Clinical trials: completed, sponsored by Samsung Medical Center
Chronic Obstructive Pulmonary Disease
Pulmonary Rehabilitation Program in COPD Patient
This study was designed in order to evaluate the compliance of a pulmonary rehabilitation program using a wearable device and the application effect of the program according to the characteristics of each patient, in COPD…
- Trial name
- NCT05906264
- Testing
- Tele-intervention
- Where
- South Korea
- Volunteers
- 64 people
- Sponsor
- Samsung Medical Center
Abdominal Aortic Aneurysms (AAA), Endovascular Aneurysm Repair (EVAR)
Efficacy and Safety of Antiplatelet Therapy After Endovascular Aortic Repair
This study was a target trial emulation using the National Health Claims database established by the Korean National Health Insurance Service (K-NHIS). 8,325 patients were included.
- Trial name
- EVAR_DAPT_SAPT (NCT06876727)
- Volunteers
- 8,325 people
- Sponsor
- Samsung Medical Center
Acute Coronary Syndrome, Ischemic Heart Disease
PreDiction and Validation of Clinical CoursE of Coronary Artery DiSease With CT-Derived Non-Invasive HemodYnamic Phenotyping and Plaque Characterization (DESTINY Study)
Acute coronary syndrome (ACS) and sudden cardiac death can be the first manifestation of coronary artery disease and are the leading cause of death in the majority of the world's population.
- Trial name
- DESTINY (NCT04794868)
- Testing
- CCTA-derived high risk plaque characteristics, CFD-derived hemodynamic parameters
- Where
- 2 sites in China, South Korea
- Volunteers
- 356 people
- Sponsor
- Samsung Medical Center
ST-segment Elevation Myocardial Infarction (STEMI)
Angio-IMR and Cardiac MR-derived MVO in STEMI Patients
Coronary microcirculatory dysfunction has been known to be prevalent even after successful revascularization of ST-segment elevation myocardial infarction (STEMI) patients.
- Trial name
- NCT04828681
- Testing
- Cardiac magnetic resonance imaging
- Where
- 2 sites in United States, China
- Volunteers
- 324 people
- Sponsor
- Samsung Medical Center
Coronary Artery Disease, Coronary Artery Stenosis
Nationwide Cohort Study of Antiplatelet Agents as Primary Prevention
There is no specific recommendation regarding pharmacologic treatment as primary prevention for patients with intermediate coronary artery stenosis whose revascularization was deferred based on negative fractional flow reserve…
- Trial name
- NHIS (NCT06281041)
- Testing
- Antiplatelet Agents
- Where
- South Korea
- Volunteers
- 4,657 people
- Sponsor
- Samsung Medical Center
Ischemic Heart Disease, Microvascular Coronary Artery Disease
Prognostic Impact of Cardiac Diastolic Function and Coronary Microvascular Function
The DIAST-CMD registry (Prognostic Impact of Cardiac Diastolic Function and Coronary Microvascular Function) is prospective registry which enrolled patients who underwent echocardiography, cnically-indicated invasive coronary…
- Conditions
- Ischemic Heart Disease, Microvascular Coronary Artery Disease, Diastolic Dysfunction, Heart Failure With Preserved Ejection Fraction
- Trial name
- DIAST-CMD (NCT05058833)
- Testing
- Echocardiography, Coronary flow reserve and index of microcirculatory dysfunction
- Where
- 4 sites in United States, South Korea
- Volunteers
- 800 people
- Sponsor
- Samsung Medical Center
Congenital Heart Disease
Impact of a Cardiac and Mental Health Rehab Program on Well-Being and Fitness in Young Adults With Fontan Circulation: A Randomized Trial
Helping Young Adults With Fontan Circulation Feel Better and Stay Active What is the study about? This study looked at how a special program could help young adults with Fontan circulation feel better mentally and physically.
- Trial name
- (NCTXXXXXXXX) (NCT06844149)
- Testing
- CPR; (Cardiac and Psychosocial Rehabilitation) with Cardiac Rehabilitation, CR; Home-Based Cardiac Rehabilitation, Usual Care
- Where
- South Korea
- Volunteers
- 36 people
- Sponsor
- Samsung Medical Center
Chronic Stroke, Subacute Stroke
Effect of Lower Limb Constraint Induced Movement Therapy Using a Torque-Assisted Exoskeletal Wearable Device
The aim of this study was to investigate the effects of lower limb constraint induced motor therapy using the robotic rehabilitation device on ambulatory function in chronic stroke patients.
- Trial name
- CIMT (NCT06830707)
- Testing
- experimental group
- Where
- South Korea
- Volunteers
- 16 people
- Sponsor
- Samsung Medical Center
Pediatric Cancer, Psychology, Child
Usability and Utility of Mindfulness-based Life Management Social Robots for Children and Adolescents in the Long-term Treatment
The purpose of this study is to apply social robot-based mindfulness-based life management content to pediatric and adolescent patients in the long-term disease treatment process and to assess usability and effectiveness of the…
- Trial name
- NCT06763042
- Testing
- Mindfulness-based Life Management Social Robots
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Samsung Medical Center
Telemedicine, Ultrasonography
Tele-education in Ultrasound Training
The study aims to assess the impact of remote guidance in ultrasound training for medical professionals new to abdominal ultrasound.
- Conditions
- Telemedicine, Ultrasonography, Education, Medical, Continuing
- Trial name
- NCT06171828
- Testing
- Head-Mounted Display (HMD) to communicate with a supervisor remotely
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Early Mobility, Critically Ill
Early Mobilization in Ventilated SEpsis & Acute Respiratory Failure Study
Early mobilization in Ventilated sEpsis \& acute Respiratory failure Study: EVER Study
- Trial name
- EVER (NCT04582760)
- Testing
- early mobilization
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Samsung Medical Center
Cervix Cancer, Radiotherapy, Adjuvant
Postoperative Hypofractionated Intensity-modulated Radiation Therapy with Concurrent Chemotherapy in Cervical Cancer
To investigate the acute toxicities, late toxicities, and treatment results when the early cervical cancer patients are treated by concurrent chemotherapy with hypofractionated intensity-modulated radiotherapy (2.5 Gy X 16…
- Conditions
- Cervix Cancer, Radiotherapy, Adjuvant, Radiotherapy, Intensity-Modulated, Hypofractionated Dose
- Trial name
- NCT03239613
- Testing
- POHIM-CCRT
- Where
- South Korea
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Nursing, Education
Utilizing of Augmented Reality Technology Education Program for Nurse
It is important to provide practice-oriented education for nurses in a safe environment. As it became difficult to maintain face-to-face education and practice environment due to COVID-19, a new paradigm for nurse education was…
- Trial name
- NCT05629663
- Testing
- AR guidance with Hololens 2
- Where
- South Korea
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Metastatic Non-Small Cell Lung Carcinoma
Pembrolizumab for Metastatic NSCLC Patients Expressing PD-L1 Who Have Their Own PDX
This is a single center, open-label, single arm study in patients with metastatic non-small cell lung cancer (NSCLC) expressing PD-L1 after failure of platinum-based combination chemotherapy.
- Trial name
- NCT03134456
- Testing
- Pembrolizumab Injection
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Samsung Medical Center
Neoplasm
The Samsung Medical Center Comprehensive Cancer Center Registry from 2008 to 2023
This is a retrospective cohort study using the Samsung Medical Center Cancer Registry, including cancer patients between 2008 and 2022. To monitor trends in patient demographics, treatment patterns, and outcomes.
- Trial name
- SCCCR08-23 (NCT06703957)
- Where
- South Korea
- Volunteers
- 301,055 people
- Sponsor
- Samsung Medical Center
Diabetes Mellitus, Type 1
Individualized Automatic Target Coaching Message for Glycemic Management and Depressive Symptom
This is a single-center, randomized, prospective, feasibility and acceptability trial in patients with type 1 diabetes. For six weeks, the intervention group will receive weekly personalized coaching messages for glycemic…
- Trial name
- NCT06525454
- Testing
- Personalized coaching messages for blood glucose and emotions
- Where
- South Korea
- Volunteers
- 18 people
- Sponsor
- Samsung Medical Center
Neoplasm, Breast
Cooling Cap Trial to Prevent Permanent Chemotherapy-induced Alopecia in Breast Cancer Patients
This study aims to examine whether the PSCS2 is effective in reducing chemotherapy-induced alopecia in women with breast cancer undergoing neoadjuvant or adjuvant chemotherapy.
- Trial name
- NCT04678544
- Testing
- Scalp cooling system 2
- Where
- South Korea
- Volunteers
- 170 people
- Sponsor
- Samsung Medical Center
Interstitial Cystitis
Genetic and Histopathologic Characteristics of Interstitial Cystitis
Genetic and Histopathologic Characteristics of Interstitial Cystitis
- Trial name
- NCT03523559
- Testing
- bladder tissue of Interstitial Cystitis and normal bladder tissue
- Where
- South Korea
- Volunteers
- 14 people
- Sponsor
- Samsung Medical Center
Stroke, Repetitive Transcranial Magnetic Stimulation
Effect of Cerebral and Cerebellar rTMS in Stroke Patient
This study is based on the characteristics of motor learning theory and motor learning neural network to improve motor function in stroke patients.
- Conditions
- Stroke, Repetitive Transcranial Magnetic Stimulation, rTMS, Motor Recovery
- Trial name
- NCT04570774
- Testing
- Repetitive transcranial magnetic stimulation
- Where
- South Korea
- Volunteers
- 56 people
- Sponsor
- Samsung Medical Center
Epilepsy
A Study on Telemedicine Applied to Actual Outpatient Clinic for Epilepsy
This is an observational study to confirm the non-inferior effectiveness on health outcomes of tele-counseling or tele-prescription, which was the first outpatient system applied to the actual medical sites in Korea during the…
- Trial name
- NCT05418257
- Testing
- (exposure) telemedicine
- Where
- South Korea
- Volunteers
- 307 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center