Clinical trials: sponsored by University of Aarhus
Organic, Including Symptomatic, Mental Disorders, Substance Use
Exploring the Comorbidity Between Mental Disorders and General Medical Conditions
Mental disorders have been shown to be associated with a number of general medical conditions (also referred to as somatic or physical conditions).
- Conditions
- Organic, Including Symptomatic, Mental Disorders, Substance Use, Schizophrenia, Mood [Affective] Disorders
- Trial name
- COMO-GMC (NCT03847753)
- Testing
- Organic Disorders, Substance Use Disorders, Schizophrenia Disorders
- Volunteers
- 5,940,299 people
- Sponsor
- University of Aarhus
Univentricular Heart, Lymphatic Abnormalities
Lymphatic Function in Patients With a Fontan Circulation From Brazil
It is suggested that the elevated central venous pressure in patients with a Fontan circulation can provoke manifestation of lymphatic dysfunction, met as plastic bronchitis, peripheral oedema and most feared protein-losing…
- Conditions
- Univentricular Heart, Lymphatic Abnormalities, Lymphatic Edema
- Trial name
- NCT04394507
- Testing
- Near-Infrared Fluorescence imaging, Strain Gauge Plethysmography
- Where
- 2 sites in Denmark
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Performance, Nutrition
Nutrient Supplementation Influences Mitochondria Adaptation
Twenty-four well trained runners (VO2max 60.73.7 ml O2 Kg-1 min1) completed a six week block randomized controlled intervention period.
- Conditions
- Performance, Nutrition, Protein
- Trial name
- NCT03561337
- Testing
- PROTEIN-CARBOHYDRATE, CARBOHDYRATE
- Where
- 2 sites in Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Heart Failure, Ischemia Reperfusion Injury
Functional and Metabolic Effects of Ketone Bodies on Human Atrial Tissue in Patients With and Without Heart Failure
This proof of concept study aims to evaluate the effects of applying ketone bodies to human atrial tissue biopsies using an atrial strips model and high resolution respirometry.
- Conditions
- Heart Failure, Ischemia Reperfusion Injury, Mitochondrial Pathology
- Trial name
- NCT04379934
- Testing
- 3-hydroxybuturate
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- University of Aarhus
Terminal Illness
Is Acupuncture Able to Reduce Nausea and Vomiting in the Terminal Ill Patient
A comparative effectiveness research design was used. The sample size was calculated to 136 patients, who were randomized to an intervention group and a control group respectively.
- Trial name
- NCT04378998
- Testing
- Acupuncture
- Volunteers
- 136 people
- Sponsor
- University of Aarhus
Frail Elderly Syndrome
Telerehabilitation in Geriatric Patients at Aarhus University Hospital, Denmark
Background Older patients admitted to an Emergency Department (ED) are dependent on assistive devices and almost 16 % have no gait function.
- Trial name
- NCT03952858
- Testing
- Telerehabilitation Group
- Where
- 2 sites in Denmark
- Sponsor
- University of Aarhus
Renal Neoplasm With Metastasis, Response Evaluation Criteria in Solid Tumors
Improved Assessment of Response in Metastatic Renal Cell Carcinoma Using Spectral-CT
The incidence of renal cancer in Denmark is approximately 900 new cases per year. Untreated, the 5-year survival rate for metastatic renal cancer (mRCC) is 2%.
- Trial name
- NCT03616951
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- University of Aarhus
X-rays; Effects, Health Impairment
Evaluation of Mobile X-ray Within the Triple Aim Method
Background: In foreign countries, mobile x-ray already is being used where transfer to the radiology department at the hospital may be an obstacle.
- Conditions
- X-rays; Effects, Health Impairment, Patient Satisfaction
- Trial name
- NCT04005040
- Testing
- Mobile X-ray
- Where
- Denmark
- Volunteers
- 374 people
- Sponsor
- University of Aarhus
Tooth-loss
The Use of Platelet-rich Fibrin (PRF) Membranes in Lateral Alveolar Ridge Augmentation When Jaw Bone is Missing Before Dental Implant Installation. A Study Comparing an Autogenous Bone Block Graft Covered Either by a (PRF) Membrane (Test) or Bone Substitute and a Barrier Membrane (Control)
Tooth loss can in many cases be treated with an artificial titanium root (dental implant) and subsequent manufacture of a porcelain crown.
- Trial name
- NCT04350749
- Testing
- PRF is added in the test group.
- Where
- Denmark
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Cancer, Primary Health Care
A Feasibility Study of Direct Access to an Abdominal ´Yes-No´ Pathway for Primary Care Patients
Background To optimise cancer outcome in Denmark, cancer diagnostic pathways should, beside cancer patient pathways (CPP) for alarm symptoms, also include a pathway for patients with vague and non-specific symptoms.
- Trial name
- NCT03878940
- Testing
- Abdominal ´yes-no´ pathway
- Where
- Denmark
- Volunteers
- 27 people
- Sponsor
- University of Aarhus
Ligament Injury, Wrist Sprain
Danish Multicenter Scapholunate Ligament Study
Comparison of two surgical techniques commonly used for reconstruction of the scapholunate (SL) ligament. A randomized multicenter study.
- Trial name
- NCT04348253
- Testing
- Berger, 3LT
- Where
- 2 sites in Denmark
- Volunteers
- 100 people
- Sponsor
- University of Aarhus
Hepatitis C
Macrophage Activation Markers During Sofosbuvir-based Treatment Regimes of Chronic Hepatitis C
The purpose of the study is to investigate how the liver is affected with regard to inflammation and fibrosis during Sofosbuvir based treatment regimes of chronic hepatitis C.
- Trial name
- NCT02528461
- Testing
- Galactose, Gastroscopy, Liver biopsy
- Where
- Denmark
- Volunteers
- 71 people
- Sponsor
- University of Aarhus
Colitis, Ulcerative, Inflammatory Bowel Diseases
CAsein GLycomacropeptide in Ulcerative Colitis - Anti-Inflammatory and Microbiome Modulating Effects (CAGLUCIM)
Casein glycomacropeptide (CGMP) has anti-inflammatory properties in experimental rodent colitis and using human in vitro inflammation models. Its use as a food ingredient has proven safe and with no influence on dietary intake.
- Trial name
- CAGLUCIM (NCT02825914)
- Testing
- Casein glycomacropeptide (CGMP)
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- University of Aarhus
Intravenous Catheters
The Clinical Efficacy of Midline Catheters
The study will evaluate the clinical efficacy of midline catheters compared to conventional treatment in patients with an expected intravenous therapy duration of more than 5 days. Patients will be randomized in a 1:1 ratio.
- Trial name
- NCT03457259
- Testing
- PVC and/or PICCline, Midline
- Where
- Denmark
- Volunteers
- 120 people
- Sponsor
- University of Aarhus
Myasthenia Gravis
Beta-agonist Efficacy and Tolerability as Adjuvant Therapy in Myasthenia Gravis
This study examines the effect of adjuvant therapy with the oral beta-agonist Salbutamol in patients with generalized myasthenia gravis on stable standard of care having residual symptoms.
- Trial name
- BETA-MG (NCT03914638)
- Testing
- Salbutamol 4Mg Tablet
- Where
- 2 sites in Denmark
- Volunteers
- 30 people
- Sponsor
- University of Aarhus
Ovarian Cancer
A Trial of Fast Access to Transvaginal Ultrasound Through General Practice for Earlier Diagnosis of Ovarian Cancer
Background Ovarian cancer (OC) is a disease with a poor prognosis due to diagnosis at late stage. Early-stage OC presents with non-specific and vague symptoms and therefore OC usually is not detected until reaching an advanced…
- Trial name
- NCT03069872
- Testing
- Transvaginal ultrasound
- Where
- Denmark
- Volunteers
- 490 people
- Sponsor
- University of Aarhus
Bereavement, Grief
Bereavement Management - Description, Assessment and Care
This study aims to develop a risk assessment tool to identify bereaved in risk of complicated grief reactions and to implement a bereavement management programme in primary health care based on the Dual Process Model of coping…
- Trial name
- NCT01292512
- Testing
- Prognostic screening for complicated grief
- Where
- Denmark
- Volunteers
- 402 people
- Sponsor
- University of Aarhus
Hypopituitarism, Insulin Resistance
Lipolytic Effects of GH in Hypopituitary Patients in Vivo
Growth hormone (GH) is essential for longitudinal bone growth and somatic development. These protein anabolic effects require sufficient nutritional supply.
- Conditions
- Hypopituitarism, Insulin Resistance, Endocrine System Diseases, Glucose Metabolism Disorders
- Trial name
- NCT02782208
- Testing
- Acipimox, GH substitution, GH pause
- Where
- Denmark
- Volunteers
- 9 people
- Sponsor
- University of Aarhus
Metabolic Diseases, Growth Hormone Treatment
Lipolytic Effects of GH in Human Subjects in Vivo
Growth hormone (GH) induces fat metabolism. The mechanisms underlying the fat metabolizing effects of GH remain elusive. However, it is known that insulin suppresses fat metabolism, and GH inhibits the expression of certain…
- Trial name
- NCT02782221
- Testing
- Growth Hormone, Pegisomant
- Where
- Denmark
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Psychological Distress
Compassion Cultivation Training (CCT): An Intervention for Caregivers
This study will begin a novel line of research on CCT in Denmark as a preventive intervention for caregivers of people suffering from a mental illness.
- Trial name
- NCT03730155
- Testing
- CCT intervention.
- Where
- 2 sites in Denmark
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
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