Clinical trials: sponsored by University Hospital, Brest
Forefoot Adductus, Cerebral Palsy
Deformity of the Forefoot in Children With Unilateral Cerebral Palsy
Midfoot and backfoot deformities are well described in children with Cerebral palsy. However, data regarding forefoot deformities in Cerebral palsy remain scarce in a population were foot deformities are the most frequent…
- Trial name
- Mediopied-PC (NCT05662046)
- Where
- 2 sites in France
- Volunteers
- 52 people
- Sponsor
- University Hospital, Brest
Emergencies, Pediatric ALL
Pediatric Telephone Center Board 15
This study evaluates the follow-up of advices given in a Urgent Medical Aid Service (SAMU 29) for every pediatric's emergency call under 15yo and try to evaluate the adhesion's factors.
- Conditions
- Emergencies, Pediatric ALL, Response, Acute Phase
- Trial name
- CTPC15 (NCT05642117)
- Where
- France
- Volunteers
- 785 people
- Sponsor
- University Hospital, Brest
SBRT, Non-small Cell Lung Cancer
Lung Perfusion PET / CT Using Ga68-MAA for Preservation of Lung Function During Stereotactic Pulmonary Radiation Therapy
This is a prospective study evaluating the feasibility of treatment planning integrating lung perfusion PET/CT using Ga68-MAA to preserve functional lung areas during stereotactic body radiation therapy (SBRT).
- Conditions
- SBRT, Non-small Cell Lung Cancer, Lung Metastasis
- Trial name
- PEGASUS (NCT04942275)
- Testing
- Pre-therapeutic imaging test
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Brest
Cardiac Arrest, Doppler Ultrasound
Doppler Ultrasound in Rewarming After Targeted Control Management in Cardiac Arrest
The aim of the study is to describe CBF modifications during rewarming after targeted temperature management in cardiac arrest patients
- Trial name
- DTCHT (NCT03160417)
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Brest
Vancomycin Dosage
External Evaluation of Vancomycin Population Pharmacokinetic Models
All patients treated with vancomycin hospitalized outside of ICU in Brest University Hospital from 1rst january 2019 to 1rst january 2021 will be screened for inclusion.
- Trial name
- EOPMV (NCT05481788)
- Where
- France
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Transplant; Complication, Failure
Evaluation at 5 and 10 Years of Renal Transplant Patients
5 and 10 years follow-up of the oxyop study.
- Trial name
- OXYOP 5 and 10 (NCT05469906)
- Where
- France
- Volunteers
- 116 people
- Sponsor
- University Hospital, Brest
Hip Arthritis
Is a THA Stem in Varus a Risk Factor of Long-term Mechanical Complication
The objective of this study is to compare the long-term survival as well as the functional and radiographic results of the rods in the alignment of the varus to the stems in the neutral alignment by comparing 2 groups of…
- Trial name
- PTHVarus (NCT05443243)
- Testing
- Total Hip Arthroplasty
- Where
- France
- Volunteers
- 210 people
- Sponsor
- University Hospital, Brest
Venous Thromboembolism
The SYMPTOMS - SYstematic Elderly Medical Patients Thromboprophylaxis: Efficacy on Symptomatic OutcoMeS - Study
Venous thromboembolism (VTE) is a frequent condition, affecting 1.8 per 1,000 people every year. Admission to hospital is one of the main risk factors for VTE, and could account for up to 20% of all VTE, making VTE prevention in…
- Trial name
- SYMPTOMS (NCT02379806)
- Testing
- Enoxaparin
- Where
- 46 sites in France, Switzerland
- Volunteers
- 2,560 people
- Sponsor
- University Hospital, Brest
ICU Delirium
Dexmedetomidine After Cardiac Surgery for Prevention of Delirium
We designed a prospective, double blind, randomized, controlled versus placebo study to evaluate the efficacy of nightly low dose of Dexmedetomidine infusion to promote sleep and lower delirium in a population of post cardiac…
- Trial name
- EXACTUM (NCT03477344)
- Testing
- Dexmedetomidine, Sodium chloride 0.9%
- Where
- 9 sites in France
- Volunteers
- 348 people
- Sponsor
- University Hospital, Brest
ANCA Associated Vasculitis, Occupational Diseases
Occupational and Environmental Origins of ANCA Vasculitis: Contribution of Data From the National Network for Vigilance and Prevention of Occupational Pathologies (RNV3P)
The main objective is to identify specific risk factors for ANCA vasculitis of occupational and/or environmental origin (exposures identified by questioning, geographical distribution of cases) from the RNV3P data.
- Conditions
- ANCA Associated Vasculitis, Occupational Diseases, Environmental Exposure
- Trial name
- ANCAPRO (NCT05416723)
- Where
- 11 sites in France
- Volunteers
- 302 people
- Sponsor
- University Hospital, Brest
Uveitis
Retrospective Comparison of the Efficacy of Methotrexate and Azathioprine as Background Treatment for Uveitis of Undetermined Origin: Single-centre Retrospective Study From 2005 to 2020
Retrospective study at the Brest universitary hospital to evaluate the efficacy of methotrexate (MTX) and azathioprine (AZA) in background treatment of unidentified non anterior uveitis.
- Trial name
- UMetAza (NCT05370690)
- Where
- France
- Volunteers
- 70 people
- Sponsor
- University Hospital, Brest
Effects of Welding Fumes Components
Study of the Impact of Welding Fumes on the Arterial System : RISCAS Study
Metals and oxydes are found in welding fumes and are thought to participate in increasing cardiovascular risk in exposed workers.
- Trial name
- RISCAS (NCT03281239)
- Testing
- Laser doppler, blood tests, and holter ECG
- Where
- France
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Muscle Injury
IS ElastomEtry Useful in Muscle Lesion evaluaTion-REPROducibility Study
Our objective is to evaluate the inter and intra observer reproducibility of the measure of elasticity using Acoustic Radiation Force Impulse (ARFI) ultrasonography of mucles of patients with and without hamstring injury.
- Trial name
- ISEULT-Repro (NCT05361928)
- Where
- France
- Volunteers
- 31 people
- Sponsor
- University Hospital, Brest
Gut Feelings
Assessment of "Gut Feelings" Accuracy Regarding the Effect of Professional Experience in General Practitioners in Clinical Decision Making
Knowledge, experience and professional development limit the risk of diagnostic error for the clinician in daily practice. However, research has shown that other non-analytical factors are involved in clinical decision making.
- Trial name
- EGFGP (NCT05175157)
- Testing
- Gut Fellings questionnaire
- Where
- France
- Volunteers
- 260 people
- Sponsor
- University Hospital, Brest
Fibromyalgia
Impact of a Specific Training Program on the Neuromodulation of Pain in Fibromyalgia Subjects
Fibromyalgia affects 1.4 now 2.2% of the general population whose symptom is the presence of widespread pain in all four quadrants of the body. Currently, there is no causal treatment of fibromyalgia syndrome.
- Trial name
- DOUFISPORT (NCT02486965)
- Testing
- thermode (TSA-II model), Adapted Physical Activity, Physical activity
- Where
- 2 sites in France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Brest
Carcinoma, Non-Small-Cell Lung, Immunotherapy
Efficacy and Safety of PEMbrolizumab PD-L1-positive (>50% of Tumor Cells), Advanced NSCL Cancer(PEMBREIZH)
This study was a French multicentric cross-sectional study retrospectively of 108 consecutive advanced NSCLC patients with a PD-L1 TPS ≥50% and without EGFR/ALK aberrations treated by pembrolizumab in first line.
- Trial name
- PEMBREIZH (NCT05321212)
- Where
- 2 sites in France
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Depression
Adolescent Depression Associated With Parental Depression
Depression is difficult to identify, prevent and treat in adolescents because of complex and stigmatized multiform symptoms and pathways of care.
- Trial name
- AdoDesP (NCT03811041)
- Testing
- MDA, Routine Cares, Parental depression
- Where
- 12 sites in France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Brest
Children With Disabilities; Motor Rehabilitation; Technologies
Motor REHAbilitation TEChnologies for CHIldren With Disability: A Cross-European Survey
The aim of the RehaTech4Child survey led by EACD is to identify the digital technologies (e.g., robotic devices and treadmill systems, virtual reality and gaming systems, telehealth) that are used in clinical practices throughout…
- Trial name
- RehaTech4Child (NCT05176522)
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Brest
Polymyalgia Rheumatica, Sjogren's Syndrome
Polymyalgia Rheumatica Associated to Primary Sjogren Syndrome
To determine the phenotype of patients having PMR symptoms and primary Sjogren syndrome (pSS), we used a French national call to identify patients combining both diseases and collected retrospective clinical and biological data.
- Trial name
- PASS (NCT05312944)
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Brest
Children, Disabilities
InnovationForParticipation
Children with disabilities experience activities limitations and participation restrictions. Facilitating the children with disabilities' independence while performing tasks is a key stake to improve their successful…
- Trial name
- I4P (NCT05103930)
- Where
- France
- Volunteers
- 1,055 people
- Sponsor
- University Hospital, Brest