Clinical trials: completed, sponsored by Shirley Ryan AbilityLab
Spinal Cord Injury
Sympathetic-Somatomotor Coupling in Human Spinal Cord Injury
Significance: The long term objective of this study is to improve physical therapy and fitness programs in people with spinal cord injury.
- Trial name
- NCT02115685
- Testing
- Treadmill Training
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Aphasia
Web-Based Treatment for Aphasia
This prospective randomized clinical trial implements an innovative broadband web-based treatment program for individuals with chronic aphasia, and evaluates its efficacy.
- Trial name
- Web-ORLA (NCT04413136)
- Testing
- Web-ORLA, Control
- Volunteers
- 35 people
- Sponsor
- Shirley Ryan AbilityLab
Cerebral Vascular Accident
Implementing a CO-OP Group in the Day Rehab Setting: A Pilot Study.
This is pilot study will examine the effectiveness of a group curriculum developed from the CO-OP approach. This study has two aims, the first is to standardize the group curriculum and the second is to compare the data from the…
- Trial name
- NCT04246385
- Testing
- CO-OP Group
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Shirley Ryan AbilityLab
Post-stroke Shoulder Pain and Spasticity
Randomized DB Controlled Trial of Botulinum Toxin A in Hemiplegic Shoulder Pain and Spasticity
The purpose of this study is to evaluate whether botulinum toxin type A injected into muscles around the shoulder is effective in treating shoulder pain and improving function in patients with shoulder pain and involuntary muscle…
- Trial name
- NCT00661089
- Testing
- Botulinum Toxin Type A - OnabotulinumtoxinA
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Shirley Ryan AbilityLab
Amputation
Adaptive Recalibration of Prosthetic Leg Neural Control System
The purpose of this study is for transfemoral amputees to walk with an experimental robotic prosthesis. Electric signals will be measured from their muscles and used to help control an artificial leg.
- Trial name
- NCT02355912
- Testing
- Powered knee and ankle prosthesis
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Spinal Cord Injury
Identify Training Strategies for Progressing Exoskeleton Users Towards Everyday Functional Ambulation
Many people with spinal cord injury are no longer able to walk and must use wheelchairs for mobility. These individuals experience greater rates of depression and lower quality of life.
- Trial name
- NCT02104622
- Testing
- ReWalk Rehabilitation 2.0
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Shirley Ryan AbilityLab
Stroke
Development of Walk Assist Device to Improve Community Ambulation
Hypothesis/Specific Aims: The purpose of this study is to determine the effect of training with the Stride Management Assist (SMA) device vs.
- Trial name
- NCT01994395
- Testing
- The Stride Management Assist (SMA) System, Impairment based therapy
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Shirley Ryan AbilityLab
Transfemoral Amputees
Thigh Reduction Surgery of Above Knee Amputee Residual Limbs to Improve Prosthesis Fit and Patient Outcomes
The purpose of our study is to improve the fit and function of prosthetic sockets for above the knee amputees through the use of an outpatient thigh reduction surgical procedure.
- Trial name
- NCT02346019
- Testing
- Medial thighplasty with or without thigh liposuction
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Shirley Ryan AbilityLab
Aphasia, Stroke
Enhancing Written Communication in Persons With Aphasia
The purpose of this study is to evaluate whether a computerized speech-language treatment delivered by a virtual therapist (Oral Reading for Language in Aphasia (ORLA) + Writing) results in improved written communication skills…
- Trial name
- NCT01790880
- Testing
- ORLA, ORLA + Writing
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Shirley Ryan AbilityLab
Multiple Sclerosis, Relapsing-Remitting
Acute Intermittent Hypoxia in Persons With Multiple Sclerosis
The overall objective of this project is to investigate the effectiveness of Acute Intermittent Hypoxia (AIH), to improve muscle strength and activity level in individuals with relapsing-remitting MS.
- Trial name
- NCT04280484
- Testing
- Intermittent Hypoxia
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Shirley Ryan AbilityLab
Stroke
Very Intensive Variable Repetitive AmbulatioN Training
The overall objective of this subproject is to evaluate the individual and paired contributions of intensity and variability of stepping training on lower extremity (LE) function, health and community participation in patients…
- Trial name
- VIVRANT (NCT02507466)
- Testing
- exercise
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Shirley Ryan AbilityLab
Transfemoral Amputation, Unilateral Traumatic Amputation of Leg at or Above Knee
Functional Outcomes in Dysvascular Transfemoral Amputees
In older adults, poor circulation in the lower extremities leads to serious health complications including limb loss. In addition, individuals with dysvascular disease also suffer from other co-morbidities like diabetes, coronary…
- Trial name
- CLEG (NCT01537211)
- Testing
- C leg compared to subject's mechanical leg (Otto Bock)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Shirley Ryan AbilityLab
Back Pain
LifeWalker Upright Walker vs. Conventional Rollator Walker and Predicate Device
The purpose of this project is to evaluate if the LifeWalker Upright walker is improves walking and reports of pain compared to a conventional rollator and predicate walker device.
- Trial name
- NCT02968277
- Testing
- LifeWalker Upright, Predicate Device, Standard Rollator
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Shirley Ryan AbilityLab
Stroke
Walk Assist Device to Improve Community Ambulation
The goal of this research study was to examine the immediate effects of a prototype wearable robotic stride management assist device (SMA) designed by Honda R\&D® on clinical walking performance, walking energetics, gait…
- Trial name
- NCT03222505
- Testing
- Honda Stride Assist Device ON, No Device Worn
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Shirley Ryan AbilityLab
Spinal Cord Injuries
Supportive Wheelchair Back Compared to Fabric Back
This study tests using a wheelchair back that supports the spine in a neutral position and one that allows the spine and pelvis to fall into a posterior pelvic tilt.
- Trial name
- NCT03962582
- Testing
- Matrix back
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Shirley Ryan AbilityLab
Stroke
Pushing Behaviors in Individuals Post-stroke
Some individuals demonstrate pushing behaviors after having a stroke. The purpose of this study is to see if there are immediate changes in pushing behaviors in individuals who have had a stroke before and after sitting in a…
- Trial name
- NCT02190734
- Testing
- Sitting in wheel chair, Gait training on treadmill, Gait training overground
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- Shirley Ryan AbilityLab
Stroke, Pulmonary Ventilation
Ventilatory Muscle Training in Stroke
The purpose of the present study is to determine the utility and effectiveness of combined inspiratory (IMT) and expiratory muscle training (EMT) in improving ventilatory function in people who are disabled by long-term stroke…
- Conditions
- Stroke, Pulmonary Ventilation, Exercise Therapy
- Trial name
- NCT02828943
- Testing
- IMT with High Resistance EMT, IMT with Low Resistance EMT
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Shirley Ryan AbilityLab
Aphasia, Stroke
Aphasia Rehabilitation: Modulating Cues, Feedback & Practice
The purpose of this study is to evaluate how changing different conditions of the speech-language treatment (such as cues, feedback, complexity and practice schedule) affects the language outcome of study subjects with aphasia…
- Trial name
- NCT01597037
- Testing
- Script training
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Shirley Ryan AbilityLab
Spinal Cord Injuries
Impact of Intermittent Hypoxia and Prednisolone on Motor Performance in Persons With SCI
The objective of this study is to examine the effects of mild acute intermittent hypoxia (AIH) in combination with an anti-inflammatory drug (i.e. prednisolone) on motor performance in persons with spinal cord injury (SCI).
- Trial name
- NCT03752749
- Testing
- Prednisolone + Acute Intermittent Hypoxia
- Volunteers
- 14 people
- Sponsor
- Shirley Ryan AbilityLab
Amputation, Amputation; Traumatic, Arm, Upper
Comparison of Pattern Recognition Control and Direct Control in TMR
Targeted Muscle Reinnervation increases the control signals available for commercial arm systems. A new type of control, pattern recognition, has been developed into a form that allows use with commercially available arm system.
- Trial name
- NCT03097978
- Testing
- Commercial system, RIC arm system, Direct Control
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Shirley Ryan AbilityLab