Clinical trials: sponsored by Odense University Hospital
Peritoneal Cancer, Peritoneal Metastases
The PIPAC-OPC7 Study: The Use of PET/CT Scans as a Method of Evaluation in Patients Treated With PIPAC, a Pilot Study.
The pilot study will investigate the use of repeated FDG-PET/CT scans in 16 patients with peritoneal metastasis originating from abdominal cancers treated with Pressurized Intraperitoneal Aerosol Chemotherapy.
- Conditions
- Peritoneal Cancer, Peritoneal Metastases, Peritoneal Carcinomatosis, Abdominal Cancer
- Trial name
- NCT06144853
- Testing
- scan
- Where
- Denmark
- Volunteers
- 34 people
- Sponsor
- Odense University Hospital
Familial Hypercholesterolemia
Familial Hypercholesterolemia Interpretive Comment - Nudging to Detection.
Familial hypercholesterolemia is the most common inherited disease of the lipid metabolism, however it remains underdiagnosed. Only 15 % of 30.000 possible patients have been found in Denmark.
- Trial name
- FIND (NCT05614219)
- Testing
- Biochemistry interpretive comment on elevated LDL-C levels
- Where
- 2 sites in Denmark
- Volunteers
- 2,000 people
- Sponsor
- Odense University Hospital
Metastatic Breast Cancer, Response Monitoring
FDG-PET/CT vs. CT for Monitoring Metastatic Breast Cancer
Several studies have shown improved sensitivity of FDG-PET/CT compared with conventional imaging for diagnosing metastatic breast cancer in retrospective and smaller prospective studies.
- Trial name
- MONITOR-RCT (NCT06877949)
- Testing
- FDG-PET/CT, CE-CT
- Where
- 11 sites in Denmark, Germany and 1 more
- Volunteers
- 420 people
- Sponsor
- Odense University Hospital
Diabetes Mellitus, Type 2, Binge-Eating Disorder
Type 2 Diabetes and Binge Eating Disorder (BED)
The goal of this research project is to improve the treatment of individuals living with both type 2 diabetes (T2D) and Binge Eating Disorder (BED).
- Trial name
- NCT06325670
- Testing
- BED treatment, Waitlist
- Where
- Denmark
- Volunteers
- 34 people
- Sponsor
- Odense University Hospital
Acute Decompensated Heart Failure (ADHF)
Efficacy and Safety of Compression Boots in Patients With Acute Decompensated Heart Failure.
The aim of this clinical trial is to investigate whether pulsatile compression therapy can support heart and kidney function in patients admitted with acute heart failure and fluid accumulation in the legs.
- Trial name
- COMPLEX (NCT07377019)
- Testing
- Pulsatile Compression Boots (PCB)
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Odense University Hospital
To Investigate the Physiological Effect of GLP-1 on the Skeleton, Healthy Volunteer
SHORT-term Effects of GLucagon-like Peptide One on BonE
Bone is a dynamic organ that is remodelled throughout life by a coupled process of resorption and formation of bone tissue, which are highly energy-demanding processes.
- Trial name
- SHORT-GLOBE (NCT06722560)
- Testing
- GLP-1 hormone
- Where
- Denmark
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Femoral Neck Fractures, Internal Fixation; Complications
Evaluation of Fracture Migration After Internal Fixation of Femoral Neck Fractures in Younger Adults: A Clinical RCT Using RSA
The goal of the clinical trial is to compare different surgical methods for internal fixation of femoral neck fractures in younger adults.
- Conditions
- Femoral Neck Fractures, Internal Fixation; Complications, Hip Fractures
- Trial name
- NCT06521671
- Testing
- Dynaloc implant, Cannulated cancellous screws, Sliding hip screw
- Where
- 4 sites in Denmark
- Volunteers
- 75 people
- Sponsor
- Odense University Hospital
ED, Adipose Derived Stem Cells
Can Adipose Derived Regenrative Cells be Used for Treating Erectile Dysfunction After Radical Prostatectomy
The goal of this study was to investigate if adipose derived regenerative cells can be used as a treatment for erectile dysfunction following radical prostatectomy.
- Trial name
- NCT07355530
- Testing
- Adipose-Derived Regenerative Cells
- Where
- Denmark
- Volunteers
- 70 people
- Sponsor
- Odense University Hospital
Crohn's Disease of Terminal Ileum
Extended Mesenteric Resection in Ileocecal Crohn's Disease.
The EXCEED project aims to study the role of the mesentery in disease recurrence in Crohn's disease (CD), as evidence suggests that including the mesentery when doing ileocecal resections can significantly reduce recurrence…
- Trial name
- EXCEED (NCT06324838)
- Testing
- Standard laparoscopic ileocecal resection, Extended laparoscopic ileocecal resection
- Where
- Denmark
- Volunteers
- 204 people
- Sponsor
- Odense University Hospital
Primary Hyperparathyroidism
Upfront Ultrasound for Preoperative Localization in Primary Hyperparathyroidism
Primary hyperparathyroidism is caused by overactive parathyroid glands, leading to elevated calcium levels in the blood. The standard preoperative imaging includes both a radiation-based imaging modality and conventional…
- Trial name
- NCT07068867
- Where
- Denmark
- Volunteers
- 99 people
- Sponsor
- Odense University Hospital
Diabetes Mellitus, Comorbidities and Coexisting Conditions
MDT Conferences for People With Diabetes and Multimorbidity
The goal of this observational study is to test if regular meetings (multidisciplinary team conferences) between several different medical doctors can work well in everyday hospital life.
- Trial name
- NOMAD (NCT05913726)
- Where
- Denmark
- Volunteers
- 55 people
- Sponsor
- Odense University Hospital
Psoriatic Arthritis, Enthesitis
Immune-Competent Cell Manifestations in Psoriatic Arthritis Achilles Tendons
Tendon pathologies (enthesitis) are a characteristic component of psoriatic arthritis (PsA), and are observed in 35% to 50% of PsA patients. The Achilles tendon is one of the most commonly affected sites.
- Trial name
- IMPAACT (NCT03248284)
- Testing
- Tendon biopsy procedure
- Where
- 2 sites in Denmark
- Volunteers
- 30 people
- Sponsor
- Odense University Hospital
Rheumatoid Arthritis, Ankylosing Spondylitis
Safety and Efficacy of Capsule FMT in Treatment-naïve Patients With Newly Diagnosed Chronic Inflammatory Diseases
PURPOSE: The main purpose is to explore clinical efficacy and safety associated with capsule FMT (cFMT) performed in newly diagnosed, untreated patients with rheumatic and gastrointestinal chronic inflammatory diseases (CIDs).
- Conditions
- Rheumatoid Arthritis, Ankylosing Spondylitis, Psoriatic Arthritis, Crohn Disease
- Trial name
- FRONT (NCT04924270)
- Testing
- Faecal microbiota transplantation
- Where
- Denmark
- Volunteers
- 200 people
- Sponsor
- Odense University Hospital
Colorectal Cancer Prevention
Prophylactic Properties of Carrot Juice in Patients With High-Risk Colorectal Polyps
The goal of this prospective randomized double-blinded bi-national study is to test the prophylactic effect of polyacetylenes from carrots on the population of patients who had a resection of high-risk adenomas of the large…
- Trial name
- Px7 (NCT06335420)
- Testing
- Carrot juice from Yellowstone carrots cultivars
- Where
- Denmark
- Volunteers
- 400 people
- Sponsor
- Odense University Hospital
Gastroesophageal Reflux, Infant, Newborn, Diseases
Treatment of Gastroesophageal Reflux Disease in Infants
Gastroesophageal reflux disease in infants is not fully understood. Infants are prescribed medical treatments that may not be effective or that contribute to adverse side effects and lead to concerns and expenses for the parents…
- Trial name
- NCT06255886
- Testing
- Protein pump inhibitor., Mother or infant diet
- Where
- 3 sites in Denmark
- Volunteers
- 96 people
- Sponsor
- Odense University Hospital
Stroke, Ischemic Stroke
Robot-Assisted Training Versus Standard Training in Ischemic Stroke
The aim of this randomised controlled trial (RCT) nested in a prospective cohort, is to investigate the superior effect of late-phase robot-assisted versus standard training on motor function, physical function, fatigue, and…
- Trial name
- NCT06273475
- Testing
- Robot-assisted Training, Standard Training
- Where
- 2 sites in Denmark
- Volunteers
- 40 people
- Sponsor
- Odense University Hospital
Obesity, Life Style, Healthy
LiPO Teen (the Lifestyle in Pregnancy and Offspring Teenagers
The study is a follow-up of a Randomized Controlled Trial (RCT) performed in 2007-10 - the "Lifestyle in Pregnancy" LiP study. The LiP study included 360 pregnant women with BMI ≥30 kg/m2 from Odense University Hospital and…
- Conditions
- Obesity, Life Style, Healthy, Follow-up, Gestational Weight Gain
- Trial name
- NCT05774652
- Testing
- Lifestyle intervention Dietary advise and/or advise on physical activity
- Where
- Denmark
- Volunteers
- 301 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Colorectal Cancer (CRC), Colorectal Cancer and Pre-cancer Polyps
Examination of the Large Intestine With Camera Capsule in Patients With Blood Stream Infection With Gut-associated Bacteria
The goal of this observational study is to diagnose colorectal cancer or precancerous tumors in participants over the age of 18 hospitalized with blood stream infection with anaerobic gut-associated bacteria.
- Conditions
- Colorectal Cancer (CRC), Colorectal Cancer and Pre-cancer Polyps, Blood Stream Infection, Anaerobic Infection
- Trial name
- AB-care (NCT06919068)
- Testing
- Colon capsule endoscopy
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Breast Cancer, Prostate Cancer
A Multi-center Investigation of Family Health.
The current healthcare system is unable to identify burdened and vulnerable families affected by cancer, partly due to a lack of knowledge of how cancer affects family health during treatment and survivorship.
- Conditions
- Breast Cancer, Prostate Cancer, Colorectal Cancer, Hematologic Neoplasms
- Trial name
- NCT06433349
- Testing
- Survey and interviews
- Where
- Denmark
- Volunteers
- 240 people
- Sponsor
- Odense University Hospital
Colorectal Cancer, Adenoma
Care for Colon 2015
The investigatior believe that implementing camera capsule endoscopy as a filter test to colonoscopy will increase screening participation, increase the number of individuals with detected intermediate- high risk adenomas or…
- Trial name
- CFC2015 (NCT04049357)
- Testing
- Camera Capsule Endoscopy/ PillCam
- Where
- Denmark
- Volunteers
- 2,031 people
- Sponsor
- Odense University Hospital