Clinical trials: sponsored by University of Aarhus
Overweight and Obesity
The Effects of Combined Energy and Carbohydrate Restriction on Exercise Capacity
The effect of calorie restriction combined with low or moderate carbohydrate availability on exercise capacity, metabolism and metabolic health indicators will be measured in a randomized parallel group design.
- Trial name
- CHO-EX (NCT06381908)
- Testing
- Calorie-restriction with low carbohydrate, Calorie-restriction with moderate carbohydrate
- Where
- Denmark
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Lung Cancer, Radiation-Induced Disorder
Functional Lung Avoidance SPECT-guided Radiation Therapy of Lung Cancer
Study aims to determine if functional lung avoidance based on perfusion single photon emission (SPECT)/CT scan, improves toxicity outcomes for patients with advanced lung cancer undergoing chemo-radiotherapy.
- Conditions
- Lung Cancer, Radiation-Induced Disorder, Radiation Pneumonitis, Pulmonary Disease
- Trial name
- ASPECT (NCT04676828)
- Testing
- Single-photon-emission CT scan
- Where
- 2 sites in Australia, Denmark
- Volunteers
- 90 people
- Sponsor
- University of Aarhus
Neonatal Care, Burnout, Professional
Developing Competency Awareness and Clinical Coordination in a Neonatal Unit
In neonatal care, patient safety depends not only on individual clinical skills, but also on how teams recognize and use the competencies available during a shift.
- Conditions
- Neonatal Care, Burnout, Professional, Psychological Safety, Interprofessional Relations
- Trial name
- NeoSim (NCT07423468)
- Testing
- Competency Awareness and Simulation-Based Intervention
- Where
- Denmark
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Hip Osteoarthritis
Effects of EDUcation and EXercise Compared to Education Alone on Clinical and Physiological Outcomes in Patients With Hip Osteoarthritis
The EDUEX trial will determine whether the addition of progressive resistance training (PRT) to a patient education program (EDU) will improve clinical outcomes in patients with hip OA.
- Trial name
- EDUEX (NCT06391554)
- Testing
- PRT, EDU
- Where
- 2 sites in Denmark
- Volunteers
- 150 people
- Sponsor
- University of Aarhus
Lower Limb Amputation Above Knee
Microenvironment in Patients Undergoing Non-traumatic Amputation
The microenvironment of the amputation stump in patients undergoing non-traumatic transfemoral amputation will be investigated with a combination of microdialysis and tissue sampling.
- Trial name
- MiAMII (NCT07384689)
- Testing
- ciNPWT, SSD
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- University of Aarhus
Cervical Dysplasia, Cervical Disease
iMproving thE DIagnostics And Treatment Of ceRvical Precancer
Cervical cancer screening is important as it enables identification of women at increased risk of the disease, but high-quality diagnostics of screen-positive women and effective treatment of those with precancer are critical in…
- Conditions
- Cervical Dysplasia, Cervical Disease, Cervical Lesion, Cervical Cancer
- Trial name
- MEDIATOR (NCT05870787)
- Testing
- Swede score colposcopy
- Where
- 7 sites in Denmark
- Volunteers
- 929 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Colonic Diverticulitis, Colorectal Cancer
The Diverticulitis Study
Acute colonic diverticulitis is when a part of the colon gets swollen and inflamed. The diagnosis is based on a CT scan, which can show thickening of the colonic walls and infiltration of the diverticula.
- Conditions
- Colonic Diverticulitis, Colorectal Cancer, Acute Diverticulitis
- Trial name
- NCT06023004
- Where
- 5 sites in Denmark
- Volunteers
- 250 people
- Sponsor
- University of Aarhus
Colorectal Neoplasms, Colorectal Cancer
DANISH.MRD: Danish Assessment of Minimal Residual Disease by Liquid Biopsies
Approximately two-thirds of all colorectal cancer patients undergo surgery with the aim of curing them. However, despite the surgery, 20-25% of them experience relapse.
- Conditions
- Colorectal Neoplasms, Colorectal Cancer, Colorectal Adenocarcinoma, Colorectal Cancer Stage I
- Trial name
- NCT06076811
- Where
- 10 sites in Denmark
- Volunteers
- 1,600 people
- Sponsor
- University of Aarhus
Metabolic Associated Fatty Liver Disease, Type 2 Diabetes (T2DM)
Glucagon Resistance in Patients With MASLD and T2DM
The goal of this clinical trial is to investigate the sensitivity to glucagon in patients with type 2 diabetes mellitus (T2DM), with and without metabolic associated fatty liver disease (MASLD).
- Trial name
- NCT07246421
- Testing
- Glugagon
- Where
- Denmark
- Volunteers
- 24 people
- Sponsor
- University of Aarhus
Type 1 Diabetes Mellitus
The MICRON Study - A Steno 1 Substudy
The goal of this observational study is to compare cardiac and renal oxygen consumption among subjects with type 1 diabetes treated with either multifactorial intervention or according to the current standard care.
- Trial name
- MICRON (NCT07270172)
- Where
- 5 sites in Denmark
- Volunteers
- 40 people
- Sponsor
- University of Aarhus
Endometrial Cancer
The Clinical Utility of DNA Methylation Testing in Patient-collected Urine and Vaginal Samples to Detect Endometrial Cancer: a Case-control Study
The goal of this observational case-control study is to investigate the use of DNA-methylation testing in patient-collected urine and vaginal samples to detect endometrial cancer.
- Trial name
- NCT06846775
- Testing
- DNA-methylation testing in patient-collected urine and vaginal samples
- Where
- 3 sites in Denmark
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Revision Total Hip Arthroplasty
Exercise Intervention Targeting Hip Strengthening Compared to Usual Care in Patients Undergoing Revision Hip Replacement
There is sparse evidence on revision total hip replacement (THR), regarding the effectiveness on pain and function, and no consensus exists on optimal rehabilitation after revision THR.
- Trial name
- StrongHip (NCT05657054)
- Testing
- Exercise Intervention Targeting Hip Strengthening, Usual Care
- Where
- 9 sites in Denmark
- Volunteers
- 84 people
- Sponsor
- University of Aarhus
Insulin Resistance, Obesity & Overweight
Effects of Ketone Bodies on Insulin Sensitivity
KETO-SENSE is a clinical research study investigating how ketone bodies affect energy metabolism and insulin sensitivity in humans.
- Conditions
- Insulin Resistance, Obesity & Overweight, Energy Metabolism, Ketone Body Metabolism
- Trial name
- KETO-SENSE (NCT07359625)
- Testing
- Growth Hormone, Human, Oral ketone supplement (KetoAid®, KE4)
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Medical Education, Pediatrics
Using Simulation to Support Staff and Improve Quality of Treatment: An Intervention Project Within Pediatrics
Background: Effective teamwork and quality care are crucial for patient safety overall. Simulation-based team training offers a valuable approach to improving communication, coordination, and decision-making among healthcare…
- Conditions
- Medical Education, Pediatrics, Patient Outcomes
- Trial name
- PAEDSIM (NCT06064045)
- Testing
- Simulation-based team training intervention
- Where
- Denmark
- Volunteers
- 1,238 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Circadian Rhythms, Time Perception
The Effect of a Continuous 1-Hour Time Delay on Circadian Rhythms
The purpose of this study is to investigate whether the experience of a daily time delay can affect our internal circadian rhythm.
- Conditions
- Circadian Rhythms, Time Perception, Sleep
- Trial name
- NCT07317349
- Testing
- Fixed daily routine, Daily time delay
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Non-Melanoma Skin Cancer (NMSC), Basal Cell Carcinoma of Skin
The Role of Radiotherapy for the Management of Non-melanoma Skin Cancer in Denmark.
The goal of this observational study is to learn about the long-term effects of radiotherapy for people who were treated for non-melanoma skin cancer (NMSC) in the head and neck area.
- Conditions
- Non-Melanoma Skin Cancer (NMSC), Basal Cell Carcinoma of Skin, Squamous Cell Carcinoma of the Skin
- Trial name
- DOSCA-2 (NCT07347392)
- Testing
- Follow-up visit at least two years after treatment
- Where
- Denmark
- Volunteers
- 2,900 people
- Sponsor
- University of Aarhus
Multiple Sclerosis, Chronic Pain
EXpain Trial - Exercise an a Non-pharmacological Pain-relieving Treatment in People With Multiple Sclerosis
The primary goal of this study is to test whether 12 weeks of progressive resistance exercise is an effective non-pharmacological treatment for reducing pain in people with multiple sclerosis and chronic pain.
- Conditions
- Multiple Sclerosis, Chronic Pain, Neuropathic Pain
- Trial name
- EXpain (NCT07342777)
- Testing
- Progressive resistance exercise, Usual Care followed by progressive resistance exercise
- Where
- Denmark
- Volunteers
- 116 people
- Sponsor
- University of Aarhus
ADHD - Attention Deficit Disorder With Hyperactivity, Attention Concentration Difficulty
Danish Access to Support and Help (DASH): Increasing Access to an Evidence-based Intervention for Children With ADHD and Their Parents
The aim of this study is to devise implementation strategies for the New Forest Parenting Programme (NFPP) to support a community implementation model (NFPP-CIM) and test its feasibility and acceptability for parents and…
- Trial name
- DASH (NCT07339696)
- Testing
- New Forest Parenting Programme
- Where
- Denmark
- Volunteers
- 90 people
- Sponsor
- University of Aarhus
Colitis Ulcerosa, Colitis Ulcerative
Magnesium in Gastrointestinal Disease
Individuals with gastrointestinal diseases - such as Crohn's disease, ulcerative colitis, ileostomy, or bile acid diarrhoea - are at increased risk of magnesium deficiency.
- Conditions
- Colitis Ulcerosa, Colitis Ulcerative, Crohns Disease, Morbus Crohn
- Trial name
- MAGIC (NCT07338565)
- Where
- Denmark
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Sex Chromosome Disorders
Clinical and Genetic Aspects in Fetuses and Children With Sex Chromosome Disorders
The aim of the project is to: 1. Investigate organ development and growth in fetuses with sex chromosome disorders; 2. Investigate growth, development, and morbidity in children with sex chromosome disorders during the first…
- Trial name
- NCT07341412
- Where
- Denmark
- Volunteers
- 300 people
- Sponsor
- University of Aarhus
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