Clinical trials: sponsored by University of Aarhus
Healthy Children, Children
Improvements in Daily Activity and Exercise in School Children: the ActChild Study
The goal of this clinical trial is to assess the health-related effects of an exercise intervention in children aged 5-8 years. Main research questions: Does a municipality-driven exercise intervention improve physical activity…
- Conditions
- Healthy Children, Children, Children in School, Child Health
- Trial name
- ActChild (NCT06791278)
- Testing
- Exercise
- Where
- Denmark
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Liver Cirrhosis
Faecal Microbiota Transplantation for Liver Cirrhosis
The purpose is to investigate the effect of faecal microbiota transplantation (FMT) on complications, progression, and mortality of patients with liver cirrhosis.
- Trial name
- CHiFT (NCT04932577)
- Testing
- Faecal microbiota transplantation
- Where
- Denmark
- Volunteers
- 220 people
- Sponsor
- University of Aarhus
Minimal Change Disease, Nephrotic Syndrome
Active Vitamin D And Reduced Dose Prednisolone for Treatment in Minimal Change Nephropathy
Traditionally MCN is treated with a high dose of prednisolone, which induces remission in 60-90% of patients. Prednisolone treatment contains numerous side effects and the current dose is empiric.
- Trial name
- ADAPTinMCN (NCT03210688)
- Testing
- Prednisolone, Alfacalcidol
- Where
- 2 sites in Denmark
- Volunteers
- 71 people
- Sponsor
- University of Aarhus
Dental Plaque
Automated Quantification of Dental Plaque
The study generates data that contribute to the development and validation of an automated approach to full-mouth quantification of dental plaque, based on fluorescence images and intraoral scans of teeth with disclosed and…
- Trial name
- NCT06789835
- Testing
- Fluorescence imaging of disclosed and undisclosed plaque
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Diabetes Mellitus, Type 2
Specialist Conferences Between General Practitioners and Endocrinologists
To support the primary care sector in delivering high-quality Type 2-diabetes (T2D), literature reviews emphasize the need for implementing models of collaboration that in a simple and effective way facilitate clinical dialogue…
- Trial name
- STAR (NCT05268081)
- Testing
- Virtual specialist conferences
- Where
- Denmark
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Polyneuropathy, Alpha-Synucleinopathy
Prodromal Model of Parkinson's Disease Confined to The Peripheral Nervous System
Description of a method to detect Parkinson's disease or Parkinson's-like disease at an early stage (Prodromal Parkinson's Disease) where damage is still confined to the peripheral nervous system damage.
- Conditions
- Polyneuropathy, Alpha-Synucleinopathy, Lewy Body Disease, Parkinson Disease (PD)
- Trial name
- Prompark (NCT06745011)
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- University of Aarhus
Dental Plaque, Dental Caries
Probiotic Treatment of Orthodontic Patients
The purpose of this study is to examine the effect of treatment with a lozenge containing the probiotic strain S. salivarius M18 on the formation, composition and virulence of dental plaque and in healthy orthodontic patients…
- Trial name
- NCT06751979
- Testing
- Probiotic treatment
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Dental Caries, Dental Plaque
The Effect of Arginine on Biofilm Composition, Architecture and Metabolism
Arginine is an adjunct to oral health care that has the potential to modulate the composition and activity of the microbial community of dental biofilms towards a health-related status without harmful effects for the resident…
- Conditions
- Dental Caries, Dental Plaque, Microbial Colonization
- Trial name
- NCT06135792
- Testing
- Arginine
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- University of Aarhus
Multiple Sclerosis
Exercise Booster Sessions in People With Multiple Sclerosis
This study wants to investigate whether exercise booster sessions applied in the follow-up period after an exercise intervention can increase the sustainability of exercise induced effects in persons with multiple sclerosis.
- Trial name
- NCT04913012
- Testing
- Systematic aerobic training, Systematic resistance training, Aerobic training booster sessions
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- University of Aarhus
Hepatocellular Carcinoma
A Head-to-head Comparison of MRI, CT, 18F-FDGal and 18F-choline in Patients With Hepatocellular Carcinoma
Hepatocellular carcinoma (HCC) is the most common primary liver tumour and is the fourth leading cause of cancer-related death worldwide.
- Trial name
- NCT05359939
- Testing
- 18F-FDGal PET/CT versus 18F-choline PET/CT
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- University of Aarhus
Hepatocellular Carcinoma
18F-FDGal PET/CT and PET/MRI in Patients With Hepatocellular Carcinoma
Hepatocellular carcinoma (HCC) is the most common primary liver tumor and the fourth leading cause of cancer-related death worldwide.
- Trial name
- NCT05871892
- Testing
- 18F-FDGal PET/CT or PET/MRI
- Where
- Denmark
- Volunteers
- 125 people
- Sponsor
- University of Aarhus
HPV, Complex Intervention
Schoolbased HPV-counselling and -Vaccination
This study is designed as a non-randomized implementation study consisting of a user-centered school-based HPV-counselling and HPV-vaccination (HPVV) program.
- Trial name
- NCT05681169
- Testing
- School-based HPV-counselling and HPV-vaccination.
- Where
- Denmark
- Volunteers
- 640 people
- Sponsor
- University of Aarhus
Preterm Birth, Preterm Premature Rupture of Membrane
Amniochorionic Membrane Cells in the Maternal Blood as a Biomarker for Preterm Birth
Globally, preterm birth (15 mill. per year) is the leading cause of under-5 child mortality (1 mill. per year) and morbidity. Important pathways include preterm labor contractions, Preterm Prelabor Rupture of the Fetal Membranes…
- Conditions
- Preterm Birth, Preterm Premature Rupture of Membrane, Preterm Labor
- Trial name
- NCT04705935
- Where
- Denmark
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Esophageal Cancer, Radiotherapy
PROton Versus Photon Therapy for Esophageal Cancer - a Trimodality Strategy
The PROTECT trial will test the hypothesis that proton (PT) -enabled radiation dose reductions to sensitive, normal tissues will result in lower rates of treatment-related pulmonary complications in esophageal cancer compared to…
- Conditions
- Esophageal Cancer, Radiotherapy, Side Effect, Proton Therapy
- Trial name
- PROTECT (NCT05055648)
- Testing
- Photon Radiotherapy, Proton Radiotherapy
- Where
- 15 sites in Belgium, Denmark and 6 more
- Volunteers
- 396 people
- Sponsor
- University of Aarhus
Faecal Microbiota Transplantation (FMT), Diabetes Mellitus, Type 1
Faecal Microbiota Transplantation for Patients With Diabetes Mellitus Type 1 and Severe Gastrointestinal Neuropathy
A randomised, double-blinded and placebo-controlled intervention study. The study aim to evaluate the feasibility, safety and pilot-efficacy of faecal microbiota transplantation as a treatment of severe gastrointestinal…
- Conditions
- Faecal Microbiota Transplantation (FMT), Diabetes Mellitus, Type 1, Gastrointestinal Neuropathy
- Trial name
- Fadigas (NCT04749030)
- Testing
- Faecal microbiota transplantation (FMT) capsules
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- University of Aarhus
Diaphragm Disease
Replaceability of Fluoroscopy and Ultrasound in the Evaluation of Hemidiaphragm Excursion
Precise measurement of diaphragm function is difficult. Several methods exist. No are sufficiently validated. With this study, the investigators wish to investigate the validity of different ultrasound and radiological methods…
- Trial name
- NCT04098939
- Testing
- Diaphragm evaluation
- Where
- Denmark
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Multiple Sclerosis
Resistance Training and Corticospinal Excitability in Multiple Sclerosis
The goal of the present study is to investigate effects of progressive resistance training on central nervous system functioning (corticospinal excitability (CSE)) and walking capacity in persons with multiple sclerosis (pwMS).
- Trial name
- NEXIMS (NCT06374108)
- Testing
- Progressive resistance training
- Where
- 2 sites in Denmark
- Volunteers
- 54 people
- Sponsor
- University of Aarhus
Preterm Birth, Cervical Insufficiency
Nordic Randomized Trial on Laparoscopic Versus Vaginal Cerclage
Every year 15 million babies are born prematurely, which can lead to death or life-long disabilities. It is often caused by a dysfunction of the uterine cervix, which constitutes the narrow channel between the vagina and womb.
- Trial name
- NORACT (NCT06122506)
- Testing
- Laparoscopic cerclage, Vaginal cerclage
- Where
- 2 sites in Denmark
- Volunteers
- 188 people
- Sponsor
- University of Aarhus
Healthy Participants
Prevention of Hazardous Use of Alcohol with Danish High School Students (Our Choice)
The trial 'Our Choice' examines the effect of two prevention interventions targeting school, parent, and student levels at Danish high schools.
- Trial name
- NCT06018389
- Testing
- Structural only, Structural+Group MI
- Where
- Denmark
- Volunteers
- 3,100 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Chronic Cluster Headache, Primary Headache Disorder
Treatment of Chronic Cluster Headache with TENS and ONS
The study is an investigator-initiated, prospective, randomized, placebo-controlled, double blind clinical trial that aims to investigate the effect of transcutaneous electrical nerve stimulation (TENS) and occipital nerve…
- Conditions
- Chronic Cluster Headache, Primary Headache Disorder, Headache, Cluster Headache
- Trial name
- HortONS (NCT05023460)
- Testing
- Paresthesia-free (burst) ONS
- Where
- Denmark
- Volunteers
- 38 people
- Sponsor
- University of Aarhus
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