Clinical trials: sponsored by University of Oklahoma
Creatine Absorption in Healthy Adults
Acute Pharmacokinetics of Create Wellness Gummies in Healthy Adults
The purpose of this study is to compare blood creatine levels following acute oral supplementation of Create Wellness creatine gummies to creatine monohydrate powder.
- Trial name
- NCT07579455
- Testing
- Create Wellness Creatine Gummies, Creatine Monohydrate Powder
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Nutrition Poor, Health Behavior
Technical Assistance for Child and Adult Care Food Program in Family Child Care Home
This study evaluates the effect of a nutrition technical assistance training program for family child care home providers on the food they serve young children in their care and the food environment in their home.
- Trial name
- NCT03560050
- Testing
- Nutrition assistance, Children's environmental health/comparison
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Metastatic Castration-Resistant Prostate Cancer (mCRPC)
Sipuleucel-T Based Autologous Cellular Immunotherapy for Advanced Prostate Cancer
Proposed immunotherapy with an extended course of Sipuleucel-T treatment may induce a more robust immune response and improve the anti-cancer efficacy of Sipuleucel-T in patients with metastatic Castration-Resistant Prostate…
- Trial name
- OU-SCC-EXCITE (NCT05806814)
- Testing
- Sipuleucel-T
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Oklahoma
Burns, Wound Infection
Topical Methylene Blue-Photodynamic Therapy (MB-PDT) for Burn Wound Infection
Burn wound infections remain a major source of morbidity in patients with thermal injuries and contribute to delayed healing, graft loss, and prolonged hospitalization.
- Trial name
- NCT07494773
- Testing
- Methylene Blue, Blue Light Illumination
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Oklahoma
Obesity and Overweight, Breastfeeding, Exclusive
Impact of Chia Seeds on Human Breast Milk Composition
The investigators' over-arching hypothesis is that mechanical and compositional properties of chia seeds supplemented during lactation diminish obesity-induced intestinal inflammation and barrier dysfunction.
- Trial name
- NCT07343908
- Testing
- Chia seeds
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- University of Oklahoma
Chronic Pain Due to Cancer, Pain Catastrophizing
Empowered Relief® for Cancer Survivors With Chronic Pain
This randomized controlled study to examine the efficacy of ER class in cancer survivors with chronic pain. Eligible participants will be randomly assigned to a ER class or a waitlist control condition.
- Trial name
- NCT07578376
- Testing
- Empowered Relief Course (Zoom)
- Where
- United States
- Volunteers
- 215 people
- Sponsor
- University of Oklahoma
Polycystic Ovary Syndrome
Myo-Inositol for Infertility in PCOS
This will be a prospective, double-blind randomized clinical trial of letrozole and placebo versus letrozole and inositols for up to 5 treatment cycles of ovulation induction or until pregnancy is achieved.
- Trial name
- NCT04407754
- Testing
- Inositol supplement
- Where
- United States
- Volunteers
- 168 people
- Sponsor
- University of Oklahoma
Head and Neck Cancer
"QUAD SHOT" Radiotherapy With Pembrolizumab in Patients With Recurrent Head & Neck Cancer
The purpose of this study is to test the safety of palliative "QUAD SHOT" radiotherapy combined with pembrolizumab and evaluate the effects of the combination treatment patients with recurrent cancer of head and neck.
- Trial name
- QUADSHOT (NCT04373642)
- Testing
- Pebrolizumab + QUADSHOT Radiotherapy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Oklahoma
Cigar Smoking, Tobacco Use
Cigar Legislation and Regulation in Tobacco for the Young (Project CLARITY)
This clinical trial will recruit young adults who currently use cigarillos and examine the smoking behavior and perceptions of different flavored cigarillos, product ingredients/additives impacting these perceptions, and…
- Trial name
- CLARITY (NCT07162935)
- Testing
- Cigarillo brand 1, Cigarillo brand 2, Cigarillo brand 3
- Where
- 2 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Smoking Cessation
Empowering Cessation ACS South Region
Sexual and/or gender minority (SGM) people face a disproportionate burden of cancer risk, and tobacco use is a key modifiable risk factor.
- Trial name
- CHERC (NCT06820034)
- Testing
- Empowering Cessation for the ACS South
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Endometrial Cancer
Frontline Immunotherapy Combined With Radiation and Chemotherapy in High Risk Endometrial Cancer
The purpose of this single arm, open label study is to evaluate the feasibility of pembrolizumab combined with radiation administered to the upper part of the vagina (vaginal cuff brachytherapy) followed by three cycles of…
- Trial name
- FIERCE (NCT03932409)
- Testing
- Pembrolizumab, Vaginal cuff brachytherapy (VCB), Paclitaxel
- Where
- 2 sites in United States
- Volunteers
- 45 people
- Sponsor
- University of Oklahoma
Smoking Cessation
Developing Empowering Smoking Cessation
Problem: Despite encouraging use declines in the U.S. population, tobacco is still a leading cause of preventable disease and death.
- Trial name
- ECHO (NCT06602076)
- Testing
- ECHO (Empowering Our Community & Health Outcomes)
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Oklahoma
Photophobia
Comparison Between Spectacles and Contact Lenses
Many people suffer from migraine headaches, some more so than others and a common trigger/complaint is light sensitivity, or photophobia1.
- Trial name
- NCT06905912
- Testing
- Biomedics55 Premier contact lenses, and Altius Tinted Contact Lenses
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Healthy
The Effects of Acute Melatonin Supplementation on Cardiovascular Responses to Sympathetic Activation
the purpose of this experiment is to determine if acute melatonin supplementation alters central and peripheral cardiovascular responses to a cold pressor test at rest and during dynamic exercise.
- Trial name
- NCT04831398
- Testing
- melatonin
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Fatigue
Fatigability and Cognitive Demand With Aging
This study will determine the influence of a cognitive task performed during fatiguing contractions.
- Trial name
- NCT05121272
- Testing
- cognitive task
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Alcohol Misuse, Homeless
Efficacy of a Smartphone-Based JITAI to Reduce Drinking Among Adults Experiencing Homelessness
Approximately 1 out of every 3 adults experiencing homelessness has a current alcohol use disorder (AUD). Alcohol use plays a central role in increased morbidity and mortality in this population, with some studies suggesting it…
- Trial name
- SmartT_A (NCT06821295)
- Testing
- Smart-T Alcohol, Usual Care
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Smoking Cessation, Mental Illness
Mobile App for Smoking Cessation and Mental Health
Adults with serious mental illness (SMI) represent 5% of the United States population, yet account for 30% of all cigarettes smoked and are 2 to 3 times more likely to be dependent on nicotine compared with the general…
- Trial name
- NCT04887558
- Testing
- Smart-T Mental Health and NRT, Smart-T Mental Health+ and NRT, QuitGuide + NRT
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Healthy
Resistance Training With Blood Flow Restriction
Blood flow restriction associated with resistance training is suggested to potentiate increases in muscular strength and hypertrophy.
- Trial name
- NCT05863039
- Testing
- Blood flow restriction, Regular training type 1, Regular training type 2
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Smoking Cessation
A Culturally Tailored Smartphone Application for African American Smokers
The overall objectives of this research proposal, are to (a) create a smartphone application for smoking cessation (i.e., HealthyCells), which will be achieved by integrating two pre-existing evidence-based smartphone…
- Trial name
- HC (NCT05188287)
- Testing
- HealthyCells
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Cancer Survivorship, Chemotherapy Side Effects
Remote Physical Activity Programming to Improve Outcomes in Cancer Survivors With and Without Type 2 Diabetes
The growing U.S. cancer survivor population is projected to hit 26M by 2040. Chemotherapy represents an effective cancer treatment but can diminish cancer survivors' quality of life-particularly cognitive function-through select…
- Trial name
- CICI-PA (NCT06725953)
- Testing
- Social Cognitive Theory-based, Technology-delivered Physical Activity Program
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of Oklahoma