Clinical trials: sponsored by University of Alberta
SARS-CoV-2 Infection, Covid19
Over-the-counter Medications & COVID-19
Ibuprofen is one of several common medications implicated in coronavirus disease 2019 (COVID-19) severity. On March 11, the Lancet Respiratory Medicine published a letter stating ibuprofen can increase angiotensin-converting…
- Trial name
- OTC℞&COVID19 (NCT04500639)
- Where
- Canada
- Volunteers
- 461 people
- Sponsor
- University of Alberta
Cancer, Breast
Time-restricted Eating in Survivors Trial
Breast cancer survivors aged 60+ and with overweight/obesity who had completed chemotherapy 1-6 years earlier completed 8 weeks of 12-8 pm weekday-only time-restricted eating.
- Trial name
- TEST (NCT05639829)
- Testing
- Time-restricted eating
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- University of Alberta
Nerve Injury, Surgery
AIN Transfer for Cubital Tunnel Syndrome
Ulnar nerve compressive injury due to cubital tunnel syndrome is very common. Because of the long distance to the target muscles in the hand, functional outcome in severe cases even with decompression surgery is often poor.
- Trial name
- NCT05242302
- Testing
- nerve transfer
- Where
- Canada
- Volunteers
- 65 people
- Sponsor
- University of Alberta
Colorectal Cancer
Protein Recommendation to Increase Muscle
This is a feasibility study to test the potential efficacy of diets of different amounts of protein and calories for patients with cancer.
- Trial name
- PRIMe (NCT02788955)
- Testing
- Dietary counselling, Dietary Protein
- Where
- 2 sites in Canada
- Volunteers
- 50 people
- Sponsor
- University of Alberta
Dementia, Family
Feasibility Study of "My Tools 4 Care-In Care" for Family Caregivers of Residential-Living Older Persons With Dementia
Following institutionalization of a relative with Alzheimer's disease and related dementia (ADRD), family carers continue to provide care and must learn to negotiate with staff, and navigate the system, all of which can affect…
- Trial name
- NCT03571165
- Testing
- My Tools 4 Care - In Care
- Where
- Canada
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Type 1 Diabetes
Effectiveness of Aerobic Exercise to Mitigate Hyperglycemia After Fasted Resistance Exercise
Certain types and timings of exercise are known to cause hyperglycemia (high blood glucose) in people with type 1 diabetes. Hyperglycemia increases the risk of most long-term complications for individuals with this complication.
- Trial name
- NCT05203653
- Testing
- Resistance exercise only, Resistance exercise plus cool down
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- University of Alberta
Type II Myocardial Infarction
Rivaroxaban in Type 2 Myocardial Infarctions
This trial is the pilot phase of a randomized controlled trial to test the feasibility of recruiting patients with a type 2 myocardial infarction and randomizing them to low-dose rivaroxaban to reduce the risk of major…
- Trial name
- R2MI (NCT04838808)
- Testing
- Rivaroxaban 2.5 MG [Xarelto]
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- University of Alberta
Low Back Pain
Effect of Lumbar Bracing on Spinal Function
A recent province-wide survey (Alberta, Canada) suggests that clinicians' beliefs about soft lumbar bracing for low back pain (LBP) vary substantially.
- Trial name
- NCT02251106
- Testing
- Lumbar corset (Quickdraw, Aspen Medical Products)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Myasthenia Gravis
A Pilot Trial To Assess The Feasibility And Efficacy Of SCIG In Patients With MG Exacerbation (SCIG-MG)
This is a prospective open-label, uncontrolled, single-blind, pilot clinical trial. The primary objective is to assess the efficacy, safety, feasibility and tolerability of SCIG in patients with worsening MG.
- Trial name
- SCIG-MG (NCT02774239)
- Testing
- Human normal immunoglobulin G (IgG)
- Where
- 2 sites in Canada
- Volunteers
- 26 people
- Sponsor
- University of Alberta
Diabetes, Type 1
Edmonton Automated Sugar Intelligence - Intelligent Diabetes Management, EASI-IDM, App Program to Assist Diabetes Care
A closed loop system for diabetes care utilizing an insulin pump, continuous glucose sensing and appropriate mathematical modelling to guide insulin dosing is a goal for those with Type 1 diabetes.
- Trial name
- EASI-IDM (NCT02214719)
- Testing
- EASI-IDM use
- Where
- Canada
- Volunteers
- 31 people
- Sponsor
- University of Alberta
Dementia, Family
Supporting Family Caregivers of Persons Living With Dementia: Effectiveness and Sustainability of MT4C-In Care
When a person living with dementia moves into a long term care facility, their family members remain involved in their care. They learn new roles and make significant and often stressful adjustments.
- Trial name
- NCT04226872
- Testing
- My Tools for Care - In Care
- Where
- 4 sites in Canada
- Volunteers
- 234 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Cirrhosis, Liver, Hepatic Encephalopathy
Feasibility of an App-based Nutrition & Exercise Program in Cirrhosis
The personalized nutrition and exercise app was designed for use by individuals living with chronic conditions. The pilot study examines the acceptance and use of the online, interactive program to support self-management in…
- Trial name
- NCT05033327
- Testing
- Nutrition and Exercise app
- Where
- Canada
- Volunteers
- 27 people
- Sponsor
- University of Alberta
Heart Failure
SODIUM-HF: Study of Dietary Intervention Under 100 MMOL in Heart Failure
SODIUM-HF is a multicenter clinical trial in ambulatory patients with chronic HF to evaluate the efficacy of a low sodium containing diet on a composite clinical outcome composed of of all-cause mortality, cardiovascular…
- Trial name
- SODIUM-HF (NCT02012179)
- Testing
- Low sodium diet
- Where
- 26 sites in Australia, Canada and 3 more
- Volunteers
- 806 people
- Sponsor
- University of Alberta
Covid19, Coronavirus Infection
MOIST Study: Multi-Organ Imaging With Serial Testing in COVID-19 Infected Patients
While many people with COVID-19 suffer from respiratory disease, there is growing evidence that the virus also affects other organs.
- Conditions
- Covid19, Coronavirus Infection, SARS-CoV Infection
- Trial name
- MOIST (NCT04525404)
- Testing
- MRI (heart, brain, lungs, liver), Bloodwork, Cognitive testing
- Where
- 2 sites in Canada
- Volunteers
- 215 people
- Sponsor
- University of Alberta
Pregnancy Related, Glucose, Low Blood
Interval Versus Continuous Exercise During Pregnancy
The objective of this randomized cross-over design was to investigate the fetal well-being and maternal glycemic response to an acute bout of aerobic high-intensity interval training (HIIT) and moderate-intensity continuous…
- Conditions
- Pregnancy Related, Glucose, Low Blood, Fetal Heart Rate or Rhythm Abnormality Affecting Fetus, Fetal Blood Flow
- Trial name
- NCT05369247
- Testing
- High intensity Interval Training, Moderate Intensity Continuous Training
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Epistaxis
Management of Persistent Epistaxis Using Floseal Hemostatic Matrix
Nosebleeds that persist even after adequate traditional nasal packing may require aggressive treatment strategies to stop bleeding.
- Trial name
- NCT02488135
- Testing
- Floseal Hemostatic Matrix, Traditional Nasal Packing
- Where
- Canada
- Volunteers
- 26 people
- Sponsor
- University of Alberta
Prematurity
Effect of Monitoring Devices on Healthcare Provider Performance During Neonatal Resuscitation
Babies born very early (at less than 32 weeks) usually need help to breath right at birth, also called neonatal resuscitation. Healthcare providers (HCPs) are specially trained to provide this help.
- Trial name
- NCT04521725
- Testing
- Respiratory Function Monitor (RFM), Cerebral Near-Infrared Spectroscopy (NIRS)
- Where
- Canada
- Volunteers
- 51 people
- Sponsor
- University of Alberta
Nasal Obstruction
Comparison of a Septal Stapler to Suture Closure in Nasal Septoplasty
The primary objective of this study is to determine if there is a time savings in the operating room by using a septal stapler instead of suture in closure of primary septoplasty.
- Trial name
- NCT01541839
- Testing
- Septal Stapler
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- University of Alberta
Hypertension
Improving Hypertension Detection and Control Through a Hypertension Certification Program Based Upon the Hypertension Canada Guidelines
This study will assess the impact of a hypertension management certification program for community pharmacists on the blood pressure control of patients managed by the pharmacists enrolled.
- Trial name
- NCT03965104
- Testing
- Hypertension Canada Professional Certification Program: HC-PCP
- Where
- Canada
- Volunteers
- 890 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Chronic Diseases
A Cluster-randomized Controlled Knowledge Translation Feasibility Study in Alberta Community Pharmacies
Background: Despite evidence of benefit for pharmacist involvement in chronic disease management, the provision of these services in community pharmacy has been suboptimal.
- Trial name
- NCT02191111
- Testing
- Task-focused facilitation
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Alberta