Clinical trials: sponsored by Istanbul University
Low Risk Prostate Cancer, Clinically Significant Prostate Cancer
Study of PSMA PET/CT Imaging to Help Select Men With Low-Risk Prostate Cancer for Active Surveillance
This is a multicenter, prospective diagnostic accuracy study evaluating the Istanbul PSMA PET/CT Criteria (IPPC) for selecting patients with biopsy-confirmed low-risk prostate cancer (ISUP Grade 1) for active surveillance (AS).
- Trial name
- I-SELECT (NCT07168616)
- Testing
- Ga-68 PSMA11 PET/CT
- Where
- 10 sites in Turkey (Türkiye)
- Volunteers
- 201 people
- Sponsor
- Istanbul University - Cerrahpasa
Juvenile Idiopathic Arthritis
Efficiency of Supervised Exercise Program Versus Mobile-Based Exercise Program in Juvenile Idiopathic Arthritis
Juvenile Idiopathic Arthritis (JIA) is a heterogeneous, idiopathic, chronic inflammatory, rheumatic disease that is most common in childhood and is thought to involve immunological mechanisms in its etiopathogenesis.
- Trial name
- NCT06193681
- Testing
- Pedi@ctivity Exercise Mobile Application Exercise Program, Supervised Exercise Group
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Istanbul University - Cerrahpasa
Catheter Associated Urinary Tract Infection, Indwelling Urinary Catheter
The Effect of Education on Patients' Attitudes and Anxiety Towards CAUTI Prevention
This research will be carried out determine the effect of education given to patients after urological surgery on their attitudes and anxiety levels towards preventing catheter-related urinary tract infections.
- Conditions
- Catheter Associated Urinary Tract Infection, Indwelling Urinary Catheter, Urologic Surgery
- Trial name
- CAUTI (NCT07172750)
- Testing
- Education on Urinary Catheter Care
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Istanbul University - Cerrahpasa
Vertical Jump, Dynamic Balance
Relationship Between Vertical Jump, Balance, Muscle Strength, Flexibility, and Foot Posture in Artistic Gymnasts
Artistic gymnastics is a highly demanding and technically complex sport that requires strength, flexibility, agility, balance, and coordination (Nassib et al., 2020).
- Conditions
- Vertical Jump, Dynamic Balance, Flexibility, Foot Posture Index Score
- Trial name
- NCT07169812
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Academic Acheivement, Attention
The Effects of Breathing Exercises on Exam Anxiety, Attention Deficit, and Academic Achievement in Students Preparing for University Entrance Exams
This study investigates the effects of breathing exercises on exam anxiety, attention, and academic achievement in students preparing for university entrance exams.
- Conditions
- Academic Acheivement, Attention, Exam Anxiety, Breathing Exercises
- Trial name
- NCT07158060
- Testing
- Breathing Exercises
- Volunteers
- 60 people
- Sponsor
- Istanbul University - Cerrahpasa
Hemiplegia
Periscapular Muscle Activation During Open and Closed Kinetic Chain in Stroke
The goal of this observational study is to compare the activity levels of the periscapular (levator scapula, serratus anterior, infraspinatus, upper, middle and lower trapezius) muscles during open and closed kinetic chain…
- Trial name
- NCT05990413
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Data Accuracy, Bleeding Control
Gingival Retraction for Digital Scan Data
The study aims to identify which retraction method offers optimal balance between tissue displacement, scan clarity, and patient comfort, particularly in the esthetic zone, while avoiding the use of CBCT.
- Trial name
- NCT07119281
- Testing
- Group A: Cordless paste with astringent (EXP): Expasyl (Acteon PVT LTD), Group B: Cordless paste without astringent (MF): Magic FoamCord (Coltene Whaledent AG), Group C: Laser troughing (LT): Diode laser (iLase; Biolase Inc.)
- Where
- 3 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Polycystic Ovary Syndrome (PCOS)
Steroid Profiles in PCOS and Effect of OCP Treatment
This prospective observational study investigates the changes in serum steroid intermediates assessed by liquid chromatography-mass spectrometry (LC-MS/MS) in adolescents and young women with polycystic ovary syndrome (PCOS)…
- Trial name
- PCOSLCMS (NCT07161440)
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Istanbul University
Gonarthrosis
Exercise vs. Topical Diclofenac vs. PRP
Osteoarthritis, the most common type of arthritis, is a chronic and degenerative joint disease. It has been reported to affect more than 300 million adults and elderly individuals worldwide.
- Trial name
- NCT05877027
- Testing
- Exercise, Topical Diclofenac, Platelet-Rich-Plasma (PRP)
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Istanbul University - Cerrahpasa
Osteo Arthritis Knee
Effects of Exercise Versus Topical Agents on Knee Osteoarthritis
Osteoarthritis, a chronic and degenerative joint disease, is the most common type of arthritis and affects more than 300 million adults worldwide.
- Trial name
- NCT05827003
- Testing
- Exercise, Exercise&Topical Agent, Topical Agent
- Where
- Turkey (Türkiye)
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Obstetric Brachial Plexus Injury
Duruöz Hand Index in Obstetric Brachial Plexus Palsy
Obstetric brachial plexus palsy (OBPP) arises from perinatal injury to the brachial plexus, resulting in varying degrees of motor and sensory impairment in the upper extremity.
- Trial name
- NCT07151053
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people
- Sponsor
- Istanbul University - Cerrahpasa
Obesity Hypoventilation Syndrome (OHS), Hypoventilation
Effects of Exercise Training on Exercise Capacity and Sleep Quality in Patients With Obesity Hypoventilation Syndrome
Obesity Hypoventilation Syndrome is defined as a combination of obesity (BMI ≥ 30 kg/m2) and daytime hypercapnia in arterial blood gas analysis (PaCO2 > 45 mmHg) without other pathologies that cause hypoventilation.
- Conditions
- Obesity Hypoventilation Syndrome (OHS), Hypoventilation, Obesity, Respiration Disorders
- Trial name
- NCT05398068
- Testing
- Exercises and Diet, Diet
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul University
Breath Exercise, Test Anxiety
The Effects of Breathing Exercises Administered to Associate Degree Students on Test Anxiety and Academic Achievement
This study aims to examine the effects of breathing exercises administered to associate degree students on test anxiety and academic achievement.
- Conditions
- Breath Exercise, Test Anxiety, Higher Education Students, Academic Achievement
- Trial name
- NCT07145021
- Testing
- Breathing Exercise Intervention
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Recession, Gingival, Tissue Grafts
Topical Hyaluronic Acid Adjunctive Effects on Healing After Free Gingival Grafting in Smokers and Non-Smokers
Comparison of the healing of free gingival grafts applied to smokers and non-smokers and evaluation of the effect of hyaluronic acid gel on healing of the donor site.
- Trial name
- NCT07143760
- Testing
- Gengigel
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Istanbul University
Depression in Old Age
Efficacy of Metacognitive Training in Older Adults With Depression
Effective pharmacological and psychological treatments for depression are available. However, treatment modalities are not accessible to all patients diagnosed with depression.
- Trial name
- NCT06042283
- Testing
- Metacognitive Training-Silver
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Istanbul University - Cerrahpasa
Sleep, Stress
Effects of Yoga on Sleep and Stress in the Third Trimester of Pregnancy
Many physiological and psychological changes occur during pregnancy. Sleep and stress are among these changes and can negatively impact the pregnancy process. Yoga can improve sleep quality and stress levels during pregnancy.
- Trial name
- NCT07085026
- Testing
- Yoga Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Obese Patients, Overweight (BMI > 25)
Effects of Low-intensity Blood Flow Restriction Exercise on Aerobic Capacity, Muscle Strength, Muscle Size, Biochemical-hormonal Parameters and Antioxidant Parameters in Overweight and Obese Individuals.
Participants will be selected from sedentary men aged 18-30 and over with a body mass index of 25. First, an informed consent form will be signed by the individuals.
- Trial name
- YT BFR (NCT06912919)
- Testing
- BFR-Aerobic Training, Aerobic Training Without BFR
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Fibromyalgia
Comparison of the Effects of Fibromyalgia Syndrome
Massage therapy, one of the complementary and alternative treatments, is commonly used for fibromyalgia syndrome (FMS). It may help improve pain, anxiety, depression, and sleep disorders through the complex interaction of…
- Trial name
- NCT07082166
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Sleep, Newborn
Effects of Music-Based Interventions on Sleep Patterns and Physiological Responses in Premature Newborns: A Systematic Review and Meta-Analysis
Sleep in the neonatal period is a fundamental biological requirement for regulating growth, neurodevelopment, and the immune system.
- Trial name
- NCT07127419
- Volunteers
- 1,415 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Postmortem Care
The Effect of Simulation-Based Postmortem Care on Nursing Students' Knowledge, Skills, and Self-Efficacy Levels
PURPOSE AND TYPE OF THE RESEARCH This study is designed as a randomized controlled experimental study to investigate the impact of simulation-based learning experiences in the teaching of postmortem care on the knowledge, skills…
- Trial name
- NCT07125456
- Testing
- Postmortem Care Teaching Simulation
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
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