpose of this study is to develop a clinical registry in patients with Gastric Electrical Stimulation (GES) therapy for gastroparesis to support future gastrointestinal therapies, medical procedures and diagnostics.
- Trial name
- NCT05047289
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Indiana University
Gastroparesis
GI Neuromuscular Pathology Prospective Registry
In this research study, biopsy samples will be collected to provide more insight into the underlying cause of the motility disorders, help direct further investigation into the cause of the underlying condition, provide future…
- Trial name
- NCT02165059
- Testing
- Surgical Full Thickness Biopsy
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Indiana University
Functional Dyspepsia, Small Intestinal Bacterial Overgrowth
Small Intestinal Bacterial Overgrowth: A Prospective Registry
The purpose of this study is to investigate the prevalence of small intestinal bacterial overgrowth (SIBO) in patients who will be undergoing an enteroscopy as an outpatient procedure with symptoms of functional dyspepsia.
- Trial name
- SIBO (NCT01822470)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Indiana University
Anemia, Sickle Cell
Telemedicine for Children With Sickle Cell Disease
The purpose of this study is to learn more about how the use of two different types of telemedicine (distance medical care) can address barriers to receiving comprehensive sickle cell care, and whether care can be improved.
- Trial name
- NCT05087303
- Testing
- Types of Telemedicine Delivery Models
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Indiana University
Germ Cell Cancer Metastatic
Circulating Tumor DNA in Stage I, II, and III Germ-Cell Tumors
This study will evaluate the utility of ctDNA detection in patients with high-risk stage I, stage II, and stage III germ cell tumor disease to develop a tool for post-treatment cancer cell detection.
- Trial name
- NCT07401316
- Testing
- Whole blood for ctDNA
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Indiana University
Secondary Amenorrhea
Effects of Dietary Nitrate in Women With Secondary Amenorrhea
Excessive exercise, disordered attitudes toward eating, physical and psychological stress, and/or hormonal imbalances may result in cessation of menstruation (secondary amenorrhea).
- Trial name
- NCT07019129
- Testing
- Beetroot Juice - Active
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Indiana University
Glaucoma, Ocular Hypertension
Imaging the Effects of Netarsudil (Rhopressa) on the Trabecular Meshwork in Glaucoma and Ocular Hypertension
This study evaluates the effects of netarsudil (Rhopressa) on the trabecular meshwork in subjects with ocular hypertension or open-angle glaucoma.
- Trial name
- NCT07588152
- Testing
- Netarsudil Ophthalmic Solution (Rhopressa), Artificial Tears (AT)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Indiana University
Breast Implant; Complications, Infection or Inflammation
Molecular Mechanisms Associated With Breast Implant Complications
Bacterial biofilms cause implant failures, chronic inflammation, and immune polarization. The study investigates the possible role of bacterial biofilm as a factor in the etiology of Breast Implant Illness.
- Trial name
- MMABIC (NCT05736354)
- Where
- 3 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- Indiana University
Hypertension, Neonatal
Measurement of High Blood Pressure Using Boppli
This study evaluates a new, non-invasive device (Boppli™) that continuously measures blood pressure in newborn infants. The study compares Boppli measurements to standard blood pressure cuff measurements to determine how well the…
- Trial name
- NCT07547917
- Testing
- Boppli
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Indiana University
Presbyopia, Refractive Errors
VisionApp - Refraction and Presbyopia
Recent Android mobile device technology is available which allows user-measured refractive error and reading add power. This technology could be quite useful to the clinical and research community.
- Trial name
- NCT07570602
- Testing
- VisionApp
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Indiana University
Obesity
Estimating the Impact of Obesity Medications on Clinical and Economic Outcomes
The goal of this observational study is to identify the impact of incretin-based obesity medications (e.g., GLP-1 and GLP-1/GIP) on health and economic outcomes among adults who get their health insurance through their employers.
- Trial name
- NCT07640139
- Testing
- Incretin-based therapies (GLP-1 and GLP-1/GIP)
- Where
- United States
- Volunteers
- 125,000 people
- Sponsor
- Indiana University
Chronic Pain, Musculoskeletal Pain
Equipping Patients Using Interventions for Pain and Depression
This project is part of the NIH Helping to End Addiction Long-term (HEAL) initiative (https://heal.nih.gov/). This randomized controlled trial (RCT) is phase 2 of a two-phase, 5-year project with the overarching goal of testing a…
- Conditions
- Chronic Pain, Musculoskeletal Pain, Depression, Health Equity
- Trial name
- EQUIPD (NCT06500780)
- Testing
- Coaching and Decision Aid
- Where
- United States
- Volunteers
- 304 people
- Sponsor
- Indiana University
Wound Healing
Silk Bioprotein as a Wound Dressing for Double-Incision Mastectomy
This study will investigate the utility of Silk bioprotein, an FDA-approved and readily available post-surgical dressing, as a wound dressing for patients undergoing double-incision mastectomy for female-to-male gender…
- Trial name
- NCT06921148
- Testing
- Sylk Wound Dressing, Dermabond/Prineo Dressing
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Indiana University
Music Exposure
Testing the Effects of Music on Short and Long Term Psychological Outcomes and Step Counts in Children
The goal of this clinical trial is to investigate whether asynchronous music can improve outcomes of an 8-week long sport based youth development program.
- Trial name
- NCT07358871
- Testing
- Music in Sport Based Youth Development, No Music Exposure
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Indiana University
HCC, Racial Disparities
Effect of the HCC Liver-Link Intervention
This study is a pilot, multi-center randomized controlled trial testing the HCC Liver-Link intervention, a culturally tailored, multi-level program designed to reduce racial disparities in hepatocellular carcinoma (HCC) care.
- Trial name
- NCT06728293
- Testing
- Liver Link
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Indiana University
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