Clinical trials: sponsored by University of Aarhus
Brain Tumor, Cognitive Impairment
Cerebral Morbidity After Radiation Therapy for Brain Tumors
This study will assess cognitive function in patients with a primary brain tumour treated with radiation therapy (RT) to generate radio-sensitivity and volume effect parameters for the development of cognitive dysfunction.
- Conditions
- Brain Tumor, Cognitive Impairment, Radiation Toxicity
- Trial name
- WP-12 (NCT04292353)
- Testing
- Cognitive tests and Patient Reported Outcome
- Where
- 4 sites in Denmark
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Overweight Adolescents, Metabolic Disease
Breakfast for Female Adolescent - NewStart
Investigators will test the long-term health effects of eating a dairy-based protein-rich breakfast and/or performing regular physical training for 12 weeks in 100 previous 'breakfast skipping' young overweight women (2 x 2…
- Trial name
- NewStart (NCT04419415)
- Testing
- Breakfast with high protein dairy, Exercise training, Skipping breakfast
- Where
- Denmark
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Hypochondriasis
Internet-delivered Acceptance and Commitment Therapy for Patients With Health Anxiety
Health anxiety is a prevalent, disabling disorder associated with extensive health care expenditures. The lack of easily accessible, evidence-based psychological treatment combined with delayed diagnostic recognition constitute…
- Trial name
- NCT02735434
- Testing
- Internet-based ACT, Internet-based discussion forum
- Volunteers
- 101 people
- Sponsor
- University of Aarhus
Frail Elderly Syndrome, Transitional Care
Models of Care in the Transition From the Secondary to the Primary Sector Among the Frailest Elderly
In most Western countries the elderly population increases rapidly. In Denmark, the population of elderly aged 75 years or older may amount to nearly 15 % of the entire population in 2050 compared to 9 % today (2017).
- Conditions
- Frail Elderly Syndrome, Transitional Care, Frailty, Readmission
- Trial name
- NCT03796923
- Testing
- Early follow-up visit after discharge, Comprehensive geriatric assessment (CGA), Continued geriatric care
- Where
- Denmark
- Volunteers
- 3,340 people
- Sponsor
- University of Aarhus
Osteoporosis, Postmenopausal
The Effects of Melatonin Treatment on Bone, Marrow, Sleep and Blood Pressure
Melatonin protects your bones while losing fat! This was previously demonstrated by our group. The mechanisms behind these findings are still elusive, and the aim of the present study is to assess the mechanisms.
- Trial name
- NCT04864509
- Testing
- Melatonin 10 MG
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Alcoholic Hepatitis
Protective Immune Mechanisms in Alcoholic Hepatitis
The purpose of this study is to investigate the production, effects and interactions of the hepato-protective cytokine interleukine (IL)-22 in patients with alcoholic hepatitis.
- Trial name
- AHIL (NCT01918462)
- Where
- Denmark
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Neuropathy;Peripheral, Thermal Hypesthesia
Effect of Topical Lidocaine on Warm and Cold Sensation in Healthy Individuals
The purpose of the present study is to systematically test the occurrence of paradoxical and illusory responses to cold and warm stimuli in healthy volunteers with artificial sensory loss.
- Trial name
- NCT04865185
- Testing
- Xylocaine spray 100mg/ml, Ethanol
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Inflammatory Response, Symptoms and Signs
CANDLE - A Study of Acute Health Effects of Exposure to Particles Generated by Candles
INTRODUCTION: Particle contamination is suggested to have substantial negative effects on health, with candles emitting huge amount of particles, thus being one of the largest contributors to indoor air pollution.
- Trial name
- NCT04864600
- Testing
- Candle C, Candle 1
- Where
- Denmark
- Volunteers
- 17 people
- Sponsor
- University of Aarhus
Carcinoma, Hepatocellular, Neuroendocrine Tumors
Circulating Tumor Cells and Tumor DNA in HCC and NET
Background Treatment and control of cancer is associated with high costs, to patients in the form of side effects and discomfort during investigations, to society in the form of expensive drugs and studies.
- Trial name
- NCT02973204
- Testing
- Sorafenib, Radiofrequency ablation (RFA) or surgery, Everolimus
- Where
- Denmark
- Volunteers
- 167 people
- Sponsor
- University of Aarhus
Pulmonary Embolism
Low Dose Catheter Directed Thrombolysis for Acute Pulmonary Embolism
BETULA trial will compare the efficacy of low dose catheter directed thrombolysis (CDT) to unfractioned heparin (UFH) in patients with intermediary-high risk pulmonary embolism (PE).
- Trial name
- BETULA (NCT03854266)
- Testing
- Low dose alteplase, Unfractionated heparin, Infusion catheter
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- University of Aarhus
Vitamin D Deficiency, Pre-Eclampsia
Vitamin D in Pregnancy
Danish pregnant women are recommended ad daily vitamin D supplement of 10 µg. Despite the fact that 9 out of 10 women take vitamin D supplements, more than 40% of pregnant women are vitamin D deficient, putting them at an…
- Conditions
- Vitamin D Deficiency, Pre-Eclampsia, Fetal Growth Retardation, Gestational Diabetes
- Trial name
- GRAVITD (NCT04291313)
- Testing
- Vitamin D3 (90µg), Vitamin D3 (10µg)
- Where
- 2 sites in Denmark
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Stroke
Predictors for Prehospital Delay in Stroke Treatment
Stroke is the second-leading cause of death worldwide and a leading cause of long-term disability. Annually 12,000 people in Denmark suffers a stroke; half of them will have long-term disabilities that may affect the activities…
- Trial name
- NCT03759691
- Testing
- Structured interview
- Where
- 2 sites in Denmark
- Volunteers
- 650 people
- Sponsor
- University of Aarhus
Gestational Diabetes
The Acute Effect of Physical Activity on Postprandial Blood Glucose in Pregnant Women
The aim of the project is to investigate the acute effect of exercise on blood glucose after food consumption. Thereby the investigators wish to achieve knowledge that can improve prevention and treatment of gestational…
- Trial name
- NCT03641170
- Testing
- Physical activity, Inactivity, Fixed diet.
- Where
- Denmark
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Coxa Saltans External
Resistance Training for Patients Diagnosed With External Snapping Hip
The purpose of this study is to investigate whether targeted progressive resistance training is safe and feasible for patients with external snapping hip. Dropout rates, adverse events and training adherence are investigated.
- Trial name
- NCT03703362
- Testing
- Resistance training
- Where
- 3 sites in Denmark
- Volunteers
- 9 people
- Sponsor
- University of Aarhus
Hip Dysplasia
Soft Tissue Pathology in Hip Dysplasia Before and After Periacetabular Osteotomy
Introduction: The lack of congruence between the acetabulum and femoral head in hip dysplasia compromise the passive stability of the hip joint resulting in increased stress on the acetabular labrum, joint capsule and the muscles…
- Trial name
- NCT02311166
- Where
- 2 sites in Denmark
- Volunteers
- 100 people
- Sponsor
- University of Aarhus
Healthy
Renal Functional Magnetic Resonance Imaging in Healthy Persons - Reproducibility and Impact of Stress
The main purpose of the study is to describe the applicability and reproducibility of functional MRI scans of the kidneys in healthy participants.
- Trial name
- NCT04656314
- Testing
- Functional MRI scan
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Mental Disorder
Psychiatric Inpatient Discharge Data - Rwanda
The aim is to provide a comprehensive assessment regarding the service provision and the accessibility to intensive mental health care in Rwanda
- Trial name
- NCT04648982
- Testing
- Admission to inpatient psychiatric unit
- Where
- 2 sites in Rwanda
- Volunteers
- 1,000 people
- Sponsor
- University of Aarhus
Perianal Fistula, Adipose Tissue
Adipose Derived Mesenchymal Stem Cell Characteristics in Anal Fistulas
This study investigated the cellular and molecular characteristics of AT-MSCs obtained from autologous AT therapy in patients with high transphincteric perianal fistulas of crytoglandular origin.
- Conditions
- Perianal Fistula, Adipose Tissue, Tissue Transplantation
- Trial name
- NCT04834609
- Testing
- Injection of autologous adipose tissue in anal fistula
- Volunteers
- 27 people
- Sponsor
- University of Aarhus
Esophageal Cancer
Dose Escalated Adaptive RadioTherapy in Definitive Chemo-radiotherapy for Esophageal Cancer
In Denmark, 1000 new cases of esophageal and gastro-esophageal junction cancer occur every year. Surgery is the primary treatment for patients with localized disease who are considered medically and technically operable.
- Trial name
- DART (NCT04086901)
- Testing
- Radiotherapy dose escalation
- Where
- 3 sites in Denmark
- Volunteers
- 3 people
- Sponsor
- University of Aarhus
Stroke, Upper Limb Hypertonia
An Algorithm for Prognosis of Upper Limb Paresis in Patients With Subacute Stroke
Aim study 1:Assess the accuracy of PREP2 when applied in a subacute rehabilitation setting. Aim study 2: Prediction of real life UL use. Method: A prospective cohort study.
- Conditions
- Stroke, Upper Limb Hypertonia, Physical Activity
- Trial name
- NCT03632499
- Testing
- rehabilitation
- Where
- Denmark
- Volunteers
- 103 people
- Sponsor
- University of Aarhus
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