Clinical trials: sponsored by Seoul National University Hospital
Ischemic Reperfusion Injury, Other Reconstructive Surgery
RIPC During Free Flap With Preoperative Radiotherapy
Remote ischemic preconditioning (RIPC) has shown organ-protective effects in many clinical settings including patients with ischemic heart disease.
- Conditions
- Ischemic Reperfusion Injury, Other Reconstructive Surgery, Radiotherapy
- Trial name
- NCT03535623
- Testing
- remote ischemic preconditioning (RIPC)
- Where
- South Korea
- Volunteers
- 44 people
- Sponsor
- Seoul National University Hospital
Marginal Zone B-cell Lymphoma
Bendamustine Plus Rituximab (BR) for Relapsed or Progressive Marginal Zone B-cell Lymphoma (MZBCL)
This study will be conducted to evaluate the efficacy of Bendamustine Plus Rituximab (BR) in patients with relapsed or progressive Marginal Zone B-cell Lymphoma (MZBCL).
- Trial name
- NCT02433795
- Testing
- bendamustine plus rituximab
- Where
- 11 sites in South Korea
- Volunteers
- 27 people
- Sponsor
- Seoul National University Hospital
Premature Birth of Newborn, Intervention Studies
Direct Swallowing Training and Oral Sensorimotor Stimulation in Preterm Infants
This is randomized controlled trial investigating the effects of direct swallowing training and oral sensorimotor stimulation in preterm infants on oral feeding performance.
- Trial name
- NCT02508571
- Testing
- Direct swallowing training (DST), Oral sensorimotor stimulation (OSMS)
- Where
- South Korea
- Volunteers
- 189 people
- Sponsor
- Seoul National University Hospital
Arthrodesis
Comparison of Ultrasonic Osteotome and Conventional Drill Osteotome
Ultrasonic bone osteotome has been utilized in various surgical field, but the use in neurosurgery especially in spine surgery is not widely spread.
- Trial name
- SONO (NCT02487901)
- Testing
- ultrasonic osteotome, drill
- Where
- South Korea
- Volunteers
- 190 people
- Sponsor
- Seoul National University Hospital
Anastomosis
Comparison Between End-to-side and Side-to-side Anastomosis After Laparoscopic Right Hemicolectomy
The purpose of this study is to evaluate the efficacy of end-to-side anastomosis after laparoscopic right hemicolectomy compared with that of side-to-side anastomosis.
- Trial name
- NCT02897531
- Testing
- ES anastomosis, SS anastomosis
- Where
- 2 sites in South Korea
- Volunteers
- 130 people
- Sponsor
- Seoul National University Hospital
Locally Advanced or Metastatic NSCLC
Osimertinib for NSCLC With EGFR Exon 20 Insertion Mutation
This is a single-arm, non-randomized multicentre phase 2 study in NSCLC patients with EGFR exon 20 insertion mutation, whose disease has progressed on standard chemotherapy.
- Trial name
- NCT03414814
- Testing
- Osimertinib 80 MG [Tagrisso]
- Where
- South Korea
- Volunteers
- 15 people
- Sponsor
- Seoul National University Hospital
Tuberculosis, Multidrug-Resistant
Treatment Shortening of MDR-TB Using Existing and New Drugs
The purpose of this study is to compare the efficacy of a 'new treatment regimen including delamanid, linezolid, levofloxacin, and pyrazinamide for nine or twelve months (investigational arm)' and 'the standard treatment regimen…
- Trial name
- MDR-END (NCT02619994)
- Testing
- Linezolid, Delamanid, Levofloxacin
- Where
- South Korea
- Volunteers
- 214 people
- Sponsor
- Seoul National University Hospital
Aplastic Anemia, Myelodysplastic Syndromes
Posaconazole Prophylaxis During ATG Treatment for hMDS/AA Patients
To investigate the efficacy of posaconazole as prophylaxis antifungal agent in aplastic anemia / hypoplastic myelodysplastic syndrome (AA/hMDS) patients undergoing antithymocyte globulin (ATG) treatment
- Conditions
- Aplastic Anemia, Myelodysplastic Syndromes, Fungal Infection
- Trial name
- NCT03318159
- Testing
- Posaconazole
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Seoul National University Hospital
Relapsed or Refractory EBV-and CD30-positive Lymphomas
Brentuximab Vedotin in Patients With Relapsed or Refractory EBV-and CD30-positive Lymphomas
This is an open-label, non-randomized, multi-center, phase II trial of brentuximab vedotin to evaluate ORR primarily in patients with EBV- and CD30-positive lymphomas.
- Trial name
- Bretuximab (NCT02388490)
- Testing
- brentuximab vedotin
- Where
- 3 sites in South Korea
- Volunteers
- 25 people
- Sponsor
- Seoul National University Hospital
Postoperative Inflammation, Postoperative Fever
Comparison of Perioperative Outcomes Between Energy Device During Laparoscopic Gastrectomy
To find out which instrument can be much better for laparoscopic gastrectomy among Harmonic scalpel, Ligasure Maryland, Thunderbeat comparing postoperative CRP level in each group
- Trial name
- NCT03356626
- Testing
- ULTRACISION Harmonic Scalpel, Ligasure Maryland, Thunderbeat
- Where
- South Korea
- Volunteers
- 189 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Myelopathy Cervical, Kyphosis Post Surgical
Comparison Between C3-6 Laminoplasty and C3 Laminectomy With Cervical Laminoplasty
Investigators performed a prospective randomized controlled trial for comparing postoperative clinical and radiological outcomes between C3 laminectomy with laminoplasty and C3-6 laminoplasty.
- Conditions
- Myelopathy Cervical, Kyphosis Post Surgical, Neck Pain, Ossification of Posterior Longitudinal Ligament
- Trial name
- NCT05006495
- Testing
- C3 laminectomy, C3 laminoplasty
- Where
- South Korea
- Volunteers
- 126 people
- Sponsor
- Seoul National University Hospital
Aortic Valve Disease
Comparison of Two Pericardial Bioprostheses in AVR
The purpose of the study is to compare early and 1-year hemodynamic performance and clinical outcomes after aortic valve replacement using two pericardial bioprosthesis, Avalus and Carpentier Edwards Perimount Magna Ease.
- Trial name
- NCT03796442
- Testing
- AVR with AVALUS, AVR with CEPME
- Where
- 2 sites in South Korea
- Volunteers
- 140 people
- Sponsor
- Seoul National University Hospital
Anesthesia, General, Neuromuscular Blockade
Pharmacokinetic-pharmacodynamic Analysis of Sugammadex in Children
This study administers sugammadex sodium to pediatric patients under general anesthesia with rocuronium. Pharmacokinetic and pharmacodynamic analysis are performed based on plasma concentration of sugammadex sodium and monitoring…
- Trial name
- NCT03943888
- Testing
- Sugammadex Injection 2mg/kg, Sugammadex Injection 4mg/kg, Sugammadex Injection 8mg/kg
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Seoul National University Hospital
Lateral Epicondylitis
Treatment of Tendon Injury Using Mesenchymal Stem Cells
Main purpose of this study is to evaluate efficacy and safety of allogenic adipose-derived mesenchymal stem cells(ALLO-ASC) in treatment of tendon injury.
- Trial name
- ALLO-ASC (NCT01856140)
- Testing
- ALLO-ASC(allogeneic adipose derived mesenchymal stem cell) injection
- Where
- South Korea
- Volunteers
- 12 people
- Sponsor
- Seoul National University Hospital
Acute Leukemia
Micafungin Prophylaxis During 1st Induction Chemotherapy for De Novo Acute Leukemia
The purpose of this study is to determine whether prophylaxis with micafungin is effective in the induction chemotherapy for newly diagnosed acute leukemia patients.
- Trial name
- NCT02440178
- Testing
- Micafungin
- Volunteers
- 66 people
- Sponsor
- Seoul National University Hospital
Orthostatic; Hypotension, Neurogenic
Treatment and Prognosis of Neurogenic Orthostatic Hypotension : A Prospective Randomized Study
Compare the effect of treatment of midodrine and pyridostigmine in neurogenic orthostatic hypotension and investigate the quality of life of treatment of neurogenic orthostatic hypotension.
- Trial name
- NCT02308124
- Testing
- Midodrine, Pyridostigmine Bromide, Midodrine + pyridostigmine
- Where
- South Korea
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Rotator Cuff Tear
Treatment of Tendon Injury Using Allogenic Adipose-derived Mesenchymal Stem Cells (Rotator Cuff Tear)
Main purpose of this study is to evaluate efficacy of allogenic adipose-derived mesenchymal stem cells in treatment of tendon injury.
- Trial name
- NCT02298023
- Testing
- allogenic adipose stem cell injection, fibrin glue/normal saline injection, normal saline injection
- Where
- South Korea
- Volunteers
- 24 people
- Sponsor
- Seoul National University Hospital
Dyspnea
Evaluation of Transient Dyspnea During Gadoxetic Acid Enhanced Multiphasic Liver MRI
The purpose of this study is to observe transient dyspnea pattern after Gd-EOB-DTPA administration by obtaining continuous dynamic T1 weighted image data.
- Trial name
- NCT02395991
- Testing
- gadoxetic acid, Magnetic resonance imaging (MRI)
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Seoul National University Hospital
Diabetes Mellitus
The Effect of Dietary Fiber-enriched Cereals on Glycemic Control and Secretion of Gut Hormones
The aim of this study is to assess whether dietary fiber-enriched cereals effect on postprandial glucose levels and plasma glucagon-like peptide 1 (GLP-1) and/or glucose-dependent insulinotropic polypeptide (GIP) concentration in…
- Trial name
- NCT01997281
- Testing
- dietary fiber-enriched cereal, conventional cereal
- Where
- South Korea
- Volunteers
- 28 people
- Sponsor
- Seoul National University Hospital
Deglutition Disorders
Treatment of Dysphagia by Using a Synchronized Electrical Stimulation Device
The purpose of this study is to determine the synchronized electrical stimulation device effective in the treatment of dysphagia.
- Trial name
- NCT02718963
- Testing
- Synchronized Electrical Stimulation Device
- Where
- South Korea
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital