Clinical trials: sponsored by Oregon Health and Science University
HIV/AIDS
Oregon PrEP at Home Study
This demonstration study will evaluate the real-world implementation of long-acting cabotegravir (CAB-LA) for HIV pre-exposure prevention (PrEP) through a partnership between the OHSU Tele-PrEP Program (TPP) and the OHSU Home…
- Trial name
- OR-PrEP@Home (NCT05949203)
- Testing
- Cabotegravir Injection
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Obstetric Labor Complications
Amniotic Fluid Analysis
This is a prospective study that will aid in ensuring the feasibility of timely and correct aspiration of amniotic fluid by study research team that include the clinical team taking care of the patient during her labor, timely…
- Trial name
- NCT06131684
- Testing
- Intrauterine pressure catheter (IUPC) present, Intrauterine pressure catheter (IUPC) absent
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Cirrhosis, Liver, Sarcopenia
Body Composition Changes After TIPS and Associated Clinical Outcomes
The purpose of this study is to prospectively assess the impact of TIPS creation on muscle mass and physical function in patients with cirrhosis, and to determine whether these changes correlate with improved outcomes in patients…
- Trial name
- NCT05420753
- Testing
- Transjugular Intrahepatic Portosystemic Shunt (TIPS) creation
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Oregon Health and Science University
Covid19, Cardiovascular Risk Factor
Cardiovascular Risk Stratification in Covid-19
This retrospective double-cohort study seeks to: 1. Describe the cardiovascular manifestations and electrophysiological (EP) substrate in COVID-19 infection and their association with clinical outcomes; and 2.
- Trial name
- CaVaR-Co19 (NCT04555187)
- Where
- United States
- Volunteers
- 1,355 people
- Sponsor
- Oregon Health and Science University
Portal Hypertension
Feasibility And Safety Of Transjugular Intrahepatic Portosystemic Shunt (TIPS) Creation Using A Radiofrequency Guidewire
A novel radiofrequency (RF) wire created by Baylis Medical (Montreal, CAN) is an FDA cleared device commonly used for percutaneous recanalization procedures.
- Trial name
- NCT03451149
- Testing
- Radiofrequency wire (Powerwire)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Oregon Health and Science University
Obesity, Diabetes
The Effects of Work Schedule and Sleep Patterns on Caregivers' Health
BACKGROUND. Sleep deficiency (not getting enough sleep) is widespread in American adults and can lead to many harmful health outcomes such as a higher risk of obesity, heart disease, and diabetes.
- Conditions
- Obesity, Diabetes, Cancer, Metabolic Syndrome
- Trial name
- NCT01443156
- Where
- United States
- Volunteers
- 211 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Early Math Learning
Promoting Math in Young Children: Leveraging Pediatric Clinics to Reach Underrepresented Children in Rural Communities
The goals of this clinical trial to examine how pediatricians prescribing early math enriching texts to the parents of their patients affects the early math skills of under-resourced pre-kindergarten-aged children in rural…
- Trial name
- MATH (NCT05884541)
- Testing
- TipsbyText Messages
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Surgery, Otolaryngologic Disorder
Digital Intervention Postoperative Protocol
Postoperative recovery after head and neck surgery is complex, and often requires utilization of narcotic medications. The aim of this study is to evaluate reduction in pain and use of opioid medications through Virtual Reality…
- Conditions
- Surgery, Otolaryngologic Disorder, Pain, Postoperative
- Trial name
- NCT04828109
- Testing
- Virtual Reality, Fitbit
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Surgery, Pain, Postoperative
Utilization of Different Virtual Reality Experiences
This trial studies differences between a mindfulness and a gaming virtual reality (VR) experience as a means for preoperative anxiety management and postoperative pain management among patients after head and neck surgery.
- Conditions
- Surgery, Pain, Postoperative, Anxiety, Otolaryngological Disease
- Trial name
- NCT04828980
- Testing
- Oculus Quest: TRIPP, Oculus Quest: Angry Birds
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Carpal Tunnel Syndrome
Local Effects of Acupuncture and Nerve Conduction Studies
Thus study aims to characterize the local, nerve-specific effects of acupuncture on the median and ulnar nerves in the forearm, using nerve conduction studies and quantitative sensory testing.
- Trial name
- NCT03036657
- Testing
- MAC acupuncture needles, Electrostimulator 6c.Pro, Pantheon Research, Venice, CA
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Oregon Health and Science University
Maternal Psychological Distress, Prenatal Stress
Roo Study on Mom and Baby Well-Being
This study employs a randomized controlled trial of an established intervention, Mindfulness Based Cognitive Therapy (MBCT) adapted for pregnancy, to examine effects on various aspects of maternal psychological stress during…
- Conditions
- Maternal Psychological Distress, Prenatal Stress, Infant Development, Functional Neuroimaging
- Trial name
- NCT03809598
- Testing
- Mindfulness Based Cognitive Therapy
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Loneliness, Social Isolation
Virtual Yoga for Social Isolation and Loneliness in Rural Veterans
The overarching goal of this project is to decrease social isolation and loneliness through increased awareness and uptake of virtual yoga group classes among rural Veterans.
- Trial name
- NCT05431166
- Testing
- Virtual Yoga at First 8 weeks, Virtual Yoga at Second 8 weeks
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Oregon Health and Science University
Psychiatric Disorders, Pain
Clinical Utility of Pharmacogenomics of Psychotropic Medications
While the scientific understanding of pharmacogenomics is quickly accelerating, its translation to clinical decision-making (especially in psychiatric practice) has progressed more slowly.
- Trial name
- NCT03907124
- Testing
- Genetically-guided treatment with FDA-approved psychotropic drugs, Treatment as usual (TAU)
- Where
- United States
- Sponsor
- Oregon Health and Science University
Ankylosing Spondylitis, Axial Spondyloarthritis
Terbinafine Treatment of Axial Spondyloarthropathy
This is a pilot study to determine if further research is warranted to assess if anti-fungal therapy is an effective adjunctive treatment for axial spondyloarthropathy
- Conditions
- Ankylosing Spondylitis, Axial Spondyloarthritis, Psoriatic Spondylitis, Spondylitis Secondary to Inflammatory Bowel Disease
- Trial name
- FUN (NCT05119712)
- Testing
- Terbinafine Tablets, Laboratory Testing
- Where
- United States
- Sponsor
- Oregon Health and Science University
Obstructive Sleep Apnea
Use of Sleep Endoscopy to Predict Outcomes of Pediatric Adenotonsillectomy
Pediatric obstructive sleep apnea (OSA) is associated with heavy snoring and brief pauses in breathing during sleep. It affects at least 1-3% of the general pediatric population with greater prevalence among certain high risk…
- Trial name
- NCT02693977
- Testing
- Sleep Endoscopy
- Where
- United States
- Volunteers
- 347 people
- Sponsor
- Oregon Health and Science University
Advanced Care Planning, Dementia
Pilot Study of an Advance Care Planning Intervention Among Persons With Dementia
Advance care planning allows people to have their wishes taken into account even in the advanced stages of the persons' condition and at the end of life when the person may be unable to communicate.
- Trial name
- NCT05049291
- Testing
- telehealth advance care planning
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Oregon Health and Science University
Type 1 Diabetes
Context Aware Data Gathering Study
Automated Insulin Delivery (AID) systems have now become an important standard-of-care for people with T1D and have demonstrated a reduction, but not elimination, of hypoglycemia during long-term studies.
- Trial name
- NCT04154904
- Testing
- Exercise
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Oregon Health and Science University
Obesity, Childhood
Bringing Weight Management Into the Primary Care Pediatric Practice
This project aims to move what is currently a specialty-care model for the management of obesity of children and adolescents into the primary care setting.
- Trial name
- NCT05950620
- Testing
- Medical obesity management.
- Where
- 2 sites in United States
- Volunteers
- 400 people
- Sponsor
- Oregon Health and Science University
Contraception
Cannabidiol and Oral Contraceptive Pills: Exploring a Drug-Drug Interaction
The purpose of this study is to assess how Cannabidiol (CBD) impacts the effectiveness of oral contraceptive (birth control) pills and if CBD changes the possible side effects of birth control pills when CBD and birth control…
- Trial name
- NCT04396730
- Testing
- Cannabidiol Oil, Combined oral contraceptive pill
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Malignancy, Fertility
Ovarian Tissue Freezing For Fertility Preservation
The purpose of this study is to offer an alternative method to women who wish to preserve the possibility of fertility, as well as to learn more about the ability of human eggs to survive and function after long term storage in…
- Trial name
- NCT00902720
- Testing
- Tissue sample storage
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University