Clinical trials: sponsored by St. Olavs Hospital
Tachycardia, Ventricular, Defibrillators, Implantable
Acute Effect of One Single Bout of High Intensity Exercise on the Tendency for Ventricular Arrhythmia
This study will evaluate the acute effect of one single bout of high intensity exercise on the tendency for ventricular arrhythmia.
- Trial name
- NCT04075253
- Testing
- VO2 peak testing
- Where
- Norway
- Volunteers
- 55 people
- Sponsor
- St. Olavs Hospital
Neoplasms
The Orkdal Model. Collaboration Between Specialist and Community Care Within Palliative Cancer Care
The overall aim of this project is to deliver better health care services through improved coordination of cancer care within specialist care (at the local hospital Orkdal Hospital) and community care (13 municipalities in the…
- Trial name
- NCT02170168
- Testing
- integrated palliative care program
- Where
- 25 sites in Norway
- Volunteers
- 969 people
- Sponsor
- St. Olavs Hospital
Carcinoma, Pancreatic Ductal
Ultrasound-enhanced Uptake of Chemotherapy in Patients With Inoperable Pancreatic Ductal Adenocarcinoma
Patients with inoperable pancreatic cancer have extremely poor prognosis with five year survival below 8% in Norway. Life-prolonging chemotherapy has very limited effect, but is the only therapeutic option for these patients.
- Trial name
- PDAC (NCT04146441)
- Testing
- SonoVue, Chemotherapy
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- St. Olavs Hospital
Colorectal Neoplasms, Breast Neoplasms
Ultrasound-enhanced Delivery of Chemotherapy to Patients With Liver Metastasis From Breast- and Colorectal Cancer
The aim of this clinical trial is to investigate whether the therapeutic response of chemotherapy can be improved by focused ultrasound and microbubbles.
- Trial name
- NCT03477019
- Testing
- SonoVue, Focused Ultrasound
- Where
- Norway
- Volunteers
- 17 people
- Sponsor
- St. Olavs Hospital
Cutaneous T-Cell Lymphoma, Unspecified, Chronic Graft Versus Host Disease in Skin
Modification of Extracorporeal Photopheresis in Cutaneous T-cell Lymphoma or Chronic Graft-versus-host Disease
Extracorporeal photopheresis (ECP), is commonly used for the treatment of cutaneous T-cell lymphoma (CTCL) and chronic graft-versus-host disease. ECP (cGVHD) is an immune modulating treatment.
- Trial name
- NCT03109353
- Testing
- ECP with 5-aminolevulinic acid
- Where
- Norway
- Volunteers
- 7 people
- Sponsor
- St. Olavs Hospital
SARS-CoV-2 Acute Respiratory Disease, SARS-CoV-2 Sepsis
The Corona Study of Middle Norway
CUT COVID is a cohort study establised to collect information on patients hospitalized because or with infection by SARS-CoV-2. The cohort data includes clinical data and biological samples from multiple timepoints during…
- Conditions
- SARS-CoV-2 Acute Respiratory Disease, SARS-CoV-2 Sepsis, SARS CoV 2 Infection
- Trial name
- CUT COVID-19 (NCT05638178)
- Testing
- No intervention
- Where
- 5 sites in Norway
- Volunteers
- 223 people
- Sponsor
- St. Olavs Hospital
Jaundice, Neonatal, Hyperbilirubinemia, Neonatal
Identification of Jaundice in Newborns Using Smartphones
Neonatal jaundice is a common and most often harmless condition. However, when unrecognized it can be fatal or cause serious brain injury. Three quarters of these deaths are estimated to occur in the poorest regions of the world.
- Trial name
- NCT04182555
- Testing
- Bilirubin estimates from Smartphone Application, Bilirubin concentration measured in standard blood samples, Bilirubin estimates from standard transcutaneous device
- Where
- 2 sites in Norway
- Volunteers
- 220 people
- Sponsor
- St. Olavs Hospital
Back Pain With Radiation, Pain, Postoperative
Spinal Cord Burst Stimulation for Chronic Radicular Pain Following Lumbar Spine Surgery
Spinal cord stimulation (SCS) is a widely applied therapy to treat chronic neuropathic pain, and one of the most common indications is persisting radicular neuropathic pain following lumbar spine surgery.
- Trial name
- NCT03546738
- Testing
- Burst Spinal Cord Stimulation, SCS implant
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- St. Olavs Hospital
Premature Birth, Respiratory Distress Syndrome, Newborn
Non-invasive Neurally Adjusted Ventilator Assist or Continuous Positive Airway Pressure in Preterm Infants
Strategies to prevent lung injury, facilitate lung development, and to support the preterm infant's capacity to breathe are decisive.
- Trial name
- NCT04333563
- Testing
- CPAP, NIV NAVA
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- St. Olavs Hospital
Spinal Cord Injuries
Living With Spinal Cord Injury.
A Spinal Cord Injury (SCI) often drastically disrupts the lives of affected patients and their relatives and caregivers. This observational study will provide new knowledge on how patients and their family caregivers cope in the…
- Trial name
- NCT03709732
- Testing
- no intervention
- Where
- Norway
- Volunteers
- 2,654 people
- Sponsor
- St. Olavs Hospital
Craniocerebral Trauma, Head Injury, Minor
Exercise in Patients With Post-Concussion Symptoms
Physical activity and exercise have traditionally not been much of a focus in treatment of postconcussion symptoms and posttraumatic headache.
- Conditions
- Craniocerebral Trauma, Head Injury, Minor, Postconcussion Syndrome, Posttraumatic Headache
- Trial name
- NCT04001192
- Testing
- aerobic exercise program
- Where
- Norway
- Volunteers
- 30 people
- Sponsor
- St. Olavs Hospital
Mental Disorder
Testing the Effectiveness of an Evening Blue-depleted Light Environment in an Acute Psychiatric Ward
There is increasing recognition of the need to stabilize sleep-wake cycles in individuals with major mental disorders. As such, clinicians and researchers advocate for the use of interventions targeted at sleep and circadian…
- Trial name
- NCT03788993
- Testing
- Blue-depleted evening light condition, Normal light condition
- Where
- Norway
- Volunteers
- 475 people
- Sponsor
- St. Olavs Hospital
Cerebral Palsy, Muscle Spasticity
Does Botulinum Toxin A Make Walking Easier in Children With Cerebral Palsy?
In Norway, about 60% of all children with cerebral palsy (CP) are being treated with botulinum toxin A (BoNT-A) at 6 years of age, mainly in the legs.
- Trial name
- WE (NCT02546999)
- Testing
- botox
- Where
- 7 sites in France, Norway and 1 more
- Volunteers
- 61 people
- Sponsor
- St. Olavs Hospital
Heart Diseases
The Impact of Noradrenaline on Ventriculo-arterial Coupling and Central Cardiovascular Energy Delivery
The study aims to examine how noradrenaline in combination with venous return influences the energy transmission from heart to central circulation and arteries - also called arterio-ventricular coupling.
- Trial name
- NCT04745845
- Testing
- Noradrenalin
- Where
- Norway
- Volunteers
- 49 people
- Sponsor
- St. Olavs Hospital
Pelvic Organ Prolapse, Pelvic Floor Disorders
Pelvic Floor Exercise Before Surgery in Women With Pelvic Organ Prolapse
The lifetime risk for a woman to undergo surgery for either vaginal prolapse or urinary incontinence is high. There are many different surgical techniques for treatment of prolapse, but there is a lack of knowledge about factors…
- Trial name
- CONTRAPOP (NCT03064750)
- Testing
- pelvic floor exercises, Waiting list
- Where
- Norway
- Volunteers
- 151 people
- Sponsor
- St. Olavs Hospital
Attention Deficit Disorder With Hyperactivity
Cognitive Behavior Group Therapy in Adolescents With Attention Deficit Hyperactivity Disorder
Attention Deficit Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder which starts in childhood and is characterized by symptoms of attention deficit, hyperactivity and impulsivity.
- Trial name
- NCT02937142
- Testing
- cognitive behavior group therapy, Treatment as usual
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- St. Olavs Hospital
Brain Injuries
Cognitive Rehabilitation in Pediatric Acquired Brain Injury
Acquired brain injury (e.g., traumatic brain injury, brain tumour, brain infections) is one of the leading causes of death and disability for children and adolescents.
- Trial name
- CORE-pABI (NCT03215342)
- Testing
- Pediatric Goal Management Training, Pediatric Brain Health Workshop
- Where
- 2 sites in Norway
- Volunteers
- 76 people
- Sponsor
- St. Olavs Hospital
Joint Diseases
Depot-opioids for Pre- and Postoperative Pain Relief After Primary Knee Arthroplasty.Tapentadol vs Oxycodone vs Placebo
This study will provide knowledge about the use of long-acting opioids for pain relief after primary knee arthroplasty. The investigators will compare depot tapentadol, depot oxycodone and placebo for effect on pain relief and…
- Trial name
- NCT02604446
- Testing
- Tapentadol, Oxycodone, usual pain treatment
- Where
- Norway
- Volunteers
- 134 people
- Sponsor
- St. Olavs Hospital
Cerebral Palsy
The Small Step Program - Early Intervention for Children With High Risk of Developing Cerebral Palsy
Children with cerebral palsy (CP) have life-long motor disorders caused by brain injuries which occur around birth. These children go through extensive treatment during childhood, but the treatment has generally been started late…
- Trial name
- NCT03264339
- Testing
- Small Step Program
- Where
- Norway
- Volunteers
- 12 people
- Sponsor
- St. Olavs Hospital
Sleep, Insomnia
Pharmacological Treatment of Insomnia in Palliative Care
Sleep disturbance is frequent in patients with advanced cancer and decreases the tolerability of other symptoms and impairs quality of life.
- Trial name
- NCT02807922
- Testing
- Zopiclone
- Where
- 5 sites in Norway
- Volunteers
- 43 people
- Sponsor
- St. Olavs Hospital