Clinical trials: sponsored by The Hong Kong Polytechnic University
Frailty, Frailty in Older Adults
ENRICH Study: A Mixed-methods Feasibility Study of a Nurse-led Model of Care for Social Frailty in Philippine Primary Care
The ENRICH Study is a single-arm, single-site, mixed-methods feasibility and pilot implementation study examining a culturally adapted, nurse-led model of care for social frailty among community-dwelling older adults in one…
- Conditions
- Frailty, Frailty in Older Adults, Frailty in Aging
- Trial name
- ENRICH (NCT07861997)
- Testing
- Group activities (i.e., low impact exercise), peer counseling, volunteering, Social Frailty Care Bundle (SFCB)
- Where
- Philippines
- Volunteers
- 30 people
- Sponsor
- The Hong Kong Polytechnic University
Fall Prevention in Healthy Aging, Fall
Effect of LiFE-SePBT on Postural Stability in Community-dwelling Older Adults: an Assessor-blinded Randomised Controlled Trial
This study is an assessor-blinded randomised controlled trial investigating the effects of combined Lifestyle-integrated Functional Exercise and Self-initiated Perturbation-based Balance Training (LiFE-SePBT) on postural…
- Conditions
- Fall Prevention in Healthy Aging, Fall, Fall Prevention Training, Postural Control
- Trial name
- LiFE-SePBT (NCT07842094)
- Testing
- Lifestyle-integrated Functional Exercise, Upper limb mobilisation and flexibility training
- Where
- Hong Kong
- Volunteers
- 44 people
- Sponsor
- The Hong Kong Polytechnic University
Resilience
Partial Digitalization of Mission ReST
The goal of this non-randomized trial is to partially digitalize and develop a web-based resilience-building intervention and pilot-test its feasibility, acceptability, and appropriateness in an undergraduate sample over a…
- Trial name
- NCT07851792
- Testing
- Digitalized Session 1 of Mission ReST, In-person delivery of Mission ReST Session 1
- Where
- Hong Kong
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Frailty at Older Adults, Mild Cognitive Impairment
A Novel Multi-Modal Approach to Promote Functional Outcomes in Cognitively Frail Older Adults
The goal of this clinical trial is to explore the effects of intermittent theta burst stimulation (iTBS) primed with theta burst stimulation (cTBS), on top of aerobic exercise, on cognitive function, mobility, and brain activity…
- Trial name
- TMS MRI TBS (NCT07497334)
- Testing
- Theta burst stimulation, Aerobic exercise
- Where
- Hong Kong
- Volunteers
- 45 people
- Sponsor
- The Hong Kong Polytechnic University
Stroke
Effect of Combining Central and Peripheral Cutaneous Electrical Stimulation on Lower Limb Motor Function in People With Stroke
This study aims to evaluate the effectiveness of transcranial direct current stimulation (tDCS) and transcutaneous electrical nerve stimulation (TENS) in augmenting the efficacy of the lower limb task-oriented training in people…
- Trial name
- NCT06838013
- Testing
- Transcranial direct current stimulation (tDCS), Bilateral Transcutaneous electrical nerve stimulation (Bi-TENS), Lower-limb task-oriented training
- Where
- Hong Kong
- Volunteers
- 92 people
- Sponsor
- The Hong Kong Polytechnic University
Depression
Neurophysiological RCT of Qigong in Elderly With Depression
Summary of Project: Elderly depression is a common mood disorder and the individuals will have persistent low mood and self-absorption that adversely affect their quality of life.
- Trial name
- NCT05000788
- Testing
- Qigong, Exercise
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- The Hong Kong Polytechnic University
Intermittent Exotropia
Near Vergence Training for Distance Control in Intermittent Exotropia
Intermittent Exotropia (IXT) is a common type of eye misalignment where one eye periodically turns outward, and control is typically much worse when looking at objects far away than close up.
- Trial name
- NCT07642687
- Testing
- Home-based near eye training program
- Where
- Hong Kong
- Volunteers
- 42 people
- Sponsor
- The Hong Kong Polytechnic University
Transcranial Direct Current Stimulation, Post-Concussion Syndrome
Effects of tDCS for Enhancing Cognitive Function in Individuals With Persistent Post-Concussion Syndrome
Globally, 10 million new traumatic brain injury (TBI) cases are estimated annually, with mild traumatic brain injury (mTBI) accounting for 75-90% of all TBI cases.
- Conditions
- Transcranial Direct Current Stimulation, Post-Concussion Syndrome, Functional Magnetic Resonance Imaging, Magnetic Resonance Spectroscopy
- Trial name
- NCT06376500
- Testing
- tDCS with cognitive training programme
- Where
- Hong Kong
- Volunteers
- 40 people
- Sponsor
- The Hong Kong Polytechnic University
Insomnia, Healthy Adult
The Impact of Insomnia on Pain Sensitivity and the Trajectory of Exercise-induced Muscular Pain
Sleep is a critical determinant of physiological recovery and pain regulation. Growing evidence suggests that sleep disruption directly heightens central and peripheral pain sensitivity to sensory stimuli (e.g., mechanical…
- Conditions
- Insomnia, Healthy Adult, Musculoskeletal Pain, Pain Sensitivity
- Trial name
- NCT07827664
- Testing
- Eccentric exercise
- Where
- Hong Kong
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Autism Spectrum Disorder (ASD), Transcranial Direct Current Stimulation (tDCS)
Resting-State Functional Connectivity as a Predictor of tDCS Effects in Adolescents With Autism Spectrum Disorder
Background: Transcranial Direct Current Stimulation (tDCS) is a form of non-invasive brain stimulation that has aroused increased interests in the past decade.
- Conditions
- Autism Spectrum Disorder (ASD), Transcranial Direct Current Stimulation (tDCS), Electroencephalography
- Trial name
- NCT06878326
- Testing
- tDCS
- Where
- Hong Kong
- Volunteers
- 90 people
- Sponsor
- The Hong Kong Polytechnic University
Insomnia, Healthy Adult
The Impact of Acute Pain on Sleep Parameters in the Insomnia Population and Healthy Controls
This study investigates how acute exercise-induced muscular pain affects sleep quality and sleep architecture in people with insomnia compared to healthy sleepers.
- Conditions
- Insomnia, Healthy Adult, Sleep, Musculoskeletal Pain
- Trial name
- NCT07826650
- Testing
- Eccentric exercise
- Where
- Hong Kong
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Dry Eye Syndromes
Efficacy of Lycium Barbarum Polysaccharide in Dry Eye Disease Management
The goal of this pilot clinical study is to learn if Lycium barbarum polysaccharide (LBP) supplementation helps manage dry eye disease in adults. It will also learn about the safety of LBP supplementation.
- Trial name
- NCT07842536
- Testing
- Lycium Barbarum Polysaccharide
- Where
- Hong Kong
- Volunteers
- 30 people
- Sponsor
- The Hong Kong Polytechnic University
Frailty at Older Adults
Enhancing Physical Reserve to Promote Resilience in Physically Frail Older Adults
The goal of this clinical trial is to assess the efficacy of combined aerobic and resistance training in enhancing physical reserve in older adults with physical frailty.
- Trial name
- MRI exercise (NCT07513701)
- Testing
- Aerobic and resistance training, Usual Care
- Where
- Hong Kong
- Volunteers
- 224 people
- Sponsor
- The Hong Kong Polytechnic University
Dementia, tDCS
The Efficacy of HD-tDCS-Augmented Step Training in Older Adults With Mild Dementia
Falls and mobility decline are major health concerns among older adults with dementia, often linked to deterioration in executive function and cognitive-motor control.
- Conditions
- Dementia, tDCS, Physical Exercise, Neuromodulation
- Trial name
- NCT07841145
- Testing
- Step training, active HD-tDCS
- Where
- Hong Kong
- Volunteers
- 68 people
- Sponsor
- The Hong Kong Polytechnic University
Insomnia, Adults
A Theory-based Sleep Hygiene Education for Insomnia Patients
Insomnia is a prevalent sleep disorder associated with substantial negative health consequences, including fatigue, irritability, and impaired daytime functioning.
- Trial name
- NCT07559305
- Testing
- Sleep Hygiene Education
- Where
- Hong Kong
- Volunteers
- 11 people
- Sponsor
- The Hong Kong Polytechnic University
Insomnia, Adults
A Theory-based Sleep Hygiene Education for Insomnia Disorder
Insomnia is a prevalent sleep disorder associated with numerous adverse health outcomes, including fatigue, irritability, and impaired daytime functioning.
- Trial name
- NCT07642479
- Testing
- Sleep Hygiene Education, CBT-I Apps
- Where
- Hong Kong
- Volunteers
- 264 people
- Sponsor
- The Hong Kong Polytechnic University
Insomnia, Perimenopausal Women
Self-acupressure for Insomnia in Perimenopausal Women
Insomnia is a common complaint in peri-menopausal women. Acupressure might be a potential way to treat insomnia. Although acupressure can be self-administered, it is uncertain that whether the effects of self-administered…
- Trial name
- SAP (NCT06463197)
- Testing
- Self-Administered Acupressure Group, Sleep Hygiene Education group
- Where
- Hong Kong
- Volunteers
- 40 people
- Sponsor
- The Hong Kong Polytechnic University
Healthy Male and Female Subjects
Validation Study of an Assistive Pulse Data Collection Device
Background: Traditional Chinese Medicine (TCM) relies on pulse diagnosis, a subjective and complex method that is crucial for assessing patients' health status.
- Trial name
- NCT06974227
- Testing
- Assistive Pulse Data Collection (APDC) Device
- Where
- Hong Kong
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Chronic Nonspecific Neck Pain
Comparative Effectiveness Randomised Controlled Trial of Hybrid Muscle Conditioning
Chronic nonspecific neck pain is a prevalent and recurrent condition frequently characterised by persistent impairments in cervical-scapular neuromuscular function.
- Trial name
- NCT07837414
- Testing
- Hybrid exercise group, Motor control exercise group, Endurance exercise group
- Where
- Hong Kong
- Volunteers
- 210 people
- Sponsor
- The Hong Kong Polytechnic University
Older Adults Living in Residential Care Facilities
The Assisted Lifestyle-Intergrated Functional Exercise Program in Older Adults Living in Residential Care Facilities
More than half of older adults living in care homes experience a fall each year, which can cause serious injuries, hospital visits, and a loss of independence.
- Trial name
- ALIFE (NCT07835503)
- Testing
- ALIFE exercise program, OTAGO exercise program
- Where
- Hong Kong
- Volunteers
- 49 people
- Sponsor
- The Hong Kong Polytechnic University