Clinical trials: sponsored by Odense University Hospital
Anorectal Malformation
Long-term Outcome in Patients With Anorectal Malformations
Background Anorectal malformations(ARM) are rare and cover congenital defective development of rectum. ARM include a range of congenital conditions and may in varying degrees involve the anorectum.
- Trial name
- LOPAM (NCT02624232)
- Volunteers
- 60 people
- Sponsor
- Odense University Hospital
Heart Diseases
Effect of Snapshot Freeze on Cardiac CT Image Quality
The aim of this study was to investigate the effect of a new motion correction algorithm on image quality and diagnostic utility in unselected patients undergoing coronary cardiac computed tomography, and to investigate if this…
- Trial name
- NCT02618473
- Testing
- non-seloken
- Where
- Denmark
- Volunteers
- 140 people
- Sponsor
- Odense University Hospital
Ischemic Stroke, Paroxysmal Atrial Fibrillation
Paroxysmal Atrial Fibrillation in Patients With Acute Ischemic Stroke
The purpose of this study is to estimate the clinical relevance of monitoring patients with acute ischemic stroke with 48 hours' inpatient cardiac telemetry in relation to evaluate the presence of brief runs of premature atrial…
- Conditions
- Ischemic Stroke, Paroxysmal Atrial Fibrillation, Premature Atrial Complexes
- Trial name
- NCT02610803
- Where
- Denmark
- Volunteers
- 863 people
- Sponsor
- Odense University Hospital
Hypertension
Tailored Intervention to Improve Medication Adherence in Patients With Hypertension
Patients with hypertension have an increased risk of stroke and myocardial infarction. However, poor adherence to treatment with antihypertensives and lipid-lowering agents occurs frequently within this patient group.
- Trial name
- NCT01742923
- Testing
- Complex tailored intervention, Usual care
- Where
- Denmark
- Volunteers
- 532 people
- Sponsor
- Odense University Hospital
Coronary Occlusion/Thrombosis, Peptic Ulcer Hemorrhage
Systematic Screening for Risk-factors for Ulcer Bleeding Before Anti-thrombotic Treatment
In a prospective randomised study design to investigate, if a systematic risk factor screening for bleeding ulcer in patients, who following percutaneous coronary intervention (PCI) commence a one year combination treatment with…
- Trial name
- NCT01447498
- Testing
- Screening for risk factors for ulcer bleeding
- Where
- Denmark
- Volunteers
- 2,024 people
- Sponsor
- Odense University Hospital
Obesity, Spinal Surgery
Haemodynamic Changes During Anaesthesia in the Prone Position, Evaluated Using Transoesophageal Ultrasound
Transoesophageal ultrasound examination before and after prone position.
- Conditions
- Obesity, Spinal Surgery, Anaesthesia, Changes in Left and Right Ventricle Dimension
- Trial name
- NCT02595788
- Testing
- Change from supine to prone position
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Odense University Hospital
Sensorineural Hearing Loss, Deafness
Cochlear Implant and Vestibular Function.
This study investigate weather one type of cochlear implant (CI) surgery (insertion of the electrode via paracentesis of the round window (RWA)) leads to less vertigo than another type of CI surgery (cochleostomy).
- Conditions
- Sensorineural Hearing Loss, Deafness, Hearing Loss
- Trial name
- NCT02584361
- Testing
- Round window approach, Cochleostomy
- Where
- Denmark
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Rectal Cancer
Preoperative Assessment of Mesorectal Lymph Nodes by Dual Energy CT. PUMK-DECT
Endpoints subproject 1: To develop a reproducible method for the detection of lymph nodes by DECT in operation specimens from rectal resection for cancer.
- Trial name
- NCT02592304
- Testing
- Dual energy computed tomography
- Where
- Denmark
- Volunteers
- 70 people
- Sponsor
- Odense University Hospital
Acute Respiratory Failure, Chest Pain
Ultrasonography in the Emergency Department
Aim To investigate if the proportion of correctly diagnosed patients at 4 hours after arrival to the Emergency Department (ED) increases when patients are diagnosed with standard diagnostics and focused ultrasonography…
- Trial name
- NCT02550184
- Testing
- Focused ultrasonographic examination.
- Volunteers
- 288 people
- Sponsor
- Odense University Hospital
Preeclampsia, Type 1 Diabetes
Urine-plasminogen as a Predictor for Development Of Preeclampsia in Pregnant Women With Type 1 Diabetes Mellitus
A tonic active epithelial Na+ channel (ENaC) in pre-eclampsia (PE) escaped normal hormonal control may offer an attractive explanatory model for the pathophysiology of established PE. The channel is activated by plasmin.
- Trial name
- NCT01821053
- Where
- Denmark
- Volunteers
- 85 people
- Sponsor
- Odense University Hospital
Preeclampsia, Hypertension
Hypertension and Urine Protease Activity in Preeclampsia
Preeclampsia (PE) is a common disorder of pregnancy that complicates 4-7% of all pregnancies. It is a serious condition with acute proteinuria and hypertension and varying degrees of edema after 20 weeks of gestation.
- Conditions
- Preeclampsia, Hypertension, Proteinuria, Pregnancy
- Trial name
- HUPP (NCT01828138)
- Testing
- Sodium
- Where
- Denmark
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Unilateral Primary Osteoarthritis of Hip
Comparing the Clinical Effects of Posterior Approach Versus Lateral Approach in Osteoarthritis Patients With a THA
The aim of this study is to investigate the clinical outcome of the two different, but widely used, surgical approaches (Posterior approach and Lateral approach) of primary total hip arthroplasty in patients diagnosed with…
- Trial name
- COMPALA (NCT01616667)
- Testing
- Total hip arthroplasty
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Bone Development
The Vitamin D and Fetal Bone Length Study (VITFBL)
The Vitamin D and fetal bone length study: Vitamin D and its association to bone length in midterm pregnancy.
- Trial name
- NCT02439229
- Where
- Denmark
- Volunteers
- 2,874 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Abortion, Spontaneous
Vitamin D and Angiogenic Markers in Odense Child Cohort 1
The Vitamin D and Angiogenic Marker Study 1: Vitamin D and angiogenic markers in early pregnancy. Epidemiology and associations to early-pregnancy miscarriage
- Trial name
- VITAM (NCT02434900)
- Where
- Denmark
- Volunteers
- 2,874 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Colon Cancer, Rectum Cancer
The Value of Laparoscopic Ultrasound in Patients Undergoing Laparoscopic Resection for Cancer of the Colon or Rectum
The following project deals with a Danish multicenter trial that evaluates the value of Laparoscopic Ultrasound examination (LUS) in laparoscopic surgery for colon and rectum cancer (CRC).
- Conditions
- Colon Cancer, Rectum Cancer, Liver Metastases
- Trial name
- NCT02079389
- Testing
- Lap+Lus
- Where
- 4 sites in Denmark
- Volunteers
- 280 people
- Sponsor
- Odense University Hospital
Hemorrhoids
Symptom Control 1-year After Circular Stapler Anopexy or Diathermy Excision for Prolapsed Haemorhoids
Background: In an international randomised controlled trial we studied how patient self-reported symptoms improved after either a stapled anopexy operation or a diathermy excision of the haemorrhoids.
- Trial name
- NCT00841620
- Testing
- Haemorrhoidectomy a.m. Milligan, Stapled anopexy
- Where
- Denmark
- Volunteers
- 207 people
- Sponsor
- Odense University Hospital
Acute Appendicitis
Acute Appendicitis: The Influence of C-reactive Protein and Leucocytes on Clinical Decision-making
Aim: To investigate if the results of CRP and leucocytes had any positive or negative influence on the surgeon's decision-making when handling patients with suspected AA.
- Trial name
- NCT02304653
- Testing
- Clinical descision making
- Where
- Denmark
- Volunteers
- 226 people
- Sponsor
- Odense University Hospital
Nausea, Vomiting
Efficacy of Two Antiemetic Regimens in Patients Receiving Radiotherapy and Concomitant Weekly Cisplatin
GAND-emesis is a multinational, randomized, double-blind, placebo-controlled, parallel-group study to investigate the efficacy and tolerability of a neurokinin1 receptor antagonist (fosaprepitant dimeglumine) in combination with…
- Conditions
- Nausea, Vomiting, Genital Neoplasms, Female
- Trial name
- GAND-emesis (NCT01074697)
- Testing
- Fosaprepitant dimeglumine
- Where
- 8 sites in Australia, Denmark and 2 more
- Volunteers
- 246 people
- Sponsor
- Odense University Hospital
Metabolic Clearance Rate
Induction of Drug Metabolism: In Vivo Comparison of Carbamazepine and Oxcarbazepine.
This is a study of the possible effect of two antiepileptic drug on enzymes in the liver that metabolizes a number of drugs. It is a well know fact that carbamazepine induces some of these enzymes and this may reduce the effect…
- Trial name
- NCT00260247
- Testing
- carbamazepine oxcarbazepine
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Breast Cancer Recurrent
Breast Cancer Recurrence - the Accuracy of Dual-time PET/CT
The purpose of this study is to elucidate the value of dual-time-point PET/CT in the recurrence of breast cancer and to determine whether the method is better than the modalities used in the standard work up.
- Trial name
- BREAC-AUT (NCT01552655)
- Testing
- Dual-time PET/CT (low-dose)
- Where
- Denmark
- Volunteers
- 101 people
- Sponsor
- Odense University Hospital