Clinical trials: sponsored by University of Washington
Dry Eye Syndromes
Ocular Surface Microbiome
The purpose of this study is to collect samples from the surface of eyelids to try to grow and identify bacteria or fungus that might be present, and to try to understand why people have dry eye symptoms.
- Trial name
- NCT02298881
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Washington
Sacroiliitis, Sacroiliac Joint Pain
Imaging for SIJ Injection Therapy
The Research question: Among two standard image guidance techniques [2-dimension (2-D) conventional Fluoroscopy Versus 3-dimension (3-D) Cone-Beam Computed Tomography (CBCT)], which is the better guidance for Sacroiliac Joint…
- Trial name
- NCT03992053
- Testing
- sacroiliac joint injection
- Where
- United States
- Sponsor
- University of Washington
Oppositional Defiant Disorder
Parent Training and Emotion Coaching for Children With Limited Prosocial Emotions
The proposed research will focus on the development of a brief emotion-coaching (EC) parenting program (which directly targets child emotion awareness/recognition and affective empathy), that will be combined with a…
- Trial name
- HNC-EC (NCT02409992)
- Testing
- Parent Training plus Emotion Coaching, Parent Training only
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- University of Washington
Multiple Sclerosis
Waking Hypnosis in the Treatment of MS-related Fatigue
The proposed study is a single-center, single-blind three-group randomized (1:1:1) controlled trial (RCT) comparing two hypnosis interventions to waitlist control efficacy for MS-related fatigue.
- Trial name
- POWER-UP (NCT04429789)
- Testing
- Active-Alert Hypnosis, Traditional Hypnosis
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Washington
Respiratory Distress Syndrome, Adult, Head Injuries, Closed
Hypertonic Saline With Dextran for Treating Hypovolemic Shock and Severe Brain Injury
The purpose of this study is to evaluate the clinical outcome of patients following blunt traumatic injury with hypovolemic shock, who receive either lactated ringer's solution or hypertonic saline with dextran (HSD)…
- Conditions
- Respiratory Distress Syndrome, Adult, Head Injuries, Closed, Shock, Shock, Traumatic
- Trial name
- NCT00113685
- Testing
- Hypertonic Saline-Dextran Solution, Lactated Ringer's Solution
- Where
- United States
- Volunteers
- 209 people
- Sponsor
- University of Washington
Chronic Pain, Pain
Classifying and Predicting Long-term Pain and Function in Older Adults
This project will use novel methods to detect clinically meaningful subgroups of older adults based on long-term trajectories of bothersome pain and function.
- Trial name
- NCT04864223
- Where
- United States
- Volunteers
- 6,783 people, healthy volunteers welcome
- Sponsor
- University of Washington
Opioid Use, Pain, Postoperative
Collaborative Opioid Taper After Trauma: Preventing Opioid Misuse and Opioid Use Disorder
The investigators will enroll 100 participants using a randomized control trial design to implement and evaluate an individualized opioid taper program supporting rural Primary Care Physicians (PCPs) caring for patients with…
- Conditions
- Opioid Use, Pain, Postoperative, Opioid Use, Unspecified, Trauma
- Trial name
- NCT04275258
- Testing
- Provide assistance to subject's rural PCP pertaining to subject/patient pain management goals and opioid taper plan
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Washington
Perinatal Depression
Collaborative Care for Perinatal Depression Care in Vietnam
Depression is the most common medical disorder of pregnancy, and suicide, most frequently found in women with depression, is a major source of maternal mortality.
- Trial name
- NCT04650334
- Testing
- Collaborative Care
- Where
- 2 sites in Vietnam
- Volunteers
- 100 people
- Sponsor
- University of Washington
Perinatal Depression
Remote Supervision for Implementing Collaborative Care for Perinatal Depression
This study evaluates the impact of a longitudinal remote consultation (LRC) implementation strategy for collaborative care depression treatment among perinatal women.
- Trial name
- MInD-I (NCT02976025)
- Testing
- Longitudinal Remote Consultation, Collaborative Care
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Washington
Epilepsy Intractable
Microgrid II - Electrocorticography Signals for Human Hand Prosthetics
Neurologic disease with loss of motor function is a major health burden. Brain-computer interfaces (BCI) are systems that use brain signals to power an external device, such as a communication board or a prosthetic device, which…
- Trial name
- NCT03289572
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Washington
Pediatric Abdominal Pain
Managing Childhood Abdominal Pain
Functional abdominal pain (FAP) is a common complaint of childhood, associated with considerable health care costs, disruption of normal activity, emotional distress, and long-term health effects.
- Trial name
- MCAP (NCT01620606)
- Testing
- Cognitive Behavioral Therapy & Social Learning, Education and Support
- Where
- 3 sites in United States
- Volunteers
- 316 people
- Sponsor
- University of Washington
Epilepsy, Brain Injury
Optimization of Human Cortical Stimulation
We will observe epileptic patients who already have electrodes implanted on the brain and are receiving high-level brain stimulation for clinical purposes while testing their motor and language function.
- Trial name
- BCI (NCT01198964)
- Testing
- Low-level cortical stimulation
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Washington
Thrombocytopenia
American Trial Using Tranexamic Acid in Thrombocytopenia
The purpose of this study is to evaluate the usefulness of antifibrinolytic therapy with tranexamic acid (TXA) in preventing bleeding in patients who are thrombocytopenic due to primary bone marrow disorders or chemotherapy…
- Trial name
- A-TREAT (NCT02578901)
- Testing
- Tranexamic Acid
- Where
- 3 sites in United States
- Volunteers
- 330 people
- Sponsor
- University of Washington
Pneumonia, Viral
Severe Acute Respiratory Infection - Preparedness (COVID-19 and Influenza)
Severe Acute Respiratory Infection (SARI) is defined by the World Health Organization (WHO) as acute respiratory infection with a history of fever ≥38°C and cough for less than 10 days duration that requires hospital admission.
- Trial name
- SARI-PREP (NCT04786301)
- Where
- 2 sites in United States
- Volunteers
- 1,200 people
- Sponsor
- University of Washington
Posttraumatic Stress Disorder
Piloting Acute Care to Primary Care Linkage of Safety Net Patients
This pilot study will evaluate the implementation of a stepped care intervention that combines Cognitive-Behavioral Therapy, Motivational Interviewing, psychotropic medications, and information technology innovations at a level 1…
- Trial name
- TSOS III (NCT01347541)
- Testing
- Cognitive Behavioral Therapy, Motivational Interviewing, FDA-Approved Anti-Anxiety Medications
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Washington
Plaque Induced Gingivitis
Induced Gingivitis & Intra-oral Imaging
Using an experimental, non-invasive intra-oral imaging device, this study evaluates the effects on the gingival tissue when oral hygiene is stopped in a section of the mouth for two weeks and gingivitis develops.
- Trial name
- NCT03750955
- Testing
- Plaque induced gingivitis, Oral hygiene maintenance
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Washington
Adult Acute Myeloid Leukemia, Adult Myelodysplastic Syndrome
Outpatient Induction Chemotherapy in Treating Patients With Acute Myeloid Leukemia or Advanced Myelodysplastic Syndrome
This pilot clinical trial studies the feasibility of having induction chemotherapy in an outpatient setting. Patients with acute leukemia (AML) or advanced myelodysplastic syndrome (MDS), at least 18 years of age will be…
- Trial name
- NCT01807091
- Testing
- Chemotherapy
- Where
- 9 sites in United States
- Volunteers
- 17 people
- Sponsor
- University of Washington
Stage III Ovarian Epithelial Cancer, Stage III Ovarian Germ Cell Tumor
Vaccine Therapy in Treating Patients With Stage III-IV or Recurrent Ovarian Cancer
This phase I trial is studying the side effects of vaccine therapy in treating patients with stage III-IV or recurrent ovarian cancer.
- Conditions
- Stage III Ovarian Epithelial Cancer, Stage III Ovarian Germ Cell Tumor, Stage IV Ovarian Epithelial Cancer, Stage IV Ovarian Germ Cell Tumor
- Trial name
- NCT01322802
- Testing
- pUMVC3-hIGFBP-2 multi-epitope plasmid DNA vaccine, laboratory biomarker analysis
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Washington
Bladder Carcinoma
TracelT Hydrogel in Localizing Bladder Tumors in Patients Undergoing Radiation Therapy for Bladder Cancer
This pilot clinical trial studies how well TracelT hydrogel works in localizing bladder tumors in patients undergoing radiation therapy for bladder cancer.
- Trial name
- NCT03125226
- Testing
- Polyethylene Glycol Hydrogel
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Washington
Cardiac Surgery, Protein Metabolomics
Cerebral Monitor Guided Therapy on Cerebral Outcomes After Cardiac Surgery
The purpose of this study is to compare patients' metabolomic profiles who are managed with a brain monitor that measures cerebral oxygen to those who are managed by conventional measures to hopefully decrease postoperative…
- Conditions
- Cardiac Surgery, Protein Metabolomics, Cerebral Function, Cardiopulmonary Bypass
- Trial name
- NCT03316183
- Testing
- Perioperative and postoperative management
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Washington
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