Clinical trials: sponsored by University of Alberta
Benign Prostatic Hyperplasia
On Label, Randomized, Double-Blind, Placebo-Controlled Trial of Preoperative Finasteride in Patients Undergoing Transurethral Resection of the Prostate (TURP)
Transurethral resection of the prostate (TURP) is a common treatment for benign prostatic hyperplasia (BPH). A common complication of TURP is blood loss.
- Trial name
- NCT00564460
- Testing
- Finasteride
- Where
- Canada
- Sponsor
- University of Alberta
Diabetes, Chronic Kidney Disease
The Alberta Vascular Risk Reduction Community Pharmacy Project: RxEACH
Cardiovascular disease (disease of the heart and blood vessels) is one of the leading causes of death in Canada. It also carries a financial burden on the Canadian economy with a yearly cost close to $21 billion divided between…
- Conditions
- Diabetes, Chronic Kidney Disease, Established Atherosclerotic Vascular Disease, Framingham Risk Score More Than 20 Percent
- Trial name
- RxEACH (NCT01979471)
- Testing
- Advanced Care
- Where
- Canada
- Volunteers
- 723 people
- Sponsor
- University of Alberta
Carpal Tunnel Syndrome, Compression Neuropathy
Acetyl-l-carnitine to Enhance Nerve Regeneration in Carpal Tunnel Syndrome
Study Hypothesis: Acetyl-l-carnitine increases nerve regeneration in patients with severe carpal tunnel syndrome. Carpal tunnel syndrome (CTS) is common, affecting almost 3% of the general population.
- Trial name
- NCT02141035
- Testing
- Acetyl-l-carnitine
- Where
- 3 sites in Canada
- Volunteers
- 20 people
- Sponsor
- University of Alberta
Stroke, Acute
Perfusion and Antihypertensive Therapy in Acute Ischemic Stroke
The purpose of this study is to provide a description of blood flow changes in the brain after blood pressure lowering drugs are given.
- Trial name
- PATIS (NCT02327793)
- Testing
- Nitroglycerin, Labetalol
- Where
- Canada
- Volunteers
- 65 people
- Sponsor
- University of Alberta
Anticoagulation
Evaluation of Maintenance Dosing vs Loading Dosing Upon Restarting Warfarin Therapy: A Prospective Randomized Trial
A prospective, randomized trial to compare the time taken to achieve a therapeutic INR upon re-starting warfarin at a "loading" dose (namely 1.5 times the "maintenance" dose for 3 days) compared to the known "maintenance" dose.
- Trial name
- NCT01124058
- Testing
- warfarin
- Where
- Canada
- Volunteers
- 39 people
- Sponsor
- University of Alberta
Acute Pancreatitis
Timing of Indomethacin Administration for the Prevention of Post-ERCP Pancreatitis (PEP)
To determine if the timing of administration of indomethacin affects the primary outcome of post-ERCP pancreatitis (PEP). Patients undergoing ERCP will be randomly assigned to receive pre or post-procedure rectal indomethacin to…
- Trial name
- NCT02111707
- Testing
- Rectal indomethacin 100mg one time before or after ERCP
- Where
- Canada
- Volunteers
- 534 people
- Sponsor
- University of Alberta
Adverse Events
Comparison of Active vs. Passive Surveillance to Collect Adverse Events
This cluster randomized trial will be the first to specifically evaluate passive versus active surveillance methods collection of adverse events (AEs).
- Trial name
- NCT02268331
- Testing
- Active Surveillance, Passive Surveillance
- Where
- Canada
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Morbid Obesity
Gastric Procedures for Obesity
This is a prospective case series study; all morbidly obese patients that need surgical management in Royal Alexandra Hospital will be provided 3 surgical options: Laparoscopic Sleeve Gastrectomy (LSG), laparoscopic Roux-en-Y…
- Trial name
- NCT01026181
- Volunteers
- 150 people
- Sponsor
- University of Alberta
Leukemia, Lymphoma
Using Telephone Counselling to Improve Exercise Participation in Hematologic Cancer Survivors
This study evaluates the impact of a 12-week theory-based exercise telephone counselling program (versus a self-directed exercise group) on closing the exercise intention-behavior gap in a sample of hematologic cancer survivors.
- Conditions
- Leukemia, Lymphoma, Lymphoma, Non-Hodgkin, Behavior, Health
- Trial name
- NCT03052777
- Testing
- Telephone counselling
- Where
- Canada
- Volunteers
- 51 people
- Sponsor
- University of Alberta
Morbid Obesity
Outcomes of the Adjustable Gastric Band in a Publicly Funded Obesity Program
The majority of data documenting the outcomes for the adjustable gastric band (LAGB) originate from non-publicly funded surgical centres.
- Trial name
- NCT01149512
- Where
- Canada
- Volunteers
- 178 people
- Sponsor
- University of Alberta
Schizophrenia
L-arginine in Treatment as Usual in Schizophrenia
STUDY OBJECTIVES: To determine whether the addition of L-arginine to treatment as usual (TAU) in schizophrenia further improves and enhances therapeutic efficacy (positive, negative and depressive symptoms) and effectiveness of…
- Trial name
- NCT00718510
- Testing
- L-Arginine
- Where
- Canada
- Volunteers
- 13 people
- Sponsor
- University of Alberta
Small-Fiber Neuropathy
Evaluation of Pregabalin in Idiopathic Small Fiber Neuropathy
Idiopathic Small Fiber Neuropathy (called SFN for short), is a condition where nerves that sense pain have become damaged, and often painful.
- Trial name
- NCT00787462
- Testing
- Pregabalin
- Where
- Canada
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Type 2 Diabetes
Pilot Test of a Chinese Menu Plan for Type 2 Diabetes
In Canada, there is a fast-growing population with diabetes, and the majority of diabetes cases are type 2 diabetes (T2D). Diabetes and its complications, such as cardiovascular diseases, eye disease and foot disease, impair the…
- Trial name
- NCT02327429
- Testing
- A Chinese menu plan for type 2 diabetes
- Volunteers
- 19 people
- Sponsor
- University of Alberta
Congenital Heart Defects
Congenital Heart Adolescents: Program of Transition Evaluation Research
The objective of this study is to evaluate the potential role of a cardiology clinic-based educational intervention for 15 to 17 year olds with congenital heart disease (CHD) and their parents, and to determine whether this…
- Trial name
- CHAPTER (NCT01286480)
- Testing
- Clinic-based Educational Intervention
- Where
- Canada
- Volunteers
- 66 people
- Sponsor
- University of Alberta
Family, Dementia
Evaluation of "My Tools 4 Care" for Family Caregivers of Persons With Dementia
With the number of Canadians with Alzheimer's disease and related dementias (ADRD) growing, supporting family care partners of persons with ADRD is critical.
- Trial name
- NCT02428387
- Testing
- My Tools 4 Care
- Where
- 2 sites in Canada
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Myocardial Infarction
Which Therapy for Acute Heart Attacks? (The WEST Study)
In the setting of acute myocardial infarction (heart attacks), the principle objective of the WEST Study is to compare the impact on clinical outcomes of 3 different treatment strategies.
- Trial name
- NCT00121446
- Testing
- tenecteplase, enoxaparin, clopidogrel
- Where
- 16 sites in Canada
- Volunteers
- 300 people
- Sponsor
- University of Alberta
Diabetes Mellitus, Type 2
Improving the Care of Diabetic Patients: A Randomized Trial of a Family Physician Office-Based Chronic Disease Care Model for Patients With Type 2 Diabetes
The purpose of the study is to determine the efficacy of a family physician practice-based model of chronic disease management (CDM) based in Primary Care Networks (PCN's) that is integrated with the Capital Health Regional…
- Trial name
- NCT00789282
- Testing
- multidisciplinary approach, multifactorial approach - for enhanced care group, reflects current patterns of care
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- University of Alberta
Advance Care Planning, Goals of Care
Trial of Advance Care Planning (ACP) & Goals of Care Designations (GCD) Discussions
The Canadian population is aging and more people are living with advanced chronic diseases. At the end of life (EOL), the use of invasive medical treatments in hospitals is increasing and associated with worse outcomes.
- Trial name
- NCT02463162
- Testing
- Conversations Matter videos
- Where
- 15 sites in Canada
- Volunteers
- 240 people
- Sponsor
- University of Alberta
Pain, Nausea
Pediatric Integrative Medicine Trial Pilot
This study will investigate if adding complementary therapies such as acupuncture, massage and reiki to inpatient pediatric care is feasible and what the effects are on outcomes such as patient symptoms, cost, safety…
- Conditions
- Pain, Nausea, Vomiting, Anxiety
- Trial name
- PIM (NCT02028832)
- Testing
- PIM consult and service provision, Usual care
- Where
- Canada
- Volunteers
- 872 people
- Sponsor
- University of Alberta
Chronic Headache, Analgesic Rebound Headache
Propofol Injection for Daily Headache
Hypothesis A single subanesthetic dose of propofol will result in improved pain and quality of life for the next 30 days in persons with chronic daily headache (CDH) Specific objectives To measure the effect of a single infusion…
- Conditions
- Chronic Headache, Analgesic Rebound Headache, Chronic Daily Headache, Headache, Intractable
- Trial name
- NCT00228267
- Testing
- Propofol
- Where
- Canada
- Volunteers
- 28 people
- Sponsor
- University of Alberta