Clinical trials: sponsored by University of Toronto
Cancer, Older Adults
Comprehensive Health Assessment for My Plan: Initial Implementation Study (CHAMP Implementation Study)
The current standard preoperative assessment does not consider the needs of older adults undergoing non-oncological surgery. To enhance the treatment decision-making and planning for older adult surgical patients, the British…
- Trial name
- NCT06464471
- Testing
- Self-reported online geriatric assessment (CHAMP)
- Where
- Canada
- Volunteers
- 210 people
- Sponsor
- University of Toronto
Overweight or Obesity, Body Weight
The Effects of Long-term Consumption of Full-fat Dairy Products on Satiety, Body Weight and Glycemic Control
The proposed study looks at the effect of long-term diet modification with or without full-fat dairy products or restrictive eating on body weight, body composition and cardiometabolic markers in healthy overweight/obese men and…
- Trial name
- NCT04399460
- Testing
- Dairy-based commercially available food products, Restrictive Eating
- Where
- 2 sites in Canada
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Obesity, Diabetes
Comparison of Pulse Chips and Commercial Snacks on Food Intake, Appetite and Blood Glucose in Healthy Young Adults
Consumers are often forced to eat fast, convenient foods and snacks ("eat on the go") in order to match the pace of their lifestyles. However, these snack options more often than not offer little health benefit to the consumer.
- Trial name
- NCT03297931
- Testing
- Corn Chips + Onion Dip, Yellow pea chip + hummus, Pinto bean chip + hummus
- Where
- Canada
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Behaviour Change, Nudging
Rectangular Collimation in Pediatric Dentistry
This project aims to investigate whether simple behavioural interventions, such as pictorial framing and traffic-light-color-coding, can positively influence pediatric dentists' decision-making in adopting rectangular collimation…
- Conditions
- Behaviour Change, Nudging, Rectangular Colllimation in Pediatric Dentistry
- Trial name
- RCPD (NCT06877117)
- Testing
- Pictorial Framing, Traffic Light Color Coding Framing
- Where
- Canada
- Volunteers
- 6,473 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Glycemic Response to Feeding in Healthy Participants, Postprandial Amino Acid Concentrations
Comparison of Dairy and Plant-based Alternatives in Adolescents and Older Adults
The purpose of the Dairy vs Plant study is to compare the effects of dairy and plant-based alternative products on blood sugar regulation and nutrient quality in adolescents and older adults.
- Conditions
- Glycemic Response to Feeding in Healthy Participants, Postprandial Amino Acid Concentrations, Appetite Regulation
- Trial name
- NCT06874400
- Testing
- Dairy, Plant-based alternative
- Where
- Canada
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Measles, Polio
A Tool Kit to Improve Vaccine Confidence in the Philippines
This cluster randomized controlled trial (RCT) aims to evaluate the feasibility and efficacy of an educational toolkit in enhancing measles, mumps, rubella (MMR) and polio vaccine confidence in the Philippines.
- Conditions
- Measles, Polio, Vaccination Hesitancy
- Trial name
- NCT06218368
- Testing
- Educational toolkit on MMR and polio vaccination
- Where
- Philippines
- Volunteers
- 5,400 people, healthy volunteers welcome
- Sponsor
- University of Toronto
ADHD
Nocebo Education to Reduce the Potential Unintended Harms of Mental Health Awareness
This project has two aims. First, the research team will confirm whether providing a mental health awareness workshop poses unintended harms by raising the rate of self-diagnosis (as opposed to a neutral workshop) and causing…
- Trial name
- NCT06638411
- Testing
- ADHD information workshop, ADHD information workshop with nocebo education, Sleep workshop
- Where
- Canada
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Prostate Cancer, Resistance Training
Feasibility of a Remotely-Delivered Resistance Training Program for Cognitive Function in Men Living With and Beyond Prostate Cancer
Prostate cancer and its treatment are associated with many long-term adverse effects including cancer-related cognitive impairment.
- Trial name
- NCT06828003
- Testing
- Resistance Training
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Toronto
Education
Online Regional Anesthesia Resources - Are They Effective?
Anatomical-based ultrasound imaging has been one of the most rapidly advancing innovations in the field of regional anesthesia in recent years.
- Trial name
- NCT05290974
- Testing
- Self exploring of available online material on supraclavicular brachial plexus block, Conventional in-person teaching on supraclavicular brachial plexus block
- Where
- Canada
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Exercise Induced Muscle Damage, Physical Activity
Walk It Off! the Influence of Physical Activity Level on the Recovery from Damaging Resistance Exercise
After completing novel activity or exercise we may experience exercise-induced muscle damage (EIMD), resulting in a period of reduced muscle function and delayed onset muscle soreness (DOMS).
- Conditions
- Exercise Induced Muscle Damage, Physical Activity, Inflammation, Exercise Recovery
- Trial name
- WIO (NCT06810271)
- Testing
- Eccentric resistance exercise
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Physical Activity, Mental Health Issue
1:1 and Group-based Exercise Intervention for Post-secondary Student Mental Health and Well-being
Post-secondary students report alarming rates of feeling overwhelmed, hopeless, anxious, and depressed. To better support student mental health, there is a well-documented need to improve the range and quality of mental health…
- Trial name
- NCT06350877
- Testing
- Physical Activity Intervention
- Where
- Canada
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Breast Cancer Females
Chronic Impacts of Endocrine Therapy on Cardiovascular and Brain Health Outcomes in Breast Cancer
Aromatase inhibitors are the most used endocrine therapy for hormone-positive breast cancer. Despite the evidence that aromatase inhibitor therapy is associated with increased risk of cardiovascular events, potentially related to…
- Trial name
- STRIVE-Chronic (NCT06776458)
- Testing
- N/A - Usual Care
- Where
- Canada
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Mobility Limitation
TIME™ at Home Randomized Controlled Trial
The goal of this randomized controlled trial is to compare the short-term effects of a virtual, community-based, task-oriented group exercise program (TIME™ at Home) with a waitlist control in community-dwelling adults with…
- Trial name
- NCT06245135
- Testing
- TIME at Home
- Where
- 4 sites in Canada
- Volunteers
- 200 people
- Sponsor
- University of Toronto
Inactivity, Physical, Aging
Oral 'Breath Test' to Measure Anabolic Sensitivity to a Protein Meal Across the Age and Physical Activity Spectrum
The purpose of this study is to determine how anabolic sensitivity, in response to the ingestion of a liquid protein meal, differs across the lifespan, between biological sexes, and with varying physical activity levels.
- Conditions
- Inactivity, Physical, Aging, Healthy Aging, Growth & Development
- Trial name
- NFRF (NCT06744491)
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Cardiovascular Diseases
HCP-facing Portfolio Diet Toolkit Validation Study
There is limited support in primary care for diet and lifestyle, the cornerstones for therapy in clinical practice guidelines. Canadian dietitian services are not covered by provincial health plans and most physicians cite a lack…
- Trial name
- NCT05915455
- Testing
- HCP-facing Portfolio Diet Infographic + Informative Video, Portfolio Diet Application
- Where
- Canada
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Breast Cancer
Exercise and Cognitive (Brain) Function in Breast Cancer Patients Getting Chemotherapy After Breast Surgery
This study will primarily identify longitudinal associations between cardiorespiratory fitness (CRF) and cognitive function pre- (baseline) to post-chemotherapy (~3 months). This will be a prospective study of 50 BCS.
- Trial name
- NCT04616300
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of Toronto
Spinal Cord Injuries
An Online Self-management Program for Spinal Cord Injury: Feasibility Study of SCI&U
Managing a spinal cord injury (SCI) is a life-long process. Within the first year of injury, more than 50% of people discharged with a SCI may require re-hospitalization due to a secondary complication, such as a urinary tract…
- Trial name
- SCI&U (NCT04474171)
- Testing
- SCI&U online health coaching program
- Where
- Canada
- Volunteers
- 63 people
- Sponsor
- University of Toronto
Sedentary Behavior, Cancer of Prostate
A Intervention for Reducing Sedentary Behaviour Among Prostate Cancer Survivors
This randomized controlled trial (RCT) will aim to examine the effect of a 12-week behavioural intervention on changing the sedentary behaviours (SB) of prostate cancer survivors (PCS) compared to a control group (FitBit-only…
- Trial name
- NCT05214937
- Testing
- Intervention, FitBit Only
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- University of Toronto
Parkinson Disease
Effects of Unblocking the Full Potential of Percept PC IPG
Population Size and Eligible Patients: The study will enroll patients with Parkinson's disease (n=30) who had an IPG replacement from Activa PC (older generation of neurostimulator) to Medtronic PerceptTM PC (newer generation of…
- Trial name
- NCT06127771
- Testing
- Programming DBS using Percept PC neurostimulator's full potential
- Where
- Canada
- Volunteers
- 19 people
- Sponsor
- University of Toronto
Vaccination, Vaccination Pain
CARD for Community Pharmacy Vaccinations - Phase 2
This study is phase 2 of a cluster trial integrating the CARD (Comfort Ask Relax System) in community pharmacies affiliated with Wholehealth Pharmacy Partners.
- Conditions
- Vaccination, Vaccination Pain, Vaccination Reaction, Vaccination Pharmacy
- Trial name
- NCT06666868
- Testing
- Sustained CARD, First-time CARD
- Where
- Canada
- Volunteers
- 500 people
- Sponsor
- University of Toronto