Clinical trials: sponsored by Odense University Hospital
Postoperative Atrial Fibrillation
Statin Therapy With Atorvastatin in Surgical Aortic Valve Replacement
Statins have rapid and significant actions that have potentially important (but not yet proven) implications for postoperative atrial fibrillation and cardiac protection in patients undergoing cardiac surgery.
- Trial name
- STARC (NCT05076019)
- Testing
- Atorvastatin 80mg
- Where
- Denmark
- Volunteers
- 266 people
- Sponsor
- Odense University Hospital
Quality of Life, Multiple Myeloma
Quality of Life the Danish Multiple Myeloma Patients
The aim of the project is to improve quality of life for multiple myeloma patients in the future.
- Trial name
- QoL-MM (NCT02892383)
- Where
- 10 sites in Denmark
- Volunteers
- 681 people
- Sponsor
- Odense University Hospital
Prostate Cancer
PRO-MR-RT Systematic Patient-reported Outcomes to Pelvic Online MRgRT
In 2018 the Unity MR-linac was approved for treating patients with online magnetic resonance (MR)-guided radiotherapy. With the MR-linac it is possible to get real-time MR images with high soft tissue contrast, adapt the…
- Trial name
- NCT05615909
- Testing
- Online MR-guided radiotherapy, CT-guided radiotherapy
- Where
- Denmark
- Volunteers
- 156 people
- Sponsor
- Odense University Hospital
Diabetes Mellitus, Type 1, Diabetes Distress
Use of an Online Intervention for the Treatment of Diabetes Distress in Patients With Type 1-Diabetes
This study will investigate whether an online intervention can be helpful in reducing diabetes distress in people with type 1 diabetes and elevated diabetes distress, compared to individual counselling sessions (online…
- Trial name
- NCT06436456
- Testing
- Online psychological intervention, Individual psychological intervention
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Odense University Hospital
Malignant Pleural Effusion, Pleural Neoplasms
OPC5: Pressurized IntraThoracic Aerosol Chemotherapy (PITAC) in Patients With Malignant Pleural Effusion.
This study will monitor and evaluate patient and personnel safety and toxicity during the implementation and evaluation of Pressurized IntraThoracic Aerosol Chemotherapy (PITAC) directed treatment.
- Conditions
- Malignant Pleural Effusion, Pleural Neoplasms, Quality of Life, Chemotherapy Effect
- Trial name
- NCT06421610
- Testing
- PITAC
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Odense University Hospital
Cardiogenic Shock Acute, Acute Myocardial Infarction
Danish Cardiogenic Shock Trial
Cardiogenic shock a serious complication of a heart attack (myocardial infarction). Despite rapid invasive treatment, circulatory support using positive inotropes and mechanical support with intra-aortic balloon counterpulsation…
- Trial name
- DanShock (NCT01633502)
- Testing
- Conventional circulatory support, Impella CP
- Where
- 13 sites in Denmark, Germany and 1 more
- Volunteers
- 360 people
- Sponsor
- Odense University Hospital
Postoperative Infection
Post-operative Antibiotics; Effects on Risk of Infection After Cochlear Implant Surgery
Currently there is little consensus regarding postoperative antibiotic prophylactic treatment and its effect on the postoperative infection rate after Cochlear implantation.
- Trial name
- NCT06177444
- Testing
- Antibiotic
- Where
- Denmark
- Volunteers
- 920 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Hematologic Malignancy, Treatment Adherence
Improving Quality of Life in Older Patients With Frailty and Hematological Cancer Through Geriatric Assessment
The Improve study is a randomized controlled trial investigating the efficacy of adding comprehensive geriatric assessment and treatment to standard of care compared with standard of care in older, frail patients with…
- Conditions
- Hematologic Malignancy, Treatment Adherence, Treatment Complication, Frailty
- Trial name
- IMPROVE (NCT06373471)
- Testing
- Comprehensive geriatric assessment (CGA) and treatment
- Where
- Denmark
- Volunteers
- 152 people
- Sponsor
- Odense University Hospital
Pregnancy in Diabetic, Type 1 Diabetes
Danish Diabetes Birth Registry 2
Pregnancies in women with pre-existing diabetes are considered "high risk" pregnancies, poses daily clinical challenges and in terms of research - a number of unanswered questions.
- Conditions
- Pregnancy in Diabetic, Type 1 Diabetes, Type 2 Diabetes, Parents
- Trial name
- DDBR2 (NCT05678543)
- Where
- 4 sites in Denmark
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Diverticulitis, Colonic, Colon Inflamed
Fecal Transplantation in Patients Colonic Diverticulitis
The goal of this clinical trial is to investigate the safety and effect of fecal microbiome transplantation (FMT) in patients with a former episode of acute colonic diverticulitis.
- Trial name
- NCT06254625
- Testing
- Fecal Microbiome
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Surgery-Complications
Post-operative Residual Voiding Volume Following Bulking and Vaginal Prolapse Surgery and Impact on In-hospital Stay
Post operative urinary retention is a commonly observed complication following women undergoing urogynecology surgery. The trial includes patients undergoing bulking and vaginal prolapse surgery, who are randomized in two…
- Trial name
- POUR (NCT06051916)
- Testing
- residual urine
- Where
- Denmark
- Volunteers
- 84 people
- Sponsor
- Odense University Hospital
Dexamethasone, Hip Dysplasia
The Effect of Perioperative Dexamethasone Administration on Postoperative Pain in Patients Undergoing Periacetabular Osteotomy.
This is an investigator-initiated, Danish mono-center, randomized, placebo-controlled, parallel group, double-blind, superiority trial of dexamethasone on postoperative pain management on patients undergoing operation for hip…
- Conditions
- Dexamethasone, Hip Dysplasia, Postoperative Pain, Postoperative Nausea and Vomiting
- Trial name
- PAODEX (NCT03874936)
- Testing
- Dexamethasone 24mg Solution for Injection, Saline Solution for Injection
- Where
- Denmark
- Volunteers
- 90 people
- Sponsor
- Odense University Hospital
Atrial Fibrillation, Prevention
Atrial Fibrillation, Prevention and Rehabilitation
Evidence shows that people with atrial fibrillation (AF) can benefit from prevention and rehabilitation interventions related to quality of life, lowered anxiety, etc.
- Conditions
- Atrial Fibrillation, Prevention, Rehabilitation
- Trial name
- NCT06337045
- Testing
- Complex prevention and rehabilitation intervention
- Where
- 2 sites in Denmark
- Volunteers
- 50 people
- Sponsor
- Odense University Hospital
Chronic Low-back Pain
COgNitive FuncTional Therapy+ for Chronic Low Back paIn
This study is a patient-blinded 2-arm randomized controlled trial (RCT) assessing the effectiveness (in the short and long term) as well as total healthcare costs of a CFT+ (a combined physiotherapist/psychologist intervention)…
- Trial name
- CONFeTTI (NCT04399772)
- Testing
- Cognitive Functional Therapy+ pathway, Interdisciplinary pain management pathway
- Where
- Denmark
- Volunteers
- 133 people
- Sponsor
- Odense University Hospital
Gastric Cancer, Chemotherapy, Adjuvant
The Efficacy of PIPAC and Minimally Invasive Radical Resection in High-risk Gastric Cancer Patients.
The goal of this randomized clinical trial is to investigate whether pressurized intraperitoneal chemotherapy (PIPAC), delivered immediately after minimally invasive D2 gastrectomy and repeated 6-8 weeks later, improves 12-month…
- Conditions
- Gastric Cancer, Chemotherapy, Adjuvant, Peritoneal Metastases, Minimally Invasive Surgical Procedures
- Trial name
- EPICURE (NCT06295094)
- Testing
- Cisplatin, Doxorubicin
- Where
- 5 sites in United States, Denmark and 3 more
- Volunteers
- 264 people
- Sponsor
- Odense University Hospital
Breast Cancer Lymphedema, Secondary Lymphedema
Lymphaticovenous Anastomosis as Treatment for Lymphedema
The primary aim of this study is to investigate and test whether the use of combined indocyanine green (ICG) lymphography and ultra high frequency ultrasonography can correctly identify lymphatic vessels and venoles in close…
- Conditions
- Breast Cancer Lymphedema, Secondary Lymphedema, Iatrogenic Lymphedema, Lymphedema
- Trial name
- NCT05441943
- Testing
- Lymphovenous anastomosis
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- Odense University Hospital
Malignant Melanoma
Shared Decision Making in Melanoma Patients Receiving Adjuvant Therapy
This study aims to develop test and evaluate a Patient Decision Aid called "The Decision Helper" among melanoma patients eligible for adjuvant treatment.
- Trial name
- NCT06294379
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- Odense University Hospital
Bladder Cancer
The iBlad App - a National, Exploratory Study on a Multimodality Smartphone App for Bladder Cancer Patients
The aims of this project are: to develop and implement a national multimodality application for patients with bladder cancer that builds upon knowledge from the iBLAD study.
- Trial name
- iBLAD-app (NCT05710159)
- Testing
- iBLAD Application to monitor symptoms and quality of life by the use of pateint-reported outcomes
- Where
- 2 sites in Denmark
- Volunteers
- 100 people
- Sponsor
- Odense University Hospital
Anorexia Nervosa, Stress
Cortisol, Hippocampus, and Insula in Anorexia Nervosa.
EXCENTRICC is a platform for scientific collaboration between different disciplines, all working on a common theme: adrenocortical hormones.
- Trial name
- EXCENTRICCAN (NCT05931549)
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Anorexia Nervosa
Whole Gut Microbiome Sequencing in Patients With Anorexia Nervosa
Background. Anorexia nervosa (AN) still carries the highest fatality rate of any psychiatric disease, and less than half of the patients recover, completely refractory to any treatment.
- Trial name
- NCT02217384
- Where
- 3 sites in Denmark
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital