Clinical trials: sponsored by National Taiwan University Hospital
Diabetes
AI-CIMCare Chatbot" to Enhance Complementary and Integrative Medicine (CIM)
Performance analysis of the AI-CIMCare Chatbot is an essential way to ensure its impact on the promotion of patient-based outcomes in patients with diabetes.
- Trial name
- AI-CIMCare (NCT07835061)
- Testing
- AI-CIMCare Chatbot, Empowerment Application for CAM Health Education
- Where
- Taiwan
- Volunteers
- 113 people
- Sponsor
- Chang Gung University of Science and Technology
Parkinson Disease (PD)
Effects of Repetitive Transcranial Magnetic Stimulation (rTMS)-Primed Self-controlled Practice in People With Parkinson's Disease
Parkinson's disease (PD) is commonly associated with impaired motor learning and reduced motivation, both of which can negatively influence rehabilitation outcomes.
- Trial name
- NCT07832695
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS), Physical therapy
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- National Taiwan University Hospital
Prostate Cancer
Predictive and Prognostic Markers for Treatment Outcomes in Prostate Cancer Patients
The study aims to identify potential urine marker metabolites as predictive or prognostic markers for treatment outcomes in patients with prostate cancer.
- Trial name
- NCT03237026
- Testing
- No intervention required
- Where
- Taiwan
- Volunteers
- 360 people
- Sponsor
- National Taiwan University Hospital
Atrial Fibrillation
Exercise Training to Atrial Fibrillation
To test the impacts of different exercise training programs to the cardiopulmonary function, muscle metabolism, and body mass composition
- Trial name
- ExAF (NCT04508478)
- Testing
- Aerobic training, Resistance training, Control physical exercise
- Where
- Taiwan
- Volunteers
- 8 people
- Sponsor
- National Taiwan University Hospital
Malignant Biliary Obstruction, Malignant Biliary Stricture
Endoscopic Ultrasound Guided Hepaticogastrostomy With or Without Antegrade Stenting for Palliation of Malignant Distal Biliary Obstruction: Randomized Controlled Trial
The purpose of this study is to compare the efficacy and safety between EUS-HGAS and EUS-HGS. We hypothesized that EUS-HGAS provides lower recurrent biliary obstruction (RBO) rate but with a comparable safety profile to EUS-HGS.
- Trial name
- EASE-MBO (NCT07832045)
- Testing
- HGAS, HGS
- Where
- Taiwan
- Volunteers
- 88 people
- Sponsor
- National Taiwan University Hospital
Esophageal Squamous Cell Carcinoma
Sacituzumab Govitecan for Advanced Esophageal Squamous Cell Carcinoma
The goal of this clinical trial is to investigate the efficacy and safety of sacituzumab govitecan in patients with advanced esophageal squamous cell carcinoma.
- Trial name
- SG-ESCC (NCT06329869)
- Testing
- Sacituzumab govitecan
- Where
- Taiwan
- Volunteers
- 35 people
- Sponsor
- National Taiwan University Hospital
Osteoarthritis (OA) of the Knee
Comparison of Effectiveness Between PL and PRP on Knee Osteoarthritis: a Prospective,Randomized,Placebo-controlled Trial
This study will focus on grade I to III knee osteoarthritis by randomized controlled trials which comparing the effectiveness between placebo, autologous platelet rich plasma and autologous platelet lysate injections.
- Trial name
- NCT03734900
- Testing
- Saline injection, PRP injection, PL injection
- Where
- Taiwan
- Volunteers
- 150 people
- Sponsor
- National Taiwan University Hospital
Terminal Cancer, Hospice
Exploring Indications and Practices of Administering Artificial Hydration to Terminal Cancer Patients in Taiwan
Background: The issue of artificial hydration for terminal cancer patients is a classic ethical dilemma in palliative care. It is a common practice especially when patients are incapable of oral intake; however, there is a lack…
- Conditions
- Terminal Cancer, Hospice, Palliative Medicine
- Trial name
- NCT06329856
- Testing
- Administering of artificial hydration
- Where
- Taiwan
- Volunteers
- 391 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
rTMS Stimulation, Autonomy
Repetitive Transcranial Magnetic Stimulation Primed Self-controlled Practice on Motor Learning
This study aims to investigate the additive effects of combining self-controlled practice with repetitive transcranial magnetic stimulation (rTMS) pretreatment on motivation enhancement and motor learning performance in healthy…
- Conditions
- rTMS Stimulation, Autonomy, Healthy Young Adults
- Trial name
- NCT07197346
- Testing
- rTMS - cTBS (Continuous Theta-Burst Stimulation), Self-controlled (autonomy), Yoked Practice
- Where
- Taiwan
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Rare Diseases
DeciFace: Decipher the Influence of Ethnic Backgrounds on the Facial Dysmorphic Features of Rare Mendelian Disorders
There are more than 7000 known genetic disorders, and the number of affected is estimated to be about 6-10% of the population. Around 30 to 40% of genetic disorders have physical changes in the face and skull such as Down's…
- Trial name
- NCT05913843
- Testing
- Take photo
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Cognitive Training
The Training Effects of Tinkering Activities on Cognitive Flexibility in Older Adults From Communities
Aging has been a serious global-wise concern in public health. In particular, elders face declination of cognitive functions that threaten their quality of life.
- Trial name
- NCT05358145
- Testing
- Tinkering Activities, Control Tinkering Activities, Board Games Activities
- Where
- 2 sites in Taiwan
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Cardiac Arrest
Monitoring and Optimization of Cerebral Perfusion Pressure in Post-cardiac Arrest Patients: a Pilot Study
The goal of this study is to establish the ICP and CPP monitoring process and analyze the results in post-arrest patients, to validate the correlation between direct and non-invasive ICP monitoring indicators, to establish a…
- Trial name
- NCT06601842
- Testing
- ICP monitoring
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- National Taiwan University Hospital
Cardiac Arrest
Carotid Ultrasound Under Pulsed-wave Doppler Mode to Check the Pulse in Cardiopulmonary Arrest Patients.
It's crucial to determine whether a pulse is present or not in patient with cardiac arrest. But more and more studies have shown that manual palpation is unreliable for detecting pulse 1-4.
- Trial name
- NCT04790396
- Testing
- Carotid ultrasound under pulsed-wave doppler mode
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- National Taiwan University Hospital
Parkinson Disease, Gait Disorders, Neurologic
Benefits of Different Exercise Types to Enhance Walking for PD
Background: Gait disturbance is one of the most common complaints from patients with Parkinson's disease (PD). It is well-established that people with PD have motor learning impairments.
- Trial name
- NCT04895787
- Testing
- Gait + aerobic exercise, Gait + resistance exercises, Gait + conventional physical therapy
- Where
- Taiwan
- Volunteers
- 70 people
- Sponsor
- National Taiwan University Hospital
Parkinson Disease
Self-controlled Practice on Motor Learning and Motivation in Parkinson's Disease
People with Parkinson's disease have been known to have low motivation and motor learning impairment, which might limit the effectiveness of neurorehabilitation, exacerbate motor performance and quality of life, and increase the…
- Trial name
- NCT07028515
- Where
- Taiwan
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Primary Central Nervous System Lymphoma (PCNSL)
Rituximab, Acalabrutinib, and Durvalumab (RAD) in Primary CNS Lymphoma.
To evaluate the safety and tolerability and determine the recommended phase 2/phase 3 dose of RAD regimen in PCNSL
- Trial name
- NCT04688151
- Testing
- Rituximab
- Where
- Taiwan
- Volunteers
- 22 people
- Sponsor
- National Health Research Institutes, Taiwan
Extrapulmonary Small Cell Carcinoma and Neuroendocrine Carcinoma
Tarlatamab for Advanced Extrapulmonary Small Cell Carcinoma and Neuroendocrine Carcinoma (TAURUS)
Extrapulmonary small cell carcinoma (EPSCC) or neuroendocrine carcinoma (NEC) is a rare but fatal disease. The prognosis of patients with advanced EPSCC or NEC failed platinum-etoposide chemotherapy is poor with median overall…
- Trial name
- TAURUS (NCT06816394)
- Testing
- Tarlatamab
- Where
- Taiwan
- Volunteers
- 32 people
- Sponsor
- National Taiwan University Hospital
Cholelithiasis, Choledocholithiasis
Using da Vinci SP System for Patients With Cholelithiasis and Choledocholithiasis
A prospective, interventional, single arm study to investigate clinical feasibility of single-stage cholecystectomy and common bile duct exploration using da Vinci SP Surgical System (robotic surgery)
- Trial name
- NCT06852937
- Testing
- da Vinci SP Surgery System
- Where
- Taiwan
- Volunteers
- 24 people
- Sponsor
- National Taiwan University Hospital
Metabolic Syndrome, Diabetes
Metabolic Syndrome and Prediabetes
This study aims to establish a cohort of individuals with metabolic syndrome and prediabetes to enable long-term follow-up of risk factors, disease progression, and the development of obesity-related complications.
- Trial name
- NCT07243821
- Where
- Taiwan
- Volunteers
- 2,000 people
- Sponsor
- National Taiwan University Hospital
Parkinson Disease
Visuomotor Control in Parkinson Disease
Visuomotor processing is the ability to integrate visual information into motor plans and movement correction, which is highly required in daily activities such as writing and walking.
- Trial name
- NCT06918938
- Where
- Taiwan
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital