Clinical trials: sponsored by Shirley Ryan AbilityLab
Spinal Cord Injuries
Training Therapists in Motivational Interviewing
The purpose of this study is to test the efficacy of a Motivational Interviewing intervention on therapy participation as performed by physical and occupational therapists in an inpatient setting with patients with spinal cord…
- Trial name
- NCT03322202
- Testing
- Motivational Interviewing
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Shirley Ryan AbilityLab
Parkinson Disease
Motivational Interviewing and Physical Activity Change in Parkinson's Disease
The purpose of this study is to test the efficacy of a 6-month telephone-based motivational interviewing intervention and a web-based application intervention to improve physical activity in participants with Parkinson's Disease.
- Trial name
- NCT03329833
- Testing
- Motivational Interviewing, Web-based application
- Where
- 2 sites in United States
- Volunteers
- 44 people
- Sponsor
- Shirley Ryan AbilityLab
Parkinson Disease, Mild Cognitive Impairment
Mild Cognitive Impairment and Endurance Exercise in Parkinson's Disease
The overall objective of this study is to determine how high intensity endurance exercise affects both cognition and the signs and symptoms of Parkinson's disease as well as if certain brain structures and functions also change…
- Trial name
- NCT03542474
- Testing
- High Intensity Endurance Exercise
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Northwestern University
Spinal Cord Injury
Identify Training Strategies for Progressing Exoskeleton Users Towards Everyday Functional Ambulation
Many people with spinal cord injury are no longer able to walk and must use wheelchairs for mobility. These individuals experience greater rates of depression and lower quality of life.
- Trial name
- NCT02104622
- Testing
- ReWalk Rehabilitation 2.0
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Shirley Ryan AbilityLab
Cerebrovascular Accident (CVA), Stroke
Evaluating the Indego Exoskeleton for Persons With Hemiplegia Due to CVA
The purpose of this study is to evaluate the safety and effectiveness of the Indego exoskeleton as a gait training tool for individuals with hemiplegia due to Cerebrovascular Accident (CVA).
- Conditions
- Cerebrovascular Accident (CVA), Stroke, Hemiplegia
- Trial name
- NCT03054064
- Testing
- Indego Exoskeleton
- Where
- 7 sites in United States
- Volunteers
- 48 people
- Sponsor
- Parker Hannifin Corporation
Stroke
Development of Walk Assist Device to Improve Community Ambulation
Hypothesis/Specific Aims: The purpose of this study is to determine the effect of training with the Stride Management Assist (SMA) device vs.
- Trial name
- NCT01994395
- Testing
- The Stride Management Assist (SMA) System, Impairment based therapy
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Shirley Ryan AbilityLab
Transfemoral Amputees
Thigh Reduction Surgery of Above Knee Amputee Residual Limbs to Improve Prosthesis Fit and Patient Outcomes
The purpose of our study is to improve the fit and function of prosthetic sockets for above the knee amputees through the use of an outpatient thigh reduction surgical procedure.
- Trial name
- NCT02346019
- Testing
- Medial thighplasty with or without thigh liposuction
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Shirley Ryan AbilityLab
Aphasia, Stroke
Enhancing Written Communication in Persons With Aphasia
The purpose of this study is to evaluate whether a computerized speech-language treatment delivered by a virtual therapist (Oral Reading for Language in Aphasia (ORLA) + Writing) results in improved written communication skills…
- Trial name
- NCT01790880
- Testing
- ORLA, ORLA + Writing
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Shirley Ryan AbilityLab
Multiple Sclerosis, Relapsing-Remitting
Acute Intermittent Hypoxia in Persons With Multiple Sclerosis
The overall objective of this project is to investigate the effectiveness of Acute Intermittent Hypoxia (AIH), to improve muscle strength and activity level in individuals with relapsing-remitting MS.
- Trial name
- NCT04280484
- Testing
- Intermittent Hypoxia
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Shirley Ryan AbilityLab
Spinal Cord Injuries
Timing and Dosage of Acute Intermittent Hypoxia in Persons With SCI
This study will utilize short duration and mild levels of reduced oxygen (hypoxia) to induce spinal plasticity while evaluating the appropriate timing schedule for this intervention, as well as, the effects of superimposing…
- Trial name
- NCT03774043
- Testing
- Acute Intermittent Hypoxia
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Shirley Ryan AbilityLab
Spinal Cord Injuries
Daily Intermittent Hypoxia and Task-Specific Upper Limb Training in Persons With Chronic Incomplete SCI
The purpose of this research study is to investigate the effectiveness of a combinatorial therapy of breathing low oxygen in short bursts-acute intermittent hypoxia (AIH) and upper limb training on arm strength and function, and…
- Trial name
- NCT03262766
- Testing
- Acute Intermittent Hypoxia (AIH), Upper extremity training
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Shirley Ryan AbilityLab
Stroke
Very Intensive Variable Repetitive AmbulatioN Training
The overall objective of this subproject is to evaluate the individual and paired contributions of intensity and variability of stepping training on lower extremity (LE) function, health and community participation in patients…
- Trial name
- VIVRANT (NCT02507466)
- Testing
- exercise
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Shirley Ryan AbilityLab
Spinal Cord Injury
Motor Learning in a Customized Body-Machine Interface
People with tetraplegia often retain some level of mobility of the upper body. The proposed study will test the hypothesis that it is possible to develop personalized interfaces, which utilize the residual mobility to enable…
- Trial name
- BMI (NCT01608438)
- Testing
- Customizing the Body-Machine Interface
- Where
- United States
- Volunteers
- 157 people
- Sponsor
- Shirley Ryan AbilityLab
Transfemoral Amputation, Unilateral Traumatic Amputation of Leg at or Above Knee
Functional Outcomes in Dysvascular Transfemoral Amputees
In older adults, poor circulation in the lower extremities leads to serious health complications including limb loss. In addition, individuals with dysvascular disease also suffer from other co-morbidities like diabetes, coronary…
- Trial name
- CLEG (NCT01537211)
- Testing
- C leg compared to subject's mechanical leg (Otto Bock)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Shirley Ryan AbilityLab
Back Pain
LifeWalker Upright Walker vs. Conventional Rollator Walker and Predicate Device
The purpose of this project is to evaluate if the LifeWalker Upright walker is improves walking and reports of pain compared to a conventional rollator and predicate walker device.
- Trial name
- NCT02968277
- Testing
- LifeWalker Upright, Predicate Device, Standard Rollator
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Shirley Ryan AbilityLab
Stroke
Walk Assist Device to Improve Community Ambulation
The goal of this research study was to examine the immediate effects of a prototype wearable robotic stride management assist device (SMA) designed by Honda R\&D® on clinical walking performance, walking energetics, gait…
- Trial name
- NCT03222505
- Testing
- Honda Stride Assist Device ON, No Device Worn
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Shirley Ryan AbilityLab
Traumatic Brain Injury, Coma
The Efficacy of Familiar Voice Stimulation During Coma Recovery
The purpose of the study is to determine whether familiar vocal stimulation, provided during coma recovery, improves outcomes for persons who are unconscious after severe TBI.
- Conditions
- Traumatic Brain Injury, Coma, Vegetative State, Minimally Conscious State
- Trial name
- FAST (NCT00557076)
- Testing
- Familiar Auditory Sensory Training
- Where
- 3 sites in United States
- Volunteers
- 21 people
- Sponsor
- VA Office of Research and Development
Spinal Cord Injuries
Supportive Wheelchair Back Compared to Fabric Back
This study tests using a wheelchair back that supports the spine in a neutral position and one that allows the spine and pelvis to fall into a posterior pelvic tilt.
- Trial name
- NCT03962582
- Testing
- Matrix back
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Shirley Ryan AbilityLab
Spinal Cord Injury
Monoaminergic Modulation of Motor Function in Subacute Incomplete Spinal Cord Injury (SCI)
The primary goal of the proposed clinical trial is to investigate the combined effects of walking training and monoaminergic agents (SSRIs and TIZ) on motor function of individuals in sub-acute (2-7 mo) human motor incomplete…
- Trial name
- NCT01753882
- Testing
- Lexapro
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Shirley Ryan AbilityLab
Spinal Cord Injury
Serotonergic Modulation of Motor Function in Subacute and Chronic SCI
The manifestation of weakness and involuntary reflexes following motor incomplete spinal cord injury (SCI) may be partly a result of damage to descending pathways to the spinal cord that release serotonin.
- Trial name
- NCT01788969
- Testing
- Lexapro
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Shirley Ryan AbilityLab