Clinical trials: sponsored by Mahidol University
Adult ICU Patients, Pain, Acute
Incidence of Inadequate Pain Treatment in Ventilated Critically Ill Surgical Patients
In SICU, Siriraj hospital there were no protocols place for the management of pain. All decisions were made according the attending physicians.
- Trial name
- NCT03641911
- Where
- Thailand
- Volunteers
- 118 people
- Sponsor
- Mahidol University
Heart Diseases
Effect of Thiamin Supplementation on Thiamin Status in Children With Heart Disease Receiving Diuretic Drugs
The purpose of this study is to determine effect of thiamin supplementation on thiamin status by measuring thiamin pyrophosphate effect in children with heart disease receiving diuretic drugs.
- Trial name
- NCT03989700
- Testing
- Thiamine Mononitrate
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Mahidol University
Back Pain, Instability Lumbar Spine
Relative Stiffness of Lumbar Spine and Hamstrings Muscle Stretching
The purpose of this study is to investigate the effect of lumbopelvic stabilization on hamstrings muscle stretching in individuals with history of low back pain suspected to have a clinical lumbar instability.
- Conditions
- Back Pain, Instability Lumbar Spine, Muscle Tightness
- Trial name
- NCT03787979
- Testing
- Lumbopelvic stiffening technique, Lumbopelvic relaxing technique
- Where
- Thailand
- Volunteers
- 32 people
- Sponsor
- Mahidol University
Anti-Retroviral Agents, Efavirenz
Switching TDF/FTC/EFV to TDF/FTC/RPV VS Continuing TDF/FTC/EFV in HIV Patients With Complete Virological Suppression
According to the Thai National Guidelines for Treatment of HIV/AIDS 2014, the recommended first line ART regimen was 2 NRTIs backbone, TDF and FTC; plus 1 NNRTI, EFV, with RPV as an alternative one.
- Conditions
- Anti-Retroviral Agents, Efavirenz, HIV-1-infection, Sustained Virologic Response
- Trial name
- STEREOS (NCT03251690)
- Testing
- Tenofovir/Emtricitabine/Rilpivirine, Tenofovir/Emtricitabine/Efavirenz
- Volunteers
- 246 people
- Sponsor
- Mahidol University
Radiation Hazard
Knowledge and Awareness of Radiation Hazard in Health-care Personnel
Knowledge and awareness of radiation hazard in health-care personnel; A Quaternary-care academic center study Aim: To determine knowledge and concerning about radiation hazard in anesthetic personnel and surgeon study decide…
- Trial name
- NCT03475927
- Testing
- Concerning and knowledge about radiation hazard questionnaire
- Where
- Thailand
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Gastric Mass
Robot-Assisted or Laparoscopic Resection for Gastric Subepithelial Tumor With Hand-Sewn Repair, a Case Series
There are a lot of surgical techniques in minimally-invasive surgery to remove gastric subepithelium tumor. Surgical approach depend on location and size of tumor. Usefully used Endostapler to cut stomach include lesion.
- Trial name
- NCT03890354
- Testing
- Hand-Sewn Repair
- Where
- Thailand
- Volunteers
- 27 people
- Sponsor
- Mahidol University
Gastric Cancer
Effect of Lymph Node Ratio in Gastric Cancer to Determine Recurrence Rate After Curative Resection
D2 gastrectomy is standard treatment of early gastric cancer in Japan but in other countries there is still some discord, especially in Europe and North America.
- Trial name
- NCT03778710
- Where
- Thailand
- Volunteers
- 155 people
- Sponsor
- Mahidol University
Post Operative Pain
Effect of Pregabalin on Post Operative Pain in Abdominal Hysterectomy Under Spinal Anesthesia With Intrathecal Morphine
This study aims to compare the effect of pre-operative oral pregabalin on post operative morphine consumption after abdominal hysterectomy with/without salpingo-oophorectomy.
- Trial name
- NCT02285010
- Testing
- Pregabalin
- Where
- Thailand
- Volunteers
- 125 people
- Sponsor
- Mahidol University
Asthma
Mold Sensitization Associated Severe Asthma Exacerbation
Mold sensitization is associated with severe asthma exacerbation.
- Trial name
- NCT03690349
- Testing
- Skin test
- Volunteers
- 102 people
- Sponsor
- Mahidol University
Antiemetic for Highly Emetogenic Chemotherapy
Olanzapine Versus Aprepitant Based Antiemetic Regimen for High Emetic Chemotherapy
Aprepitant and olanzapine have been recommended for emesis prevention from highly emetogenic chemotherapy. We hypothesized that olanzapine may lead to less nausea compared to aprepitant based on previous study.
- Trial name
- NCT03876938
- Testing
- aprepitant, olanzapine 10 mg, olanzapine 5 mg
- Where
- 2 sites in Thailand
- Volunteers
- 147 people
- Sponsor
- Mahidol University
Food Allergy
Efficacy of Local Food Extracts at Different Storage Times
Local lyophylized food extracts are available useful in skin prick test and atopy patch test to confirm food allergy. However, the investigators want to know the duration that the investigators can keep the extracts for the usage…
- Trial name
- NCT02774629
- Testing
- prick and patch test
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Mahidol University
Liver Cancer
Ultrasound Guided Thoracic Paravertebral Block for Hepatic Tumors Ablation
Patients undergo percutaneous radiofrequency ablation of hepatic tumors at Siriraj hospital normally receive only intravenous sedative drugs which sometimes can not provide effective pain control.
- Trial name
- NCT02271646
- Testing
- 0.5% marcaine 20ml
- Where
- Thailand
- Volunteers
- 35 people
- Sponsor
- Mahidol University
Sepsis, Septic Shock
Clinical Outcome Study of High-dose Meropenem in Sepsis and Septic Shock Patients
Sepsis and septic shock patients are considered to have a high risk of complications and death. Appropriate antimicrobial therapy plays an important role in determining outcomes in septic patients.
- Conditions
- Sepsis, Septic Shock, Critical Illness, Carbapenem
- Trial name
- NCT03344627
- Testing
- Meropenem standard dose, Meropenem high dose
- Where
- Thailand
- Volunteers
- 76 people
- Sponsor
- Mahidol University
Corneal Ulcer
Painless Subconjunctival Antibiotic and Antifungal Injection in Corneal Ulcer Patients
The propose of this study is to determine the efficacy of 2% xylocaine in reducing pain due to subconjunctival antibiotic and antifungal injection.
- Trial name
- NCT00789646
- Testing
- Lidocaine/NSS, NSS/Lidocaine
- Volunteers
- 10 people
- Sponsor
- Mahidol University
Renal Failure Chronic Requiring Hemodialysis, Poor Quality Sleep
BIA-Guided Dry Weight Assessment on Sleep Quality in Chronic Hemodialysis Patients
Based on many previous data proving hypervolemia in chronic hemodialysis patients could lead to sleep apnea and poor sleep quality.
- Trial name
- BEDTIME (NCT02825589)
- Testing
- BIA
- Where
- Thailand
- Volunteers
- 19 people
- Sponsor
- Mahidol University
Critical Illness, Respiratory Distress Syndrome, Adult
The Study of Pharmacokinetics and Pharmacodynamics of Cisatracurium
Pathophysiological changes influenced by multiple factors in critically ill patients, has a significant impact on pharmacokinetics (PK) and pharmacodynamics (PD) of cisatracurium.
- Conditions
- Critical Illness, Respiratory Distress Syndrome, Adult, Neuromuscular Blockade, Respiratory Failure
- Trial name
- NCT03337373
- Testing
- cisatracurium
- Where
- Thailand
- Volunteers
- 10 people
- Sponsor
- Mahidol University
Chronic Urticaria
The Validity, Reliability and Interpretability of Thai-version of Chronic Urticaria Quality of Life Questionnaire
In the majority of patients with the chronic urticaria, the etiology is unclear, leading to difficulties in treatment and high rates of recurrence.
- Trial name
- CU-Q2oL (NCT02285023)
- Testing
- CU-Q2oL
- Where
- Thailand
- Volunteers
- 166 people
- Sponsor
- Mahidol University
Spinal Anesthesia, Transurethral Resection of Prostate
Spinal Morphine Provides an Effective Pain Control in Patients Undergoing Transurethral Resection of Prostate Gland
Pain after transurethral resection of prostate is considered mild to moderate severity from detrusor muscle spasm and traction from urinary catheter.
- Conditions
- Spinal Anesthesia, Transurethral Resection of Prostate, Analgesia
- Trial name
- NCT02458742
- Testing
- Morphine
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Parkinson Disease
Modified Exercise Programme in Individuals With Parkinson's Disease
A feasibility study using measures of turning function derived from Inertial Measurement Unit sensory before, and after, a modified exercise programme approach.
- Trial name
- NCT03473834
- Testing
- Modified exercise programme, Medication
- Where
- Thailand
- Volunteers
- 22 people
- Sponsor
- Mahidol University
Central Line Complication
Self-invented Intracavitary ECG Wire VS the Commercial System - Certodyn®
Peripherally Inserted Central Catheter (PICC) is considered a central venous line placement (CVL) which mandates the confirmation of the tip's location.
- Trial name
- iECG (NCT03697291)
- Testing
- PS wire
- Where
- 2 sites in Thailand
- Volunteers
- 36 people
- Sponsor
- Mahidol University