Clinical trials: open to volunteers, sponsored by Zagazig University
Chronic Obstructive Pulmonary Disease (COPD), With Poitive H Pylori
Impact of Eradication Therapy on Helicobacter Pylori Infection With Chronic Obstructive Pulmonary Disease:
Helicobacter pylori (HP) is a well-established pathogen responsible for chronic gastritis and peptic ulcer disease. Its presence has been implicated in the development of gastric malignancies such as adenocarcinoma and…
- Trial name
- NCT07574879
- Testing
- Eradication of Helcobacter Pylori
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- Zagazig University
Craniotomy Surgery
Sphenopalatine Ganglion Block Combined With Either Scalp Nerve Block or Local Wound Infiltration for Postoperative Analgesia in Adult Patients Undergoing Craniotomy: A Randomized Controlled Trial
The use of multimodal regional analgesia (scalp block, local scalp infiltration, and sphenopalatine ganglion block) for postoperative pain management after craniotomy
- Trial name
- NCT07886034
- Testing
- Group (c): control group patients will receive general anesthesia., Group (SS): Sphenopalatine Ganglion Block with either Scalp Nerve Block, Group (SL): patients will receive Sphenopalatine Ganglion Block with local wound infiltration
- Volunteers
- 54 people
- Sponsor
- Zagazig University
Postoperative Pain After Spinal Surgery
Modified Thoracolumbar Interfascial Plane Block vs Retrolaminar Block for Pain in Lumbar Spine Surgeries
This prospective randomized double-blind study aims to compare the efficacy of modified Thoracolumbar Interfascial Plane (mTLIP) block versus Retrolaminar block for postoperative pain control in patients undergoing elective…
- Trial name
- NCT07883616
- Testing
- Morphine, Bupivacaine, Dexamethasone
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Zagazig University
Difficult Intubation, Obesity
Modified El-Ganzouri Risk Index for Predicting Difficult Intubation in Obese Patients
This observational study aims to compare the predictive performance of the Modified El-Ganzouri Risk Index (MEGRI) incorporating anthropometric ratios with the original El-Ganzouri Risk Index (EGRI) for predicting difficult…
- Trial name
- MEGRI (NCT07857395)
- Testing
- No intervention
- Where
- Egypt
- Volunteers
- 114 people
- Sponsor
- Zagazig University
Opioid Free Anesthesia, Opioid Based Anesthesia
Intraoperative Infusion of Dexmedetomidine Versus Lidocaine or Magnesium Sulphate for Enhanced Quality of Recovery After Spine Surgery Fixation
Thoracolumbar fixation is a major spine surgery; it is performed to stabilize the spine after trauma, deformity or advanced degenerative disease.
- Conditions
- Opioid Free Anesthesia, Opioid Based Anesthesia, Spine Fixation Surgeries, Opiod-Related Disorders
- Trial name
- NCT07843953
- Testing
- Group ( L): LICOCAINE, GROUP Dexmedetomidine, Group M: Magnesium sulphate
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Mechanical Ventilation Complication, Ventilator Induced Lung Injury
Mechanical Power and Mortality in Mechanically Ventilated Adults
This prospective observational cohort study aims to investigate the relationship between mechanical power during the first 72 hours of invasive mechanical ventilation and 28-day mortality in mechanically ventilated adult patients…
- Conditions
- Mechanical Ventilation Complication, Ventilator Induced Lung Injury, ARDS, ICU Mortality (Survival Rate)
- Trial name
- NCT07836153
- Where
- Egypt
- Volunteers
- 116 people
- Sponsor
- Zagazig University
Atrophic Acne Scarring
Poly-L-Lactic Acid in Atrophic Acne Scars
Background: Management of atrophic acne scars remains challenging due to their heterogeneous morphology and suboptimal response to conventional therapies.
- Trial name
- NCT07523217
- Testing
- injectable PLLA, PLLA threads
- Where
- Egypt
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Discitis of Thoracic Region
Parascapular Sub Iliocostalis Plane Block Versus Thoracic Paravertebral Plane Block for Traumatic Multiple Rib Fractures
Pain control of rib fractures is essential for not only primary pain relief but also preventing secondary complications such as atelectasis or pneumonia which increase the hospital stay, as well as the transition to chronic pain.
- Trial name
- NCT07493473
- Testing
- Thoracic paravertebral block, Parascapular Sub-Iliocostalis Plane Block
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Zagazig University
Analgesia
Tourniquet Pain Prevention During Distal Upper Limb Surgery
Post-tourniquet pain remains a common problem. It disturbs the quality of anesthesia during brachial plexus block for distal upper-limb surgery.
- Trial name
- NCT07784426
- Testing
- Selective ultrasound guided Intercostobrachial nerve block, Serratus anterior plane block
- Volunteers
- 90 people
- Sponsor
- Zagazig University
Analgesia
Analgesia for Perineal Surgeries in High-risk Pediatric Patients
Perioperative pain management in pediatric patients, especially for anorectal and penile surgeries, presents significant challenges for anesthetists.
- Trial name
- NCT07602894
- Testing
- Systemic analgesia, Sacral multifidus plane block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Zagazig University
Tricuspid Valve Disease
Tricuspid Valve Reconstruction Using the Right Atrial Appendage
we use part of the cardiac chambre for replacement of destroyed valve on right side of the heart
- Trial name
- NCT07761273
- Testing
- Tricuspid Valve Reconstruction, tricuspid valve replacement
- Where
- 3 sites in Egypt
- Volunteers
- 30 people
- Sponsor
- Zagazig University
Analgesia
Radiofrequency in Knee Osteoarthritis
Knee osteoarthritis is one of the most common causes of chronic pain and disability worldwide, particularly in middle-aged and elderly populations.
- Trial name
- NCT07700784
- Testing
- Laser genicular nerve ablation, Conventional radiofrequency genicular nerve ablation
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Atrophic Scar
Exososmes in Atrophic Scars Management
Lay Summary (Simple Explanation) Atrophic scars are depressed scars that form when the skin does not heal properly, commonly seen after acne or injuries.
- Trial name
- NCT07569666
- Testing
- Intralesional exosomes, Intralesional Saline
- Where
- Egypt
- Volunteers
- 12 people
- Sponsor
- Zagazig University
Postherpetic Neuralgia ( PHN )
Intradermal Exosomes, Platelet-Rich Plasma, and Steroids for Post-Herpetic Neuralgia
This randomized controlled clinical trial will evaluate and compare the efficacy and safety of intradermal injection of exosomes, platelet-rich plasma, and corticosteroid in patients with post-herpetic neuralgia.
- Trial name
- NCT07565844
- Testing
- Exosomes, PRP, Corticosteroids
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Zagazig University
Supraglottic Airway Devices, Laryseal Clear Laryngeal Mask
Clinical Performance of Laryseal Clear Versus Ambu Aura 40 Laryngeal Mask Airway for Preschool Children
Preschool children have specific anatomical and physiological characteristics which necessitates careful selection of an appropriate airway management device.
- Trial name
- NCT07553247
- Testing
- LarySeal clear Group, Ambu Aura40 Group
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- Zagazig University
Onychomycosis
Isotretinoin Versus Excimer Light an Adjuvant in Treating Onychomycosis
3 groups of patients with onychomycosis will be recruited. Group A will receive itraconazole alone. Group B will receive itraconazole + low dose isotretinoin and group C will be treated with itraconazole + excimer light sessions.
- Trial name
- NCT06485505
- Testing
- ISOtretinoin 10 MG, excimer light, Itraconazole 200 mg
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Zagazig University
Sedation During GI Endoscopy
Comparison Between Two Drugs in Sedation of Upper GI Endoscopy
The goal of this clinical trial is to compare time of sedation between two drugs administered to patients undergoing upper gastrointestinal endoscopy Primary outcome : Time of sedation : is the time to reach sedation score of 5…
- Trial name
- NCT07423676
- Volunteers
- 52 people
- Sponsor
- Zagazig University
Knee Arthroplasty, Total
Comparison Between Combined Biceps Femoris Short Head Block and Adductor Canal Block Versus Genicular Nerve Block
The purpose of this study is to compare the analgesic outcomes (time to first analgesic request, total amount of analgesic consumption, and pain scores) following total knee arthroplasty by either combined biceps femoris short…
- Trial name
- NCT07418307
- Testing
- Combined biceps femoris short head block and adductor canal block, Genicular nerve block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Zagazig University
Alopecia Areata
Combined Microneedling With Either 1% Lactic Acid Solution or Vitamin D3 or Triamcinolone Acetonide in The Treatment of Alopecia Areata
Alopecia areata (AA) is an immunologically mediated disease characterized by non-scarring hair loss (Madni and Shapiro, 2000). AA is presented by rapid and complete hair loss in one or more round or oval patches, usually on the…
- Trial name
- NCT06327581
- Testing
- Lactic Acid, vit D, Triamcinolone Acetonide
- Where
- Egypt
- Volunteers
- 88 people
- Sponsor
- Zagazig University
Kidney Stones
Dual Approach External Oblique Fascial Plane Block Versus Erector Spinae Plane Block for Post Operative Analgesia in Percutaneous Nephrolithotomy
Here is a patient-friendly, ClinicalTrials.gov-compliant Brief Summary written in plain language, avoiding technical jargon as much as possible while remaining accurate.
- Trial name
- BLOCK-PCNL (NCT07359391)
- Testing
- Erector Spinae Plane Block, Dual External Oblique Fascial Plane Block, General Anesthesia
- Volunteers
- 90 people
- Sponsor
- Zagazig University