Clinical trials: sponsored by Zagazig University
Crohn Disease
Effect of Biologic Therapy on Surgical Outcomes for Perforated Crohn's Patients
crohn's disease patients who present by intestinal perforation as the first presentation are hard to deal with. Surgical techniques as anastmosis or diversion stoma and active course of the disease may greatly affect the quality…
- Trial name
- NCT06511921
- Testing
- early biologic therapy, late biologic therapy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Zagazig University
Pilonidal Sinus Treatment
The Outcomes of Keystone Perforator Island Flap Versus Lay Open in Re-recurrent Pilonidal Sinus Disease
Pilonidal disease is a common and annoying problem with a fair recurrence rate. Every time of recurrence more skin is needed to cover the defect and if left open healing is supposed to be prolonged.
- Trial name
- NCT06741449
- Testing
- keystone flap, lay open
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Zagazig University
Bronchial Asthma
Oral Intake of Mg in Controlled Asthmatic Patients
The goal of this clinical trial is to assess the efficacy of oral magnesium supplements in controlled asthmatic patients for proper effective asthma management to reduce frequency of asthma exacerbation \& to test the effect…
- Trial name
- Mg in asthma (NCT06721247)
- Testing
- Magnesium, ICS+LABA
- Where
- Egypt
- Volunteers
- 166 people
- Sponsor
- Zagazig University
Cancer Prostate
Prospective Validation of PSMA-RADS
This is a prospective, multicenter study aimed at evaluating the diagnostic accuracy and reliability of the Prostate-Specific Membrane Antigen Reporting and Data System (PSMA-RADS) version 1.0 in detecting prostate cancer using…
- Trial name
- PSMA-RADS (NCT06359717)
- Where
- Egypt
- Volunteers
- 477 people
- Sponsor
- Zagazig University
Anal Stenosis
V-Y Flap for Anal Stenosis
anal stenosis is a common complication after massive open hemorrhoidectomy. it interferes with the patient daily activities. Many interventions were described, but there is no standard treatment.
- Trial name
- NCT06860906
- Testing
- V-Y advancement flap
- Where
- Egypt
- Volunteers
- 25 people
- Sponsor
- Zagazig University
Adhesive Peritoneal Band
Intra-Abdominal Instillation Of Fresh Frozen Plasma Versus Corticosteroids In Prevention Of Recurrent Attacks Of Adhesive Intestinal Obstruction: A 2 Years' Experience Clinical Study
Adhesive Intestinal obstruction is an inevitable complication of abdominal surgery with significant morbidity associated with poor quality of life and predispose to repeated hospitalization.
- Trial name
- NCT06859307
- Testing
- intra-abdominal instillation of corticosteroids, intra-abdominal instillation of fresh frozen plasma
- Where
- 2 sites in Egypt
- Volunteers
- 176 people
- Sponsor
- Zagazig University
Obesity and Obesity-related Medical Conditions
Outcomes Of Laparoscopic Sleeve Gastrectomy In Patients With Hypothyroidism And Depression
Sleeve gastrectomy (SG) continues to be one of the most popular bariatric procedures all over the world. It has been established that obesity is a predisposing factor for several comorbidities, including life-threatening…
- Trial name
- NCT06859320
- Testing
- laparoscopic sleeve gastrectomy
- Where
- 2 sites in Egypt
- Volunteers
- 24 people
- Sponsor
- Zagazig University
Lower Limb Fracture
Combined Lumbar and Sacral Branches Block Through the Ilio-Psoas Muscle Spaces for Analgesia of Lower Limb Surgeries
lumbosacral plexus block (LSPB) has been widely applied in orthopedics departments due to its advantages, including reduction in the application of opiates, decreasing the occurrence of acute pain, promoting early activation, and…
- Trial name
- NCT06019754
- Testing
- one point combined Lumbar and sacral plexus block
- Where
- Egypt
- Volunteers
- 56 people
- Sponsor
- Zagazig University
Appendicitis Acute
Efficacy of LigaSure Versus Harmonic Scalpel US in Laparoscopic Appendectomy in Management of Acute Appendicitis
Background Acute appendicitis is the most frequent abdominal surgical emergency worldwide, peaking in incidence between the second and third decade of life.
- Trial name
- NCT07091110
- Testing
- laparoscopic appendectomy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Zagazig University
Airway Complication of Anesthesia
Role of Airway Topicalization in Awake Fiberoptic Intubation
Airway management is an integral part of general anesthesia. Difficult airway management may lead to various adverse events such as airway trauma, up to cardiopulmonary arrest.
- Trial name
- NCT06720220
- Testing
- Dexmedetomidine Hydrochloride, Nebulization, Atomization
- Where
- Egypt
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Adenotonsillectomy
Intranasal Dexmedetomidine, Ketamine or Midazolam for Anxiety and Respiratory Complications in Children
This study is being done to find out which of three medications-dexmedetomidine, ketamine, or midazolam-is best at reducing anxiety and breathing problems in children having surgery to remove their tonsils and adenoids.
- Trial name
- INPERM (NCT07072117)
- Testing
- Intranasal Dexmedetomidine as a Premedication for Prevention of Anxiety & Respiratory Complications, Intranasal Ketamine as a Premedication for Prevention of Anxiety and Respiratory Complications, Intranasal Midazolam as a Premedication for Prevention of Anxiety and Respiratory Complications
- Where
- Egypt
- Volunteers
- 148 people
- Sponsor
- Zagazig University
Hip Fractures
Circum-Psoas Blocks Versus Combined Lumbar and Sacral Plexus Blocks in Hip Fracture Surgery
Hip fracture (HF) is one of the major worldwide problems that constitute a significant mortality rate, ranging from 14- 36% in the first year after injury, and is associated with profound temporary and sometimes permanent…
- Trial name
- NCT05660603
- Testing
- control, LSP, CP
- Where
- Egypt
- Volunteers
- 63 people
- Sponsor
- Zagazig University
Cervical Spine Surgery
Multifidus Cervicis and Inter-Semispinal Plane Blocks in Analgesia After Cervical Spine Surgery
Major spine surgery with multilevel instrumentation is followed by a large amount of opioid consumption, significant pain, and difficult mobilization Pain is one of the main factors limiting ambulation, increasing the risk of…
- Trial name
- NCT06083298
- Testing
- control group, MCP group, ISP group
- Where
- Egypt
- Volunteers
- 105 people
- Sponsor
- Zagazig University
Analgesia
Bilateral Rhomboid Intercostal Block for Perioperative Analgesia in Patients Undergoing Bilateral Reduction Mammoplasty
Bilateral reduction mammoplasty is one of the most commonly performed breast surgery. The Postoperative pain following it should be minimized.
- Trial name
- NCT06225895
- Testing
- general anesthesia, Erector spinae plane block, a rhomboid intercostal nerve block
- Where
- 2 sites in Egypt
- Volunteers
- 72 people
- Sponsor
- Zagazig University
Hip Arthropathy
Anterior Iliopsoas Muscle Space Block Versus Supra-iliac Anterior Quadratus Lumborum Block in Total Hip Arthroplasty
Approximately 1.66 million hip fractures happen in a year worldwide. About 95% of these fractures happen in individuals older than 60 years.
- Trial name
- NCT05556759
- Testing
- control, IPS, Supra-iliac QL
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Zagazig University
Irritable Bowel Syndrome
Prevalence of Irritable Bowel Syndrome Among Egyptian Medical Students
Assess prevalence of irritable bowel syndrome among both medical students and medical interns, and the most significant risk factors of this condition, and highlight the association between IBS symptoms, anxiety \& depression.
- Trial name
- NCT07033936
- Testing
- Questionnaire
- Where
- Egypt
- Volunteers
- 1,093 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Overactive Bladder Syndrome
Prevalence And Risk Factors of Overactive Bladder Syndrome Among Egyptian Medical Students, and Their Impact On Health-Related Quality Of Life
Overactive bladder (OAB) is defined as sudden, urgent desire to urinate (urgency) accompanied by frequency and nocturia, with or without urgent urinary incontinence in the absence of urinary tract infection (UTI).
- Trial name
- NCT07044778
- Testing
- Questionnaire
- Where
- Egypt
- Volunteers
- 1,003 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Diaphragmatic Eventration
Two Procedures for Uniportal Video Assisted Thoracoscopic Surgery to Treat Severe Cases of Diaphragmatic Eventration in Adult
highly elevated abnormal diaphragm is lowered to normal position by runuing suture accordion shaped or cut part of diphragm by stabler
- Trial name
- NCT07035366
- Testing
- stabled resection, running sutures
- Where
- 3 sites in Egypt
- Volunteers
- 30 people
- Sponsor
- Zagazig University
Preemptive Analgesia
Analgesic Effect of Infraspinatus-teres Minor Block for Pre-emptive Analgesia in Patients Undergoing Shoulder Surgeries.
The aim of the study to evaluate the efficacy of the infraspinatus-teres minor (ITM) block in improving pre-emptive analgesia, reducing opioid consumption, and enhancing the overall analgesic effect in patients undergoing…
- Trial name
- NCT06999460
- Testing
- Infraspinatus teres minor block group, Control group
- Where
- 2 sites in Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Warts, Human Papilloma Virus
Candida Antigen and Bivalent HPV Vaccine in the Treatment of Multiple Warts
To follow up the efficacy and safety of Candida antigen, bivalent HPV vaccine in treatment of common warts either mono or combined intralesional therapy
- Trial name
- NCT05291845
- Testing
- Candida antigen vaccine, Bivalent HPV vaccine
- Where
- Egypt
- Volunteers
- 162 people
- Sponsor
- Zagazig University